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Items: 13

1.

Gene-by-Environment Interaction of Bcrp-/- and Methionine- and Choline-Deficient Diet-Induced Nonalcoholic Steatohepatitis Alters SN-38 Disposition.

Toth EL, Li H, Dzierlenga AL, Clarke JD, Vildhede A, Goedken M, Cherrington NJ.

Drug Metab Dispos. 2018 Nov;46(11):1478-1486. doi: 10.1124/dmd.118.082081. Epub 2018 Aug 30.

PMID:
30166404
2.

Misregulation of membrane trafficking processes in human nonalcoholic steatohepatitis.

Dzierlenga AL, Cherrington NJ.

J Biochem Mol Toxicol. 2018 Mar;32(3):e22035. doi: 10.1002/jbt.22035. Epub 2018 Jan 17.

PMID:
29341352
3.

Metabolomic profiling distinction of human nonalcoholic fatty liver disease progression from a common rat model.

Han J, Dzierlenga AL, Lu Z, Billheimer DD, Torabzadeh E, Lake AD, Li H, Novak P, Shipkova P, Aranibar N, Robertson D, Reily MD, Lehman-McKeeman LD, Cherrington NJ.

Obesity (Silver Spring). 2017 Jun;25(6):1069-1076. doi: 10.1002/oby.21855. Epub 2017 Apr 28.

4.

In vivo cytochrome P450 activity alterations in diabetic nonalcoholic steatohepatitis mice.

Li H, Clarke JD, Dzierlenga AL, Bear J, Goedken MJ, Cherrington NJ.

J Biochem Mol Toxicol. 2017 Feb;31(2). doi: 10.1002/jbt.21840. Epub 2016 Oct 6.

5.

Nonalcoholic Steatohepatitis Modulates Membrane Protein Retrieval and Insertion Processes.

Dzierlenga AL, Clarke JD, Cherrington NJ.

Drug Metab Dispos. 2016 Nov;44(11):1799-1807. Epub 2016 Sep 7.

6.

Effect of nonalcoholic steatohepatitis on renal filtration and secretion of adefovir.

Laho T, Clarke JD, Dzierlenga AL, Li H, Klein DM, Goedken M, Micuda S, Cherrington NJ.

Biochem Pharmacol. 2016 Sep 1;115:144-51. doi: 10.1016/j.bcp.2016.07.001. Epub 2016 Jul 2.

7.

Biliary Elimination of Pemetrexed Is Dependent on Mrp2 in Rats: Potential Mechanism of Variable Response in Nonalcoholic Steatohepatitis.

Dzierlenga AL, Clarke JD, Klein DM, Anumol T, Snyder SA, Li H, Cherrington NJ.

J Pharmacol Exp Ther. 2016 Aug;358(2):246-53. doi: 10.1124/jpet.116.234310. Epub 2016 May 27.

8.

Mechanism of Altered Metformin Distribution in Nonalcoholic Steatohepatitis.

Clarke JD, Dzierlenga AL, Nelson NR, Li H, Werts S, Goedken MJ, Cherrington NJ.

Diabetes. 2015 Sep;64(9):3305-13. doi: 10.2337/db14-1947. Epub 2015 May 27.

9.

Mechanistic basis of altered morphine disposition in nonalcoholic steatohepatitis.

Dzierlenga AL, Clarke JD, Hargraves TL, Ainslie GR, Vanderah TW, Paine MF, Cherrington NJ.

J Pharmacol Exp Ther. 2015 Mar;352(3):462-70. doi: 10.1124/jpet.114.220764. Epub 2014 Dec 15.

10.

Renal xenobiotic transporter expression is altered in multiple experimental models of nonalcoholic steatohepatitis.

Canet MJ, Hardwick RN, Lake AD, Dzierlenga AL, Clarke JD, Goedken MJ, Cherrington NJ.

Drug Metab Dispos. 2015 Feb;43(2):266-72. doi: 10.1124/dmd.114.060574. Epub 2014 Dec 8.

11.

The reduction rates of DEPC-modified mutant Thermus thermophilus Rieske proteins differ when there is a negative charge proximal to the cluster.

Karagas NE, Jones CN, Osborn DJ, Dzierlenga AL, Oyala P, Konkle ME, Whitney EM, David Britt R, Hunsicker-Wang LM.

J Biol Inorg Chem. 2014 Oct;19(7):1121-35. doi: 10.1007/s00775-014-1167-9. Epub 2014 Jun 11.

PMID:
24916128
12.

Modeling human nonalcoholic steatohepatitis-associated changes in drug transporter expression using experimental rodent models.

Canet MJ, Hardwick RN, Lake AD, Dzierlenga AL, Clarke JD, Cherrington NJ.

Drug Metab Dispos. 2014 Apr;42(4):586-95. doi: 10.1124/dmd.113.055996. Epub 2014 Jan 2.

13.

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