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Items: 1 to 50 of 131

1.

Comparing surgical and nonsurgical larynx-preserving treatments with total laryngectomy for locally advanced laryngeal cancer.

Patel SA, Qureshi MM, Dyer MA, Jalisi S, Grillone G, Truong MT.

Cancer. 2019 Jun 17. doi: 10.1002/cncr.32292. [Epub ahead of print]

PMID:
31206637
2.

Correction to: Imaging features of immune-mediated genitourinary disease.

Kerekes RA, Martins RAP, Davis D, Karakaya M, Gleason S, Dyer MA.

Neurochem Res. 2019 Jul;44(7):1780. doi: 10.1007/s11064-019-02811-7.

PMID:
31104195
3.

The Clonal Evolution of Metastatic Osteosarcoma as Shaped by Cisplatin Treatment.

Brady SW, Ma X, Bahrami A, Satas G, Wu G, Newman S, Rusch M, Putnam DK, Mulder HL, Yergeau DA, Edmonson MN, Easton J, Alexandrov LB, Chen X, Mardis ER, Wilson RK, Downing JR, Pappo AS, Raphael BJ, Dyer MA, Zhang J.

Mol Cancer Res. 2019 Apr;17(4):895-906. doi: 10.1158/1541-7786.MCR-18-0620. Epub 2019 Jan 16.

PMID:
30651371
4.

Optimal sequencing of chemoradiotherapy for locally advanced laryngeal cancer.

Shah NK, Qureshi MM, Dyer MA, Patel SA, Kim K, Everett PC, Grillone GA, Jalisi SM, Truong MT.

Laryngoscope. 2019 Jan 9. doi: 10.1002/lary.27771. [Epub ahead of print]

PMID:
30628077
5.

Genome-wide discovery of somatic coding and noncoding mutations in pediatric endemic and sporadic Burkitt lymphoma.

Grande BM, Gerhard DS, Jiang A, Griner NB, Abramson JS, Alexander TB, Allen H, Ayers LW, Bethony JM, Bhatia K, Bowen J, Casper C, Choi JK, Culibrk L, Davidsen TM, Dyer MA, Gastier-Foster JM, Gesuwan P, Greiner TC, Gross TG, Hanf B, Harris NL, He Y, Irvin JD, Jaffe ES, Jones SJM, Kerchan P, Knoetze N, Leal FE, Lichtenberg TM, Ma Y, Martin JP, Martin MR, Mbulaiteye SM, Mullighan CG, Mungall AJ, Namirembe C, Novik K, Noy A, Ogwang MD, Omoding A, Orem J, Reynolds SJ, Rushton CK, Sandlund JT, Schmitz R, Taylor C, Wilson WH, Wright GW, Zhao EY, Marra MA, Morin RD, Staudt LM.

Blood. 2019 Mar 21;133(12):1313-1324. doi: 10.1182/blood-2018-09-871418. Epub 2019 Jan 7.

6.

Evaluation of drug information resources for drug-ethanol and drug-tobacco interactions.

Beckett RD, Stump CD, Dyer MA.

J Med Libr Assoc. 2019 Jan;107(1):62-71. doi: 10.5195/jmla.2019.549. Epub 2019 Jan 1.

7.

Combinatorial screening using orthotopic patient derived xenograft-expanded early phase cultures of osteosarcoma identify novel therapeutic drug combinations.

Loh AHP, Stewart E, Bradley CL, Chen X, Daryani V, Stewart CF, Calabrese C, Funk A, Miller G, Karlstrom A, Krafcik F, Goshorn DR, Vogel P, Bahrami A, Shelat A, Dyer MA.

Cancer Lett. 2019 Feb 1;442:262-270. doi: 10.1016/j.canlet.2018.10.033. Epub 2018 Nov 3.

PMID:
30395907
8.

Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses.

Stewart E, McEvoy J, Wang H, Chen X, Honnell V, Ocarz M, Gordon B, Dapper J, Blankenship K, Yang Y, Li Y, Shaw TI, Cho JH, Wang X, Xu B, Gupta P, Fan Y, Liu Y, Rusch M, Griffiths L, Jeon J, Freeman BB 3rd, Clay MR, Pappo A, Easton J, Shurtleff S, Shelat A, Zhou X, Boggs K, Mulder H, Yergeau D, Bahrami A, Mardis ER, Wilson RK, Zhang J, Peng J, Downing JR, Dyer MA; St. Jude Children's Research Hospital – Washington University Pediatric Cancer Genome Project.

Cancer Cell. 2018 Sep 10;34(3):411-426.e19. doi: 10.1016/j.ccell.2018.07.012. Epub 2018 Aug 23.

PMID:
30146332
9.

Development and Calibration of a Mathematical Model of Anal Carcinogenesis for High-Risk HIV-Infected Men.

Burger EA, Dyer MA, Sy S, Palefsky JM, de Pokomandy A, Coutlee F, Silverberg MJ, Kim JJ.

J Acquir Immune Defic Syndr. 2018 Sep 1;79(1):10-19. doi: 10.1097/QAI.0000000000001727.

PMID:
29757775
10.

Retinal Cell Type DNA Methylation and Histone Modifications Predict Reprogramming Efficiency and Retinogenesis in 3D Organoid Cultures.

Wang L, Hiler D, Xu B, AlDiri I, Chen X, Zhou X, Griffiths L, Valentine M, Shirinifard A, Sablauer A, Thiagarajan S, Barabas ME, Zhang J, Johnson D, Frase S, Dyer MA.

Cell Rep. 2018 Mar 6;22(10):2601-2614. doi: 10.1016/j.celrep.2018.01.075.

11.

The role of interleukin-2, all-trans retinoic acid, and natural killer cells: surveillance mechanisms in anti-GD2 antibody therapy in neuroblastoma.

Nguyen R, Houston J, Chan WK, Finkelstein D, Dyer MA.

Cancer Immunol Immunother. 2018 Apr;67(4):615-626. doi: 10.1007/s00262-017-2108-6. Epub 2018 Jan 11.

12.

Orthotopic patient-derived xenografts of paediatric solid tumours.

Stewart E, Federico SM, Chen X, Shelat AA, Bradley C, Gordon B, Karlstrom A, Twarog NR, Clay MR, Bahrami A, Freeman BB 3rd, Xu B, Zhou X, Wu J, Honnell V, Ocarz M, Blankenship K, Dapper J, Mardis ER, Wilson RK, Downing J, Zhang J, Easton J, Pappo A, Dyer MA.

Nature. 2017 Sep 7;549(7670):96-100. doi: 10.1038/nature23647. Epub 2017 Aug 30.

13.

The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis.

Aldiri I, Xu B, Wang L, Chen X, Hiler D, Griffiths L, Valentine M, Shirinifard A, Thiagarajan S, Sablauer A, Barabas ME, Zhang J, Johnson D, Frase S, Zhou X, Easton J, Zhang J, Mardis ER, Wilson RK, Downing JR, Dyer MA; St. Jude Children’s Research Hospital—Washington University Pediatric Cancer Genome Project.

Neuron. 2017 May 3;94(3):550-568.e10. doi: 10.1016/j.neuron.2017.04.022.

14.

Performance of a docking/molecular dynamics protocol for virtual screening of nutlin-class inhibitors of Mdmx.

Bharatham N, Finch KE, Min J, Mayasundari A, Dyer MA, Guy RK, Bashford D.

J Mol Graph Model. 2017 Jun;74:54-60. doi: 10.1016/j.jmgm.2017.02.014. Epub 2017 Feb 24.

15.

ATRX and DAXX: Mechanisms and Mutations.

Dyer MA, Qadeer ZA, Valle-Garcia D, Bernstein E.

Cold Spring Harb Perspect Med. 2017 Mar 1;7(3). pii: a026567. doi: 10.1101/cshperspect.a026567. Review.

16.

Biomedicine: An eye on retinal recovery.

Dyer MA.

Nature. 2016 Dec 15;540(7633):350-351. doi: 10.1038/nature20487. Epub 2016 Nov 30. No abstract available.

PMID:
27919071
17.

Reprogramming of mouse retinal neurons and standardized quantification of their differentiation in 3D retinal cultures.

Hiler DJ, Barabas ME, Griffiths LM, Dyer MA.

Nat Protoc. 2016 Oct;11(10):1955-1976. doi: 10.1038/nprot.2016.109. Epub 2016 Sep 15.

18.

Lessons from Retinoblastoma: Implications for Cancer, Development, Evolution, and Regenerative Medicine.

Dyer MA.

Trends Mol Med. 2016 Oct;22(10):863-876. doi: 10.1016/j.molmed.2016.07.010. Epub 2016 Aug 23. Review.

19.

Stem Cells Expand Insights into Human Brain Evolution.

Dyer MA.

Cell Stem Cell. 2016 Apr 7;18(4):425-6. doi: 10.1016/j.stem.2016.03.017.

20.

ATRX binds to atypical chromatin domains at the 3' exons of zinc finger genes to preserve H3K9me3 enrichment.

Valle-García D, Qadeer ZA, McHugh DS, Ghiraldini FG, Chowdhury AH, Hasson D, Dyer MA, Recillas-Targa F, Bernstein E.

Epigenetics. 2016 Jun 2;11(6):398-414. doi: 10.1080/15592294.2016.1169351. Epub 2016 Mar 30.

21.

Monitoring Ligand-Induced Protein Ordering in Drug Discovery.

Grace CR, Ban D, Min J, Mayasundari A, Min L, Finch KE, Griffiths L, Bharatham N, Bashford D, Kiplin Guy R, Dyer MA, Kriwacki RW.

J Mol Biol. 2016 Mar 27;428(6):1290-1303. doi: 10.1016/j.jmb.2016.01.016. Epub 2016 Jan 23.

22.

Ipilmumab and cranial radiation in metastatic melanoma patients: a case series and review.

Schoenfeld JD, Mahadevan A, Floyd SR, Dyer MA, Catalano PJ, Alexander BM, McDermott DF, Kaplan ID.

J Immunother Cancer. 2015 Dec 15;3:50. doi: 10.1186/s40425-015-0095-8. eCollection 2015.

23.

Brg1 coordinates multiple processes during retinogenesis and is a tumor suppressor in retinoblastoma.

Aldiri I, Ajioka I, Xu B, Zhang J, Chen X, Benavente C, Finkelstein D, Johnson D, Akiyama J, Pennacchio LA, Dyer MA.

Development. 2015 Dec 1;142(23):4092-106. doi: 10.1242/dev.124800.

24.

Preclinical Models Provide Scientific Justification and Translational Relevance for Moving Novel Therapeutics into Clinical Trials for Pediatric Cancer.

Langenau DM, Sweet-Cordero A, Wechsler-Reya R, Dyer MA.

Cancer Res. 2015 Dec 15;75(24):5176-5186. doi: 10.1158/0008-5472.CAN-15-1308. Epub 2015 Dec 1. Review.

25.

TNF Counterbalances the Emergence of M2 Tumor Macrophages.

Kratochvill F, Neale G, Haverkamp JM, Van de Velde LA, Smith AM, Kawauchi D, McEvoy J, Roussel MF, Dyer MA, Qualls JE, Murray PJ.

Cell Rep. 2015 Sep 22;12(11):1902-14. doi: 10.1016/j.celrep.2015.08.033. Epub 2015 Sep 10.

26.

Genetic and Epigenetic Discoveries in Human Retinoblastoma.

McEvoy JD, Dyer MA.

Crit Rev Oncog. 2015;20(3-4):217-25. Review.

27.

Progress in Small Molecule Therapeutics for the Treatment of Retinoblastoma.

Pritchard EM, Dyer MA, Guy RK.

Mini Rev Med Chem. 2016;16(6):430-54. Review.

28.

Quantification of Retinogenesis in 3D Cultures Reveals Epigenetic Memory and Higher Efficiency in iPSCs Derived from Rod Photoreceptors.

Hiler D, Chen X, Hazen J, Kupriyanov S, Carroll PA, Qu C, Xu B, Johnson D, Griffiths L, Frase S, Rodriguez AR, Martin G, Zhang J, Jeon J, Fan Y, Finkelstein D, Eisenman RN, Baldwin K, Dyer MA.

Cell Stem Cell. 2015 Jul 2;17(1):101-15. doi: 10.1016/j.stem.2015.05.015.

29.

The Childhood Solid Tumor Network: A new resource for the developmental biology and oncology research communities.

Stewart E, Federico S, Karlstrom A, Shelat A, Sablauer A, Pappo A, Dyer MA.

Dev Biol. 2016 Mar 15;411(2):287-293. doi: 10.1016/j.ydbio.2015.03.001. Epub 2015 Jun 9.

30.

A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis.

Moriarity BS, Otto GM, Rahrmann EP, Rathe SK, Wolf NK, Weg MT, Manlove LA, LaRue RS, Temiz NA, Molyneux SD, Choi K, Holly KJ, Sarver AL, Scott MC, Forster CL, Modiano JF, Khanna C, Hewitt SM, Khokha R, Yang Y, Gorlick R, Dyer MA, Largaespada DA.

Nat Genet. 2015 Jun;47(6):615-24. doi: 10.1038/ng.3293. Epub 2015 May 11.

31.

CONSERTING: integrating copy-number analysis with structural-variation detection.

Chen X, Gupta P, Wang J, Nakitandwe J, Roberts K, Dalton JD, Parker M, Patel S, Holmfeldt L, Payne D, Easton J, Ma J, Rusch M, Wu G, Patel A, Baker SJ, Dyer MA, Shurtleff S, Espy S, Pounds S, Downing JR, Ellison DW, Mullighan CG, Zhang J.

Nat Methods. 2015 Jun;12(6):527-30. doi: 10.1038/nmeth.3394. Epub 2015 May 4.

32.

Development and characterization of a human orthotopic neuroblastoma xenograft.

Stewart E, Shelat A, Bradley C, Chen X, Federico S, Thiagarajan S, Shirinifard A, Bahrami A, Pappo A, Qu C, Finkelstein D, Sablauer A, Dyer MA.

Dev Biol. 2015 Nov 15;407(2):344-55. doi: 10.1016/j.ydbio.2015.02.002. Epub 2015 Apr 9.

33.

Systematic Screening Identifies Dual PI3K and mTOR Inhibition as a Conserved Therapeutic Vulnerability in Osteosarcoma.

Gupte A, Baker EK, Wan SS, Stewart E, Loh A, Shelat AA, Gould CM, Chalk AM, Taylor S, Lackovic K, Karlström Å, Mutsaers AJ, Desai J, Madhamshettiwar PB, Zannettino AC, Burns C, Huang DC, Dyer MA, Simpson KJ, Walkley CR.

Clin Cancer Res. 2015 Jul 15;21(14):3216-29. doi: 10.1158/1078-0432.CCR-14-3026. Epub 2015 Apr 10.

34.

Genomic landscape of paediatric adrenocortical tumours.

Pinto EM, Chen X, Easton J, Finkelstein D, Liu Z, Pounds S, Rodriguez-Galindo C, Lund TC, Mardis ER, Wilson RK, Boggs K, Yergeau D, Cheng J, Mulder HL, Manne J, Jenkins J, Mastellaro MJ, Figueiredo BC, Dyer MA, Pappo A, Zhang J, Downing JR, Ribeiro RC, Zambetti GP.

Nat Commun. 2015 Mar 6;6:6302. doi: 10.1038/ncomms7302.

35.

Pediatric solid tumor genomics and developmental pliancy.

Chen X, Pappo A, Dyer MA.

Oncogene. 2015 Oct 8;34(41):5207-15. doi: 10.1038/onc.2014.474. Epub 2015 Feb 2. Review.

36.

Genetically engineered mouse and orthotopic human tumor xenograft models of retinoblastoma.

Benavente CA, Dyer MA.

Methods Mol Biol. 2015;1267:307-17. doi: 10.1007/978-1-4939-2297-0_15.

PMID:
25636476
37.

Genetics and epigenetics of human retinoblastoma.

Benavente CA, Dyer MA.

Annu Rev Pathol. 2015;10:547-62. doi: 10.1146/annurev-pathol-012414-040259. Review.

PMID:
25621664
38.

Targeting the DNA repair pathway in Ewing sarcoma.

Stewart E, Goshorn R, Bradley C, Griffiths LM, Benavente C, Twarog NR, Miller GM, Caufield W, Freeman BB 3rd, Bahrami A, Pappo A, Wu J, Loh A, Karlström Å, Calabrese C, Gordon B, Tsurkan L, Hatfield MJ, Potter PM, Snyder SE, Thiagarajan S, Shirinifard A, Sablauer A, Shelat AA, Dyer MA.

Cell Rep. 2014 Nov 6;9(3):829-41. doi: 10.1016/j.celrep.2014.09.028. Epub 2014 Oct 23.

39.

Chromatin remodelers HELLS and UHRF1 mediate the epigenetic deregulation of genes that drive retinoblastoma tumor progression.

Benavente CA, Finkelstein D, Johnson DA, Marine JC, Ashery-Padan R, Dyer MA.

Oncotarget. 2014 Oct 30;5(20):9594-608.

40.

Post-transcriptional gene expression control by NANOS is up-regulated and functionally important in pRb-deficient cells.

Miles WO, Korenjak M, Griffiths LM, Dyer MA, Provero P, Dyson NJ.

EMBO J. 2014 Oct 1;33(19):2201-15. doi: 10.15252/embj.201488057. Epub 2014 Aug 6.

41.

The role of whole brain radiation therapy in the management of melanoma brain metastases.

Dyer MA, Arvold ND, Chen YH, Pinnell NE, Mitin T, Lee EQ, Hodi FS, Ibrahim N, Weiss SE, Kelly PJ, Floyd SR, Mahadevan A, Alexander BM.

Radiat Oncol. 2014 Jun 22;9:143. doi: 10.1186/1748-717X-9-143.

42.

Pharmacokinetics and efficacy of the spleen tyrosine kinase inhibitor r406 after ocular delivery for retinoblastoma.

Pritchard EM, Stewart E, Zhu F, Bradley C, Griffiths L, Yang L, Suryadevara PK, Zhang J, Freeman BB 3rd, Guy RK, Dyer MA.

Pharm Res. 2014 Nov;31(11):3060-72. doi: 10.1007/s11095-014-1399-y. Epub 2014 Jun 7.

43.

The ATRX cDNA is prone to bacterial IS10 element insertions that alter its structure.

Valle-García D, Griffiths LM, Dyer MA, Bernstein E, Recillas-Targa F.

Springerplus. 2014 May 2;3:222. doi: 10.1186/2193-1801-3-222. eCollection 2014.

44.

Recurrent somatic structural variations contribute to tumorigenesis in pediatric osteosarcoma.

Chen X, Bahrami A, Pappo A, Easton J, Dalton J, Hedlund E, Ellison D, Shurtleff S, Wu G, Wei L, Parker M, Rusch M, Nagahawatte P, Wu J, Mao S, Boggs K, Mulder H, Yergeau D, Lu C, Ding L, Edmonson M, Qu C, Wang J, Li Y, Navid F, Daw NC, Mardis ER, Wilson RK, Downing JR, Zhang J, Dyer MA; St. Jude Children’s Research Hospital–Washington University Pediatric Cancer Genome Project.

Cell Rep. 2014 Apr 10;7(1):104-12. doi: 10.1016/j.celrep.2014.03.003. Epub 2014 Apr 3.

45.

RB1 gene inactivation by chromothripsis in human retinoblastoma.

McEvoy J, Nagahawatte P, Finkelstein D, Richards-Yutz J, Valentine M, Ma J, Mullighan C, Song G, Chen X, Wilson M, Brennan R, Pounds S, Becksfort J, Huether R, Lu C, Fulton RS, Fulton LL, Hong X, Dooling DJ, Ochoa K, Mardis ER, Wilson RK, Easton J, Zhang J, Downing JR, Ganguly A, Dyer MA.

Oncotarget. 2014 Jan 30;5(2):438-50.

46.

Targeting oxidative stress in embryonal rhabdomyosarcoma.

Chen X, Stewart E, Shelat AA, Qu C, Bahrami A, Hatley M, Wu G, Bradley C, McEvoy J, Pappo A, Spunt S, Valentine MB, Valentine V, Krafcik F, Lang WH, Wierdl M, Tsurkan L, Tolleman V, Federico SM, Morton C, Lu C, Ding L, Easton J, Rusch M, Nagahawatte P, Wang J, Parker M, Wei L, Hedlund E, Finkelstein D, Edmonson M, Shurtleff S, Boggs K, Mulder H, Yergeau D, Skapek S, Hawkins DS, Ramirez N, Potter PM, Sandoval JA, Davidoff AM, Mardis ER, Wilson RK, Zhang J, Downing JR, Dyer MA; St. Jude Children’s Research Hospital–Washington University Pediatric Cancer Genome Project.

Cancer Cell. 2013 Dec 9;24(6):710-24. doi: 10.1016/j.ccr.2013.11.002.

47.

Expression of podocalyxin separates the hematopoietic and vascular potentials of mouse embryonic stem cell-derived mesoderm.

Zhang H, Nieves JL, Fraser ST, Isern J, Douvaras P, Papatsenko D, D'Souza SL, Lemischka IR, Dyer MA, Baron MH.

Stem Cells. 2014 Jan;32(1):191-203. doi: 10.1002/stem.1536.

48.

Cross-species genomic and epigenomic landscape of retinoblastoma.

Benavente CA, McEvoy JD, Finkelstein D, Wei L, Kang G, Wang YD, Neale G, Ragsdale S, Valentine V, Bahrami A, Temirov J, Pounds S, Zhang J, Dyer MA.

Oncotarget. 2013 Jun;4(6):844-59.

49.

An Open Trial of Relapse Prevention Therapy for Smokers With Schizophrenia.

Cather C, Dyer MA, Burrell HA, Hoeppner B, Goff DC, Evins AE.

J Dual Diagn. 2013;9(1):87-93.

50.

Neuroblastoma: developmental biology, cancer genomics and immunotherapy.

Cheung NK, Dyer MA.

Nat Rev Cancer. 2013 Jun;13(6):397-411. doi: 10.1038/nrc3526. Review.

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