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Items: 16


Kinetics of CXCL12 binding to atypical chemokine receptor 3 reveal a role for the receptor N terminus in chemokine binding.

Gustavsson M, Dyer DP, Zhao C, Handel TM.

Sci Signal. 2019 Sep 10;12(598). pii: eaaw3657. doi: 10.1126/scisignal.aaw3657.


Chemokine Receptor Redundancy and Specificity Are Context Dependent.

Dyer DP, Medina-Ruiz L, Bartolini R, Schuette F, Hughes CE, Pallas K, Vidler F, Macleod MKL, Kelly CJ, Lee KM, Hansell CAH, Graham GJ.

Immunity. 2019 Feb 19;50(2):378-389.e5. doi: 10.1016/j.immuni.2019.01.009.


The chemokine receptor CXCR2 contributes to murine adipocyte development.

Dyer DP, Nebot JB, Kelly CJ, Medina-Ruiz L, Schuette F, Graham GJ.

J Leukoc Biol. 2019 Mar;105(3):497-506. doi: 10.1002/JLB.1A0618-216RR. Epub 2018 Dec 5.


Corrigendum: CXCR2 deficient mice display macrophage-dependent exaggerated acute inflammatory responses.

Dyer DP, Pallas K, Medina-Ruiz L, Schuette F, Wilson GJ, Graham GJ.

Sci Rep. 2017 Apr 10;7:45423. doi: 10.1038/srep45423. No abstract available.


CXCR2 deficient mice display macrophage-dependent exaggerated acute inflammatory responses.

Dyer DP, Pallas K, Medina-Ruiz L, Schuette F, Wilson GJ, Graham GJ.

Sci Rep. 2017 Feb 16;7:42681. doi: 10.1038/srep42681. Erratum in: Sci Rep. 2017 Apr 10;7:45423.


Differential structural remodelling of heparan sulfate by chemokines: the role of chemokine oligomerization.

Dyer DP, Migliorini E, Salanga CL, Thakar D, Handel TM, Richter RP.

Open Biol. 2017 Jan;7(1). pii: 160286. doi: 10.1098/rsob.160286.


The Anti-inflammatory Protein TSG-6 Regulates Chemokine Function by Inhibiting Chemokine/Glycosaminoglycan Interactions.

Dyer DP, Salanga CL, Johns SC, Valdambrini E, Fuster MM, Milner CM, Day AJ, Handel TM.

J Biol Chem. 2016 Jun 10;291(24):12627-40. doi: 10.1074/jbc.M116.720953. Epub 2016 Apr 4.


Examination of Glycosaminoglycan Binding Sites on the XCL1 Dimer.

Fox JC, Tyler RC, Peterson FC, Dyer DP, Zhang F, Linhardt RJ, Handel TM, Volkman BF.

Biochemistry. 2016 Mar 1;55(8):1214-25. doi: 10.1021/acs.biochem.5b01329. Epub 2016 Feb 17.


The dependence of chemokine-glycosaminoglycan interactions on chemokine oligomerization.

Dyer DP, Salanga CL, Volkman BF, Kawamura T, Handel TM.

Glycobiology. 2016 Mar;26(3):312-26. doi: 10.1093/glycob/cwv100. Epub 2015 Nov 17.


Cytokines and growth factors cross-link heparan sulfate.

Migliorini E, Thakar D, K├╝hnle J, Sadir R, Dyer DP, Li Y, Sun C, Volkman BF, Handel TM, Coche-Guerente L, Fernig DG, Lortat-Jacob H, Richter RP.

Open Biol. 2015 Aug;5(8). pii: 150046. doi: 10.1098/rsob.150046.


Identification of the pharmacophore of the CC chemokine-binding proteins Evasin-1 and -4 using phage display.

Bonvin P, Dunn SM, Rousseau F, Dyer DP, Shaw J, Power CA, Handel TM, Proudfoot AE.

J Biol Chem. 2014 Nov 14;289(46):31846-55. doi: 10.1074/jbc.M114.599233. Epub 2014 Sep 29.


Multiple glycosaminoglycan-binding epitopes of monocyte chemoattractant protein-3/CCL7 enable it to function as a non-oligomerizing chemokine.

Salanga CL, Dyer DP, Kiselar JG, Gupta S, Chance MR, Handel TM.

J Biol Chem. 2014 May 23;289(21):14896-912. doi: 10.1074/jbc.M114.547737. Epub 2014 Apr 11.


TSG-6 inhibits neutrophil migration via direct interaction with the chemokine CXCL8.

Dyer DP, Thomson JM, Hermant A, Jowitt TA, Handel TM, Proudfoot AE, Day AJ, Milner CM.

J Immunol. 2014 Mar 1;192(5):2177-85. doi: 10.4049/jimmunol.1300194. Epub 2014 Feb 5.


A refined model for the TSG-6 link module in complex with hyaluronan: use of defined oligosaccharides to probe structure and function.

Higman VA, Briggs DC, Mahoney DJ, Blundell CD, Sattelle BM, Dyer DP, Green DE, DeAngelis PL, Almond A, Milner CM, Day AJ.

J Biol Chem. 2014 Feb 28;289(9):5619-34. doi: 10.1074/jbc.M113.542357. Epub 2014 Jan 8.


Vascular access for acute haemodialysis.

Gibson TC, Dyer DP, Postlethwaite RJ, Gough DC.

Arch Dis Child. 1987 Feb;62(2):141-5.


A possible sensitive period for juvenile socialization in mice.

Dyer DP Jr, Southwick CH.

Behav Biol. 1974 Dec;12(4):551-8. No abstract available.


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