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Items: 8


Human lung organoids develop into adult airway-like structures directed by physico-chemical biomaterial properties.

Dye BR, Youngblood RL, Oakes RS, Kasputis T, Clough DW, Spence JR, Shea LD.

Biomaterials. 2020 Mar;234:119757. doi: 10.1016/j.biomaterials.2020.119757. Epub 2020 Jan 6.


Generation of lung organoids from human pluripotent stem cells in vitro.

Miller AJ, Dye BR, Ferrer-Torres D, Hill DR, Overeem AW, Shea LD, Spence JR.

Nat Protoc. 2019 Feb;14(2):518-540. doi: 10.1038/s41596-018-0104-8.


In Vitro Induction and In Vivo Engraftment of Lung Bud Tip Progenitor Cells Derived from Human Pluripotent Stem Cells.

Miller AJ, Hill DR, Nagy MS, Aoki Y, Dye BR, Chin AM, Huang S, Zhu F, White ES, Lama V, Spence JR.

Stem Cell Reports. 2018 Jan 9;10(1):101-119. doi: 10.1016/j.stemcr.2017.11.012. Epub 2017 Dec 14.


LGR4 and LGR5 Function Redundantly During Human Endoderm Differentiation.

Tsai YH, Hill DR, Kumar N, Huang S, Chin AM, Dye BR, Nagy MS, Verzi MP, Spence JR.

Cell Mol Gastroenterol Hepatol. 2016 Jun 23;2(5):648-662.e8. doi: 10.1016/j.jcmgh.2016.06.002. eCollection 2016 Sep.


A bioengineered niche promotes in vivo engraftment and maturation of pluripotent stem cell derived human lung organoids.

Dye BR, Dedhia PH, Miller AJ, Nagy MS, White ES, Shea LD, Spence JR.

Elife. 2016 Sep 28;5. pii: e19732. doi: 10.7554/eLife.19732.


Hox5 Genes Regulate the Wnt2/2b-Bmp4-Signaling Axis during Lung Development.

Hrycaj SM, Dye BR, Baker NC, Larsen BM, Burke AC, Spence JR, Wellik DM.

Cell Rep. 2015 Aug 11;12(6):903-12. doi: 10.1016/j.celrep.2015.07.020. Epub 2015 Jul 30.


In vitro generation of human pluripotent stem cell derived lung organoids.

Dye BR, Hill DR, Ferguson MA, Tsai YH, Nagy MS, Dyal R, Wells JM, Mayhew CN, Nattiv R, Klein OD, White ES, Deutsch GH, Spence JR.

Elife. 2015 Mar 24;4. doi: 10.7554/eLife.05098.

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