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Items: 1 to 50 of 63

1.

Functional role of miR-148a in oropharyngeal cancer: influence on pregnane X receptor and P-glycoprotein expression.

Reuter T, Herold-Mende C, Dyckhoff G, Rigalli JP, Weiss J.

J Recept Signal Transduct Res. 2019 Oct-Dec;39(5-6):451-459. doi: 10.1080/10799893.2019.1694541. Epub 2019 Nov 27.

PMID:
31771390
2.

Antibody Responses to Cancer Antigens Identify Patients with a Poor Prognosis among HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinoma Patients.

Laban S, Gangkofner DS, Holzinger D, Schroeder L, Eichmüller SB, Zörnig I, Jäger D, Wichmann G, Dietz A, Broglie MA, Herold-Mende CC, Dyckhoff G, Boscolo-Rizzo P, Ezić J, Marienfeld R, Möller P, Kraus JM, Völkel G, Kestler HA, Brunner C, Schuler PJ, Wigand MC, Theodoraki MN, Doescher J, Hoffmann TK, Pawlita M, Waterboer T, Butt J.

Clin Cancer Res. 2019 Dec 15;25(24):7405-7412. doi: 10.1158/1078-0432.CCR-19-1490. Epub 2019 Aug 23.

PMID:
31444248
3.

Absence of disruptive TP53 mutations in high-risk human papillomavirus-driven neck squamous cell carcinoma of unknown primary.

Boscolo-Rizzo P, Schroeder L, Sacchetto V, Holzinger D, Da Mosto MC, Tirelli G, Dal Cin E, Mantovani M, Menegaldo A, Del Mistro A, Romeo S, Dei Tos AP, Niero M, Rigo S, Dyckhoff G, Hess J, Alemany L, Quer M, León X, Polesel J, Pawlita M, Bertorelle R.

Head Neck. 2019 Nov;41(11):3833-3841. doi: 10.1002/hed.25915. Epub 2019 Aug 15.

PMID:
31414564
4.

Patterns of antibody responses to nonviral cancer antigens in head and neck squamous cell carcinoma patients differ by human papillomavirus status.

Gangkofner DS, Holzinger D, Schroeder L, Eichmüller SB, Zörnig I, Jäger D, Wichmann G, Dietz A, Broglie MA, Herold-Mende C, Dyckhoff G, Boscolo-Rizzo P, Ezic J, Marienfeld RB, Möller P, Völkel G, Kraus JM, Kestler HA, Brunner C, Schuler PJ, Wigand M, Theodoraki MN, Doescher J, Hoffmann TK, Pawlita M, Butt J, Waterboer T, Laban S.

Int J Cancer. 2019 Dec 15;145(12):3436-3444. doi: 10.1002/ijc.32623. Epub 2019 Aug 26.

PMID:
31407331
5.

What do laypeople consider 'medication' and are they aware of modulators of a drug's effects?

Send AFJ, Bittmann JA, Dyckhoff G, Haefeli WE, Seidling HM.

Eur J Hosp Pharm. 2018 Jul;25(4):218-221. doi: 10.1136/ejhpharm-2016-001086. Epub 2016 Nov 1.

6.

DNA methylation at an enhancer of the three prime repair exonuclease 2 gene (TREX2) is linked to gene expression and survival in laryngeal cancer.

Weigel C, Chaisaingmongkol J, Assenov Y, Kuhmann C, Winkler V, Santi I, Bogatyrova O, Kaucher S, Bermejo JL, Leung SY, Chan TL, Lasitschka F, Bohrer MH, Marx A, Haußen RH, Herold-Mende C, Dyckhoff G, Boukamp P, Delank KW, Hörmann K, Lippert BM, Baier G, Dietz A, Oakes CC, Plass C, Becher H, Schmezer P, Ramroth H, Popanda O.

Clin Epigenetics. 2019 May 3;11(1):67. doi: 10.1186/s13148-019-0666-5.

7.

Differential Activation of ERK Signaling in HPV-Related Oropharyngeal Squamous Cell Carcinoma.

Rong C, Muller M, Flechtenmacher C, Holzinger D, Dyckhoff G, Bulut OC, Horn D, Plinkert P, Hess J, Affolter A.

Cancers (Basel). 2019 Apr 25;11(4). pii: E584. doi: 10.3390/cancers11040584.

8.

Cortactin expression: Association with disease progression and survival in oral squamous cell carcinoma.

Horn D, Gross M, Dyckhoff G, Fuchs J, Grabe N, Weichert W, Herpel E, Herold-Mende C, Lichter P, Hoffmann J, Hess J, Freier K.

Head Neck. 2018 Dec;40(12):2685-2694. doi: 10.1002/hed.25515. Epub 2018 Nov 20.

PMID:
30456890
9.

Totale Laryngektomie: Wundinfektionen sind bei Diabetespatienten häufiger.

Dyckhoff G.

Laryngorhinootologie. 2018 May;97(5):301-302. doi: 10.1055/s-0043-121849. Epub 2018 May 2. German.

PMID:
29719887
10.

Human papilloma virus (HPV) 18 proteins E6 and E7 up-regulate ABC transporters in oropharyngeal carcinoma. Involvement of the nonsense-mediated decay (NMD) pathway.

Rigalli JP, Reichel M, Tocchetti GN, Reuter T, Dyckhoff G, Herold-Mende C, Weiss J.

Cancer Lett. 2018 Aug 1;428:69-76. doi: 10.1016/j.canlet.2018.04.036. Epub 2018 Apr 30.

PMID:
29715486
11.

Comparison of the RGD Motif-Containing αvβ6 Integrin-Binding Peptides SFLAP3 and SFITGv6 for Diagnostic Application in HNSCC.

Roesch S, Lindner T, Sauter M, Loktev A, Flechsig P, Müller M, Mier W, Warta R, Dyckhoff G, Herold-Mende C, Haberkorn U, Altmann A.

J Nucl Med. 2018 Nov;59(11):1679-1685. doi: 10.2967/jnumed.118.210013. Epub 2018 Apr 19.

12.

The pregnane X receptor (PXR) and the nuclear receptor corepressor 2 (NCoR2) modulate cell growth in head and neck squamous cell carcinoma.

Rigalli JP, Reichel M, Reuter T, Tocchetti GN, Dyckhoff G, Herold-Mende C, Theile D, Weiss J.

PLoS One. 2018 Feb 22;13(2):e0193242. doi: 10.1371/journal.pone.0193242. eCollection 2018.

13.

Upregulation of pAKT(Ser473) expression in progression of HPV-positive oropharyngeal squamous cell carcinoma.

Horn D, Freudlsperger C, Holzinger D, Kunzmann K, Plinkert P, Dyckhoff G, Hoffmann J, Freier K, Hess J.

Head Neck. 2017 Dec;39(12):2397-2405. doi: 10.1002/hed.24910. Epub 2017 Sep 25.

PMID:
28945300
14.

A change in the study evaluation paradigm reveals that larynx preservation compromises survival in T4 laryngeal cancer patients.

Dyckhoff G, Plinkert PK, Ramroth H.

BMC Cancer. 2017 Sep 1;17(1):609. doi: 10.1186/s12885-017-3608-7.

15.

Identification of a Novel ITGαvβ6-Binding Peptide Using Protein Separation and Phage Display.

Altmann A, Sauter M, Roesch S, Mier W, Warta R, Debus J, Dyckhoff G, Herold-Mende C, Haberkorn U.

Clin Cancer Res. 2017 Aug 1;23(15):4170-4180. doi: 10.1158/1078-0432.CCR-16-3217. Epub 2017 May 3.

16.

Human papillomavirus as prognostic marker with rising prevalence in neck squamous cell carcinoma of unknown primary: A retrospective multicentre study.

Schroeder L, Boscolo-Rizzo P, Dal Cin E, Romeo S, Baboci L, Dyckhoff G, Hess J, Lucena-Porcel C, Byl A, Becker N, Alemany L, Castellsagué X, Quer M, León X, Wiesenfarth M, Pawlita M, Holzinger D.

Eur J Cancer. 2017 Mar;74:73-81. doi: 10.1016/j.ejca.2016.12.020. Epub 2017 Feb 10.

PMID:
28335889
17.

Sensitivity and specificity of antibodies against HPV16 E6 and other early proteins for the detection of HPV16-driven oropharyngeal squamous cell carcinoma.

Holzinger D, Wichmann G, Baboci L, Michel A, Höfler D, Wiesenfarth M, Schroeder L, Boscolo-Rizzo P, Herold-Mende C, Dyckhoff G, Boehm A, Del Mistro A, Bosch FX, Dietz A, Pawlita M, Waterboer T.

Int J Cancer. 2017 Jun 15;140(12):2748-2757. doi: 10.1002/ijc.30697. Epub 2017 Apr 4.

18.

Comparative analysis of transcriptomics based hypoxia signatures in head- and neck squamous cell carcinoma.

Tawk B, Schwager C, Deffaa O, Dyckhoff G, Warta R, Linge A, Krause M, Weichert W, Baumann M, Herold-Mende C, Debus J, Abdollahi A.

Radiother Oncol. 2016 Feb;118(2):350-8. doi: 10.1016/j.radonc.2015.11.027. Epub 2015 Dec 19.

PMID:
26711490
19.

Role of NR1I2 (pregnane X receptor) polymorphisms in head and neck squamous cell carcinoma.

Reuter T, Warta R, Theile D, Meid AD, Rigalli JP, Mogler C, Herpel E, Grabe N, Lahrmann B, Plinkert PK, Herold-Mende C, Dyckhoff G, Haefeli WE, Weiss J.

Naunyn Schmiedebergs Arch Pharmacol. 2015 Nov;388(11):1141-50. doi: 10.1007/s00210-015-1150-1. Epub 2015 Jul 4.

PMID:
26141049
20.

Association of history of allergies and influenza-like infections with laryngeal cancer in a case-control study.

Filippidis FT, Schwartz SM, Becker N, Dyckhoff G, Kirschfink M, Dietz A, Becher H, Ramroth H.

Eur Arch Otorhinolaryngol. 2015 Aug;272(8):2063-9. doi: 10.1007/s00405-015-3528-6. Epub 2015 Jan 30.

PMID:
25634066
21.

An EGF receptor targeting Ranpirnase-diabody fusion protein mediates potent antitumour activity in vitro and in vivo.

Kiesgen S, Arndt MAE, Körber C, Arnold U, Weber T, Halama N, Keller A, Bötticher B, Schlegelmilch A, Liebers N, Cremer M, Herold-Mende C, Dyckhoff G, Federspil PA, Jensen AD, Jäger D, Kontermann RE, Mier W, Krauss J.

Cancer Lett. 2015 Feb 1;357(1):364-373. doi: 10.1016/j.canlet.2014.11.054. Epub 2014 Nov 27.

PMID:
25434798
22.

Phosphorylation of AKT(Ser473) serves as an independent prognostic marker for radiosensitivity in advanced head and neck squamous cell carcinoma.

Freudlsperger C, Horn D, Weißfuß S, Weichert W, Weber KJ, Saure D, Sharma S, Dyckhoff G, Grabe N, Plinkert P, Hoffmann J, Freier K, Hess J.

Int J Cancer. 2015 Jun 15;136(12):2775-85. doi: 10.1002/ijc.29328. Epub 2014 Nov 26.

23.

A fusogenic dengue virus-derived peptide enhances antitumor efficacy of an antibody-ribonuclease fusion protein targeting the EGF receptor.

Kiesgen S, Liebers N, Cremer M, Arnold U, Weber T, Keller A, Herold-Mende C, Dyckhoff G, Jäger D, Kontermann RE, Arndt MA, Krauss J.

Protein Eng Des Sel. 2014 Oct;27(10):331-7. doi: 10.1093/protein/gzu040.

PMID:
25301960
24.

Acinar cell carcinomas of the pancreas: a molecular analysis in a series of 57 cases.

Bergmann F, Aulmann S, Sipos B, Kloor M, von Heydebreck A, Schweipert J, Harjung A, Mayer P, Hartwig W, Moldenhauer G, Capper D, Dyckhoff G, Freier K, Herpel E, Schleider A, Schirmacher P, Mechtersheimer G, Klöppel G, Bläker H.

Virchows Arch. 2014 Dec;465(6):661-72. doi: 10.1007/s00428-014-1657-8. Epub 2014 Oct 9.

PMID:
25298229
25.

Association of drug transporter expression with mortality and progression-free survival in stage IV head and neck squamous cell carcinoma.

Warta R, Theile D, Mogler C, Herpel E, Grabe N, Lahrmann B, Plinkert PK, Herold-Mende C, Weiss J, Dyckhoff G.

PLoS One. 2014 Oct 2;9(9):e108908. doi: 10.1371/journal.pone.0108908. eCollection 2014.

26.

p16(INK4a) /Ki-67 co-expression specifically identifies transformed cells in the head and neck region.

Prigge ES, Toth C, Dyckhoff G, Wagner S, Müller F, Wittekindt C, Freier K, Plinkert P, Hoffmann J, Vinokurova S, Klussmann JP, von Knebel Doeberitz M, Reuschenbach M.

Int J Cancer. 2015 Apr 1;136(7):1589-99. doi: 10.1002/ijc.29130. Epub 2014 Aug 19.

27.

Long noncoding RNA TARID directs demethylation and activation of the tumor suppressor TCF21 via GADD45A.

Arab K, Park YJ, Lindroth AM, Schäfer A, Oakes C, Weichenhan D, Lukanova A, Lundin E, Risch A, Meister M, Dienemann H, Dyckhoff G, Herold-Mende C, Grummt I, Niehrs C, Plass C.

Mol Cell. 2014 Aug 21;55(4):604-14. doi: 10.1016/j.molcel.2014.06.031. Epub 2014 Jul 31.

28.

Reduced promoter methylation and increased expression of CSPG4 negatively influences survival of HNSCC patients.

Warta R, Herold-Mende C, Chaisaingmongkol J, Popanda O, Mock A, Mogler C, Osswald F, Herpel E, Küstner S, Eckstein V, Plass C, Plinkert P, Schmezer P, Dyckhoff G.

Int J Cancer. 2014 Dec 1;135(11):2727-34. doi: 10.1002/ijc.28906. Epub 2014 Apr 26.

29.

Antiproliferative efficacies but minor drug transporter inducing effects of paclitaxel, cisplatin, or 5-fluorouracil in a murine xenograft model for head and neck squamous cell carcinoma.

Theile D, Gal Z, Warta R, Rigalli JP, Lahrmann B, Grabe N, Herold-Mende C, Dyckhoff G, Weiss J.

Cancer Biol Ther. 2014 Apr;15(4):436-42. doi: 10.4161/cbt.27632. Epub 2014 Jan 21.

30.

Generation of “LYmph Node Derived Antibody Libraries” (LYNDAL) for selecting fully human antibody fragments with therapeutic potential.

Diebolder P, Keller A, Haase S, Schlegelmilch A, Kiefer JD, Karimi T, Weber T, Moldenhauer G, Kehm R, Eis-Hübinger AM, Jäger D, Federspil PA, Herold-Mende C, Dyckhoff G, Kontermann RE, Arndt MA, Krauss J.

MAbs. 2014 Jan-Feb;6(1):130-42.

31.

Biological evidence for a causal role of HPV16 in a small fraction of laryngeal squamous cell carcinoma.

Halec G, Holzinger D, Schmitt M, Flechtenmacher C, Dyckhoff G, Lloveras B, Höfler D, Bosch FX, Pawlita M.

Br J Cancer. 2013 Jul 9;109(1):172-83. doi: 10.1038/bjc.2013.296. Epub 2013 Jun 18.

32.

HPV-related methylation signature predicts survival in oropharyngeal squamous cell carcinomas.

Kostareli E, Holzinger D, Bogatyrova O, Hielscher T, Wichmann G, Keck M, Lahrmann B, Grabe N, Flechtenmacher C, Schmidt CR, Seiwert T, Dyckhoff G, Dietz A, Höfler D, Pawlita M, Benner A, Bosch FX, Plinkert P, Plass C, Weichenhan D, Hess J.

J Clin Invest. 2013 Jun;123(6):2488-501. doi: 10.1172/JCI67010. Epub 2013 May 1.

33.

Minor role of pregnane-x-receptor for acquired multidrug resistance in head and neck squamous cell carcinoma in vitro.

Rigalli JP, Reuter T, Herold-Mende C, Dyckhoff G, Haefeli WE, Weiss J, Theile D.

Cancer Chemother Pharmacol. 2013 May;71(5):1335-43. doi: 10.1007/s00280-013-2133-x. Epub 2013 Mar 12.

PMID:
23479137
34.

Viral RNA patterns and high viral load reliably define oropharynx carcinomas with active HPV16 involvement.

Holzinger D, Schmitt M, Dyckhoff G, Benner A, Pawlita M, Bosch FX.

Cancer Res. 2012 Oct 1;72(19):4993-5003. doi: 10.1158/0008-5472.CAN-11-3934. Epub 2012 Sep 18.

35.

Unmasked: when a clinically malignant disease turns out infectious. A rare case of tularemia.

Bulut OC, Dyckhoff G, Splettstoesser W, Nemeth J, Klauschen F, Penzel R, Plinkert PK, Simon C, Weichert W, Stenzinger A.

Int J Surg Pathol. 2013 Feb;21(1):76-81. doi: 10.1177/1066896912448424. Epub 2012 Jun 6. Review.

PMID:
22674915
36.

Quantification of retinoid concentrations in human serum and brain tumor tissues.

Ali R, Campos B, Dyckhoff G, Haefeli WE, Herold-Mende C, Burhenne J.

Anal Chim Acta. 2012 May 6;725:57-66. doi: 10.1016/j.aca.2012.03.003. Epub 2012 Mar 17.

PMID:
22502612
37.

Opposing function of MYBBP1A in proliferation and migration of head and neck squamous cell carcinoma cells.

Acuña Sanhueza GA, Faller L, George B, Koffler J, Misetic V, Flechtenmacher C, Dyckhoff G, Plinkert PP, Angel P, Simon C, Hess J.

BMC Cancer. 2012 Feb 17;12:72. doi: 10.1186/1471-2407-12-72.

38.

Epigenetic screen of human DNA repair genes identifies aberrant promoter methylation of NEIL1 in head and neck squamous cell carcinoma.

Chaisaingmongkol J, Popanda O, Warta R, Dyckhoff G, Herpel E, Geiselhart L, Claus R, Lasitschka F, Campos B, Oakes CC, Bermejo JL, Herold-Mende C, Plass C, Schmezer P.

Oncogene. 2012 Dec 6;31(49):5108-16. doi: 10.1038/onc.2011.660. Epub 2012 Jan 30.

PMID:
22286769
39.

Cellular pharmacokinetic/pharmacodynamic relationship of platinum cytostatics in head and neck squamous cell carcinoma evaluated by liquid chromatography coupled to tandem mass spectrometry.

Theile D, Detering JC, Herold-Mende C, Dyckhoff G, Haefeli WE, Weiss J, Burhenne J.

J Pharmacol Exp Ther. 2012 Apr;341(1):51-8. doi: 10.1124/jpet.111.189621. Epub 2011 Dec 29.

PMID:
22207655
40.

Factors predicting survival after diagnosis of laryngeal cancer.

Ramroth H, Schoeps A, Rudolph E, Dyckhoff G, Plinkert P, Lippert B, Feist K, Delank KW, Scheuermann K, Baier G, Ott I, Chenouda S, Becher H, Dietz A.

Oral Oncol. 2011 Dec;47(12):1154-8. doi: 10.1016/j.oraloncology.2011.08.003. Epub 2011 Aug 27.

PMID:
21873105
41.

Carbohydrate antigen 19-9 in saliva: possible preoperative marker of malignancy in parotid tumors.

Dyckhoff G, Warta R, Gonnermann A, Plinkert PK, Flechtenmacher C, Volkmann M.

Otolaryngol Head Neck Surg. 2011 Nov;145(5):772-7. doi: 10.1177/0194599811414512. Epub 2011 Jul 11.

PMID:
21746840
42.

Heparanase expression in head and neck squamous cell carcinomas is associated with reduced proliferation and improved survival.

Mogler C, Herold-Mende C, Dyckhoff G, Jenetzky E, Beckhove P, Helmke BM.

Histopathology. 2011 May;58(6):944-52. doi: 10.1111/j.1365-2559.2011.03834.x.

PMID:
21585429
43.

KRAS-mutation positive, metastatic tonsil carcinoma with cancer stem-like cell features and long-term response to gefitinib: a case report and review of the literature.

Gottschling S, Penzel R, Pelz T, Herpel E, Schnabel PA, Dyckhoff G, Thomas M, Kuhnt T.

J Clin Oncol. 2011 Jul 20;29(21):e616-9. doi: 10.1200/JCO.2011.34.5892. Epub 2011 May 9. Review. No abstract available.

PMID:
21555681
44.

Effects of tumour stage, comorbidity and therapy on survival of laryngeal cancer patients: a systematic review and a meta-analysis.

Rudolph E, Dyckhoff G, Becher H, Dietz A, Ramroth H.

Eur Arch Otorhinolaryngol. 2011 Feb;268(2):165-79. doi: 10.1007/s00405-010-1395-8. Epub 2010 Oct 19. Review.

PMID:
20957488
45.

Evaluation of drug transporters' significance for multidrug resistance in head and neck squamous cell carcinoma.

Theile D, Ketabi-Kiyanvash N, Herold-Mende C, Dyckhoff G, Efferth T, Bertholet V, Haefeli WE, Weiss J.

Head Neck. 2011 Jul;33(7):959-68. doi: 10.1002/hed.21559. Epub 2010 Aug 24.

PMID:
20737486
46.

Rapid T cell-based identification of human tumor tissue antigens by automated two-dimensional protein fractionation.

Beckhove P, Warta R, Lemke B, Stoycheva D, Momburg F, Schnölzer M, Warnken U, Schmitz-Winnenthal H, Ahmadi R, Dyckhoff G, Bucur M, Jünger S, Schueler T, Lennerz V, Woelfel T, Unterberg A, Herold-Mende C.

J Clin Invest. 2010 Jun;120(6):2230-42. doi: 10.1172/JCI37646. Epub 2010 May 10.

47.

Cytogenetic characterization of head and neck squamous cell carcinoma cell lines as model systems for the functional analyses of tumor-associated genes.

Freier K, Hofele C, Knoepfle K, Gross M, Devens F, Dyckhoff G, Plinkert P, Lichter P, Herold-Mende C.

J Oral Pathol Med. 2010 May;39(5):382-9. doi: 10.1111/j.1600-0714.2009.00864.x. Epub 2010 Feb 8.

PMID:
20149059
48.

Angiogenic growth factors in tissue homogenates of HNSCC: expression pattern, prognostic relevance, and interrelationships.

Montag M, Dyckhoff G, Lohr J, Helmke BM, Herrmann E, Plinkert PK, Herold-Mende C.

Cancer Sci. 2009 Jul;100(7):1210-8. doi: 10.1111/j.1349-7006.2009.01158.x. Epub 2009 Mar 31.

49.

Clinical predictors for germline mutations in head and neck paraganglioma patients: cost reduction strategy in genetic diagnostic process as fall-out.

Neumann HP, Erlic Z, Boedeker CC, Rybicki LA, Robledo M, Hermsen M, Schiavi F, Falcioni M, Kwok P, Bauters C, Lampe K, Fischer M, Edelman E, Benn DE, Robinson BG, Wiegand S, Rasp G, Stuck BA, Hoffmann MM, Sullivan M, Sevilla MA, Weiss MM, Peczkowska M, Kubaszek A, Pigny P, Ward RL, Learoyd D, Croxson M, Zabolotny D, Yaremchuk S, Draf W, Muresan M, Lorenz RR, Knipping S, Strohm M, Dyckhoff G, Matthias C, Reisch N, Preuss SF, Esser D, Walter MA, Kaftan H, Stöver T, Fottner C, Gorgulla H, Malekpour M, Zarandy MM, Schipper J, Brase C, Glien A, Kühnemund M, Koscielny S, Schwerdtfeger P, Välimäki M, Szyfter W, Finckh U, Zerres K, Cascon A, Opocher G, Ridder GJ, Januszewicz A, Suarez C, Eng C.

Cancer Res. 2009 Apr 15;69(8):3650-6. doi: 10.1158/0008-5472.CAN-08-4057. Epub 2009 Apr 7.

50.

Frequently methylated tumor suppressor genes in head and neck squamous cell carcinoma.

Bennett KL, Karpenko M, Lin MT, Claus R, Arab K, Dyckhoff G, Plinkert P, Herpel E, Smiraglia D, Plass C.

Cancer Res. 2008 Jun 15;68(12):4494-9. doi: 10.1158/0008-5472.CAN-07-6509.

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