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Items: 1 to 50 of 61

1.

Paging the Right Resident the First Time on General Internal Medicine: A Quality Improvement Project.

Carson J, Gottheil S, Dyck B, Rice T.

Jt Comm J Qual Patient Saf. 2019 Oct;45(10):711-716. doi: 10.1016/j.jcjq.2019.08.001. Epub 2019 Sep 5.

PMID:
31495578
2.

Use of incisional vacuum-assisted closure in the prevention of postoperative infection in high-risk patients who underwent spine surgery: a proof-of-concept study.

Dyck BA, Bailey CS, Steyn C, Petrakis J, Urquhart JC, Raj R, Rasoulinejad P.

J Neurosurg Spine. 2019 May 10;31(3):430-439. doi: 10.3171/2019.2.SPINE18947.

PMID:
31075767
3.

Phosphodiesterase 1b (PDE1B) Regulates Spatial and Contextual Memory in Hippocampus.

McQuown S, Xia S, Baumgärtel K, Barido R, Anderson G, Dyck B, Scott R, Peters M.

Front Mol Neurosci. 2019 Feb 7;12:21. doi: 10.3389/fnmol.2019.00021. eCollection 2019.

4.

Reduced expression of synapsin II in a chronic phencyclidine preclinical rat model of schizophrenia.

Thomson S, Dyck B, Daya R, Ho J, Bernardo A, Tian Y, Mishra RK.

Synapse. 2019 May;73(5):e22084. doi: 10.1002/syn.22084. Epub 2019 Jan 7.

PMID:
30582667
5.

Solvent-Controlled, Site-Selective N-Alkylation Reactions of Azolo-Fused Ring Heterocycles at N1-, N2-, and N3-Positions, Including Pyrazolo[3,4- d]pyrimidines, Purines, [1,2,3]Triazolo[4,5]pyridines, and Related Deaza-Compounds.

Bookser BC, Weinhouse MI, Burns AC, Valiere AN, Valdez LJ, Stanczak P, Na J, Rheingold AL, Moore CE, Dyck B.

J Org Chem. 2018 Jun 15;83(12):6334-6353. doi: 10.1021/acs.joc.8b00540. Epub 2018 Jun 6.

PMID:
29790748
6.

The divergent fates of primitive hydrospheric water on Earth and Mars.

Wade J, Dyck B, Palin RM, Moore JDP, Smye AJ.

Nature. 2017 Dec 20;552(7685):391-394. doi: 10.1038/nature25031.

PMID:
29293210
7.

Effects of canola meal source on the standardized ileal digestible amino acids and apparent metabolizable energy contents for broiler chickens.

Adewole DI, Rogiewicz A, Dyck B, Slominski BA.

Poult Sci. 2017 Dec 1;96(12):4298-4306. doi: 10.3382/ps/pex245.

8.

Standardized ileal digestible amino acid contents of canola meal from Canadian crushing plants for growing pigs.

Adewole DI, Rogiewicz A, Dyck B, Nyachoti CM, Slominski BA.

J Anim Sci. 2017 Jun;95(6):2670-2679. doi: 10.2527/jas.2017.1372.

PMID:
28727034
9.

Discovery of Selective Phosphodiesterase 1 Inhibitors with Memory Enhancing Properties.

Dyck B, Branstetter B, Gharbaoui T, Hudson AR, Breitenbucher JG, Gomez L, Botrous I, Marrone T, Barido R, Allerston CK, Cedervall EP, Xu R, Sridhar V, Barker R, Aertgeerts K, Schmelzer K, Neul D, Lee D, Massari ME, Andersen CB, Sebring K, Zhou X, Petroski R, Limberis J, Augustin M, Chun LE, Edwards TE, Peters M, Tabatabaei A.

J Med Chem. 2017 Apr 27;60(8):3472-3483. doi: 10.1021/acs.jmedchem.7b00302. Epub 2017 Apr 13.

PMID:
28406621
10.

Dynamics of three-dimensional telomere profiles of circulating tumor cells in patients with high-risk prostate cancer who are undergoing androgen deprivation and radiation therapies.

Wark L, Klonisch T, Awe J, LeClerc C, Dyck B, Quon H, Mai S.

Urol Oncol. 2017 Mar;35(3):112.e1-112.e11. doi: 10.1016/j.urolonc.2016.10.018. Epub 2016 Dec 10.

11.

Associations between patient expectations of joint arthroplasty surgery and pre- and post-operative clinical status.

Dyck BA, Zywiel MG, Mahomed A, Gandhi R, Perruccio AV, Mahomed NN.

Expert Rev Med Devices. 2014 Jul;11(4):403-15. doi: 10.1586/17434440.2014.916208. Epub 2014 May 3. Review.

PMID:
24793876
12.

Synapsin II gene expression in the dorsolateral prefrontal cortex of brain specimens from patients with schizophrenia and bipolar disorder: effect of lifetime intake of antipsychotic drugs.

Tan ML, Dyck BA, Gabriele J, Daya RP, Thomas N, Sookram C, Basu D, Ferro MA, Chong VZ, Mishra RK.

Pharmacogenomics J. 2014 Feb;14(1):63-9. doi: 10.1038/tpj.2013.6. Epub 2013 Mar 26.

13.

PAOPA, a potent dopamine D2 receptor allosteric modulator, prevents and reverses behavioral and biochemical abnormalities in an amphetamine-sensitized preclinical animal model of schizophrenia.

Beyaert MG, Daya RP, Dyck BA, Johnson RL, Mishra RK.

Eur Neuropsychopharmacol. 2013 Mar;23(3):253-62. doi: 10.1016/j.euroneuro.2012.04.010. Epub 2012 May 30.

PMID:
22658400
14.

Behavioral effects of non-viral mediated RNA interference of synapsin II in the medial prefrontal cortex of the rat.

Dyck BA, Tan ML, Daya RP, Basu D, Sookram CD, Thomas N, Mishra RK.

Schizophr Res. 2012 May;137(1-3):32-8. doi: 10.1016/j.schres.2012.01.029. Epub 2012 Feb 17.

PMID:
22341900
15.

Starch source and content in postpartum dairy cow diets: effects on plasma metabolites and reproductive processes.

Dyck BL, Colazo MG, Ambrose DJ, Dyck MK, Doepel L.

J Dairy Sci. 2011 Sep;94(9):4636-46. doi: 10.3168/jds.2010-4056.

16.

Medial prefrontal cortical synapsin II knock-down induces behavioral abnormalities in the rat: examining synapsin II in the pathophysiology of schizophrenia.

Dyck BA, Beyaert MG, Ferro MA, Mishra RK.

Schizophr Res. 2011 Aug;130(1-3):250-9. doi: 10.1016/j.schres.2011.05.017.

PMID:
21689907
18.

Atypical antipsychotic drugs upregulate synapsin II in the prefrontal cortex of post-mortem samples obtained from patients with schizophrenia.

Guest KA, Dyck BA, Shethwala S, Mishra RK.

Schizophr Res. 2010 Jul;120(1-3):229-31. doi: 10.1016/j.schres.2010.03.029. No abstract available.

PMID:
20434888
19.

Role of AP-2alpha transcription factor in the regulation of synapsin II gene expression by dopamine D1 and D2 receptors.

Skoblenick KJ, Argintaru N, Xu Y, Dyck BA, Basu D, Tan ML, Mazurek MF, Mishra RK.

J Mol Neurosci. 2010 Jun;41(2):267-77. doi: 10.1007/s12031-009-9299-z. Epub 2009 Oct 20.

PMID:
19842069
20.

Prevention and control of infections in the home.

Embil JM, Dyck B, Plourde P.

CMAJ. 2009 May 26;180(11):E82-6. doi: 10.1503/cmaj.071898. Review. No abstract available.

21.

Behavioral abnormalities in synapsin II knockout mice implicate a causal factor in schizophrenia.

Dyck BA, Skoblenick KJ, Castellano JM, Ki K, Thomas N, Mishra RK.

Synapse. 2009 Aug;63(8):662-72. doi: 10.1002/syn.20643.

PMID:
19360855
22.

Characterization of thien-2-yl 1S,2R-milnacipran analogues as potent norepinephrine/serotonin transporter inhibitors for the treatment of neuropathic pain.

Dyck B, Tamiya J, Jovic F, Pick RR, Bradbury MJ, O'Brien J, Wen J, Johns M, Madan A, Fleck BA, Foster AC, Li B, Zhang M, Tran JA, Vickers T, Grey J, Saunders J, Chen C.

J Med Chem. 2008 Nov 27;51(22):7265-72. doi: 10.1021/jm8009537.

PMID:
18954038
23.

Studies on the structure-activity relationship of bicifadine analogs as monoamine transporter inhibitors.

Zhang M, Jovic F, Vickers T, Dyck B, Tamiya J, Grey J, Tran JA, Fleck BA, Pick R, Foster AC, Chen C.

Bioorg Med Chem Lett. 2008 Jul 1;18(13):3682-6. doi: 10.1016/j.bmcl.2008.05.077. Epub 2008 May 23.

PMID:
18539031
24.

Studies on a series of milnacipran analogs containing a heteroaromatic group as potent norepinephrine and serotonin transporter inhibitors.

Vickers T, Dyck B, Tamiya J, Zhang M, Jovic F, Grey J, Fleck BA, Aparicio A, Johns M, Jin L, Tang H, Foster AC, Chen C.

Bioorg Med Chem Lett. 2008 Jun 1;18(11):3230-5. doi: 10.1016/j.bmcl.2008.04.045. Epub 2008 Apr 25.

PMID:
18468895
25.

Identification of 1S,2R-milnacipran analogs as potent norepinephrine and serotonin transporter inhibitors.

Tamiya J, Dyck B, Zhang M, Phan K, Fleck BA, Aparicio A, Jovic F, Tran JA, Vickers T, Grey J, Foster AC, Chen C.

Bioorg Med Chem Lett. 2008 Jun 1;18(11):3328-32. doi: 10.1016/j.bmcl.2008.04.025. Epub 2008 Apr 15.

PMID:
18445525
26.

HPA axis.

Dyck B.

Curr Top Med Chem. 2008;8(6):505. No abstract available.

PMID:
18397175
27.

Studies on the SAR and pharmacophore of milnacipran derivatives as monoamine transporter inhibitors.

Chen C, Dyck B, Fleck BA, Foster AC, Grey J, Jovic F, Mesleh M, Phan K, Tamiya J, Vickers T, Zhang M.

Bioorg Med Chem Lett. 2008 Feb 15;18(4):1346-9. doi: 10.1016/j.bmcl.2008.01.011. Epub 2008 Jan 9.

PMID:
18207394
28.

Synapsin II knockout mice show sensorimotor gating and behavioural abnormalities similar to those in the phencyclidine-induced preclinical animal model of schizophrenia.

Dyck BA, Skoblenick KJ, Castellano JM, Ki K, Thomas N, Mishra RK.

Schizophr Res. 2007 Dec;97(1-3):292-3. Epub 2007 Sep 27. No abstract available.

PMID:
17900867
29.

Synthesis and structure-activity relationships of spirohydantoin-derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1).

Rowbottom MW, Vickers TD, Tamiya J, Zhang M, Dyck B, Grey J, Schwarz D, Heise CE, Hedrick M, Wen J, Tang H, Wang H, Fisher A, Aparicio A, Saunders J, Goodfellow VS.

Bioorg Med Chem Lett. 2007 Apr 15;17(8):2171-8. Epub 2007 Feb 4.

PMID:
17350839
30.

Thienopyrimidinone bis-aminopyrrolidine ureas as potent melanin-concentrating hormone receptor-1 (MCH-R1) antagonists.

Zhang M, Tamiya J, Nguyen L, Rowbottom MW, Dyck B, Vickers TD, Grey J, Schwarz DA, Heise CE, Haelewyn J, Mistry MS, Goodfellow VS.

Bioorg Med Chem Lett. 2007 May 1;17(9):2535-9. Epub 2007 Feb 8.

PMID:
17329101
31.

Synthesis and structure-activity relationships of retro bis-aminopyrrolidine urea (rAPU) derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1). Part 1.

Rowbottom MW, Vickers TD, Dyck B, Grey J, Tamiya J, Zhang M, Kiankarimi M, Wu D, Dwight W, Wade WS, Schwarz D, Heise CE, Madan A, Fisher A, Petroski R, Goodfellow VS.

Bioorg Med Chem Lett. 2006 Sep 1;16(17):4450-7. Epub 2006 Jun 30.

PMID:
16814542
32.

A thienopyridazinone-based melanin-concentrating hormone receptor 1 antagonist with potent in vivo anorectic properties.

Dyck B, Markison S, Zhao L, Tamiya J, Grey J, Rowbottom MW, Zhang M, Vickers T, Sorensen K, Norton C, Wen J, Heise CE, Saunders J, Conlon P, Madan A, Schwarz D, Goodfellow VS.

J Med Chem. 2006 Jun 29;49(13):3753-6.

PMID:
16789729
33.

Substituted chromones and quinolones as potent melanin-concentrating hormone receptor 1 antagonists.

Dyck B, Zhao L, Tamiya J, Pontillo J, Hudson S, Ching B, Heise CE, Wen J, Norton C, Madan A, Schwarz D, Wade W, Goodfellow VS.

Bioorg Med Chem Lett. 2006 Aug 15;16(16):4237-42. Epub 2006 Jun 12.

PMID:
16762549
34.

Translocation of AIF in the human and rat striatum following protracted haloperidol, but not clozapine treatment.

Skoblenick KJ, Castellano JM, Rogoza RM, Dyck BA, Thomas N, Gabriele JP, Chong VZ, Mishra RK.

Apoptosis. 2006 May;11(5):663-72.

PMID:
16528470
35.

cDNA array reveals increased expression of glucose-dependent insulinotropic polypeptide following chronic clozapine treatment: role in atypical antipsychotic drug-induced adverse metabolic effects.

Sondhi S, Castellano JM, Chong VZ, Rogoza RM, Skoblenick KJ, Dyck BA, Gabriele J, Thomas N, Ki K, Pristupa ZB, Singh AN, MacCrimmon D, Voruganti P, Foster J, Mishra RK.

Pharmacogenomics J. 2006 Mar-Apr;6(2):131-40.

PMID:
16402076
36.

Design and synthesis of tricyclic corticotropin-releasing factor-1 antagonists.

Gross RS, Guo Z, Dyck B, Coon T, Huang CQ, Lowe RF, Marinkovic D, Moorjani M, Nelson J, Zamani-Kord S, Grigoriadis DE, Hoare SR, Crowe PD, Bu JH, Haddach M, McCarthy J, Saunders J, Sullivan R, Chen T, Williams JP.

J Med Chem. 2005 Sep 8;48(18):5780-93.

PMID:
16134945
37.

Potent and orally active non-peptide antagonists of the human melanocortin-4 receptor based on a series of trans-2-disubstituted cyclohexylpiperazines.

Tucci FC, White NS, Markison S, Joppa M, Tran JA, Fleck BA, Madan A, Dyck BP, Parker J, Pontillo J, Arellano LM, Marinkovic D, Jiang W, Chen CW, Gogas KR, Goodfellow VS, Saunders J, Foster AC, Chen C.

Bioorg Med Chem Lett. 2005 Oct 1;15(19):4389-95.

PMID:
16098742
38.

Design and synthesis of tricyclic imidazo[4,5-b]pyridin-2-ones as corticotropin-releasing factor-1 antagonists.

Guo Z, Tellew JE, Gross RS, Dyck B, Grey J, Haddach M, Kiankarimi M, Lanier M, Li BF, Luo Z, McCarthy JR, Moorjani M, Saunders J, Sullivan R, Zhang X, Zamani-Kord S, Grigoriadis DE, Crowe PD, Chen TK, Williams JP.

J Med Chem. 2005 Aug 11;48(16):5104-7.

PMID:
16078829
39.

Synthesis and structure-activity relationships of biarylcarboxamide bis-aminopyrrolidine urea derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1).

Rowbottom MW, Vickers TD, Dyck B, Tamiya J, Zhang M, Zhao L, Grey J, Provencal D, Schwarz D, Heise CE, Mistry M, Fisher A, Dong T, Hu T, Saunders J, Goodfellow VS.

Bioorg Med Chem Lett. 2005 Jul 15;15(14):3439-45.

PMID:
15950467
40.

Potent, orally active corticotropin-releasing factor receptor-1 antagonists containing a tricyclic pyrrolopyridine or pyrazolopyridine core.

Dyck B, Grigoriadis DE, Gross RS, Guo Z, Haddach M, Marinkovic D, McCarthy JR, Moorjani M, Regan CF, Saunders J, Schwaebe MK, Szabo T, Williams JP, Zhang X, Bozigian H, Chen TK.

J Med Chem. 2005 Jun 16;48(12):4100-10.

PMID:
15943483
41.

Bis(aminopyrrolidine)-derived ureas (APUs) as potent MCH1 receptor antagonists.

Grey J, Dyck B, Rowbottom MW, Tamiya J, Vickers TD, Zhang M, Zhao L, Heise CE, Schwarz D, Saunders J, Goodfellow VS.

Bioorg Med Chem Lett. 2005 Feb 15;15(4):999-1004.

PMID:
15686900
42.

Potent imidazole and triazole CB1 receptor antagonists related to SR141716.

Dyck B, Goodfellow VS, Phillips T, Grey J, Haddach M, Rowbottom M, Naeve GS, Brown B, Saunders J.

Bioorg Med Chem Lett. 2004 Mar 8;14(5):1151-4.

PMID:
14980654
43.

Aryl piperazine melanocortin MC4 receptor agonists.

Dyck B, Parker J, Phillips T, Carter L, Murphy B, Summers R, Hermann J, Baker T, Cismowski M, Saunders J, Goodfellow V.

Bioorg Med Chem Lett. 2003 Nov 3;13(21):3793-6.

PMID:
14552781
44.

Bed utilization of patients with methicillin-resistant Staphylococcus aureus in a Canadian tertiary-care center.

Cooper CL, Dyck B, Ormiston D, Olekson K, McLeod J, Nicolle LE, Embil JM.

Infect Control Hosp Epidemiol. 2002 Sep;23(9):483-4. No abstract available.

PMID:
12269441
45.

Total asymmetric synthesis of the putative structure of the cytotoxic diterpenoid (-)-sclerophytin a and of the authentic natural sclerophytins A and B.

Bernardelli P, Moradei OM, Friedrich D, Yang J, Gallou F, Dyck BP, Doskotch RW, Lange T, Paquette LA.

J Am Chem Soc. 2001 Sep 19;123(37):9021-32.

PMID:
11552810
46.

Characterization of a toxin A-negative, toxin B-positive strain of Clostridium difficile responsible for a nosocomial outbreak of Clostridium difficile-associated diarrhea.

Alfa MJ, Kabani A, Lyerly D, Moncrief S, Neville LM, Al-Barrak A, Harding GK, Dyck B, Olekson K, Embil JM.

J Clin Microbiol. 2000 Jul;38(7):2706-14.

47.

[Stanford University Hospital diabetes program].

Dyck BA.

Kango Kenkyu. 1998 Jan-Feb;31(1):13-22. Japanese. No abstract available.

PMID:
10437455
48.

An outbreak of toxin A negative, toxin B positive Clostridium difficile-associated diarrhea in a Canadian tertiary-care hospital.

al-Barrak A, Embil J, Dyck B, Olekson K, Nicoll D, Alfa M, Kabani A.

Can Commun Dis Rep. 1999 Apr 1;25(7):65-9. English, French. No abstract available.

49.

Regional dissemination and control of epidemic methicillin-resistant Staphylococcus aureus. Manitoba Chapter of CHICA-Canada.

Nicolle LE, Dyck B, Thompson G, Roman S, Kabani A, Plourde P, Fast M, Embil J.

Infect Control Hosp Epidemiol. 1999 Mar;20(3):202-5.

PMID:
10100549
50.

Diabetes update with a cardiac perspective.

Dyck B.

Prog Cardiovasc Nurs. 1998 Spring;13(2):28-31, 36. Review.

PMID:
9802114

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