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Items: 16


Early life selective knockdown of the TrkB receptor and maternal separation modulates adult stress phenotype.

Prowse N, Dwyer Z, Thompson A, Fortin T, Elson K, Robeson H, Fenner B, Hayley S.

Behav Brain Res. 2019 Sep 27;378:112260. doi: 10.1016/j.bbr.2019.112260. [Epub ahead of print]


Chronic unpredictable stress influenced the behavioral but not the neurodegenerative impact of paraquat.

Rudyk C, Dwyer Z, McNeill J, Salmaso N, Farmer K, Prowse N, Hayley S.

Neurobiol Stress. 2019 May 31;11:100179. doi: 10.1016/j.ynstr.2019.100179. eCollection 2019 Nov.


Leucine-rich repeat kinase-2 (LRRK2) modulates paraquat-induced inflammatory sickness and stress phenotype.

Rudyk C, Dwyer Z, Hayley S; CLINT membership.

J Neuroinflammation. 2019 Jun 7;16(1):120. doi: 10.1186/s12974-019-1483-7.


Multiplexed primer extension sequencing: A targeted RNA-seq method that enables high-precision quantitation of mRNA splicing isoforms and rare pre-mRNA splicing intermediates.

Gildea MA, Dwyer ZW, Pleiss JA.

Methods. 2019 May 21. pii: S1046-2023(18)30383-9. doi: 10.1016/j.ymeth.2019.05.013. [Epub ahead of print]


Detection of splice isoforms and rare intermediates using multiplexed primer extension sequencing.

Xu H, Fair BJ, Dwyer ZW, Gildea M, Pleiss JA.

Nat Methods. 2019 Jan;16(1):55-58. doi: 10.1038/s41592-018-0258-x. Epub 2018 Dec 20.


Perinatal antibiotic exposure alters composition of murine gut microbiota and may influence later responses to peanut antigen.

Boutin RCT, Dwyer Z, Farmer K, Rudyk C, Forbes MR, Hayley S.

Allergy Asthma Clin Immunol. 2018 Nov 1;14:42. doi: 10.1186/s13223-018-0263-8. eCollection 2018.


In Vivo Use of a Multi-DNA Aptamer-Based Payload/Targeting System To Study Dopamine Dysregulation in the Central Nervous System.

McConnell EM, Ventura K, Dwyer Z, Hunt V, Koudrina A, Holahan MR, DeRosa MC.

ACS Chem Neurosci. 2019 Jan 16;10(1):371-383. doi: 10.1021/acschemneuro.8b00292. Epub 2018 Sep 17.


The impact of murine LRRK2 G2019S transgene overexpression on acute responses to inflammatory challenge.

Litteljohn D, Rudyk C, Dwyer Z, Farmer K, Fortin T, Hayley S; Canadian Lrrk2 in Inflammation Team (CLINT).

Brain Behav Immun. 2018 Jan;67:246-256. doi: 10.1016/j.bbi.2017.09.002. Epub 2017 Sep 8.


Age and Chronicity of Administration Dramatically Influenced the Impact of Low Dose Paraquat Exposure on Behavior and Hypothalamic-Pituitary-Adrenal Activity.

Rudyk CA, McNeill J, Prowse N, Dwyer Z, Farmer K, Litteljohn D, Caldwell W, Hayley S.

Front Aging Neurosci. 2017 Jul 14;9:222. doi: 10.3389/fnagi.2017.00222. eCollection 2017.


Individual and interactive sex-specific effects of acute restraint and systemic IFN-γ treatment on neurochemistry.

Litteljohn D, Rudyk C, Razmjou S, Dwyer Z, Syed S, Hayley S.

Neurochem Int. 2017 Jan;102:95-104. doi: 10.1016/j.neuint.2016.11.005. Epub 2016 Nov 19.


Ketamine modulates hippocampal neurogenesis and pro-inflammatory cytokines but not stressor induced neurochemical changes.

Clarke M, Razmjou S, Prowse N, Dwyer Z, Litteljohn D, Pentz R, Anisman H, Hayley S.

Neuropharmacology. 2017 Jan;112(Pt A):210-220. doi: 10.1016/j.neuropharm.2016.04.021. Epub 2016 Apr 20.


The interactive effects of ketamine and magnesium upon depressive-like pathology.

Razmjou S, Litteljohn D, Rudyk C, Syed S, Clarke M, Pentz R, Dwyer Z, Hayley S.

Neuropsychiatr Dis Treat. 2016 Sep 8;12:2049-56. doi: 10.2147/NDT.S111131. eCollection 2016.


Interactive effects of ghrelin and ketamine on forced swim performance: Implications for novel antidepressant strategies.

Landrigan J, Shawaf F, Dwyer Z, Abizaid A, Hayley S.

Neurosci Lett. 2018 Mar 16;669:55-58. doi: 10.1016/j.neulet.2016.08.015. Epub 2016 Aug 11.


Paraquat and psychological stressor interactions as pertains to Parkinsonian co-morbidity.

Rudyk C, Litteljohn D, Syed S, Dwyer Z, Hayley S.

Neurobiol Stress. 2015 Nov 12;2:85-93. doi: 10.1016/j.ynstr.2015.09.001. eCollection 2015.


SAICAR induces protein kinase activity of PKM2 that is necessary for sustained proliferative signaling of cancer cells.

Keller KE, Doctor ZM, Dwyer ZW, Lee YS.

Mol Cell. 2014 Mar 6;53(5):700-9. doi: 10.1016/j.molcel.2014.02.015.


The intestinal fatty acid propionate inhibits Salmonella invasion through the post-translational control of HilD.

Hung CC, Garner CD, Slauch JM, Dwyer ZW, Lawhon SD, Frye JG, McClelland M, Ahmer BM, Altier C.

Mol Microbiol. 2013 Mar;87(5):1045-60. doi: 10.1111/mmi.12149. Epub 2013 Jan 28.

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