Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 150

1.

Increased formation of reactive oxygen species during tumor growth: Ex vivo low-temperature EPR and in vivo bioluminescence analyses.

Cheng G, Pan J, Podsiadly R, Zielonka J, Garces AM, Dias Duarte Machado LG, Bennett B, McAllister D, Dwinell MB, You M, Kalyanaraman B.

Free Radic Biol Med. 2020 Feb 1;147:167-174. doi: 10.1016/j.freeradbiomed.2019.12.020. Epub 2019 Dec 23.

PMID:
31874251
2.

The Year of the Rat: The Rat Genome Database at 20: a multi-species knowledgebase and analysis platform.

Smith JR, Hayman GT, Wang SJ, Laulederkind SJF, Hoffman MJ, Kaldunski ML, Tutaj M, Thota J, Nalabolu HS, Ellanki SLR, Tutaj MA, De Pons JL, Kwitek AE, Dwinell MR, Shimoyama ME.

Nucleic Acids Res. 2020 Jan 8;48(D1):D731-D742. doi: 10.1093/nar/gkz1041.

PMID:
31713623
3.

Precision Medicine and Precision Public Health: Academic Education and Community Engagement.

Meurer JR, Whittle JC, Lamb KM, Kosasih MA, Dwinell MR, Urrutia RA.

Am J Prev Med. 2019 Aug;57(2):286-289. doi: 10.1016/j.amepre.2019.03.010. No abstract available.

PMID:
31326012
4.

Rat Genome Databases, Repositories, and Tools.

Laulederkind SJF, Hayman GT, Wang SJ, Hoffman MJ, Smith JR, Bolton ER, De Pons J, Tutaj MA, Tutaj M, Thota J, Dwinell MR, Shimoyama M.

Methods Mol Biol. 2019;2018:71-96. doi: 10.1007/978-1-4939-9581-3_3.

PMID:
31228152
5.

The Rat: A Model Used in Biomedical Research.

Smith JR, Bolton ER, Dwinell MR.

Methods Mol Biol. 2019;2018:1-41. doi: 10.1007/978-1-4939-9581-3_1.

PMID:
31228150
6.

Synergistic inhibition of tumor cell proliferation by metformin and mito-metformin in the presence of iron chelators.

Cheng G, Zielonka J, Hardy M, Ouari O, Chitambar CR, Dwinell MB, Kalyanaraman B.

Oncotarget. 2019 May 28;10(37):3518-3532. doi: 10.18632/oncotarget.26943. eCollection 2019 May 28.

7.

STING agonist inflames the pancreatic cancer immune microenvironment and reduces tumor burden in mouse models.

Jing W, McAllister D, Vonderhaar EP, Palen K, Riese MJ, Gershan J, Johnson BD, Dwinell MB.

J Immunother Cancer. 2019 Apr 29;7(1):115. doi: 10.1186/s40425-019-0573-5.

8.

Quantitative phenotype analysis to identify, validate and compare rat disease models.

Zhao Y, Smith JR, Wang SJ, Dwinell MR, Shimoyama M.

Database (Oxford). 2019 Jan 1;2019. pii: baz037. doi: 10.1093/database/baz037.

9.

Identification of a Rat Mammary Tumor Risk Locus That Is Syntenic with the Commonly Amplified 8q12.1 and 8q22.1 Regions in Human Breast Cancer Patients.

Plasterer C, Tsaih SW, Lemke A, Schilling R, Dwinell M, Rau A, Auer P, Rui H, Flister MJ.

G3 (Bethesda). 2019 May 7;9(5):1739-1743. doi: 10.1534/g3.118.200873.

10.

Integrated curation and data mining for disease and phenotype models at the Rat Genome Database.

Wang SJ, Laulederkind SJF, Zhao Y, Hayman GT, Smith JR, Tutaj M, Thota J, Tutaj MA, Hoffman MJ, Bolton ER, De Pons J, Dwinell MR, Shimoyama M.

Database (Oxford). 2019 Jan 1;2019. doi: 10.1093/database/baz014.

11.

A Serum-Induced Transcriptome and Serum Cytokine Signature Obtained at Diagnosis Correlates with the Development of Early Pancreatic Ductal Adenocarcinoma Metastasis.

Tsai S, McOlash L, Jia S, Zhang J, Simpson P, Kaldunski ML, Aldakkak M, Grewal J, Palen K, Dwinell MB, Johnson BD, Mackinnon A, Hessner MJ, Gershan JA.

Cancer Epidemiol Biomarkers Prev. 2019 Apr;28(4):680-689. doi: 10.1158/1055-9965.EPI-18-0813. Epub 2018 Dec 7.

PMID:
30530849
12.

Mitochondria-targeted drugs stimulate mitophagy and abrogate colon cancer cell proliferation.

Boyle KA, Van Wickle J, Hill RB, Marchese A, Kalyanaraman B, Dwinell MB.

J Biol Chem. 2018 Sep 21;293(38):14891-14904. doi: 10.1074/jbc.RA117.001469. Epub 2018 Aug 7.

13.

Diacylglycerol kinase ζ (DGKζ) and Casitas b-lineage proto-oncogene b-deficient mice have similar functional outcomes in T cells but DGKζ-deficient mice have increased T cell activation and tumor clearance.

Wesley EM, Xin G, McAllister D, Malarkannan S, Newman DK, Dwinell MB, Cui W, Johnson BD, Riese MJ.

Immunohorizons. 2018 Apr 1;2(4):107-118. doi: 10.4049/immunohorizons.1700055.

14.

Sdha+/- Rats Display Minimal Muscle Pathology Without Significant Behavioral or Biochemical Abnormalities.

Siebers EM, Choi MJ, Tinklenberg JA, Beatka MJ, Ayres S, Meng H, Helbling DC, Takizawa A, Bennett B, Garces AM, Dias Duarte Machado LG, Dimmock D, Dwinell MR, Geurts AM, Lawlor MW.

J Neuropathol Exp Neurol. 2018 Aug 1;77(8):665-672. doi: 10.1093/jnen/nly042.

15.

A Primer for the Rat Genome Database (RGD).

Laulederkind SJF, Hayman GT, Wang SJ, Smith JR, Petri V, Hoffman MJ, De Pons J, Tutaj MA, Ghiasvand O, Tutaj M, Thota J, Dwinell MR, Shimoyama M.

Methods Mol Biol. 2018;1757:163-209. doi: 10.1007/978-1-4939-7737-6_8.

16.

GEMMs Are a Gem When it Comes to Defining the Role of HIF2α in Mucinous Cystic Neoplasms.

Boyle KA, Dwinell MB.

Cell Mol Gastroenterol Hepatol. 2017 Dec 8;5(2):165-166. doi: 10.1016/j.jcmgh.2017.11.008. eCollection 2018. No abstract available.

17.

Development of primary human pancreatic cancer organoids, matched stromal and immune cells and 3D tumor microenvironment models.

Tsai S, McOlash L, Palen K, Johnson B, Duris C, Yang Q, Dwinell MB, Hunt B, Evans DB, Gershan J, James MA.

BMC Cancer. 2018 Mar 27;18(1):335. doi: 10.1186/s12885-018-4238-4.

18.

Corrigendum to 'A review of the basics of mitochondrial bioenergetics, metabolism, and related signaling pathways in cancer cells: Therapeutic targeting of tumor mitochondria with lipophilic cationic compounds' [REDOX 14C (2017) 316-327].

Kalyanaraman B, Cheng G, Hardy M, Ouari O, Lopez M, Joseph J, Zielonka J, Dwinell MB.

Redox Biol. 2018 Jun;16:426-427. doi: 10.1016/j.redox.2018.03.001. Epub 2018 Mar 13. No abstract available.

19.

A review of the basics of mitochondrial bioenergetics, metabolism, and related signaling pathways in cancer cells: Therapeutic targeting of tumor mitochondria with lipophilic cationic compounds.

Kalyanaraman B, Cheng G, Hardy M, Ouari O, Lopez M, Joseph J, Zielonka J, Dwinell MB.

Redox Biol. 2018 Apr;14:316-327. doi: 10.1016/j.redox.2017.09.020. Epub 2017 Sep 29. Review. Erratum in: Redox Biol. 2018 Mar 13;:.

20.

Differences in Sulfotyrosine Binding amongst CXCR1 and CXCR2 Chemokine Ligands.

Moussouras NA, Getschman AE, Lackner ER, Veldkamp CT, Dwinell MB, Volkman BF.

Int J Mol Sci. 2017 Sep 3;18(9). pii: E1894. doi: 10.3390/ijms18091894.

21.

CCR7 Sulfotyrosine Enhances CCL21 Binding.

Phillips AJ, Taleski D, Koplinski CA, Getschman AE, Moussouras NA, Richard AM, Peterson FC, Dwinell MB, Volkman BF, Payne RJ, Veldkamp CT.

Int J Mol Sci. 2017 Aug 25;18(9). pii: E1857. doi: 10.3390/ijms18091857.

22.

Rat Genome and Model Resources.

Shimoyama M, Smith JR, Bryda E, Kuramoto T, Saba L, Dwinell M.

ILAR J. 2017 Jul 1;58(1):42-58. doi: 10.1093/ilar/ilw041. Review.

23.

Haploid embryonic stem cell lines derived from androgenetic and parthenogenetic rat blastocysts.

Hirabayashi M, Hara H, Goto T, Takizawa A, Dwinell MR, Yamanaka T, Hochi S, Nakauchi H.

J Reprod Dev. 2017 Dec 15;63(6):611-616. doi: 10.1262/jrd.2017-074. Epub 2017 Aug 19.

24.

Host genetic modifiers of nonproductive angiogenesis inhibit breast cancer.

Flister MJ, Tsaih SW, Stoddard A, Plasterer C, Jagtap J, Parchur AK, Sharma G, Prisco AR, Lemke A, Murphy D, Al-Gizawiy M, Straza M, Ran S, Geurts AM, Dwinell MR, Greene AS, Bergom C, LaViolette PS, Joshi A.

Breast Cancer Res Treat. 2017 Aug;165(1):53-64. doi: 10.1007/s10549-017-4311-8. Epub 2017 May 31.

25.

Modified Metformin as a More Potent Anticancer Drug: Mitochondrial Inhibition, Redox Signaling, Antiproliferative Effects and Future EPR Studies.

Kalyanaraman B, Cheng G, Hardy M, Ouari O, Sikora A, Zielonka J, Dwinell MB.

Cell Biochem Biophys. 2017 Dec;75(3-4):311-317. doi: 10.1007/s12013-017-0796-3. Epub 2017 Apr 21.

26.

Mitochondria-targeted metformins: anti-tumour and redox signalling mechanisms.

Kalyanaraman B, Cheng G, Hardy M, Ouari O, Sikora A, Zielonka J, Dwinell M.

Interface Focus. 2017 Apr 6;7(2):20160109. doi: 10.1098/rsfs.2016.0109. Review.

27.

Structural basis for chemokine recognition by a G protein-coupled receptor and implications for receptor activation.

Ziarek JJ, Kleist AB, London N, Raveh B, Montpas N, Bonneterre J, St-Onge G, DiCosmo-Ponticello CJ, Koplinski CA, Roy I, Stephens B, Thelen S, Veldkamp CT, Coffman FD, Cohen MC, Dwinell MB, Thelen M, Peterson FC, Heveker N, Volkman BF.

Sci Signal. 2017 Mar 21;10(471). pii: eaah5756. doi: 10.1126/scisignal.aah5756.

28.

Lung injury pathways: Adenosine receptor 2B signaling limits development of ischemic bronchiolitis obliterans organizing pneumonia.

Densmore JC, Schaid TR, Jeziorczak PM, Medhora M, Audi S, Nayak S, Auchampach J, Dwinell MR, Geurts AM, Jacobs ER.

Exp Lung Res. 2017 Feb;43(1):38-48. doi: 10.1080/01902148.2017.1286697. Epub 2017 Mar 7.

29.

Cancer cell chemokines direct chemotaxis of activated stellate cells in pancreatic ductal adenocarcinoma.

Roy I, Boyle KA, Vonderhaar EP, Zimmerman NP, Gorse E, Mackinnon AC, Hwang RF, Franco-Barraza J, Cukierman E, Tsai S, Evans DB, Dwinell MB.

Lab Invest. 2017 Mar;97(3):302-317. doi: 10.1038/labinvest.2016.146. Epub 2017 Jan 16.

30.

Exploring human disease using the Rat Genome Database.

Shimoyama M, Laulederkind SJ, De Pons J, Nigam R, Smith JR, Tutaj M, Petri V, Hayman GT, Wang SJ, Ghiasvand O, Thota J, Dwinell MR.

Dis Model Mech. 2016 Oct 1;9(10):1089-1095. Review.

31.

Exploiting agonist biased signaling of chemokines to target cancer.

Roy I, Getschman AE, Volkman BF, Dwinell MB.

Mol Carcinog. 2017 Mar;56(3):804-813. doi: 10.1002/mc.22571. Epub 2016 Oct 4.

32.

Disease, Models, Variants and Altered Pathways-Journeying RGD Through the Magnifying Glass.

Petri V, Hayman GT, Tutaj M, Smith JR, Laulederkind S, Wang SJ, Nigam R, De Pons J, Shimoyama M, Dwinell MR.

Comput Struct Biotechnol J. 2015 Nov 26;14:35-48. doi: 10.1016/j.csbj.2015.11.006. eCollection 2016.

33.

Comprehensive coverage of cardiovascular disease data in the disease portals at the Rat Genome Database.

Wang SJ, Laulederkind SJ, Hayman GT, Petri V, Smith JR, Tutaj M, Nigam R, Dwinell MR, Shimoyama M.

Physiol Genomics. 2016 Aug 1;48(8):589-600. doi: 10.1152/physiolgenomics.00046.2016. Epub 2016 Jun 10.

34.

E-cadherin re-expression shows in vivo evidence for mesenchymal to epithelial transition in clonal metastatic breast tumor cells.

Palen K, Weber J, Dwinell MB, Johnson BD, Ramchandran R, Gershan JA.

Oncotarget. 2016 Jul 12;7(28):43363-43375. doi: 10.18632/oncotarget.9715.

35.

Mitochondria-Targeted Analogues of Metformin Exhibit Enhanced Antiproliferative and Radiosensitizing Effects in Pancreatic Cancer Cells.

Cheng G, Zielonka J, Ouari O, Lopez M, McAllister D, Boyle K, Barrios CS, Weber JJ, Johnson BD, Hardy M, Dwinell MB, Kalyanaraman B.

Cancer Res. 2016 Jul 1;76(13):3904-15. doi: 10.1158/0008-5472.CAN-15-2534. Epub 2016 May 23.

36.

The Disease Portals, disease-gene annotation and the RGD disease ontology at the Rat Genome Database.

Hayman GT, Laulederkind SJ, Smith JR, Wang SJ, Petri V, Nigam R, Tutaj M, De Pons J, Dwinell MR, Shimoyama M.

Database (Oxford). 2016 Mar 23;2016. pii: baw034. doi: 10.1093/database/baw034. Print 2016.

37.

Report of the National Heart, Lung, and Blood Institute Working Group on Sex Differences Research in Cardiovascular Disease: Scientific Questions and Challenges.

Maric-Bilkan C, Arnold AP, Taylor DA, Dwinell M, Howlett SE, Wenger N, Reckelhoff JF, Sandberg K, Churchill G, Levin E, Lundberg MS.

Hypertension. 2016 May;67(5):802-7. doi: 10.1161/HYPERTENSIONAHA.115.06967. Epub 2016 Mar 14. Review. No abstract available.

38.

Ndufc2 Gene Inhibition Is Associated With Mitochondrial Dysfunction and Increased Stroke Susceptibility in an Animal Model of Complex Human Disease.

Rubattu S, Di Castro S, Schulz H, Geurts AM, Cotugno M, Bianchi F, Maatz H, Hummel O, Falak S, Stanzione R, Marchitti S, Scarpino S, Giusti B, Kura A, Gensini GF, Peyvandi F, Mannucci PM, Rasura M, Sciarretta S, Dwinell MR, Hubner N, Volpe M.

J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701.

39.

The phenotypic impact of the male-specific region of chromosome-Y in inbred mating: the role of genetic variants and gene duplications in multiple inbred rat strains.

Prokop JW, Tsaih SW, Faber AB, Boehme S, Underwood AC, Troyer S, Playl L, Milsted A, Turner ME, Ely D, Martins AS, Tutaj M, Lazar J, Dwinell MR, Jacob HJ.

Biol Sex Differ. 2016 Feb 3;7:10. doi: 10.1186/s13293-016-0064-z. eCollection 2016.

40.

Rat Breeding Parameters According to Floor Space Available in Cage.

Allen KP, Dwinell MR, Zappa AM, Michaels AM, Murray KM, Thulin JD.

J Am Assoc Lab Anim Sci. 2016 Jan;55(1):21-4.

41.

Generation and characterization of mice harboring a conditional CXCL12 allele.

Hillmer RE, Boisvert JP, Cucciare MJ, Dwinell MB, Joksimovic M.

Int J Dev Biol. 2015;59(4-6):205-9. doi: 10.1387/ijdb.140348mj.

42.

Characterization of Dahl salt-sensitive rats with genetic disruption of the A2B adenosine receptor gene: implications for A2B adenosine receptor signaling during hypertension.

Nayak S, Khan MA, Wan TC, Pei H, Linden J, Dwinell MR, Geurts AM, Imig JD, Auchampach JA.

Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18.

43.

Pancreatic Cancer Cell Migration and Metastasis Is Regulated by Chemokine-Biased Agonism and Bioenergetic Signaling.

Roy I, McAllister DM, Gorse E, Dixon K, Piper CT, Zimmerman NP, Getschman AE, Tsai S, Engle DD, Evans DB, Volkman BF, Kalyanaraman B, Dwinell MB.

Cancer Res. 2015 Sep 1;75(17):3529-42. doi: 10.1158/0008-5472.CAN-14-2645.

44.

Correction: Astrocytes Directly Influence Tumor Cell Invasion and Metastasis In Vivo.

Wang L, Cossette SM, Rarick KR, Gershan J, Dwinell MB, Harder DR, Ramchandran R.

PLoS One. 2015 Aug 31;10(8):e0137369. doi: 10.1371/journal.pone.0137369. eCollection 2015. No abstract available.

45.

p38γ MAPK Is a Therapeutic Target for Triple-Negative Breast Cancer by Stimulation of Cancer Stem-Like Cell Expansion.

Qi X, Yin N, Ma S, Lepp A, Tang J, Jing W, Johnson B, Dwinell MB, Chitambar CR, Chen G.

Stem Cells. 2015 Sep;33(9):2738-47. doi: 10.1002/stem.2068. Epub 2015 Jun 23.

46.

Antiproliferative effects of mitochondria-targeted cationic antioxidants and analogs: Role of mitochondrial bioenergetics and energy-sensing mechanism.

Cheng G, Zielonka J, McAllister D, Hardy M, Ouari O, Joseph J, Dwinell MB, Kalyanaraman B.

Cancer Lett. 2015 Aug 28;365(1):96-106. doi: 10.1016/j.canlet.2015.05.016. Epub 2015 May 21.

47.

2015 Guidelines for Establishing Genetically Modified Rat Models for Cardiovascular Research.

Flister MJ, Prokop JW, Lazar J, Shimoyama M, Dwinell M, Geurts A; International Committee on Standardized Genetic Nomenclature for Mice; Rat Genome and Nomenclature Committee.

J Cardiovasc Transl Res. 2015 Jun;8(4):269-77. doi: 10.1007/s12265-015-9626-4. Epub 2015 Apr 29. Review.

48.

PhenoMiner: a quantitative phenotype database for the laboratory rat, Rattus norvegicus. Application in hypertension and renal disease.

Wang SJ, Laulederkind SJ, Hayman GT, Petri V, Liu W, Smith JR, Nigam R, Dwinell MR, Shimoyama M.

Database (Oxford). 2015 Jan 28;2015. pii: bau128. doi: 10.1093/database/bau128. Print 2015.

49.

OntoMate: a text-mining tool aiding curation at the Rat Genome Database.

Liu W, Laulederkind SJ, Hayman GT, Wang SJ, Nigam R, Smith JR, De Pons J, Dwinell MR, Shimoyama M.

Database (Oxford). 2015 Jan 25;2015. pii: bau129. doi: 10.1093/database/bau129. Print 2015.

50.

Enhancement of resting-state fcMRI networks by prior sensory stimulation.

Li C, Li Z, Ward BD, Dwinell MR, Lombard JH, Hudetz AG, Pawela CP.

Brain Connect. 2014 Nov;4(9):760-8. doi: 10.1089/brain.2014.0326.

Supplemental Content

Loading ...
Support Center