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Items: 49

1.

Comparison of agricultural injuries reported in the media and census of fatal occupational injuries.

New-Aaron M, Semin J, Duysen EG, Madsen M, Musil K, Rautiainen RH.

J Agromedicine. 2019 Jul;24(3):279-287. doi: 10.1080/1059924X.2019.1593276. Epub 2019 Mar 30.

PMID:
30890032
2.

Study of acetylcholinesterase activity and apoptosis in SH-SY5Y cells and mice exposed to ethanol.

Sun W, Chen L, Zheng W, Wei X, Wu W, Duysen EG, Jiang W.

Toxicology. 2017 Jun 1;384:33-39. doi: 10.1016/j.tox.2017.04.007. Epub 2017 Apr 17.

PMID:
28427893
3.

Polyclonal antibody to soman-tyrosine.

Li B, Duysen EG, Froment MT, Masson P, Nachon F, Jiang W, Schopfer LM, Thiele GM, Klassen LW, Cashman J, Williams GR, Lockridge O.

Chem Res Toxicol. 2013 Apr 15;26(4):584-92. doi: 10.1021/tx400027n. Epub 2013 Mar 21.

4.

Mice treated with a nontoxic dose of chlorpyrifos oxon have diethoxyphosphotyrosine labeled proteins in blood up to 4 days post exposure, detected by mass spectrometry.

Jiang W, Duysen EG, Lockridge O.

Toxicology. 2012 May 16;295(1-3):15-22. doi: 10.1016/j.tox.2012.03.001. Epub 2012 Mar 8.

PMID:
22406659
5.
6.

Production of ES1 plasma carboxylesterase knockout mice for toxicity studies.

Duysen EG, Koentgen F, Williams GR, Timperley CM, Schopfer LM, Cerasoli DM, Lockridge O.

Chem Res Toxicol. 2011 Nov 21;24(11):1891-8. doi: 10.1021/tx200237a. Epub 2011 Sep 7.

7.

Induction of plasma acetylcholinesterase activity in mice challenged with organophosphorus poisons.

Duysen EG, Lockridge O.

Toxicol Appl Pharmacol. 2011 Sep 1;255(2):214-20. doi: 10.1016/j.taap.2011.06.021. Epub 2011 Jul 2.

PMID:
21767560
8.

Prolonged toxic effects after cocaine challenge in butyrylcholinesterase/plasma carboxylesterase double knockout mice: a model for butyrylcholinesterase-deficient humans.

Duysen EG, Lockridge O.

Drug Metab Dispos. 2011 Aug;39(8):1321-3. doi: 10.1124/dmd.111.039917. Epub 2011 May 3.

PMID:
21540357
9.

Role of acetylcholinesterase on the structure and function of cholinergic synapses: insights gained from studies on knockout mice.

Adler M, Sweeney RE, Hamilton TA, Lockridge O, Duysen EG, Purcell AL, Deshpande SS.

Cell Mol Neurobiol. 2011 Aug;31(6):909-20. doi: 10.1007/s10571-011-9690-5. Epub 2011 May 3.

PMID:
21538119
10.

Gene-delivered butyrylcholinesterase is prophylactic against the toxicity of chemical warfare nerve agents and organophosphorus compounds.

Parikh K, Duysen EG, Snow B, Jensen NS, Manne V, Lockridge O, Chilukuri N.

J Pharmacol Exp Ther. 2011 Apr;337(1):92-101. doi: 10.1124/jpet.110.175646. Epub 2010 Dec 28.

PMID:
21205915
11.

Adenovirus-mediated human paraoxonase1 gene transfer to provide protection against the toxicity of the organophosphorus pesticide toxicant diazoxon.

Duysen EG, Parikh K, Aleti V, Manne V, Lockridge O, Chilukuri N.

Gene Ther. 2011 Mar;18(3):250-7. doi: 10.1038/gt.2010.136. Epub 2010 Oct 28.

PMID:
20981111
12.

Contributions of selective knockout studies to understanding cholinesterase disposition and function.

Camp S, Zhang L, Krejci E, Dobbertin A, Bernard V, Girard E, Duysen EG, Lockridge O, De Jaco A, Taylor P.

Chem Biol Interact. 2010 Sep 6;187(1-3):72-7. doi: 10.1016/j.cbi.2010.02.008. Epub 2010 Feb 11.

13.
14.

Drastic decrease in dopamine receptor levels in the striatum of acetylcholinesterase knock-out mouse.

Hrabovska A, Farar V, Bernard V, Duysen EG, Brabec J, Lockridge O, Myslivecek J.

Chem Biol Interact. 2010 Jan 5;183(1):194-201. doi: 10.1016/j.cbi.2009.09.025.

PMID:
19818744
15.

Mass spectrometry identifies multiple organophosphorylated sites on tubulin.

Grigoryan H, Schopfer LM, Peeples ES, Duysen EG, Grigoryan M, Thompson CM, Lockridge O.

Toxicol Appl Pharmacol. 2009 Oct 15;240(2):149-58. doi: 10.1016/j.taap.2009.07.020. Epub 2009 Jul 24.

16.

Adenovirus-transduced human butyrylcholinesterase in mouse blood functions as a bioscavenger of chemical warfare nerve agents.

Chilukuri N, Duysen EG, Parikh K, diTargiani R, Doctor BP, Lockridge O, Saxena A.

Mol Pharmacol. 2009 Sep;76(3):612-7. doi: 10.1124/mol.109.055665. Epub 2009 Jun 19.

PMID:
19542320
17.

Effects of rivastigmine and donepezil on brain acetylcholine levels in acetylcholinesterase-deficient mice.

Naik RS, Hartmann J, Kiewert C, Duysen EG, Lockridge O, Klein J.

J Pharm Pharm Sci. 2009;12(1):79-85.

18.
19.

The butyrylcholinesterase knockout mouse a research tool in the study of drug sensitivity, bio-distribution, obesity and Alzheimer's disease.

Duysen EG, Li B, Lockridge O.

Expert Opin Drug Metab Toxicol. 2009 May;5(5):523-8. doi: 10.1517/17425250902915555 . Review.

PMID:
19416087
20.

Increased hepatotoxicity and cardiac fibrosis in cocaine-treated butyrylcholinesterase knockout mice.

Duysen EG, Li B, Carlson M, Li YF, Wieseler S, Hinrichs SH, Lockridge O.

Basic Clin Pharmacol Toxicol. 2008 Dec;103(6):514-21. doi: 10.1111/j.1742-7843.2008.00259.x.

21.

Adenovirus-mediated gene transfer of human butyrylcholinesterase results in persistent high-level transgene expression in vivo.

Chilukuri N, Duysen EG, Parikh K, Sun W, Doctor BP, Lockridge O, Saxena A.

Chem Biol Interact. 2008 Sep 25;175(1-3):327-31. doi: 10.1016/j.cbi.2008.04.009. Epub 2008 May 21.

PMID:
18499092
22.

Whole body and tissue imaging of the butyrylcholinesterase knockout mouse injected with near infrared dye labeled butyrylcholinesterase.

Duysen EG, Lockridge O.

Chem Biol Interact. 2008 Sep 25;175(1-3):119-24. doi: 10.1016/j.cbi.2008.02.011. Epub 2008 Mar 7.

PMID:
18486120
23.

The butyrylcholinesterase knockout mouse is obese on a high-fat diet.

Li B, Duysen EG, Lockridge O.

Chem Biol Interact. 2008 Sep 25;175(1-3):88-91. doi: 10.1016/j.cbi.2008.03.009. Epub 2008 Mar 22.

PMID:
18452903
24.

The butyrylcholinesterase knockout mouse as a model for human butyrylcholinesterase deficiency.

Li B, Duysen EG, Carlson M, Lockridge O.

J Pharmacol Exp Ther. 2008 Mar;324(3):1146-54. Epub 2007 Dec 4.

PMID:
18056867
25.

Choline availability and acetylcholine synthesis in the hippocampus of acetylcholinesterase-deficient mice.

Hartmann J, Kiewert C, Duysen EG, Lockridge O, Klein J.

Neurochem Int. 2008 May;52(6):972-8. Epub 2007 Oct 16.

PMID:
18023504
26.

Adaptation to excess acetylcholine by downregulation of adrenoceptors and muscarinic receptors in lungs of acetylcholinesterase knockout mice.

Myslivecek J, Duysen EG, Lockridge O.

Naunyn Schmiedebergs Arch Pharmacol. 2007 Oct;376(1-2):83-92. Epub 2007 Sep 6.

PMID:
17805515
27.

Neuropathological and immunochemical studies of brain parenchyma in acetylcholinesterase knockout mice: implications in Alzheimer's disease.

Rice SG, Nowak L, Duysen EG, Lockridge O, Lahiri DK, Reyes PF.

J Alzheimers Dis. 2007 Jul;11(4):481-9.

PMID:
17656828
28.

Excessive hippocampal acetylcholine levels in acetylcholinesterase-deficient mice are moderated by butyrylcholinesterase activity.

Hartmann J, Kiewert C, Duysen EG, Lockridge O, Greig NH, Klein J.

J Neurochem. 2007 Mar;100(5):1421-9. Epub 2006 Dec 22.

30.

Production of the butyrylcholinesterase knockout mouse.

Li B, Duysen EG, Saunders TL, Lockridge O.

J Mol Neurosci. 2006;30(1-2):193-5.

PMID:
17192674
31.

Phenotype comparison of three acetylcholinesterase knockout strains.

Duysen EG, Lockridge O.

J Mol Neurosci. 2006;30(1-2):91-2.

PMID:
17192642
32.

Gene transfer of acetylcholinesterase protects the knockout mouse from the toxicity of DFP.

Li B, Duysen EG, Lockridge O.

J Mol Neurosci. 2006;30(1-2):79-80.

PMID:
17192637
33.

Protection from the toxicity of diisopropylfluorophosphate by adeno-associated virus expressing acetylcholinesterase.

Li B, Duysen EG, Poluektova LY, Murrin LC, Lockridge O.

Toxicol Appl Pharmacol. 2006 Jul 15;214(2):152-65. Epub 2006 Jan 26.

PMID:
16443250
34.

Delivery of human acetylcholinesterase by adeno-associated virus to the acetylcholinesterase knockout mouse.

Hrabovska A, Duysen EG, Sanders JD, Murrin LC, Lockridge O.

Chem Biol Interact. 2005 Dec 15;157-158:71-8. Epub 2005 Oct 21.

PMID:
16243306
35.

Butyrylcholinesterase, paraoxonase, and albumin esterase, but not carboxylesterase, are present in human plasma.

Li B, Sedlacek M, Manoharan I, Boopathy R, Duysen EG, Masson P, Lockridge O.

Biochem Pharmacol. 2005 Nov 25;70(11):1673-84. Epub 2005 Oct 6.

PMID:
16213467
36.

Life without acetylcholinesterase: the implications of cholinesterase inhibitor toxicity in AChE-knockout mice.

Lockridge O, Duysen EG, Voelker T, Thompson CM, Schopfer LM.

Environ Toxicol Pharmacol. 2005 May;19(3):463-9. doi: 10.1016/j.etap.2004.12.008. Epub 2005 Jan 26.

PMID:
21783513
37.

Albumin, a new biomarker of organophosphorus toxicant exposure, identified by mass spectrometry.

Peeples ES, Schopfer LM, Duysen EG, Spaulding R, Voelker T, Thompson CM, Lockridge O.

Toxicol Sci. 2005 Feb;83(2):303-12. Epub 2004 Nov 3.

PMID:
15525694
38.

Reduced acetylcholine receptor density, morphological remodeling, and butyrylcholinesterase activity can sustain muscle function in acetylcholinesterase knockout mice.

Adler M, Manley HA, Purcell AL, Deshpande SS, Hamilton TA, Kan RK, Oyler G, Lockridge O, Duysen EG, Sheridan RE.

Muscle Nerve. 2004 Sep;30(3):317-27.

PMID:
15318343
39.

Screening assays for cholinesterases resistant to inhibition by organophosphorus toxicants.

Wang Y, Schopfer LM, Duysen EG, Nachon F, Masson P, Lockridge O.

Anal Biochem. 2004 Jun 1;329(1):131-8.

PMID:
15136175
40.

Resistance to organophosphorus agent toxicity in transgenic mice expressing the G117H mutant of human butyrylcholinesterase.

Wang Y, Boeck AT, Duysen EG, Van Keuren M, Saunders TL, Lockridge O.

Toxicol Appl Pharmacol. 2004 May 1;196(3):356-66.

PMID:
15094306
41.

Altered striatal function and muscarinic cholinergic receptors in acetylcholinesterase knockout mice.

Volpicelli-Daley LA, Hrabovska A, Duysen EG, Ferguson SM, Blakely RD, Lockridge O, Levey AI.

Mol Pharmacol. 2003 Dec;64(6):1309-16.

PMID:
14645660
42.

Altered hippocampal muscarinic receptors in acetylcholinesterase-deficient mice.

Volpicelli-Daley LA, Duysen EG, Lockridge O, Levey AI.

Ann Neurol. 2003 Jun;53(6):788-96.

PMID:
12783426
43.

Regulation of muscarinic acetylcholine receptor function in acetylcholinesterase knockout mice.

Li B, Duysen EG, Volpicelli-Daley LA, Levey AI, Lockridge O.

Pharmacol Biochem Behav. 2003 Mar;74(4):977-86.

PMID:
12667913
44.
46.

Rescue of the acetylcholinesterase knockout mouse by feeding a liquid diet; phenotype of the adult acetylcholinesterase deficient mouse.

Duysen EG, Stribley JA, Fry DL, Hinrichs SH, Lockridge O.

Brain Res Dev Brain Res. 2002 Jul 30;137(1):43-54.

PMID:
12128253
47.

Acetylcholinesterase knockouts establish central cholinergic pathways and can use butyrylcholinesterase to hydrolyze acetylcholine.

Mesulam MM, Guillozet A, Shaw P, Levey A, Duysen EG, Lockridge O.

Neuroscience. 2002;110(4):627-39.

PMID:
11934471
48.

Evidence for nonacetylcholinesterase targets of organophosphorus nerve agent: supersensitivity of acetylcholinesterase knockout mouse to VX lethality.

Duysen EG, Li B, Xie W, Schopfer LM, Anderson RS, Broomfield CA, Lockridge O.

J Pharmacol Exp Ther. 2001 Nov;299(2):528-35.

PMID:
11602663
49.

Delivery of proteins from a controlled release injectable implant.

Yewey GL, Duysen EG, Cox SM, Dunn RL.

Pharm Biotechnol. 1997;10:93-117. Review. No abstract available.

PMID:
9160369

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