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Items: 1 to 50 of 107

1.

Folate deficiency promotes differentiation of vascular smooth muscle cells without affecting the methylation status of regulated genes.

Kolb AF, Petrie L, Mayer CD, Pirie L, Duthie SJ.

Biochem J. 2019 Sep 17. pii: BCJ20190275. doi: 10.1042/BCJ20190275. [Epub ahead of print]

PMID:
31530711
2.

Folate, genomic stability and colon cancer: The use of single cell gel electrophoresis in assessing the impact of folate in vitro, in vivo and in human biomonitoring.

Catala GN, Bestwick CS, Russell WR, Tortora K, Giovannelli L, Moyer MP, Lendoiro E, Duthie SJ.

Mutat Res. 2019 Jul;843:73-80. doi: 10.1016/j.mrgentox.2018.08.012. Epub 2018 Sep 5. Review.

PMID:
31421742
3.

Caspase-independence and characterization of bisnaphthalimidopropyl spermidine induced cytotoxicity in HL60 cells.

Bestwick CS, Milne L, Dance AM, Cochennec G, Cruickshank G, Allain E, Constable L, Duthie SJ, Thoo Lin PK.

Toxicol In Vitro. 2018 Oct;52:342-350. doi: 10.1016/j.tiv.2018.06.023. Epub 2018 Jul 23.

PMID:
29966682
4.

Roadmap for investigating epigenome deregulation and environmental origins of cancer.

Herceg Z, Ghantous A, Wild CP, Sklias A, Casati L, Duthie SJ, Fry R, Issa JP, Kellermayer R, Koturbash I, Kondo Y, Lepeule J, Lima SCS, Marsit CJ, Rakyan V, Saffery R, Taylor JA, Teschendorff AE, Ushijima T, Vineis P, Walker CL, Waterland RA, Wiemels J, Ambatipudi S, Degli Esposti D, Hernandez-Vargas H.

Int J Cancer. 2018 Mar 1;142(5):874-882. doi: 10.1002/ijc.31014. Epub 2017 Sep 13. Review.

5.

Effect of increasing fruit and vegetable intake by dietary intervention on nutritional biomarkers and attitudes to dietary change: a randomised trial.

Duthie SJ, Duthie GG, Russell WR, Kyle JAM, Macdiarmid JI, Rungapamestry V, Stephen S, Megias-Baeza C, Kaniewska JJ, Shaw L, Milne L, Bremner D, Ross K, Morrice P, Pirie LP, Horgan G, Bestwick CS.

Eur J Nutr. 2018 Aug;57(5):1855-1872. doi: 10.1007/s00394-017-1469-0. Epub 2017 May 30.

6.

Nutritional B vitamin deficiency alters the expression of key proteins associated with vascular smooth muscle cell proliferation and migration in the aorta of atherosclerotic apolipoprotein E null mice.

Duthie SJ, Beattie JH, Gordon MJ, Pirie LP, Nicol F, Reid MD, Duncan GJ, Cantlay L, Horgan G, McNeil CJ.

Genes Nutr. 2015 Jan;10(1):446. doi: 10.1007/s12263-014-0446-y. Epub 2014 Dec 2.

7.

Transcriptome analysis of peripheral blood mononuclear cells in human subjects following a 36 h fast provides evidence of effects on genes regulating inflammation, apoptosis and energy metabolism.

Elliott RM, de Roos B, Duthie SJ, Bouwman FG, Rubio-Aliaga I, Crosley LK, Mayer C, Polley AC, Heim C, Coort SL, Evelo CT, Mulholland F, Daniel H, Mariman EC, Johnson IT.

Genes Nutr. 2014 Nov;9(6):432. doi: 10.1007/s12263-014-0432-4. Epub 2014 Sep 27.

8.

Postprandial cell defense system responses to meal formulations: stratification through gene expression profiling.

Drew JE, Farquharson AJ, Horgan GW, Duthie SJ, Duthie GG.

Mol Nutr Food Res. 2014 Oct;58(10):2066-79. doi: 10.1002/mnfr.201400331. Epub 2014 Aug 4.

PMID:
25044795
9.

Homocysteine, antioxidant micronutrients and late onset dementia.

Whalley LJ, Duthie SJ, Collins AR, Starr JM, Deary IJ, Lemmon H, Duthie AC, Murray AD, Staff RT.

Eur J Nutr. 2014 Feb;53(1):277-85. doi: 10.1007/s00394-013-0526-6. Epub 2013 Apr 27.

PMID:
23625136
10.

Suboptimal dietary zinc intake promotes vascular inflammation and atherogenesis in a mouse model of atherosclerosis.

Beattie JH, Gordon MJ, Duthie SJ, McNeil CJ, Horgan GW, Nixon GF, Feldmann J, Kwun IS.

Mol Nutr Food Res. 2012 Jul;56(7):1097-105. doi: 10.1002/mnfr.201100776.

PMID:
22760982
11.

Differential effects of nutritional folic acid deficiency and moderate hyperhomocysteinemia on aortic plaque formation and genome-wide DNA methylation in vascular tissue from ApoE-/- mice.

McNeil CJ, Beattie JH, Gordon MJ, Pirie LP, Duthie SJ.

Clin Epigenetics. 2011 Aug;2(2):361-8. doi: 10.1007/s13148-011-0022-x. Epub 2011 Feb 20.

12.

Nutritional B vitamin deficiency disrupts lipid metabolism causing accumulation of proatherogenic lipoproteins in the aorta adventitia of ApoE null mice.

McNeil CJ, Beattie JH, Gordon MJ, Pirie LP, Duthie SJ.

Mol Nutr Food Res. 2012 Jul;56(7):1122-30. doi: 10.1002/mnfr.201100694. Epub 2012 May 18.

PMID:
22610982
13.

The influence of bisnaphthalimidopropyl polyamines on DNA instability and repair in Caco-2 colon epithelial cells.

Bestwick CS, Ralton LD, Milne L, Kong Thoo Lin P, Duthie SJ.

Cell Biol Toxicol. 2011 Dec;27(6):455-63. doi: 10.1007/s10565-011-9199-1. Epub 2011 Aug 13.

PMID:
21842340
14.

How the 1932 and 1947 mental surveys of Aberdeen schoolchildren provide a framework to explore the childhood origins of late onset disease and disability.

Whalley LJ, Murray AD, Staff RT, Starr JM, Deary IJ, Fox HC, Lemmon H, Duthie SJ, Collins AR, Crawford JR.

Maturitas. 2011 Aug;69(4):365-72. doi: 10.1016/j.maturitas.2011.05.010. Epub 2011 Jun 23.

PMID:
21700406
15.

2D-electrophoresis and multiplex immunoassay proteomic analysis of different body fluids and cellular components reveal known and novel markers for extended fasting.

Bouwman FG, de Roos B, Rubio-Aliaga I, Crosley LK, Duthie SJ, Mayer C, Horgan G, Polley AC, Heim C, Coort SL, Evelo CT, Mulholland F, Johnson IT, Elliott RM, Daniel H, Mariman EC.

BMC Med Genomics. 2011 Mar 25;4:24. doi: 10.1186/1755-8794-4-24.

16.

Epigenetic modifications and human pathologies: cancer and CVD.

Duthie SJ.

Proc Nutr Soc. 2011 Feb;70(1):47-56. doi: 10.1017/S0029665110003952. Epub 2010 Nov 11. Review.

PMID:
21067630
17.

Folate and cancer: how DNA damage, repair and methylation impact on colon carcinogenesis.

Duthie SJ.

J Inherit Metab Dis. 2011 Feb;34(1):101-9. doi: 10.1007/s10545-010-9128-0. Epub 2010 Jun 11. Review.

PMID:
20544289
18.

Blood folate status and expression of proteins involved in immune function, inflammation, and coagulation: biochemical and proteomic changes in the plasma of humans in response to long-term synthetic folic acid supplementation.

Duthie SJ, Horgan G, de Roos B, Rucklidge G, Reid M, Duncan G, Pirie L, Basten GP, Powers HJ.

J Proteome Res. 2010 Apr 5;9(4):1941-50. doi: 10.1021/pr901103n.

PMID:
20143872
19.

Folate deficiency alters hepatic and colon MGMT and OGG-1 DNA repair protein expression in rats but has no effect on genome-wide DNA methylation.

Duthie SJ, Grant G, Pirie LP, Watson AJ, Margison GP.

Cancer Prev Res (Phila). 2010 Jan;3(1):92-100. doi: 10.1158/1940-6207.CAPR-09-0231.

20.

Changes in vitamin biomarkers during a 2-year intervention trial involving increased fruit and vegetable consumption by free-living volunteers.

Macdonald HM, Hardcastle AC, Duthie GG, Duthie SJ, Aucott L, Sandison R, Shearer MJ, Reid DM.

Br J Nutr. 2009 Nov;102(10):1477-86. doi: 10.1017/S0007114509990377. Epub 2009 Jun 19.

PMID:
19538812
21.

Variation in protein levels obtained from human blood cells and biofluids for platelet, peripheral blood mononuclear cell, plasma, urine and saliva proteomics.

Crosley LK, Duthie SJ, Polley AC, Bouwman FG, Heim C, Mulholland F, Horgan G, Johnson IT, Mariman EC, Elliott RM, Daniel H, de Roos B.

Genes Nutr. 2009 Jun;4(2):95-102. doi: 10.1007/s12263-009-0121-x. Epub 2009 Apr 29.

22.

Rapid quantification of aortic lesions in apoE(-/-) mice.

Beattie JH, Duthie SJ, Kwun IS, Ha TY, Gordon MJ.

J Vasc Res. 2009;46(4):347-52. doi: 10.1159/000189795. Epub 2009 Jan 10.

23.

Folate and clefts of the lip and palate--a U.K.-based case-control study: Part II: Biochemical and genetic analysis.

Little J, Gilmour M, Mossey PA, Fitzpatrick D, Cardy A, Clayton-Smith J, Hill A, Duthie SJ, Fryer AE, Molloy AM, Scott JM; ITS MAGIC Collaboration.

Cleft Palate Craniofac J. 2008 Jul;45(4):428-38. doi: 10.1597/06-151.1. Epub 2007 Dec 23.

PMID:
18616362
24.

The response of human colonocytes to folate deficiency in vitro: functional and proteomic analyses.

Duthie SJ, Mavrommatis Y, Rucklidge G, Reid M, Duncan G, Moyer MP, Pirie LP, Bestwick CS.

J Proteome Res. 2008 Aug;7(8):3254-66. doi: 10.1021/pr700751y. Epub 2008 Jul 3.

PMID:
18597513
25.

Proteomic methodological recommendations for studies involving human plasma, platelets, and peripheral blood mononuclear cells.

de Roos B, Duthie SJ, Polley AC, Mulholland F, Bouwman FG, Heim C, Rucklidge GJ, Johnson IT, Mariman EC, Daniel H, Elliott RM.

J Proteome Res. 2008 Jun;7(6):2280-90. doi: 10.1021/pr700714x. Epub 2008 May 20.

PMID:
18489134
26.

Kaempferol induced inhibition of HL-60 cell growth results from a heterogeneous response, dominated by cell cycle alterations.

Bestwick CS, Milne L, Duthie SJ.

Chem Biol Interact. 2007 Nov 20;170(2):76-85. Epub 2007 Jul 18.

PMID:
17765212
27.
28.

Biphasic effect of falcarinol on caco-2 cell proliferation, DNA damage, and apoptosis.

Young JF, Duthie SJ, Milne L, Christensen LP, Duthie GG, Bestwick CS.

J Agric Food Chem. 2007 Feb 7;55(3):618-23.

PMID:
17263451
29.

Sensitivity of markers of DNA stability and DNA repair activity to folate supplementation in healthy volunteers.

Basten GP, Duthie SJ, Pirie L, Vaughan N, Hill MH, Powers HJ.

Br J Cancer. 2006 Jun 19;94(12):1942-7. Epub 2006 May 30.

30.

Halving of body weight: a case of an ovarian mucinous cystadenoma.

Aslam MF, Bedford NA, Sissons MC, Sooltan AR, Duthie SJ.

Eur J Gynaecol Oncol. 2006;27(1):88-9.

PMID:
16550979
31.

The effects of cranberry juice consumption on antioxidant status and biomarkers relating to heart disease and cancer in healthy human volunteers.

Duthie SJ, Jenkinson AM, Crozier A, Mullen W, Pirie L, Kyle J, Yap LS, Christen P, Duthie GG.

Eur J Nutr. 2006 Mar;45(2):113-22. Epub 2005 Jul 20.

PMID:
16032375
32.

The effect of short-term kaempferol exposure on reactive oxygen levels and integrity of human (HL-60) leukaemic cells.

Bestwick CS, Milne L, Pirie L, Duthie SJ.

Biochim Biophys Acta. 2005 Jun 10;1740(3):340-9. Epub 2004 Nov 3.

33.

Folate, DNA stability and colo-rectal neoplasia.

Duthie SJ, Narayanan S, Sharp L, Little J, Basten G, Powers H.

Proc Nutr Soc. 2004 Nov;63(4):571-8. Review.

PMID:
15831129
34.

Increased salicylate concentrations in urine of human volunteers after consumption of cranberry juice.

Duthie GG, Kyle JA, Jenkinson AM, Duthie SJ, Baxter GJ, Paterson JR.

J Agric Food Chem. 2005 Apr 20;53(8):2897-900.

PMID:
15826036
35.

The influence of moderate red wine consumption on antioxidant status and indices of oxidative stress associated with CHD in healthy volunteers.

Tsang C, Higgins S, Duthie GG, Duthie SJ, Howie M, Mullen W, Lean ME, Crozier A.

Br J Nutr. 2005 Feb;93(2):233-40.

PMID:
15788107
36.
38.

DNA stability and lipid peroxidation in vitamin E-deficient rats in vivo and colon cells in vitro--modulation by the dietary anthocyanin, cyanidin-3-glycoside.

Duthie SJ, Gardner PT, Morrice PC, Wood SG, Pirie L, Bestwick CC, Milne L, Duthie GG.

Eur J Nutr. 2005 Jun;44(4):195-203. Epub 2004 Jul 9.

PMID:
15309415
39.

Effect of folic Acid supplementation on the folate status of buccal mucosa and lymphocytes.

Basten GP, Hill MH, Duthie SJ, Powers HJ.

Cancer Epidemiol Biomarkers Prev. 2004 Jul;13(7):1244-9.

40.

Dietary supplement use in old age: associations with childhood IQ, current cognition and health.

Whalley LJ, Fox HC, Lemmon HA, Duthie SJ, Collins AR, Peace H, Starr JM, Deary IJ.

Int J Geriatr Psychiatry. 2003 Sep;18(9):769-76.

PMID:
12949843
41.

Plasma vitamin C, cholesterol and homocysteine are associated with grey matter volume determined by MRI in non-demented old people.

Whalley LJ, Staff RT, Murray AD, Duthie SJ, Collins AR, Lemmon HA, Starr JM, Deary IJ.

Neurosci Lett. 2003 May 8;341(3):173-6.

PMID:
12697276
42.

Can cardiotocography prior to induction of labour predict obstetric intervention? A pilot study.

Hardwick JC, Duthie SJ.

J Obstet Gynaecol. 2001 May;21(3):258-60.

PMID:
12521855
43.

Serum concentrations of homocysteine are elevated during early pregnancy in rodent models of fetal programming.

Petrie L, Duthie SJ, Rees WD, McConnell JM.

Br J Nutr. 2002 Nov;88(5):471-7.

PMID:
12425727
44.

Impact of folate deficiency on DNA stability.

Duthie SJ, Narayanan S, Brand GM, Pirie L, Grant G.

J Nutr. 2002 Aug;132(8 Suppl):2444S-2449S. doi: 10.1093/jn/132.8.2444S.

PMID:
12163709
45.

Homocysteine, B vitamin status, and cognitive function in the elderly.

Duthie SJ, Whalley LJ, Collins AR, Leaper S, Berger K, Deary IJ.

Am J Clin Nutr. 2002 May;75(5):908-13. Erratum in: Am J Clin Nutr. 2003 Feb;77(2):523..

PMID:
11976166
46.
47.

[Effects of vitamins E, C and beta-carotene on DNA damage].

Ma A, Duthie SJ, Ross MA, Collins AR.

Zhonghua Yu Fang Yi Xue Za Zhi. 1999 Jan;33(1):16-7. Chinese.

PMID:
11864448
48.

Lysis of whole blood in vitro causes DNA strand breaks in human lymphocytes.

Narayanan S, O'Donovan MR, Duthie SJ.

Mutagenesis. 2001 Nov;16(6):455-9.

PMID:
11682634
49.

Anthocyanin-rich extract decreases indices of lipid peroxidation and DNA damage in vitamin E-depleted rats.

Ramirez-Tortosa C, Andersen ØM, Cabrita L, Gardner PT, Morrice PC, Wood SG, Duthie SJ, Collins AR, Duthie GG.

Free Radic Biol Med. 2001 Nov 1;31(9):1033-7. Erratum in: Free Radic Biol Med. 2012 Jul 15;53(2):249. Cabrita, Luis [added].

PMID:
11677035
50.

Folic-acid-mediated inhibition of human colon-cancer cell growth.

Duthie SJ.

Nutrition. 2001 Sep;17(9):736-7. No abstract available.

PMID:
11527664

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