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Items: 24

1.

N-demethylation of N-methyl-4-aminoantipyrine, the main metabolite of metamizole.

Bachmann F, Duthaler U, Rudin D, Krähenbühl S, Haschke M.

Eur J Pharm Sci. 2018 Jul 30;120:172-180. doi: 10.1016/j.ejps.2018.05.003. Epub 2018 May 8.

PMID:
29746911
2.

Effect of Toxicants on Fatty Acid Metabolism in HepG2 Cells.

Grünig D, Duthaler U, Krähenbühl S.

Front Pharmacol. 2018 Apr 23;9:257. doi: 10.3389/fphar.2018.00257. eCollection 2018.

3.

Effect of the catechol-O-methyltransferase inhibitors tolcapone and entacapone on fatty acid metabolism in HepaRG cells.

Grünig D, Felser A, Duthaler U, Bouitbir J, Krähenbühl S.

Toxicol Sci. 2018 Apr 23. doi: 10.1093/toxsci/kfy101. [Epub ahead of print]

PMID:
29688484
4.

Automated high throughput analysis of antiretroviral drugs in dried blood spots.

Duthaler U, Berger B, Erb S, Battegay M, Letang E, Gaugler S, Krähenbühl S, Haschke M.

J Mass Spectrom. 2017 Aug;52(8):534-542. doi: 10.1002/jms.3952.

PMID:
28557187
5.

Health care provider communication training in rural Tanzania empowers HIV-infected patients on antiretroviral therapy to discuss adherence problems.

Erb S, Letang E, Glass TR, Natamatungiro A, Mnzava D, Mapesi H, Haschke M, Duthaler U, Berger B, Muri L, Bader J, Marzolini C, Elzi L, Klimkait T, Langewitz W, Battegay M; Kilombero Ulanga Antiretroviral Cohort (KIULARCO) study group.

HIV Med. 2017 Oct;18(9):623-634. doi: 10.1111/hiv.12499. Epub 2017 Mar 13.

6.

Impaired Exercise Performance and Skeletal Muscle Mitochondrial Function in Rats with Secondary Carnitine Deficiency.

Bouitbir J, Haegler P, Singh F, Joerin L, Felser A, Duthaler U, Krähenbühl S.

Front Physiol. 2016 Aug 10;7:345. doi: 10.3389/fphys.2016.00345. eCollection 2016.

7.

Efficacy and safety of tribendimidine against Opisthorchis viverrini: two randomised, parallel-group, single-blind, dose-ranging, phase 2 trials.

Sayasone S, Odermatt P, Vonghachack Y, Xayavong S, Senggnam K, Duthaler U, Akkhavong K, Hattendorf J, Keiser J.

Lancet Infect Dis. 2016 Oct;16(10):1145-1153. doi: 10.1016/S1473-3099(16)30198-0. Epub 2016 Jul 26.

PMID:
27472949
8.

Single-Ascending-Dose Pharmacokinetic Study of Tribendimidine in Opisthorchis viverrini-Infected Patients.

Duthaler U, Sayasone S, Vanobbergen F, Penny MA, Odermatt P, Huwyler J, Keiser J.

Antimicrob Agents Chemother. 2016 Sep 23;60(10):5705-15. doi: 10.1128/AAC.00992-16. Print 2016 Oct.

9.

Population Pharmacokinetic Modeling of Tribendimidine Metabolites in Opisthorchis viverrini-Infected Adults.

Vanobberghen F, Penny MA, Duthaler U, Odermatt P, Sayasone S, Keiser J, Tarning J.

Antimicrob Agents Chemother. 2016 Sep 23;60(10):5695-704. doi: 10.1128/AAC.00655-16. Print 2016 Oct.

10.

Pharmacokinetic Study of Praziquantel Enantiomers and Its Main Metabolite R-trans-4-OH-PZQ in Plasma, Blood and Dried Blood Spots in Opisthorchis viverrini-Infected Patients.

Meister I, Kovac J, Duthaler U, Odermatt P, Huwyler J, Vanobberghen F, Sayasone S, Keiser J.

PLoS Negl Trop Dis. 2016 May 6;10(5):e0004700. doi: 10.1371/journal.pntd.0004700. eCollection 2016 May.

11.

Development and validation of an enantioselective LC-MS/MS method for the analysis of the anthelmintic drug praziquantel and its main metabolite in human plasma, blood and dried blood spots.

Meister I, Leonidova A, Kovač J, Duthaler U, Keiser J, Huwyler J.

J Pharm Biomed Anal. 2016 Jan 25;118:81-88. doi: 10.1016/j.jpba.2015.10.011. Epub 2015 Oct 22.

PMID:
26517852
12.

Interactions between bupropion and 3,4-methylenedioxymethamphetamine in healthy subjects.

Schmid Y, Rickli A, Schaffner A, Duthaler U, Grouzmann E, Hysek CM, Liechti ME.

J Pharmacol Exp Ther. 2015 Apr;353(1):102-11. doi: 10.1124/jpet.114.222356. Epub 2015 Feb 5.

13.

LC-MS/MS method for the determination of two metabolites of tribendimidine, deacylated amidantel and its acetylated metabolite in plasma, blood and dried blood spots.

Duthaler U, Keiser J, Huwyler J.

J Pharm Biomed Anal. 2015 Feb;105:163-73. doi: 10.1016/j.jpba.2014.12.006. Epub 2014 Dec 12.

PMID:
25553533
14.

Repurposing drugs for the treatment and control of helminth infections.

Panic G, Duthaler U, Speich B, Keiser J.

Int J Parasitol Drugs Drug Resist. 2014 Jul 30;4(3):185-200. doi: 10.1016/j.ijpddr.2014.07.002. eCollection 2014 Dec. Review.

15.

Efficacy and pharmacokinetics of OZ78 and MT04 against a natural infection with Fasciola hepatica in sheep.

Meister I, Duthaler U, Huwyler J, Rinaldi L, Bosco A, Cringoli G, Keiser J.

Vet Parasitol. 2013 Nov 15;198(1-2):102-10. doi: 10.1016/j.vetpar.2013.08.007. Epub 2013 Aug 14.

PMID:
24011678
16.

Disposition of mefloquine and enpiroline is highly influenced by a chronic Schistosoma mansoni infection.

Ingram K, Duthaler U, Vargas M, Ellis W, Keiser J.

Antimicrob Agents Chemother. 2013 Sep;57(9):4506-11. doi: 10.1128/AAC.01129-13. Epub 2013 Jul 8.

17.

Systematic evaluation of extraction methods for multiplatform-based metabotyping: application to the Fasciola hepatica metabolome.

Saric J, Want EJ, Duthaler U, Lewis M, Keiser J, Shockcor JP, Ross GA, Nicholson JK, Holmes E, Tavares MF.

Anal Chem. 2012 Aug 21;84(16):6963-72. doi: 10.1021/ac300586m. Epub 2012 Aug 10.

18.

Trematode infections: liver and lung flukes.

Fürst T, Duthaler U, Sripa B, Utzinger J, Keiser J.

Infect Dis Clin North Am. 2012 Jun;26(2):399-419. doi: 10.1016/j.idc.2012.03.008.

PMID:
22632646
19.

Evaluation of the pharmacokinetic profile of artesunate, artemether and their metabolites in sheep naturally infected with Fasciola hepatica.

Duthaler U, Huwyler J, Rinaldi L, Cringoli G, Keiser J.

Vet Parasitol. 2012 May 25;186(3-4):270-80. doi: 10.1016/j.vetpar.2011.11.076. Epub 2011 Dec 6.

PMID:
22206644
21.

In vivo and in vitro sensitivity of Fasciola hepatica to triclabendazole combined with artesunate, artemether, or OZ78.

Duthaler U, Smith TA, Keiser J.

Antimicrob Agents Chemother. 2010 Nov;54(11):4596-604. doi: 10.1128/AAC.00828-10. Epub 2010 Aug 23.

22.

Update on the diagnosis and treatment of food-borne trematode infections.

Keiser J, Duthaler U, Utzinger J.

Curr Opin Infect Dis. 2010 Oct;23(5):513-20. doi: 10.1097/QCO.0b013e32833de06a. Review.

PMID:
20683264
23.

Fasciola hepatica: comparison of the sedimentation and FLOTAC techniques for the detection and quantification of faecal egg counts in rats.

Duthaler U, Rinaldi L, Maurelli MP, Vargas M, Utzinger J, Cringoli G, Keiser J.

Exp Parasitol. 2010 Oct;126(2):161-6. doi: 10.1016/j.exppara.2010.04.020. Epub 2010 Apr 29.

PMID:
20434442
24.

Anthelmintic activity of artesunate against Fasciola hepatica in naturally infected sheep.

Keiser J, Veneziano V, Rinaldi L, Mezzino L, Duthaler U, Cringoli G.

Res Vet Sci. 2010 Feb;88(1):107-10. doi: 10.1016/j.rvsc.2009.05.007. Epub 2009 Jun 5.

PMID:
19501379

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