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Items: 1 to 50 of 125

1.

Using real-world data to evaluate biosimilar switching.

Dutcher SK, Eworuke E, Blum MD, Ball R.

Pharmacoepidemiol Drug Saf. 2019 Nov 6. doi: 10.1002/pds.4899. [Epub ahead of print] No abstract available.

PMID:
31692176
2.

Author Correction: Exome sequencing of Finnish isolates enhances rare-variant association power.

Locke AE, Steinberg KM, Chiang CWK, Service SK, Havulinna AS, Stell L, Pirinen M, Abel HJ, Chiang CC, Fulton RS, Jackson AU, Kang CJ, Kanchi KL, Koboldt DC, Larson DE, Nelson J, Nicholas TJ, Pietilä A, Ramensky V, Ray D, Scott LJ, Stringham HM, Vangipurapu J, Welch R, Yajnik P, Yin X, Eriksson JG, Ala-Korpela M, Järvelin MR, Männikkö M, Laivuori H; FinnGen Project, Dutcher SK, Stitziel NO, Wilson RK, Hall IM, Sabatti C, Palotie A, Salomaa V, Laakso M, Ripatti S, Boehnke M, Freimer NB.

Nature. 2019 Nov;575(7783):E4. doi: 10.1038/s41586-019-1726-x.

PMID:
31686056
3.

Structure of the Decorated Ciliary Doublet Microtubule.

Ma M, Stoyanova M, Rademacher G, Dutcher SK, Brown A, Zhang R.

Cell. 2019 Oct 31;179(4):909-922.e12. doi: 10.1016/j.cell.2019.09.030. Epub 2019 Oct 24.

PMID:
31668805
4.

De Novo Mutations in FOXJ1 Result in a Motile Ciliopathy with Hydrocephalus and Randomization of Left/Right Body Asymmetry.

Wallmeier J, Frank D, Shoemark A, Nöthe-Menchen T, Cindric S, Olbrich H, Loges NT, Aprea I, Dougherty GW, Pennekamp P, Kaiser T, Mitchison HM, Hogg C, Carr SB, Zariwala MA, Ferkol T, Leigh MW, Davis SD, Atkinson J, Dutcher SK, Knowles MR, Thiele H, Altmüller J, Krenz H, Wöste M, Brentrup A, Ahrens F, Vogelberg C, Morris-Rosendahl DJ, Omran H.

Am J Hum Genet. 2019 Nov 7;105(5):1030-1039. doi: 10.1016/j.ajhg.2019.09.022. Epub 2019 Oct 17.

PMID:
31630787
5.

HY-DIN' in the Cilia: Discovery of Central Pair-Related Mutations in Primary Ciliary Dyskinesia.

Dutcher SK, Brody SL.

Am J Respir Cell Mol Biol. 2019 Oct 11. doi: 10.1165/rcmb.2019-0316ED. [Epub ahead of print] No abstract available.

PMID:
31604022
6.

Use of Sodium-Glucose Cotransporter 2 Inhibitors in Patients With Type 1 Diabetes and Rates of Diabetic Ketoacidosis.

Hampp C, Swain RS, Horgan C, Dee E, Qiang Y, Dutcher SK, Petrone A, Chen Tilney R, Maro JC, Panozzo CA.

Diabetes Care. 2019 Oct 10. pii: dc191481. doi: 10.2337/dc19-1481. [Epub ahead of print]

PMID:
31601640
7.

Cytoplasmic "ciliary inclusions" in isolation are not sufficient for the diagnosis of primary ciliary dyskinesia.

Vece TJ, Sagel SD, Zariwala MA, Sullivan KM, Burns KA, Dutcher SK, Yusupov R, Leigh MW, Knowles MR.

Pediatr Pulmonol. 2019 Sep 23. doi: 10.1002/ppul.24528. [Epub ahead of print]

PMID:
31549486
8.

Dynein tails: how to hitch a ride on an IFT train.

Dutcher SK.

Nat Struct Mol Biol. 2019 Sep;26(9):760-761. doi: 10.1038/s41594-019-0285-z. No abstract available.

PMID:
31451805
9.

Exome sequencing of Finnish isolates enhances rare-variant association power.

Locke AE, Steinberg KM, Chiang CWK, Service SK, Havulinna AS, Stell L, Pirinen M, Abel HJ, Chiang CC, Fulton RS, Jackson AU, Kang CJ, Kanchi KL, Koboldt DC, Larson DE, Nelson J, Nicholas TJ, Pietilä A, Ramensky V, Ray D, Scott LJ, Stringham HM, Vangipurapu J, Welch R, Yajnik P, Yin X, Eriksson JG, Ala-Korpela M, Järvelin MR, Männikkö M, Laivuori H; FinnGen Project, Dutcher SK, Stitziel NO, Wilson RK, Hall IM, Sabatti C, Palotie A, Salomaa V, Laakso M, Ripatti S, Boehnke M, Freimer NB.

Nature. 2019 Aug;572(7769):323-328. doi: 10.1038/s41586-019-1457-z. Epub 2019 Jul 31. Erratum in: Nature. 2019 Nov;575(7783):E4.

PMID:
31367044
10.

Acoustic trap-and-release for rapid assessment of cell motility.

Kim M, Huff E, Bottier M, Dutcher SK, Bayly PV, Meacham JM.

Soft Matter. 2019 May 29;15(21):4266-4275. doi: 10.1039/c9sm00184k.

PMID:
30968924
11.

How Does Cilium Length Affect Beating?

Bottier M, Thomas KA, Dutcher SK, Bayly PV.

Biophys J. 2019 Apr 2;116(7):1292-1304. doi: 10.1016/j.bpj.2019.02.012. Epub 2019 Feb 26.

PMID:
30878201
12.

Comparative effectiveness of generic and brand-name medication use: A database study of US health insurance claims.

Desai RJ, Sarpatwari A, Dejene S, Khan NF, Lii J, Rogers JR, Dutcher SK, Raofi S, Bohn J, Connolly JG, Fischer MA, Kesselheim AS, Gagne JJ.

PLoS Med. 2019 Mar 13;16(3):e1002763. doi: 10.1371/journal.pmed.1002763. eCollection 2019 Mar.

13.

Secular Trends in the Cost of Immunosuppressants after Solid Organ Transplantation in the United States.

Helmuth ME, Liu Q, Turenne MN, Park JM, Oguntimein M, Dutcher SK, Balkrishnan R, Sharma P, Zee J, Leichtman AB, Smith AR.

Clin J Am Soc Nephrol. 2019 Mar 7;14(3):421-430. doi: 10.2215/CJN.10590918. Epub 2019 Feb 28.

PMID:
30819667
14.

Generic and Brand-Name Thyroid Hormone Drug Use Among Commercially Insured and Medicare Beneficiaries, 2007 Through 2016.

Ross JS, Rohde S, Sangaralingham L, Brito JP, Choi L, Dutcher SK, Graham DJ, Jenkins MR, Lipska KJ, Mendoza M, Qiang Y, Wang Z, Wu Y, Yao X, Shah ND.

J Clin Endocrinol Metab. 2019 Jun 1;104(6):2305-2314. doi: 10.1210/jc.2018-02197.

PMID:
30690529
15.

Characterizing the Major Structural Variant Alleles of the Human Genome.

Audano PA, Sulovari A, Graves-Lindsay TA, Cantsilieris S, Sorensen M, Welch AE, Dougherty ML, Nelson BJ, Shah A, Dutcher SK, Warren WC, Magrini V, McGrath SD, Li YI, Wilson RK, Eichler EE.

Cell. 2019 Jan 24;176(3):663-675.e19. doi: 10.1016/j.cell.2018.12.019. Epub 2019 Jan 17.

16.

Evaluation of Socioeconomic Status Indicators for Confounding Adjustment in Observational Studies of Medication Use.

Gopalakrishnan C, Gagne JJ, Sarpatwari A, Dejene SZ, Dutcher SK, Levin R, Franklin JM, Schneeweiss S, Desai RJ.

Clin Pharmacol Ther. 2019 Jun;105(6):1513-1521. doi: 10.1002/cpt.1348. Epub 2019 Feb 25.

PMID:
30659590
17.

Determinants of Generic Drug Substitution in the United States.

Segal JB, Onasanya O, Daubresse M, Lee CY, Moechtar M, Pu X, Dutcher SK, Romanelli RJ.

Ther Innov Regul Sci. 2019 Jan 13:2168479018820050. doi: 10.1177/2168479018820050. [Epub ahead of print]

PMID:
30636440
18.

A Survey of Patients' Perceptions of Pill Appearance and Responses to Changes in Appearance for Four Chronic Disease Medications.

Sarpatwari A, Gagne JJ, Lu Z, Campbell EG, Carman WJ, Enger CL, Dutcher SK, Jiang W, Kesselheim AS.

J Gen Intern Med. 2019 Mar;34(3):420-428. doi: 10.1007/s11606-018-4791-1. Epub 2019 Jan 10.

PMID:
30632102
19.

RPGRIP1L helps to establish the ciliary gate for entry of proteins.

Lin H, Guo S, Dutcher SK.

J Cell Sci. 2018 Oct 26;131(20). pii: jcs220905. doi: 10.1242/jcs.220905.

20.

MAPINS, a Highly Efficient Detection Method That Identifies Insertional Mutations and Complex DNA Rearrangements.

Lin H, Cliften PF, Dutcher SK.

Plant Physiol. 2018 Dec;178(4):1436-1447. doi: 10.1104/pp.18.00474. Epub 2018 Sep 11.

21.

Evaluation of Switching Patterns in FDA's Sentinel System: A New Tool to Assess Generic Drugs.

Gagne JJ, Popovic JR, Nguyen M, Sandhu SK, Greene P, Izem R, Jiang W, Wang Z, Zhao Y, Petrone AB, Wagner AK, Dutcher SK.

Drug Saf. 2018 Dec;41(12):1313-1323. doi: 10.1007/s40264-018-0709-4.

PMID:
30120741
22.

Functional characterization of biallelic RTTN variants identified in an infant with microcephaly, simplified gyral pattern, pontocerebellar hypoplasia, and seizures.

Wambach JA, Wegner DJ, Yang P, Shinawi M, Baldridge D, Betleja E, Shimony JS, Spencer D, Hackett BP, Andrews MV, Ferkol T, Dutcher SK, Mahjoub MR, Cole FS.

Pediatr Res. 2018 Sep;84(3):435-441. doi: 10.1038/s41390-018-0083-z. Epub 2018 Jun 4.

23.

High-resolution comparative analysis of great ape genomes.

Kronenberg ZN, Fiddes IT, Gordon D, Murali S, Cantsilieris S, Meyerson OS, Underwood JG, Nelson BJ, Chaisson MJP, Dougherty ML, Munson KM, Hastie AR, Diekhans M, Hormozdiari F, Lorusso N, Hoekzema K, Qiu R, Clark K, Raja A, Welch AE, Sorensen M, Baker C, Fulton RS, Armstrong J, Graves-Lindsay TA, Denli AM, Hoppe ER, Hsieh P, Hill CM, Pang AWC, Lee J, Lam ET, Dutcher SK, Gage FH, Warren WC, Shendure J, Haussler D, Schneider VA, Cao H, Ventura M, Wilson RK, Paten B, Pollen A, Eichler EE.

Science. 2018 Jun 8;360(6393). pii: eaar6343. doi: 10.1126/science.aar6343.

24.

Differences in rates of switchbacks after switching from branded to authorized generic and branded to generic drug products: cohort study.

Desai RJ, Sarpatwari A, Dejene S, Khan NF, Lii J, Rogers JR, Dutcher SK, Raofi S, Bohn J, Connolly J, Fischer MA, Kesselheim AS, Gagne JJ.

BMJ. 2018 Apr 3;361:k1180. doi: 10.1136/bmj.k1180.

25.

Correction to: Outcomes Associated with Generic Drugs Approved Using Product-Specific Determinations of Therapeutic Equivalence.

Gagne JJ, Polinski JM, Jiang W, Dutcher SK, Xie J, Lii J, Fulchino LA, Kesselheim AS.

Drugs. 2018 Mar;78(4):523-524. doi: 10.1007/s40265-018-0890-x.

PMID:
29520639
26.

Identifying RNA splicing factors using IFT genes in Chlamydomonas reinhardtii.

Lin H, Zhang Z, Iomini C, Dutcher SK.

Open Biol. 2018 Mar;8(3). pii: 170211. doi: 10.1098/rsob.170211.

27.

The IDA3 adapter, required for intraflagellar transport of I1 dynein, is regulated by ciliary length.

Hunter EL, Lechtreck K, Fu G, Hwang J, Lin H, Gokhale A, Alford LM, Lewis B, Yamamoto R, Kamiya R, Yang F, Nicastro D, Dutcher SK, Wirschell M, Sale WS.

Mol Biol Cell. 2018 Apr 15;29(8):886-896. doi: 10.1091/mbc.E17-12-0729. Epub 2018 Mar 29.

28.

Generic Versions of Narrow Therapeutic Index Drugs: A National Survey of Pharmacists' Substitution Beliefs and Practices.

Sarpatwari A, Lee MP, Gagne JJ, Lu Z, Dutcher SK, Jiang W, Campbell EG, Kesselheim AS.

Clin Pharmacol Ther. 2018 Jun;103(6):1093-1099. doi: 10.1002/cpt.884. Epub 2017 Nov 22.

PMID:
29165800
29.

Chlamydomonas DYX1C1/PF23 is essential for axonemal assembly and proper morphology of inner dynein arms.

Yamamoto R, Obbineni JM, Alford LM, Ide T, Owa M, Hwang J, Kon T, Inaba K, James N, King SM, Ishikawa T, Sale WS, Dutcher SK.

PLoS Genet. 2017 Sep 11;13(9):e1006996. doi: 10.1371/journal.pgen.1006996. eCollection 2017 Sep. Erratum in: PLoS Genet. 2017 Oct 23;13(10 ):e1007063.

30.

Provider and Patient Determinants of Generic Levothyroxine Prescribing: An Electronic Health Records-Based Study.

Romanelli RJ, Nimbal V, Dutcher SK, Pu X, Segal JB.

Ann Pharmacother. 2017 Aug;51(8):640-648. doi: 10.1177/1060028017705393. Epub 2017 Apr 20.

PMID:
28425295
31.

Outcomes Associated with Generic Drugs Approved Using Product-Specific Determinations of Therapeutic Equivalence.

Gagne JJ, Polinski JM, Jiang W, Dutcher SK, Xie J, Lii J, Fulchino LA, Kesselheim AS.

Drugs. 2017 Mar;77(4):427-433. doi: 10.1007/s40265-017-0696-2. Erratum in: Drugs. 2018 Mar 8;:.

PMID:
28181177
32.

Comparison of Generic-to-Brand Switchback Rates Between Generic and Authorized Generic Drugs.

Hansen RA, Qian J, Berg R, Linneman J, Seoane-Vazquez E, Dutcher SK, Raofi S, Page CD, Peissig P.

Pharmacotherapy. 2017 Apr;37(4):429-437. doi: 10.1002/phar.1908. Epub 2017 Mar 20.

33.
34.

Flexural Rigidity and Shear Stiffness of Flagella Estimated from Induced Bends and Counterbends.

Xu G, Wilson KS, Okamoto RJ, Shao JY, Dutcher SK, Bayly PV.

Biophys J. 2016 Jun 21;110(12):2759-2768. doi: 10.1016/j.bpj.2016.05.017.

35.

The basal bodies of Chlamydomonas reinhardtii.

Dutcher SK, O'Toole ET.

Cilia. 2016 Jun 1;5:18. doi: 10.1186/s13630-016-0039-z. eCollection 2016. Review.

36.

Switch-backs associated with generic drugs approved using product-specific determinations of therapeutic equivalence.

Gagne JJ, Polinski JM, Jiang W, Dutcher SK, Xie J, Lii J, Fulchino LA, Kesselheim AS.

Pharmacoepidemiol Drug Saf. 2016 Aug;25(8):944-52. doi: 10.1002/pds.4009. Epub 2016 Apr 22.

PMID:
27102378
37.

Correction: Katanin Localization Requires Triplet Microtubules in Chlamydomonas reinhardtii.

Esparza JM, O'Toole E, Li L, Giddings TH Jr, Kozak B, Albee AJ, Dutcher SK.

PLoS One. 2016 Jan 15;11(1):e0145569. doi: 10.1371/journal.pone.0145569. eCollection 2016. No abstract available.

38.

Genetics and biology of primary ciliary dyskinesia.

Horani A, Ferkol TW, Dutcher SK, Brody SL.

Paediatr Respir Rev. 2016 Mar;18:18-24. doi: 10.1016/j.prrv.2015.09.001. Epub 2015 Sep 11. Review.

39.

A NIMA-Related Kinase Suppresses the Flagellar Instability Associated with the Loss of Multiple Axonemal Structures.

Lin H, Zhang Z, Guo S, Chen F, Kessler JM, Wang YM, Dutcher SK.

PLoS Genet. 2015 Sep 8;11(9):e1005508. doi: 10.1371/journal.pgen.1005508. eCollection 2015 Sep.

40.

Dynein-deficient flagella respond to increased viscosity with contrasting changes in power and recovery strokes.

Wilson KS, Gonzalez O, Dutcher SK, Bayly PV.

Cytoskeleton (Hoboken). 2015 Sep;72(9):477-90. doi: 10.1002/cm.21252. Epub 2015 Sep 16.

41.

Genetic and genomic approaches to identify genes involved in flagellar assembly in Chlamydomonas reinhardtii.

Lin H, Dutcher SK.

Methods Cell Biol. 2015;127:349-86. doi: 10.1016/bs.mcb.2014.12.001. Epub 2015 Feb 14.

42.

Uni-directional ciliary membrane protein trafficking by a cytoplasmic retrograde IFT motor and ciliary ectosome shedding.

Cao M, Ning J, Hernandez-Lara CI, Belzile O, Wang Q, Dutcher SK, Liu Y, Snell WJ.

Elife. 2015 Feb 17;4. doi: 10.7554/eLife.05242.

43.

The ciliary inner dynein arm, I1 dynein, is assembled in the cytoplasm and transported by IFT before axonemal docking.

Viswanadha R, Hunter EL, Yamamoto R, Wirschell M, Alford LM, Dutcher SK, Sale WS.

Cytoskeleton (Hoboken). 2014 Oct;71(10):573-86. doi: 10.1002/cm.21192. Epub 2014 Oct 30.

44.

A Systematic Review of the Benefits and Risks of Anticoagulation Following Traumatic Brain Injury.

Shen X, Dutcher SK, Palmer J, Liu X, Kiptanui Z, Khokhar B, Al-Jawadi MH, Zhu Y, Zuckerman IH.

J Head Trauma Rehabil. 2015 Jul-Aug;30(4):E29-37. doi: 10.1097/HTR.0000000000000077. Review.

45.

Effect of medications on physical function and cognition in nursing home residents with dementia.

Dutcher SK, Rattinger GB, Langenberg P, Chhabra PT, Liu X, Rosenberg PB, Leoutsakos JM, Simoni-Wastila L, Walker LD, Franey CS, Zuckerman IH.

J Am Geriatr Soc. 2014 Jun;62(6):1046-55. doi: 10.1111/jgs.12838. Epub 2014 May 13.

46.

The awesome power of dikaryons for studying flagella and basal bodies in Chlamydomonas reinhardtii.

Dutcher SK.

Cytoskeleton (Hoboken). 2014 Feb;71(2):79-94. doi: 10.1002/cm.21157. Epub 2013 Dec 12. Review.

47.

New mutations in flagellar motors identified by whole genome sequencing in Chlamydomonas.

Lin H, Nauman NP, Albee AJ, Hsu S, Dutcher SK.

Cilia. 2013 Oct 30;2(1):14. doi: 10.1186/2046-2530-2-14.

48.

Site-specific basal body duplication in Chlamydomonas.

O'Toole ET, Dutcher SK.

Cytoskeleton (Hoboken). 2014 Feb;71(2):108-18. doi: 10.1002/cm.21155. Epub 2013 Nov 15.

49.

The Chlamydomonas mutant pf27 reveals novel features of ciliary radial spoke assembly.

Alford LM, Mattheyses AL, Hunter EL, Lin H, Dutcher SK, Sale WS.

Cytoskeleton (Hoboken). 2013 Dec;70(12):804-18. doi: 10.1002/cm.21144.

50.

Whole genome sequencing identifies a deletion in protein phosphatase 2A that affects its stability and localization in Chlamydomonas reinhardtii.

Lin H, Miller ML, Granas DM, Dutcher SK.

PLoS Genet. 2013;9(9):e1003841. doi: 10.1371/journal.pgen.1003841. Epub 2013 Sep 26.

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