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Update on the biology and management of renal cell carcinoma.

Dutcher JP.

J Investig Med. 2018 Nov 18. pii: jim-2018-000918. doi: 10.1136/jim-2018-000918. [Epub ahead of print]


Fundamental science and discoveries at the interface of microbiology and physics.

Dutcher JR.

Can J Microbiol. 2018 Sep;64(9):639-641. doi: 10.1139/cjm-2018-0176. No abstract available.


Interleukin-2 Can Cure Kidney Cancer.

Dutcher JP, Wiernik PH.

Oncologist. 2018 Sep;23(9):e107. doi: 10.1634/theoncologist.2018-0038. Epub 2018 Aug 13. No abstract available.


Unusual polysaccharide rheology of aqueous dispersions of soft phytoglycogen nanoparticles.

Shamana H, Grossutti M, Papp-Szabo E, Miki C, Dutcher JR.

Soft Matter. 2018 Aug 8;14(31):6496-6505. doi: 10.1039/c8sm00815a.


"Pseudoprogression": more than semantics.

Dutcher JP.

Cancer Immunol Immunother. 2018 Sep;67(9):1473-1474. doi: 10.1007/s00262-018-2208-y. Epub 2018 Jul 18. No abstract available.


Behavioral interventions in health neuroscience.

Dutcher JM, Creswell JD.

Ann N Y Acad Sci. 2018 Sep;1428(1):51-70. doi: 10.1111/nyas.13913. Epub 2018 Jun 26. Review.


Pulmonary Langerhans cell histiocytosis, acute myeloid leukemia, and myelofibrosis in a large family and review of the literature.

Blakley MP, Dutcher JP, Wiernik PH.

Leuk Res. 2018 Apr;67:39-44. doi: 10.1016/j.leukres.2018.01.011. Epub 2018 Feb 2.


Supraclavicular Subclavian access for Sapien Transcatheter aortic valve replacement- a novel approach.

Dahle TG, Castro NJ, Stegman BM, Dutcher JR, Teskey JM, Schmidt WT, Danielson DS, Dezell SJ, Daniels VB, Tiede DJ.

J Cardiothorac Surg. 2018 Jan 30;13(1):16. doi: 10.1186/s13019-018-0706-9.


Improved survival and tumor control with Interleukin-2 is associated with the development of immune-related adverse events: data from the PROCLAIMSM registry.

Curti B, Daniels GA, McDermott DF, Clark JI, Kaufman HL, Logan TF, Singh J, Kaur M, Luna TL, Gregory N, Morse MA, Wong MKK, Dutcher JP.

J Immunother Cancer. 2017 Dec 19;5(1):102. doi: 10.1186/s40425-017-0307-5.


A Randomized Phase II Study to Determine the Effect of 2 Different Doses of Aflibercept in Patients With Metastatic Renal Cell Carcinoma (ECOG-ACRIN [E4805]).

Pili R, Jegede O, Carducci MA, Manola J, Groteluschen DL, Appleman LL, Liu G, Shanks JC, Dakhil SR, Dutcher J, DiPaola RS.

Clin Genitourin Cancer. 2017 Dec;15(6):642-651.e1. doi: 10.1016/j.clgc.2017.04.023. Epub 2017 Apr 26.


Adjuvant Treatment for High-Risk Clear Cell Renal Cancer: Updated Results of a High-Risk Subset of the ASSURE Randomized Trial.

Haas NB, Manola J, Dutcher JP, Flaherty KT, Uzzo RG, Atkins MB, DiPaola RS, Choueiri TK.

JAMA Oncol. 2017 Sep 1;3(9):1249-1252. doi: 10.1001/jamaoncol.2017.0076.


Equilibrium Swelling, Interstitial Forces, and Water Structuring in Phytoglycogen Nanoparticle Films.

Grossutti M, Bergmann E, Baylis B, Dutcher JR.

Langmuir. 2017 Mar 21;33(11):2810-2816. doi: 10.1021/acs.langmuir.7b00025. Epub 2017 Mar 10.


Long-Term Response and Possible Cure of Patients With B-Cell Malignancies With Dose-Escalated Rituximab.

Jacobs LM, Wiernik PH, Dutcher JP, Muxi P.

J Investig Med High Impact Case Rep. 2017 Feb 1;5(1):2324709617691307. doi: 10.1177/2324709617691307. eCollection 2017 Jan-Mar.


Impact of Sequencing Targeted Therapies With High-dose Interleukin-2 Immunotherapy: An Analysis of Outcome and Survival of Patients With Metastatic Renal Cell Carcinoma From an On-going Observational IL-2 Clinical Trial: PROCLAIMSM.

Clark JI, Wong MKK, Kaufman HL, Daniels GA, Morse MA, McDermott DF, Agarwala SS, Lewis LD, Stewart JH, Vaishampayan U, Curti B, Gonzalez R, Lutzky J, Rudraptna V, Cranmer LD, Jeter JM, Hauke RJ, Miletello G, Milhem MM, Amin A, Richart JM, Fishman M, Hallmeyer S, Patel SP, Van Veldhuizen P, Agarwal N, Taback B, Treisman JS, Ernstoff MS, Perritt JC, Hua H, Rao TB, Dutcher JP, Aung S.

Clin Genitourin Cancer. 2017 Feb;15(1):31-41.e4. doi: 10.1016/j.clgc.2016.10.008. Epub 2016 Oct 29.


Contemporary experience with high-dose interleukin-2 therapy and impact on survival in patients with metastatic melanoma and metastatic renal cell carcinoma.

Alva A, Daniels GA, Wong MK, Kaufman HL, Morse MA, McDermott DF, Clark JI, Agarwala SS, Miletello G, Logan TF, Hauke RJ, Curti B, Kirkwood JM, Gonzalez R, Amin A, Fishman M, Agarwal N, Lowder JN, Hua H, Aung S, Dutcher JP.

Cancer Immunol Immunother. 2016 Dec;65(12):1533-1544. Epub 2016 Oct 6.


A retrospective analysis of High-Dose Interleukin-2 (HD IL-2) following Ipilimumab in metastatic melanoma.

Buchbinder EI, Gunturi A, Perritt J, Dutcher J, Aung S, Kaufman HL, Ernstoff MS, Miletello GP, Curti BD, Daniels GA, Patel SP, Kirkwood JM, Hallmeyer S, Clark JI, Gonzalez R, Richart JM, Lutzky J, Morse MA, Sullivan RJ, McDermott DF.

J Immunother Cancer. 2016 Sep 20;4:52. doi: 10.1186/s40425-016-0155-8. eCollection 2016.


Occurrence of renal cell carcinoma and hematologic malignancies (predominantly lymphoid) in individuals and in families.

Dutcher JP, Wiernik PH, Varella L, Chintapatla R.

Fam Cancer. 2016 Oct;15(4):677-87. doi: 10.1007/s10689-016-9911-7.


Pure Red Cell Aplasia Following Interleukin-2 Therapy.

Dutcher JP, Fan W, Wiernik PH.

J Investig Med High Impact Case Rep. 2016 Apr 11;4(2):2324709616643991. doi: 10.1177/2324709616643991. eCollection 2016 Apr-Jun.


Oxytocin, but not vasopressin, impairs social cognitive ability among individuals with higher levels of social anxiety: a randomized controlled trial.

Tabak BA, Meyer ML, Dutcher JM, Castle E, Irwin MR, Lieberman MD, Eisenberger NI.

Soc Cogn Affect Neurosci. 2016 Aug;11(8):1272-9. doi: 10.1093/scan/nsw041. Epub 2016 Apr 6.


Exposure to an inflammatory challenge enhances neural sensitivity to negative and positive social feedback.

Muscatell KA, Moieni M, Inagaki TK, Dutcher JM, Jevtic I, Breen EC, Irwin MR, Eisenberger NI.

Brain Behav Immun. 2016 Oct;57:21-29. doi: 10.1016/j.bbi.2016.03.022. Epub 2016 Mar 28.


Adjuvant sunitinib or sorafenib for high-risk, non-metastatic renal-cell carcinoma (ECOG-ACRIN E2805): a double-blind, placebo-controlled, randomised, phase 3 trial.

Haas NB, Manola J, Uzzo RG, Flaherty KT, Wood CG, Kane C, Jewett M, Dutcher JP, Atkins MB, Pins M, Wilding G, Cella D, Wagner L, Matin S, Kuzel TM, Sexton WJ, Wong YN, Choueiri TK, Pili R, Puzanov I, Kohli M, Stadler W, Carducci M, Coomes R, DiPaola RS.

Lancet. 2016 May 14;387(10032):2008-16. doi: 10.1016/S0140-6736(16)00559-6. Epub 2016 Mar 9. Erratum in: Lancet. 2016 May 14;387(10032):1998.


Self-Affirmation Activates the Ventral Striatum: A Possible Reward-Related Mechanism for Self-Affirmation.

Dutcher JM, Creswell JD, Pacilio LE, Harris PR, Klein WM, Levine JM, Bower JE, Muscatell KA, Eisenberger NI.

Psychol Sci. 2016 Apr;27(4):455-66. doi: 10.1177/0956797615625989. Epub 2016 Feb 25.


Structure and Hydration of Highly-Branched, Monodisperse Phytoglycogen Nanoparticles.

Nickels JD, Atkinson J, Papp-Szabo E, Stanley C, Diallo SO, Perticaroli S, Baylis B, Mahon P, Ehlers G, Katsaras J, Dutcher JR.

Biomacromolecules. 2016 Mar 14;17(3):735-43. doi: 10.1021/acs.biomac.5b01393. Epub 2016 Feb 11.


Correlation Between Chain Architecture and Hydration Water Structure in Polysaccharides.

Grossutti M, Dutcher JR.

Biomacromolecules. 2016 Mar 14;17(3):1198-204. doi: 10.1021/acs.biomac.6b00026. Epub 2016 Feb 19.


Effect of Renal Impairment on the Pharmacokinetics and Safety of Axitinib.

Chen Y, Rini BI, Motzer RJ, Dutcher JP, Rixe O, Wilding G, Stadler WM, Tarazi J, Garrett M, Pithavala YK.

Target Oncol. 2016 Apr;11(2):229-34. doi: 10.1007/s11523-015-0389-2.


Links between inflammation, amygdala reactivity, and social support in breast cancer survivors.

Muscatell KA, Eisenberger NI, Dutcher JM, Cole SW, Bower JE.

Brain Behav Immun. 2016 Mar;53:34-38. doi: 10.1016/j.bbi.2015.09.008. Epub 2015 Sep 15.


Effect of Skin-to-Skin Holding on Stress in Mothers of Late-Preterm Infants: A Randomized Controlled Trial.

Samra HA, Dutcher J, McGrath JM, Foster M, Klein L, Djira G, Hansen J, Wallenburg D.

Adv Neonatal Care. 2015 Oct;15(5):354-64. doi: 10.1097/ANC.0000000000000223.


Renal cell carcinoma in patients with a personal or family history of hematologic malignancies.

Dutcher JP, Wiernik PH.

Clin Adv Hematol Oncol. 2015 Jun;13(6):392-7.


Families with both Hodgkin lymphoma and multiple myeloma in their pedigrees.

Wiernik PH, Wickramasinghe D, Dutcher JP.

Clin Adv Hematol Oncol. 2015 Apr;13(4):257-60.


Proteome Profiles of Outer Membrane Vesicles and Extracellular Matrix of Pseudomonas aeruginosa Biofilms.

Couto N, Schooling SR, Dutcher JR, Barber J.

J Proteome Res. 2015 Oct 2;14(10):4207-22. doi: 10.1021/acs.jproteome.5b00312. Epub 2015 Sep 15.


Atrasentan in Patients With Advanced Renal Cell Carcinoma: A Phase 2 Trial of the ECOG-ACRIN Cancer Research Group (E6800).

Carducci MA, Manola J, Nair SG, Liu G, Rousey S, Dutcher JP, Wilding G.

Clin Genitourin Cancer. 2015 Dec;13(6):531-539.e1. doi: 10.1016/j.clgc.2015.07.002. Epub 2015 Jul 17.


Yearning for connection? Loneliness is associated with increased ventral striatum activity to close others.

Inagaki TK, Muscatell KA, Moieni M, Dutcher JM, Jevtic I, Irwin MR, Eisenberger NI.

Soc Cogn Affect Neurosci. 2016 Jul;11(7):1096-101. doi: 10.1093/scan/nsv076. Epub 2015 Jun 17.


Nanoscale Pulling of Type IV Pili Reveals Their Flexibility and Adhesion to Surfaces over Extended Lengths of the Pili.

Lu S, Giuliani M, Harvey H, Burrows LL, Wickham RA, Dutcher JR.

Biophys J. 2015 Jun 16;108(12):2865-75. doi: 10.1016/j.bpj.2015.05.016.


Effects of Adjuvant Sorafenib and Sunitinib on Cardiac Function in Renal Cell Carcinoma Patients without Overt Metastases: Results from ASSURE, ECOG 2805.

Haas NB, Manola J, Ky B, Flaherty KT, Uzzo RG, Kane CJ, Jewett M, Wood L, Wood CG, Atkins MB, Dutcher JJ, Wilding G, DiPaola RS.

Clin Cancer Res. 2015 Sep 15;21(18):4048-54. doi: 10.1158/1078-0432.CCR-15-0215. Epub 2015 May 12.


The NICU Parent Risk Evaluation and Engagement Model and Instrument (PREEMI) for neonates in intensive care units.

Samra HA, McGrath JM, Fischer S, Schumacher B, Dutcher J, Hansen J.

J Obstet Gynecol Neonatal Nurs. 2015 Jan-Feb;44(1):114-126. doi: 10.1111/1552-6909.12535. Epub 2015 Jan 7.


Vasopressin, but not oxytocin, increases empathic concern among individuals who received higher levels of paternal warmth: A randomized controlled trial.

Tabak BA, Meyer ML, Castle E, Dutcher JM, Irwin MR, Han JH, Lieberman MD, Eisenberger NI.

Psychoneuroendocrinology. 2015 Jan;51:253-61. doi: 10.1016/j.psyneuen.2014.10.006. Epub 2014 Oct 17.


The role of the ventral striatum in inflammatory-induced approach toward support figures.

Inagaki TK, Muscatell KA, Irwin MR, Moieni M, Dutcher JM, Jevtic I, Breen EC, Eisenberger NI.

Brain Behav Immun. 2015 Feb;44:247-52. doi: 10.1016/j.bbi.2014.10.006. Epub 2014 Oct 16.


The high-dose aldesleukin "select" trial: a trial to prospectively validate predictive models of response to treatment in patients with metastatic renal cell carcinoma.

McDermott DF, Cheng SC, Signoretti S, Margolin KA, Clark JI, Sosman JA, Dutcher JP, Logan TF, Curti BD, Ernstoff MS, Appleman L, Wong MK, Khushalani NI, Oleksowicz L, Vaishampayan UN, Mier JW, Panka DJ, Bhatt RS, Bailey AS, Leibovich BC, Kwon ED, Kabbinavar FF, Belldegrun AS, Figlin RA, Pantuck AJ, Regan MM, Atkins MB.

Clin Cancer Res. 2015 Feb 1;21(3):561-8. doi: 10.1158/1078-0432.CCR-14-1520. Epub 2014 Nov 25.


A phase I study of cabozantinib (XL184) in patients with renal cell cancer.

Choueiri TK, Pal SK, McDermott DF, Morrissey S, Ferguson KC, Holland J, Kaelin WG, Dutcher JP.

Ann Oncol. 2014 Aug;25(8):1603-8. doi: 10.1093/annonc/mdu184. Epub 2014 May 14.


Nanomechanical response of bacterial cells to cationic antimicrobial peptides.

Lu S, Walters G, Parg R, Dutcher JR.

Soft Matter. 2014 Mar 21;10(11):1806-15. doi: 10.1039/c3sm52801d.


Advances in surface plasmon resonance imaging enable quantitative tracking of nanoscale changes in thickness and roughness.

Raegen AN, Reiter K, Dion A, Clarke AJ, Lipkowski J, Dutcher JR.

Anal Chem. 2014 Apr 1;86(7):3346-54. doi: 10.1021/ac4034664. Epub 2014 Mar 19.


The effect of nanoscale surface curvature on the oligomerization of surface-bound proteins.

Kurylowicz M, Paulin H, Mogyoros J, Giuliani M, Dutcher JR.

J R Soc Interface. 2014 Feb 26;11(94):20130818. doi: 10.1098/rsif.2013.0818. Print 2014 May 6.


Report of a phase I evaluation of dose and schedule of interleukin-1 alpha and cyclophosphamide in patients with advanced tumors: An Eastern Cooperative Oncology Group study (PX990) and review of IL-1-based studies of hematopoietic reconstitution.

Dutcher JP, Neuberg D, Atkins MB, Tester WJ, Wadler S, Stewart JA, Chachoua A, Schuchter LM.

J Interferon Cytokine Res. 2014 May;34(5):376-84. doi: 10.1089/jir.2013.0010. Epub 2014 Jan 16.


Recent developments in the treatment of renal cell carcinoma.

Dutcher JP.

Ther Adv Urol. 2013 Dec;5(6):338-53. doi: 10.1177/1756287213505672. Review.


Direct in situ observation of synergism between cellulolytic enzymes during the biodegradation of crystalline cellulose fibers.

Wang J, Quirk A, Lipkowski J, Dutcher JR, Clarke AJ.

Langmuir. 2013 Dec 3;29(48):14997-5005. doi: 10.1021/la403401c. Epub 2013 Nov 19.


A phase II study of bevacizumab and high-dose interleukin-2 in patients with metastatic renal cell carcinoma: a Cytokine Working Group (CWG) study.

Dandamudi UB, Ghebremichael M, Sosman JA, Clark JI, McDermott DF, Atkins MB, Dutcher JP, Urba WJ, Regan MM, Puzanov I, Crocenzi TS, Curti BD, Vaishampayan UN, Crosby NA, Margolin KA, Ernstoff MS.

J Immunother. 2013 Nov-Dec;36(9):490-5. doi: 10.1097/CJI.0000000000000003.


Classic case of unicentric mixed-type Castleman's disease.

Nagubandi R, Wang Y, Dutcher JP, Rao PM.

J Clin Oncol. 2013 Dec 20;31(36):e452-5. doi: 10.1200/JCO.2012.45.9941. Epub 2013 Oct 14. No abstract available.


Self-affirmation improves problem-solving under stress.

Creswell JD, Dutcher JM, Klein WM, Harris PR, Levine JM.

PLoS One. 2013 May 1;8(5):e62593. doi: 10.1371/journal.pone.0062593. Print 2013.


Targeted therapies and the treatment of non-clear cell renal cell carcinoma.

Bellmunt J, Dutcher J.

Ann Oncol. 2013 Jul;24(7):1730-40. doi: 10.1093/annonc/mdt152. Epub 2013 Apr 26. Review.


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