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Items: 1 to 50 of 319

1.

The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis.

Mintz MA, Felce JH, Chou MY, Mayya V, Xu Y, Shui JW, An J, Li Z, Marson A, Okada T, Ware CF, Kronenberg M, Dustin ML, Cyster JG.

Immunity. 2019 Jun 10. pii: S1074-7613(19)30242-0. doi: 10.1016/j.immuni.2019.05.022. [Epub ahead of print]

2.

Cutting Edge: Synapse Propensity of Human Memory CD8 T Cells Confers Competitive Advantage over Naive Counterparts.

Mayya V, Judokusumo E, Abu-Shah E, Neiswanger W, Sachar C, Depoil D, Kam LC, Dustin ML.

J Immunol. 2019 Jun 14. pii: ji1801687. doi: 10.4049/jimmunol.1801687. [Epub ahead of print]

PMID:
31201237
3.

An X-ray Vision for Phosphoantigen Recognition.

Dustin ML, Scotet E, Olive D.

Immunity. 2019 Apr 16;50(4):1026-1028. doi: 10.1016/j.immuni.2019.03.015.

PMID:
30995494
4.

Integrins and Their Role in Immune Cell Adhesion.

Dustin ML.

Cell. 2019 Apr 18;177(3):499-501. doi: 10.1016/j.cell.2019.03.038. Epub 2019 Apr 2.

PMID:
30952447
5.

Retraction: Steering CAR T Cells into Solid Tumors. N Engl J Med 2019;380:289-91.

Brown MH, Dustin ML.

N Engl J Med. 2019 Mar 28;380(13):1286. doi: 10.1056/NEJMc1902526. Epub 2019 Feb 20. No abstract available.

6.

Immunophenotypes of pancreatic ductal adenocarcinoma: Meta-analysis of transcriptional subtypes.

de Santiago I, Yau C, Heij L, Middleton MR, Markowetz F, Grabsch HI, Dustin ML, Sivakumar S.

Int J Cancer. 2019 Aug 15;145(4):1125-1137. doi: 10.1002/ijc.32186. Epub 2019 Mar 18.

7.

Steering CAR T Cells into Solid Tumors.

Brown MH, Dustin ML.

N Engl J Med. 2019 Jan 17;380(3):289-291. doi: 10.1056/NEJMcibr1811991. No abstract available. Retraction in: N Engl J Med. 2019 Mar 28;380(13):1286.

8.

CD45 exclusion- and cross-linking-based receptor signaling together broaden FcεRI reactivity.

Felce JH, Sezgin E, Wane M, Brouwer H, Dustin ML, Eggeling C, Davis SJ.

Sci Signal. 2018 Dec 18;11(561). pii: eaat0756. doi: 10.1126/scisignal.aat0756.

PMID:
30563863
9.

Dendritic cell-expressed common gamma-chain recruits IL-15 for trans-presentation at the murine immunological synapse.

Beilin C, Choudhuri K, Bouma G, Malinova D, Llodra J, Stokes DL, Shimaoka M, Springer TA, Dustin ML, Thrasher AJ, Burns SO.

Version 2. Wellcome Open Res. 2018 Oct 17 [revised 2018 Jan 1];3:84. doi: 10.12688/wellcomeopenres.14493.2. eCollection 2018.

10.

CD8 helps TCR catch slippery self pMHC.

Dushek O, Dustin ML.

Nat Immunol. 2018 Dec;19(12):1280-1281. doi: 10.1038/s41590-018-0261-5. No abstract available.

PMID:
30420625
11.

Tumor Necrosis Factor Receptor Superfamily in T Cell Priming and Effector Function.

Muller J, Baeyens A, Dustin ML.

Adv Immunol. 2018;140:21-57. doi: 10.1016/bs.ai.2018.08.001. Epub 2018 Sep 17.

PMID:
30366518
12.

Reconstitution of immune cell interactions in free-standing membranes.

Jenkins E, Santos AM, O'Brien-Ball C, Felce JH, Wilcock MJ, Hatherley D, Dustin ML, Davis SJ, Eggeling C, Sezgin E.

J Cell Sci. 2018 Oct 2;132(4). pii: jcs219709. doi: 10.1242/jcs.219709.

13.

The Study of Platelet Receptors Using Artificial Lipid Bilayers.

Dustin ML, Pollitt AY.

Methods Mol Biol. 2018;1812:127-137. doi: 10.1007/978-1-4939-8585-2_8.

PMID:
30171576
14.

Natural killers shed attachments to kill again.

Felce JH, Dustin ML.

J Cell Biol. 2018 Sep 3;217(9):2983-2985. doi: 10.1083/jcb.201807105. Epub 2018 Aug 14.

15.

The vimentin intermediate filament network restrains regulatory T cell suppression of graft-versus-host disease.

McDonald-Hyman C, Muller JT, Loschi M, Thangavelu G, Saha A, Kumari S, Reichenbach DK, Smith MJ, Zhang G, Koehn BH, Lin J, Mitchell JS, Fife BT, Panoskaltsis-Mortari A, Feser CJ, Kirchmeier AK, Osborn MJ, Hippen KL, Kelekar A, Serody JS, Turka LA, Munn DH, Chi H, Neubert TA, Dustin ML, Blazar BR.

J Clin Invest. 2018 Oct 1;128(10):4604-4621. doi: 10.1172/JCI95713. Epub 2018 Aug 14.

16.

F-Actin-Driven CD28-CD80 Localization in the Immune Synapse.

Siokis A, Robert PA, Demetriou P, Dustin ML, Meyer-Hermann M.

Cell Rep. 2018 Jul 31;24(5):1151-1162. doi: 10.1016/j.celrep.2018.06.114.

17.

Protein tyrosine phosphatase PTPN22 regulates LFA-1 dependent Th1 responses.

Sanchez-Blanco C, Clarke F, Cornish GH, Depoil D, Thompson SJ, Dai X, Rawlings DJ, Dustin ML, Zamoyska R, Cope AP, Purvis HA.

J Autoimmun. 2018 Nov;94:45-55. doi: 10.1016/j.jaut.2018.07.008. Epub 2018 Jul 24.

18.

Maintenance of CD4 T cell fitness through regulation of Foxo1.

Newton RH, Shrestha S, Sullivan JM, Yates KB, Compeer EB, Ron-Harel N, Blazar BR, Bensinger SJ, Haining WN, Dustin ML, Campbell DJ, Chi H, Turka LA.

Nat Immunol. 2018 Aug;19(8):838-848. doi: 10.1038/s41590-018-0157-4. Epub 2018 Jul 9.

PMID:
29988091
19.

Distinct behavior of myelomonocytic cells and CD8 T cells underlies the hepatic response to Listeria monocytogenes.

Velázquez P, Williams C, Leiner I, Pamer EG, Dustin ML.

Wellcome Open Res. 2018 Apr 24;3:48. doi: 10.12688/wellcomeopenres.12941.1. eCollection 2018.

20.

Full control of ligand positioning reveals spatial thresholds for T cell receptor triggering.

Cai H, Muller J, Depoil D, Mayya V, Sheetz MP, Dustin ML, Wind SJ.

Nat Nanotechnol. 2018 Jul;13(7):610-617. doi: 10.1038/s41565-018-0113-3. Epub 2018 Apr 30.

21.

Capturing resting T cells: the perils of PLL.

Santos AM, Ponjavic A, Fritzsche M, Fernandes RA, de la Serna JB, Wilcock MJ, Schneider F, Urbančič I, McColl J, Anzilotti C, Ganzinger KA, Aßmann M, Depoil D, Cornall RJ, Dustin ML, Klenerman D, Davis SJ, Eggeling C, Lee SF.

Nat Immunol. 2018 Mar;19(3):203-205. doi: 10.1038/s41590-018-0048-8. Epub 2018 Feb 23. No abstract available.

PMID:
29476188
22.

A Stretch of Negatively Charged Amino Acids of Linker for Activation of T-Cell Adaptor Has a Dual Role in T-Cell Antigen Receptor Intracellular Signaling.

Arbulo-Echevarria MM, Narbona-Sánchez I, Fernandez-Ponce CM, Vico-Barranco I, Rueda-Ygueravide MD, Dustin ML, Miazek A, Duran-Ruiz MC, García-Cózar F, Aguado E.

Front Immunol. 2018 Feb 2;9:115. doi: 10.3389/fimmu.2018.00115. eCollection 2018.

23.

Durable Interactions of T Cells with T Cell Receptor Stimuli in the Absence of a Stable Immunological Synapse.

Mayya V, Judokusumo E, Abu Shah E, Peel CG, Neiswanger W, Depoil D, Blair DA, Wiggins CH, Kam LC, Dustin ML.

Cell Rep. 2018 Jan 9;22(2):340-349. doi: 10.1016/j.celrep.2017.12.052.

24.

The tyrosine phosphatase SHP-1 promotes T cell adhesion by activating the adaptor protein CrkII in the immunological synapse.

Azoulay-Alfaguter I, Strazza M, Peled M, Novak HK, Muller J, Dustin ML, Mor A.

Sci Signal. 2017 Aug 8;10(491). pii: eaal2880. doi: 10.1126/scisignal.aal2880.

PMID:
28790195
25.

Crosstalk between Regulatory T Cells and Tumor-Associated Dendritic Cells Negates Anti-tumor Immunity in Pancreatic Cancer.

Jang JE, Hajdu CH, Liot C, Miller G, Dustin ML, Bar-Sagi D.

Cell Rep. 2017 Jul 18;20(3):558-571. doi: 10.1016/j.celrep.2017.06.062.

26.

TFH-derived dopamine accelerates productive synapses in germinal centres.

Papa I, Saliba D, Ponzoni M, Bustamante S, Canete PF, Gonzalez-Figueroa P, McNamara HA, Valvo S, Grimbaldeston M, Sweet RA, Vohra H, Cockburn IA, Meyer-Hermann M, Dustin ML, Doglioni C, Vinuesa CG.

Nature. 2017 Jul 20;547(7663):318-323. doi: 10.1038/nature23013. Epub 2017 Jul 12.

27.

Human in vitro-induced regulatory T cells display Dlgh1dependent and PKC-θ restrained suppressive activity.

Zanin-Zhorov A, Kumari S, Hippen KL, Merkel SC, MacMillan ML, Blazar BR, Dustin ML.

Sci Rep. 2017 Jun 26;7(1):4258. doi: 10.1038/s41598-017-04053-5.

28.

Lymphatic endothelial S1P promotes mitochondrial function and survival in naive T cells.

Mendoza A, Fang V, Chen C, Serasinghe M, Verma A, Muller J, Chaluvadi VS, Dustin ML, Hla T, Elemento O, Chipuk JE, Schwab SR.

Nature. 2017 Jun 1;546(7656):158-161. doi: 10.1038/nature22352. Epub 2017 May 24.

29.

Localizing order to boost signaling.

Bálint Š, Dustin ML.

Elife. 2017 Mar 30;6. pii: e25375. doi: 10.7554/eLife.25375.

30.

Membrane nanoclusters of FcγRI segregate from inhibitory SIRPα upon activation of human macrophages.

Lopes FB, Bálint Š, Valvo S, Felce JH, Hessel EM, Dustin ML, Davis DM.

J Cell Biol. 2017 Apr 3;216(4):1123-1141. doi: 10.1083/jcb.201608094. Epub 2017 Mar 13.

31.

Comprehensive Analysis of Immunological Synapse Phenotypes Using Supported Lipid Bilayers.

Valvo S, Mayya V, Seraia E, Afrose J, Novak-Kotzer H, Ebner D, Dustin ML.

Methods Mol Biol. 2017;1584:423-441. doi: 10.1007/978-1-4939-6881-7_26.

PMID:
28255717
32.

Spatial Control of Biological Ligands on Surfaces Applied to T Cell Activation.

Cai H, Depoil D, Muller J, Sheetz MP, Dustin ML, Wind SJ.

Methods Mol Biol. 2017;1584:307-331. doi: 10.1007/978-1-4939-6881-7_18.

PMID:
28255709
33.

The Immune Synapse: Past, Present, and Future.

Dustin ML, Baldari CT.

Methods Mol Biol. 2017;1584:1-5. doi: 10.1007/978-1-4939-6881-7_1. Review.

PMID:
28255692
34.

Dynamin-2 Stabilizes the HIV-1 Fusion Pore with a Low Oligomeric State.

Jones DM, Alvarez LA, Nolan R, Ferriz M, Sainz Urruela R, Massana-Muñoz X, Novak-Kotzer H, Dustin ML, Padilla-Parra S.

Cell Rep. 2017 Jan 10;18(2):443-453. doi: 10.1016/j.celrep.2016.12.032.

35.

Foxo4- and Stat3-dependent IL-10 production by progranulin in regulatory T cells restrains inflammatory arthritis.

Fu W, Hu W, Shi L, Mundra JJ, Xiao G, Dustin ML, Liu CJ.

FASEB J. 2017 Apr;31(4):1354-1367. doi: 10.1096/fj.201601134R. Epub 2016 Dec 23.

36.

Help to go: T cells transfer CD40L to antigen-presenting B cells.

Dustin ML.

Eur J Immunol. 2017 Jan;47(1):31-34. doi: 10.1002/eji.201646786. Epub 2016 Dec 22.

37.

Size-dependent protein segregation at membrane interfaces.

Schmid EM, Bakalar MH, Choudhuri K, Weichsel J, Ann H, Geissler PL, Dustin ML, Fletcher DA.

Nat Phys. 2016 Jul;12(7):704-711. Epub 2016 Mar 7.

38.

Complement Receptors in Myeloid Cell Adhesion and Phagocytosis.

Dustin ML.

Microbiol Spectr. 2016 Nov;4(6). doi: 10.1128/microbiolspec.MCHD-0034-2016. Review.

39.

Actin polymerization-dependent activation of Cas-L promotes immunological synapse stability.

Santos LC, Blair DA, Kumari S, Cammer M, Iskratsch T, Herbin O, Alexandropoulos K, Dustin ML, Sheetz MP.

Immunol Cell Biol. 2016 Nov;94(10):981-993. doi: 10.1038/icb.2016.61. Epub 2016 Jun 30.

40.

HIV Envelope gp120 Alters T Cell Receptor Mobilization in the Immunological Synapse of Uninfected CD4 T Cells and Augments T Cell Activation.

Deng J, Mitsuki YY, Shen G, Ray JC, Cicala C, Arthos J, Dustin ML, Hioe CE.

J Virol. 2016 Nov 14;90(23):10513-10526. doi: 10.1128/JVI.01532-16. Print 2016 Dec 1.

41.

Force Bistability in Adhesion Switch.

Dustin ML, Peel CG.

Biophys J. 2016 Sep 6;111(5):900-1. doi: 10.1016/j.bpj.2016.07.031. No abstract available.

42.

γδ T Cells Support Pancreatic Oncogenesis by Restraining αβ T Cell Activation.

Daley D, Zambirinis CP, Seifert L, Akkad N, Mohan N, Werba G, Barilla R, Torres-Hernandez A, Hundeyin M, Mani VRK, Avanzi A, Tippens D, Narayanan R, Jang JE, Newman E, Pillarisetty VG, Dustin ML, Bar-Sagi D, Hajdu C, Miller G.

Cell. 2016 Sep 8;166(6):1485-1499.e15. doi: 10.1016/j.cell.2016.07.046. Epub 2016 Aug 25.

43.

Mitochondrial fusion fuels T cell memory.

Lanna A, Dustin ML.

Cell Res. 2016 Sep;26(9):969-70. doi: 10.1038/cr.2016.94. Epub 2016 Aug 12.

44.

Signaling and Polarized Communication Across the T Cell Immunological Synapse.

Dustin ML, Choudhuri K.

Annu Rev Cell Dev Biol. 2016 Oct 6;32:303-325. Epub 2016 Aug 3. Review.

PMID:
27501450
45.

Immune dysregulation in patients with PTEN hamartoma tumor syndrome: Analysis of FOXP3 regulatory T cells.

Chen HH, Händel N, Ngeow J, Muller J, Hühn M, Yang HT, Heindl M, Berbers RM, Hegazy AN, Kionke J, Yehia L, Sack U, Bläser F, Rensing-Ehl A, Reifenberger J, Keith J, Travis S, Merkenschlager A, Kiess W, Wittekind C, Walker L, Ehl S, Aretz S, Dustin ML, Eng C, Powrie F, Uhlig HH.

J Allergy Clin Immunol. 2017 Feb;139(2):607-620.e15. doi: 10.1016/j.jaci.2016.03.059. Epub 2016 Jun 18.

46.

What Scales the T Cell Response?

Mayya V, Dustin ML.

Trends Immunol. 2016 Aug;37(8):513-522. doi: 10.1016/j.it.2016.06.005. Epub 2016 Jun 27. Review.

PMID:
27364960
47.

Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality.

Saha A, O'Connor RS, Thangavelu G, Lovitch SB, Dandamudi DB, Wilson CB, Vincent BG, Tkachev V, Pawlicki JM, Furlan SN, Kean LS, Aoyama K, Taylor PA, Panoskaltsis-Mortari A, Foncea R, Ranganathan P, Devine SM, Burrill JS, Guo L, Sacristan C, Snyder NW, Blair IA, Milone MC, Dustin ML, Riley JL, Bernlohr DA, Murphy WJ, Fife BT, Munn DH, Miller JS, Serody JS, Freeman GJ, Sharpe AH, Turka LA, Blazar BR.

J Clin Invest. 2016 Jul 1;126(7):2642-60. doi: 10.1172/JCI85796. Epub 2016 Jun 13.

48.

Tapping out a mechanical code for T cell triggering.

Dustin ML, Kam LC.

J Cell Biol. 2016 Jun 6;213(5):501-3. doi: 10.1083/jcb.201605072.

49.

Actin Dynamics and HIV-1 Entry.

Padilla-Parra S, Dustin ML.

Trends Mol Med. 2016 May;22(5):354-356. doi: 10.1016/j.molmed.2016.03.007. Epub 2016 Apr 14.

PMID:
27151391
50.

CELL SIGNALING. Liquidity in immune cell signaling.

Dustin ML, Muller J.

Science. 2016 Apr 29;352(6285):516-7. doi: 10.1126/science.aaf8179. No abstract available.

PMID:
27126023

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