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Items: 39


An HCV vaccine on the fly.

Laidlaw SM, Dustin LB.

J Infect Dis. 2019 May 10. pii: jiz231. doi: 10.1093/infdis/jiz231. [Epub ahead of print] No abstract available.


Tumor Necrosis Factor Inhibits Spread of Hepatitis C Virus Among Liver Cells, Independent From Interferons.

Laidlaw SM, Marukian S, Gilmore RH, Cashman SB, Nechyporuk-Zloy V, Rice CM, Dustin LB.

Gastroenterology. 2017 Aug;153(2):566-578.e5. doi: 10.1053/j.gastro.2017.04.021. Epub 2017 Apr 26.


Hepatitis C virus: life cycle in cells, infection and host response, and analysis of molecular markers influencing the outcome of infection and response to therapy.

Dustin LB, Bartolini B, Capobianchi MR, Pistello M.

Clin Microbiol Infect. 2016 Oct;22(10):826-832. doi: 10.1016/j.cmi.2016.08.025. Epub 2016 Aug 31. Review.


MAIT cells are activated during human viral infections.

van Wilgenburg B, Scherwitzl I, Hutchinson EC, Leng T, Kurioka A, Kulicke C, de Lara C, Cole S, Vasanawathana S, Limpitikul W, Malasit P, Young D, Denney L; STOP-HCV consortium, Moore MD, Fabris P, Giordani MT, Oo YH, Laidlaw SM, Dustin LB, Ho LP, Thompson FM, Ramamurthy N, Mongkolsapaya J, Willberg CB, Screaton GR, Klenerman P.

Nat Commun. 2016 Jun 23;7:11653. doi: 10.1038/ncomms11653.


Editorial: Recent Advances in HBV and HCV Immunology.

Dustin LB, Trehanpati N.

Front Immunol. 2015 Sep 4;6:453. doi: 10.3389/fimmu.2015.00453. eCollection 2015. No abstract available.


Innate and Adaptive Immune Responses in Chronic HCV Infection.

Dustin LB.

Curr Drug Targets. 2017;18(7):826-843. doi: 10.2174/1389450116666150825110532. Review.


The Humoral Immune Response to HCV: Understanding is Key to Vaccine Development.

Cashman SB, Marsden BD, Dustin LB.

Front Immunol. 2014 Nov 10;5:550. doi: 10.3389/fimmu.2014.00550. eCollection 2014. Review.


Interferon lambda: opportunities, risks, and uncertainties in the fight against HCV.

Laidlaw SM, Dustin LB.

Front Immunol. 2014 Oct 31;5:545. doi: 10.3389/fimmu.2014.00545. eCollection 2014. Review.


Genome-wide association study of hepatitis C virus- and cryoglobulin-related vasculitis.

Zignego AL, Wojcik GL, Cacoub P, Visentini M, Casato M, Mangia A, Latanich R, Charles ED, Gragnani L, Terrier B, Piazzola V, Dustin LB, Khakoo SI, Busch MP, Lauer GM, Kim AY, Alric L, Thomas DL, Duggal P.

Genes Immun. 2014 Oct;15(7):500-5. doi: 10.1038/gene.2014.41. Epub 2014 Jul 17.


Immune control and failure in HCV infection--tipping the balance.

Dustin LB, Cashman SB, Laidlaw SM.

J Leukoc Biol. 2014 Oct;96(4):535-48. doi: 10.1189/jlb.4RI0214-126R. Epub 2014 Jul 11. Review.


Selection of apoptotic cell specific human antibodies from adult bone marrow.

Grönwall C, Charles ED, Dustin LB, Rader C, Silverman GJ.

PLoS One. 2014 Apr 23;9(4):e95999. doi: 10.1371/journal.pone.0095999. eCollection 2014.


Immunotherapy of chronic hepatitis C virus infection with antibodies against programmed cell death-1 (PD-1).

Fuller MJ, Callendret B, Zhu B, Freeman GJ, Hasselschwert DL, Satterfield W, Sharpe AH, Dustin LB, Rice CM, Grakoui A, Ahmed R, Walker CM.

Proc Natl Acad Sci U S A. 2013 Sep 10;110(37):15001-6. doi: 10.1073/pnas.1312772110. Epub 2013 Aug 26.


Somatic hypermutations confer rheumatoid factor activity in hepatitis C virus-associated mixed cryoglobulinemia.

Charles ED, Orloff MI, Nishiuchi E, Marukian S, Rice CM, Dustin LB.

Arthritis Rheum. 2013 Sep;65(9):2430-40. doi: 10.1002/art.38041.


Primary, post-primary and non-specific immunoglobulin M responses in HCV infection.

Dustin LB, Charles ED.

Antivir Ther. 2012;17(7 Pt B):1449-52. doi: 10.3851/IMP2222. Epub 2012 Dec 7. Review.


Efficient replication of genotype 3a and 4a hepatitis C virus replicons in human hepatoma cells.

Saeed M, Scheel TK, Gottwein JM, Marukian S, Dustin LB, Bukh J, Rice CM.

Antimicrob Agents Chemother. 2012 Oct;56(10):5365-73. doi: 10.1128/AAC.01256-12. Epub 2012 Aug 6.


Too low to measure, infectious nonetheless.

Dustin LB.

Blood. 2012 Jun 28;119(26):6181-2. doi: 10.1182/blood-2012-04-425272. No abstract available.


Interferon α-stimulated natural killer cells from patients with acute hepatitis C virus (HCV) infection recognize HCV-infected and uninfected hepatoma cells via DNAX accessory molecule-1.

Stegmann KA, Björkström NK, Ciesek S, Lunemann S, Jaroszewicz J, Wiegand J, Malinski P, Dustin LB, Rice CM, Manns MP, Pietschmann T, Cornberg M, Ljunggren HG, Wedemeyer H.

J Infect Dis. 2012 May 1;205(9):1351-62. doi: 10.1093/infdis/jis210. Epub 2012 Mar 29.


Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells.

Andrus L, Marukian S, Jones CT, Catanese MT, Sheahan TP, Schoggins JW, Barry WT, Dustin LB, Trehan K, Ploss A, Bhatia SN, Rice CM.

Hepatology. 2011 Dec;54(6):1901-12. doi: 10.1002/hep.24557.


Hepatitis C virus induces interferon-λ and interferon-stimulated genes in primary liver cultures.

Marukian S, Andrus L, Sheahan TP, Jones CT, Charles ED, Ploss A, Rice CM, Dustin LB.

Hepatology. 2011 Dec;54(6):1913-23. doi: 10.1002/hep.24580.


Clonal B cells in patients with hepatitis C virus-associated mixed cryoglobulinemia contain an expanded anergic CD21low B-cell subset.

Charles ED, Brunetti C, Marukian S, Ritola KD, Talal AH, Marks K, Jacobson IM, Rice CM, Dustin LB.

Blood. 2011 May 19;117(20):5425-37. doi: 10.1182/blood-2010-10-312942. Epub 2011 Mar 18.


Chemokine antagonism in chronic hepatitis C virus infection.

Charles ED, Dustin LB.

J Clin Invest. 2011 Jan;121(1):25-7. doi: 10.1172/JCI45610. Epub 2010 Dec 22.


A flow cytometry-based strategy to identify and express IgM from VH1-69+ clonal peripheral B cells.

Charles ED, Orloff MI, Dustin LB.

J Immunol Methods. 2011 Jan 5;363(2):210-20. doi: 10.1016/j.jim.2010.09.022. Epub 2010 Sep 24.


Hepatitis C virus-induced cryoglobulinemia.

Charles ED, Dustin LB.

Kidney Int. 2009 Oct;76(8):818-24. doi: 10.1038/ki.2009.247. Epub 2009 Jul 15. Review.


Cell culture-produced hepatitis C virus does not infect peripheral blood mononuclear cells.

Marukian S, Jones CT, Andrus L, Evans MJ, Ritola KD, Charles ED, Rice CM, Dustin LB.

Hepatology. 2008 Dec;48(6):1843-50. doi: 10.1002/hep.22550.


Clonal expansion of immunoglobulin M+CD27+ B cells in HCV-associated mixed cryoglobulinemia.

Charles ED, Green RM, Marukian S, Talal AH, Lake-Bakaar GV, Jacobson IM, Rice CM, Dustin LB.

Blood. 2008 Feb 1;111(3):1344-56. Epub 2007 Oct 17.


Flying under the radar: the immunobiology of hepatitis C.

Dustin LB, Rice CM.

Annu Rev Immunol. 2007;25:71-99. Review.


Interferon (IFN)-gamma-inducible protein-10: association with histological results, viral kinetics, and outcome during treatment with pegylated IFN-alpha 2a and ribavirin for chronic hepatitis C virus infection.

Romero AI, Lagging M, Westin J, Dhillon AP, Dustin LB, Pawlotsky JM, Neumann AU, Ferrari C, Missale G, Haagmans BL, Schalm SW, Zeuzem S, Negro F, Verheij-Hart E, Hellstrand K; DITTO-HCV Study Group.

J Infect Dis. 2006 Oct 1;194(7):895-903. Epub 2006 Aug 29.


Plasma chemokine levels correlate with the outcome of antiviral therapy in patients with hepatitis C.

Butera D, Marukian S, Iwamaye AE, Hembrador E, Chambers TJ, Di Bisceglie AM, Charles ED, Talal AH, Jacobson IM, Rice CM, Dustin LB.

Blood. 2005 Aug 15;106(4):1175-82. Epub 2005 Apr 28.


Quasispecies heterogeneity within the E1/E2 region as a pretreatment variable during pegylated interferon therapy of chronic hepatitis C virus infection.

Chambers TJ, Fan X, Droll DA, Hembrador E, Slater T, Nickells MW, Dustin LB, Dibisceglie AM.

J Virol. 2005 Mar;79(5):3071-83.


Reexamining the role of the humoral immune response in control of hepatitis C virus infection.

Dustin LB.

Hepatology. 2004 Sep;40(3):756-8. No abstract available.


Diverse hepatitis C virus glycoproteins mediate viral infection in a CD81-dependent manner.

McKeating JA, Zhang LQ, Logvinoff C, Flint M, Zhang J, Yu J, Butera D, Ho DD, Dustin LB, Rice CM, Balfe P.

J Virol. 2004 Aug;78(16):8496-505.


Accumulation of B lymphocytes with a naive, resting phenotype in a subset of hepatitis C patients.

Ni J, Hembrador E, Di Bisceglie AM, Jacobson IM, Talal AH, Butera D, Rice CM, Chambers TJ, Dustin LB.

J Immunol. 2003 Mar 15;170(6):3429-39.


The immunological relay race: B cells take antigen by synapse.

Dustin ML, Dustin LB.

Nat Immunol. 2001 Jun;2(6):480-2. No abstract available.


T-B cell interaction inhibits spontaneous apoptosis of mature lymphocytes in Bcl-2-deficient mice.

Nakayama K, Nakayama K, Dustin LB, Loh DY.

J Exp Med. 1995 Oct 1;182(4):1101-9.


Antigen-driven differentiation of naive Ig-transgenic B cells in vitro.

Dustin LB, Bullock ED, Hamada Y, Azuma T, Loh DY.

J Immunol. 1995 May 15;154(10):4936-49.


Pregnancy as a natural model of allograft tolerance. Interactions between adherent macrophages and trophoblast populations.

Lu CY, Redline RW, Shea CM, Dustin LB, McKay DB.

Transplantation. 1989 Nov;48(5):848-55.


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