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Items: 46

1.

Safety evaluation of a new anxiolytic product containing botanicals Souroubea spp. and Platanus spp. in dogs.

Masic A, Liu R, Simkus K, Wilson J, Baker J, Sanchez P, Saleem A, Harris CC, Durst T, Arnason JT.

Can J Vet Res. 2018 Jan;82(1):3-11.

PMID:
29382964
2.

New Botanical Anxiolytics for Use in Companion Animals and Humans.

Liu R, Ahmed F, Cayer C, Mullally M, Carballo AF, Rojas MO, Garcia M, Baker J, Masic A, Sanchez PE, Poveda L, Merali Z, Durst T, Arnason JT.

AAPS J. 2017 Nov;19(6):1626-1631. doi: 10.1208/s12248-017-0144-y. Epub 2017 Sep 11.

PMID:
28895076
3.

Anxiolytic activity and active principles of Piper amalago (Piperaceae), a medicinal plant used by the Q'eqchi' Maya to treat susto, a culture-bound illness.

Mullally M, Cayer C, Muhammad A, Walshe-Roussel B, Ahmed F, Sanchez-Vindas PE, Otarola Rojas M, Merali Z, Cal V, Durst T, Trudeau VL, Arnason JT.

J Ethnopharmacol. 2016 Jun 5;185:147-54. doi: 10.1016/j.jep.2016.03.013. Epub 2016 Mar 10.

PMID:
26972506
4.

Comparison of anorectic and emetic potencies of deoxynivalenol (vomitoxin) to the plant metabolite deoxynivalenol-3-glucoside and synthetic deoxynivalenol derivatives EN139528 and EN139544.

Wu W, Zhou HR, Bursian SJ, Pan X, Link JE, Berthiller F, Adam G, Krantis A, Durst T, Pestka JJ.

Toxicol Sci. 2014 Nov;142(1):167-81. doi: 10.1093/toxsci/kfu166. Epub 2014 Aug 30.

5.

Souroubea sympetala (Marcgraviaceae): a medicinal plant that exerts anxiolysis through interaction with the GABAA benzodiazepine receptor.

Mullally M, Cayer C, Kramp K, Otárola Rojas M, Sanchez Vindas P, Garcia M, Poveda Alvarez L, Durst T, Merali Z, Trudeau VL, Arnason JT.

Can J Physiol Pharmacol. 2014 Sep;92(9):758-64. doi: 10.1139/cjpp-2014-0213. Epub 2014 Jul 28.

PMID:
25140794
6.

Synthesis and receptor binding in trans-CD ring-fused A-CD estrogens: comparison with the cis-fused isomers.

Dabrota C, Asim M, Choueiri C, Gargaun A, Korobkov I, Butt A, Carlson KE, Katzenellenbogen JA, Wright JS, Durst T.

Bioorg Med Chem Lett. 2014 Aug 15;24(16):3841-4. doi: 10.1016/j.bmcl.2014.06.066. Epub 2014 Jun 27.

7.

Novel ligands balance estrogen receptor β and α agonism for safe and effective suppression of the vasomotor response in the ovariectomized female rat model of menopause.

McGregor C, Sau A, Ruddy SC, Leung D, Webb M, Durst T, Wright JS, Lagace D, Pratt MA.

Endocrinology. 2014 Jul;155(7):2480-91. doi: 10.1210/en.2013-1976. Epub 2014 May 13.

PMID:
24823389
8.

Effects of oral exposure to naturally-occurring and synthetic deoxynivalenol congeners on proinflammatory cytokine and chemokine mRNA expression in the mouse.

Wu W, He K, Zhou HR, Berthiller F, Adam G, Sugita-Konishi Y, Watanabe M, Krantis A, Durst T, Zhang H, Pestka JJ.

Toxicol Appl Pharmacol. 2014 Jul 15;278(2):107-15. doi: 10.1016/j.taap.2014.04.016. Epub 2014 Apr 29.

9.

Preferential estrogen receptor β ligands reduce Bcl-2 expression in hormone-resistant breast cancer cells to increase autophagy.

Ruddy SC, Lau R, Cabrita MA, McGregor C, McKay BC, Murphy LC, Wright JS, Durst T, Pratt MA.

Mol Cancer Ther. 2014 Jul;13(7):1882-93. doi: 10.1158/1535-7163.MCT-13-1066. Epub 2014 Apr 30.

10.

Dillapiol: a pyrethrum synergist for control of the Colorado potato beetle.

Liu SQ, Scott IM, Pelletier Y, Kramp K, Durst T, Sims SR, Arnason JT.

J Econ Entomol. 2014 Apr;107(2):797-805.

PMID:
24772563
11.

Ethnopharmacology of Souroubea sympetala and Souroubea gilgii (Marcgraviaceae) and identification of betulinic acid as an anxiolytic principle.

Puniani E, Cayer C, Kent P, Mullally M, Sánchez-Vindas P, Poveda Álvarez L, Cal V, Merali Z, Arnason JT, Durst T.

Phytochemistry. 2015 May;113:73-8. doi: 10.1016/j.phytochem.2014.02.017. Epub 2014 Mar 15.

PMID:
24641939
12.

Inhibition of bacterial quorum sensing and biofilm formation by extracts of neotropical rainforest plants.

Ta CA, Freundorfer M, Mah TF, Otárola-Rojas M, Garcia M, Sanchez-Vindas P, Poveda L, Maschek JA, Baker BJ, Adonizio AL, Downum K, Durst T, Arnason JT.

Planta Med. 2014 Mar;80(4):343-50. doi: 10.1055/s-0033-1360337. Epub 2014 Jan 31.

PMID:
24488718
13.

Distinct effects of IPSU and suvorexant on mouse sleep architecture.

Hoyer D, Dürst T, Fendt M, Jacobson LH, Betschart C, Hintermann S, Behnke D, Cotesta S, Laue G, Ofner S, Legangneux E, Gee CE.

Front Neurosci. 2013 Dec 10;7:235. doi: 10.3389/fnins.2013.00235. eCollection 2013.

14.

Experimental versus predicted affinities for ligand binding to estrogen receptor: iterative selection and rescoring of docked poses systematically improves the correlation.

Wright JS, Anderson JM, Shadnia H, Durst T, Katzenellenbogen JA.

J Comput Aided Mol Des. 2013 Aug;27(8):707-21. doi: 10.1007/s10822-013-9670-6. Epub 2013 Aug 24.

PMID:
23975271
15.

Phytochemical constituents of Sarracenia purpurea L. (pitcher plant).

Muhammad A, Haddad PS, Durst T, Arnason JT.

Phytochemistry. 2013 Oct;94:238-42. doi: 10.1016/j.phytochem.2013.05.015. Epub 2013 Jun 27.

PMID:
23810285
16.

Potent anti-inflammatory activity of sesquiterpene lactones from Neurolaena lobata (L.) R. Br. ex Cass., a Q'eqchi' Maya traditional medicine.

Walshe-Roussel B, Choueiri C, Saleem A, Asim M, Caal F, Cal V, Rojas MO, Pesek T, Durst T, Arnason JT.

Phytochemistry. 2013 Aug;92:122-7. doi: 10.1016/j.phytochem.2013.05.004. Epub 2013 Jun 5.

PMID:
23747054
17.

The dual orexin receptor antagonist almorexant induces sleep and decreases orexin-induced locomotion by blocking orexin 2 receptors.

Mang GM, Dürst T, Bürki H, Imobersteg S, Abramowski D, Schuepbach E, Hoyer D, Fendt M, Gee CE.

Sleep. 2012 Dec 1;35(12):1625-35. doi: 10.5665/sleep.2232.

18.

BC-spiro-estradiols. Synthesis and estrogen receptor binding affinity of four new estradiol isomers.

Asim M, Klonowska D, Choueiri C, Korobkov I, Carlson KE, Katzenellenbogen JA, Durst T.

Bioorg Med Chem Lett. 2012 Jun 1;22(11):3713-7. doi: 10.1016/j.bmcl.2012.04.022. Epub 2012 Apr 11.

PMID:
22546676
19.

Antibacterial properties of a glycolipid-rich extract and active principle from Nunavik collections of the macroalgae Fucus evanescens C. Agardh (Fucaceae).

Treyvaud Amiguet V, Jewell LE, Mao H, Sharma M, Hudson JB, Durst T, Allard M, Rochefort G, Arnason JT.

Can J Microbiol. 2011 Sep;57(9):745-9. doi: 10.1139/w11-065. Epub 2011 Aug 22.

PMID:
21859295
20.

A-CD estrogens. I. Substituent effects, hormone potency, and receptor subtype selectivity in a new family of flexible estrogenic compounds.

Wright JS, Shadnia H, Anderson JM, Durst T, Asim M, El-Salfiti M, Choueiri C, Pratt MA, Ruddy SC, Lau R, Carlson KE, Katzenellenbogen JA, O'Brien PJ, Wan L.

J Med Chem. 2011 Jan 27;54(2):433-48. doi: 10.1021/jm100513m. Epub 2010 Dec 29.

PMID:
21190382
21.

Bioassay-guided isolation of the antidiabetic principle from Sorbus decora (Rosaceae) used traditionally by the Eeyou Istchee Cree First Nations.

Guerrero-Analco JA, Martineau L, Saleem A, Madiraju P, Muhammad A, Durst T, Haddad P, Arnason JT.

J Nat Prod. 2010 Sep 24;73(9):1519-23. doi: 10.1021/np1003005.

PMID:
20738101
22.

Anxiolytic activity of a supercritical carbon dioxide extract of Souroubea sympetala (Marcgraviaceae).

Mullally M, Kramp K, Cayer C, Saleem A, Ahmed F, McRae C, Baker J, Goulah A, Otorola M, Sanchez P, Garcia M, Poveda L, Merali Z, Durst T, Trudeau VL, Arnason JT.

Phytother Res. 2011 Feb;25(2):264-70. doi: 10.1002/ptr.3246.

PMID:
20648677
23.

Triterpenoids from the bark of Ruptiliocarpon caracolito.

Asim M, Hussien H, Poveda L, Arnason JT, Durst T.

Phytochemistry. 2010 Aug;71(11-12):1418-22. doi: 10.1016/j.phytochem.2010.04.020. Epub 2010 May 23.

PMID:
20580789
24.

Structural constraints and the importance of lipophilicity for the mitochondrial uncoupling activity of naturally occurring caffeic acid esters with potential for the treatment of insulin resistance.

Eid HM, Vallerand D, Muhammad A, Durst T, Haddad PS, Martineau LC.

Biochem Pharmacol. 2010 Feb 1;79(3):444-54. doi: 10.1016/j.bcp.2009.08.026. Epub 2009 Sep 2.

PMID:
19732755
25.

Deconstructing estradiol: removal of B-ring generates compounds which are potent and subtype-selective estrogen receptor agonists.

Asim M, El-Salfiti M, Qian Y, Choueiri C, Salari S, Cheng J, Shadnia H, Bal M, Christine Pratt MA, Carlson KE, Katzenellenbogen JA, Wright JS, Durst T.

Bioorg Med Chem Lett. 2009 Feb 15;19(4):1250-3. doi: 10.1016/j.bmcl.2008.12.080. Epub 2008 Dec 24. Erratum in: Bioorg Med Chem Lett. 2009 May 1;19(9):2605. Asim, Mohammud [corrected to Asim, Muhammad]. Bioorg Med Chem Lett.2010 Nov 15;20(22):6861-2.

PMID:
19167882
26.

Bioassay-guided fractionation of lemon balm (Melissa officinalis L.) using an in vitro measure of GABA transaminase activity.

Awad R, Muhammad A, Durst T, Trudeau VL, Arnason JT.

Phytother Res. 2009 Aug;23(8):1075-81. doi: 10.1002/ptr.2712.

PMID:
19165747
27.

Antifungal and antioxidant activities of the phytomedicine pipsissewa, Chimaphila umbellata.

Galván IJ, Mir-Rashed N, Jessulat M, Atanya M, Golshani A, Durst T, Petit P, Amiguet VT, Boekhout T, Summerbell R, Cruz I, Arnason JT, Smith ML.

Phytochemistry. 2008 Feb;69(3):738-46. Epub 2007 Oct 22.

PMID:
17950387
28.

Spirocaracolitone triterpenoids from the bark of Ruptiliocarpon caracolito.

Asim M, Hussien H, Arnason JT, Poveda L, Durst T.

J Nat Prod. 2007 Aug;70(8):1228-32. Epub 2007 Aug 1.

PMID:
17665950
29.

Cytotoxicity and cytoprotective activity of naphthalenediols in rat cortical neurons.

Flueraru M, So R, Willmore WG, Poulter MO, Durst T, Charron M, Wright JS.

Chem Res Toxicol. 2006 Sep;19(9):1221-7.

PMID:
16978027
30.

Phytochemistry and antifungal properties of the newly discovered tree Pleodendron costaricense.

Treyvaud Amiguet V, Petit P, Ta CA, Nuñez R, Sánchez-Vindas P, Alvarez LP, Smith ML, Arnason JT, Durst T.

J Nat Prod. 2006 Jul;69(7):1005-9.

PMID:
16872133
31.

Cytotoxicity and cytoprotective activity in naphthalenediols depends on their tendency to form naphthoquinones.

Flueraru M, Chichirau A, Chepelev LL, Willmore WG, Durst T, Charron M, Barclay LR, Wright JS.

Free Radic Biol Med. 2005 Nov 15;39(10):1368-77. Epub 2005 Aug 19.

PMID:
16257646
32.

Analysis of Piperaceae germplasm by HPLC and LCMS: a method for isolating and identifying unsaturated amides from Piper spp extracts.

Scott IM, Puniani E, Jensen H, Livesey JF, Poveda L, Sanchez-Vindas P, Durst T, Arnason JT.

J Agric Food Chem. 2005 Mar 23;53(6):1907-13.

PMID:
15769112
33.

Mechanism of cytotoxicity of catechols and a naphthalenediol in PC12-AC cells: the connection between extracellular autoxidation and molecular electronic structure.

Chichirau A, Flueraru M, Chepelev LL, Wright JS, Willmore WG, Durst T, Hussain HH, Charron M.

Free Radic Biol Med. 2005 Feb 1;38(3):344-55.

PMID:
15629863
34.

Analysis of Fusarium graminearum mycotoxins in different biological matrices by LC/MS.

Bily AC, Reid LM, Savard ME, Reddy R, Blackwell BA, Campbell CM, Krantis A, Durst T, Philogène BJ, Arnason JT, Regnault-Roger C.

Mycopathologia. 2004 Jan;157(1):117-26.

PMID:
15008354
35.

Bioassay-guided isolation and identification of antifungal compounds from ginger.

Ficker C, Smith ML, Akpagana K, Gbeassor M, Zhang J, Durst T, Assabgui R, Arnason JT.

Phytother Res. 2003 Sep;17(8):897-902.

PMID:
13680820
36.

Development of novel antioxidants: design, synthesis, and reactivity.

Hussain HH, Babic G, Durst T, Wright JS, Flueraru M, Chichirau A, Chepelev LL.

J Org Chem. 2003 Sep 5;68(18):7023-32.

PMID:
12946144
37.

Traditionally-used antimalarials from the Meliaceae.

Omar S, Zhang J, MacKinnon S, Leaman D, Durst T, Philogene BJ, Arnason JT, Sanchez-Vindas PE, Poveda L, Tamez PA, Pezzuto JM.

Curr Top Med Chem. 2003;3(2):133-9. Review.

PMID:
12570769
38.

Asymmetric synthesis of the highly methylated tryptophan portion of the hemiasterlin tripeptides.

Reddy R, Jaquith JB, Neelagiri VR, Saleh-Hanna S, Durst T.

Org Lett. 2002 Mar 7;4(5):695-7.

PMID:
11869104
39.

Antimalarial activity of tropical Meliaceae extracts and gedunin derivatives.

MacKinnon S, Durst T, Arnason JT, Angerhofer C, Pezzuto J, Sanchez-Vindas PE, Poveda LJ, Gbeassor M.

J Nat Prod. 1997 Apr;60(4):336-41.

PMID:
9134742
40.

Methyl 4-hydroxy-3-(3'-methyl-2'-butenyl)benzoate, major insecticidal principle from Piper guanacastensis.

Pereda-Miranda R, Bernard CB, Durst T, Arnason JT, Sánchez-Vindas P, Poveda L, San Román L.

J Nat Prod. 1997 Mar;60(3):282-4.

PMID:
9090871
41.

Study of photoinduced energy and electron transfer in alpha-terthienyl-bovine serum albumin conjugates: a laser flash photolysis study.

Boch R, Mohtat N, Lear Y, Arnason JT, Durst T, Scaiano JC.

Photochem Photobiol. 1996 Jul;64(1):92-9.

PMID:
8787021
42.

Insecticidal neolignans from Piper decurrens.

Chauret DC, Bernard CB, Arnason JT, Durst T, Krishnamurty HG, Sanchez-Vindas P, Moreno N, Roman LS, Poveda L.

J Nat Prod. 1996 Feb;59(2):152-5.

PMID:
8991948
43.

Pharmacokinetics, metabolism and toxicity of the plant-derived photoxin alpha-terthienyl.

Marles R, Durst T, Kobaisy M, Soucy-Breau C, Abou-Zaid M, Arnason JT, Kacew S, Kanjanapothi D, Rujjanawate C, Meckes M, et al.

Pharmacol Toxicol. 1995 Sep;77(3):164-8.

PMID:
8884878
44.

Insecticidal defenses of Piperaceae from the neotropics.

Bernard CB, Krishanmurty HG, Chauret D, Durst T, Philogène BJ, Sánchez-Vindas P, Hasbun C, Poveda L, San Román L, Arnason JT.

J Chem Ecol. 1995 Jun;21(6):801-14. doi: 10.1007/BF02033462.

PMID:
24234319
45.

Limited nonenzymatic glucosylation of low-density lipoprotein does not alter its catabolism in tissue culture.

Schleicher E, Olgemöller B, Schön J, Dürst T, Wieland OH.

Biochim Biophys Acta. 1985 Aug 30;846(2):226-33.

PMID:
3927987
46.

Epileptic phenomena induced in the cat by the antidepressants maprotiline, imipramine, clomipramine, and amitriptyline.

Koella WP, Glatt A, Klebs K, Dürst T.

Biol Psychiatry. 1979 Jun;14(3):485-97.

PMID:
476233

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