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Items: 11


Clonal Evolution and Changes in Two AML Patients Detected with A Novel Single-Cell DNA Sequencing Platform.

Xu L, Durruthy-Durruthy R, Eastburn DJ, Pellegrino M, Shah O, Meyer E, Zehnder J.

Sci Rep. 2019 Jul 31;9(1):11119. doi: 10.1038/s41598-019-47297-z.


Clonal Selection with RAS Pathway Activation Mediates Secondary Clinical Resistance to Selective FLT3 Inhibition in Acute Myeloid Leukemia.

McMahon CM, Ferng T, Canaani J, Wang ES, Morrissette JJD, Eastburn DJ, Pellegrino M, Durruthy-Durruthy R, Watt CD, Asthana S, Lasater EA, DeFilippis R, Peretz CAC, McGary LHF, Deihimi S, Logan AC, Luger SM, Shah NP, Carroll M, Smith CC, Perl AE.

Cancer Discov. 2019 Aug;9(8):1050-1063. doi: 10.1158/2159-8290.CD-18-1453. Epub 2019 May 14.


Single Cell Transcriptomics Reveal Abnormalities in Neurosensory Patterning of the Chd7 Mutant Mouse Ear.

Durruthy-Durruthy R, Sperry ED, Bowen ME, Attardi LD, Heller S, Martin DM.

Front Genet. 2018 Oct 23;9:473. doi: 10.3389/fgene.2018.00473. eCollection 2018.


High-throughput single-cell DNA sequencing of acute myeloid leukemia tumors with droplet microfluidics.

Pellegrino M, Sciambi A, Treusch S, Durruthy-Durruthy R, Gokhale K, Jacob J, Chen TX, Geis JA, Oldham W, Matthews J, Kantarjian H, Futreal PA, Patel K, Jones KW, Takahashi K, Eastburn DJ.

Genome Res. 2018 Sep;28(9):1345-1352. doi: 10.1101/gr.232272.117. Epub 2018 Aug 7.


Using Fluidigm C1 to Generate Single-Cell Full-Length cDNA Libraries for mRNA Sequencing.

Durruthy-Durruthy R, Ray M.

Methods Mol Biol. 2018;1706:199-221. doi: 10.1007/978-1-4939-7471-9_11. Review.


Quantitative High-Resolution Cellular Map of the Organ of Corti.

Waldhaus J, Durruthy-Durruthy R, Heller S.

Cell Rep. 2015 Jun 9;11(9):1385-99. doi: 10.1016/j.celrep.2015.04.062. Epub 2015 May 28.


Identification and characterization of mouse otic sensory lineage genes.

Hartman BH, Durruthy-Durruthy R, Laske RD, Losorelli S, Heller S.

Front Cell Neurosci. 2015 Mar 19;9:79. doi: 10.3389/fncel.2015.00079. eCollection 2015.


3D computational reconstruction of tissues with hollow spherical morphologies using single-cell gene expression data.

Durruthy-Durruthy R, Gottlieb A, Heller S.

Nat Protoc. 2015 Mar;10(3):459-474. doi: 10.1038/nprot.2015.022. Epub 2015 Feb 12.


Applications for single cell trajectory analysis in inner ear development and regeneration.

Durruthy-Durruthy R, Heller S.

Cell Tissue Res. 2015 Jul;361(1):49-57. doi: 10.1007/s00441-014-2079-2. Epub 2014 Dec 24. Review.


Reconstruction of the mouse otocyst and early neuroblast lineage at single-cell resolution.

Durruthy-Durruthy R, Gottlieb A, Hartman BH, Waldhaus J, Laske RD, Altman R, Heller S.

Cell. 2014 May 8;157(4):964-78. doi: 10.1016/j.cell.2014.03.036. Epub 2014 Apr 24.


Inner ear hair cell-like cells from human embryonic stem cells.

Ronaghi M, Nasr M, Ealy M, Durruthy-Durruthy R, Waldhaus J, Diaz GH, Joubert LM, Oshima K, Heller S.

Stem Cells Dev. 2014 Jun 1;23(11):1275-84. doi: 10.1089/scd.2014.0033. Epub 2014 Mar 10.

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