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Items: 1 to 50 of 55

1.

An activating mutation of the NSD2 histone methyltransferase drives oncogenic reprogramming in acute lymphocytic leukemia.

Swaroop A, Oyer JA, Will CM, Huang X, Yu W, Troche C, Bulic M, Durham BH, Wen QJ, Crispino JD, MacKerell AD Jr, Bennett RL, Kelleher NL, Licht JD.

Oncogene. 2019 Jan;38(5):671-686. doi: 10.1038/s41388-018-0474-y. Epub 2018 Aug 31.

PMID:
30171259
2.

Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations.

Lee SC, North K, Kim E, Jang E, Obeng E, Lu SX, Liu B, Inoue D, Yoshimi A, Ki M, Yeo M, Zhang XJ, Kim MK, Cho H, Chung YR, Taylor J, Durham BH, Kim YJ, Pastore A, Monette S, Palacino J, Seiler M, Buonamici S, Smith PG, Ebert BL, Bradley RK, Abdel-Wahab O.

Cancer Cell. 2018 Aug 13;34(2):225-241.e8. doi: 10.1016/j.ccell.2018.07.003.

PMID:
30107174
3.

Genetic and epigenetic evolution as a contributor to WT1-mutant leukemogenesis.

Pronier E, Bowman RL, Ahn J, Glass J, Kandoth C, Merlinsky TR, Whitfield JT, Durham BH, Gruet A, Hanasoge Somasundara AV, Rampal R, Melnick A, Koche RP, Taylor BS, Levine RL.

Blood. 2018 Sep 20;132(12):1265-1278. doi: 10.1182/blood-2018-03-837468. Epub 2018 Jul 31.

4.

Oncogenic TRK fusions are amenable to inhibition in hematologic malignancies.

Taylor J, Pavlick D, Yoshimi A, Marcelus C, Chung SS, Hechtman JF, Benayed R, Cocco E, Durham BH, Bitner L, Inoue D, Chung YR, Mullaney K, Watts JM, Diamond EL, Albacker LA, Mughal TI, Ebata K, Tuch BB, Ku N, Scaltriti M, Roshal M, Arcila M, Ali S, Hyman DM, Park JH, Abdel-Wahab O.

J Clin Invest. 2018 Aug 31;128(9):3819-3825. doi: 10.1172/JCI120787. Epub 2018 Aug 6.

5.

Consensus recommendations for the diagnosis and clinical management of Rosai-Dorfman-Destombes disease.

Abla O, Jacobsen E, Picarsic J, Krenova Z, Jaffe R, Emile JF, Durham BH, Braier J, Charlotte F, Donadieu J, Cohen-Aubart F, Rodriguez-Galindo C, Allen C, Whitlock JA, Weitzman S, McClain KL, Haroche J, Diamond EL.

Blood. 2018 Jun 28;131(26):2877-2890. doi: 10.1182/blood-2018-03-839753. Epub 2018 May 2. Review.

PMID:
29720485
6.

Molecular characterization of the histiocytoses: Neoplasia of dendritic cells and macrophages.

Durham BH.

Semin Cell Dev Biol. 2019 Feb;86:62-76. doi: 10.1016/j.semcdb.2018.03.002. Epub 2018 Mar 16. Review.

PMID:
29526544
7.

Single-agent dabrafenib for BRAFV600E-mutated histiocytosis.

Bhatia A, Ulaner G, Rampal R, Hyman DM, Abdel-Wahab O, Durham BH, Dogan A, Ozkaya N, Lacouture ME, Hajdenberg J, Ganzel C, Diamond EL.

Haematologica. 2018 Apr;103(4):e177-e180. doi: 10.3324/haematol.2017.185298. Epub 2018 Feb 22. No abstract available.

8.

The histopathology of Erdheim-Chester disease: a comprehensive review of a molecularly characterized cohort.

Ozkaya N, Rosenblum MK, Durham BH, Pichardo JD, Abdel-Wahab O, Hameed MR, Busam KJ, Travis WD, Diamond EL, Dogan A.

Mod Pathol. 2018 Apr;31(4):581-597. doi: 10.1038/modpathol.2017.160. Epub 2017 Dec 1.

PMID:
29192649
9.

A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease.

Mass E, Jacome-Galarza CE, Blank T, Lazarov T, Durham BH, Ozkaya N, Pastore A, Schwabenland M, Chung YR, Rosenblum MK, Prinz M, Abdel-Wahab O, Geissmann F.

Nature. 2017 Sep 21;549(7672):389-393. doi: 10.1038/nature23672. Epub 2017 Aug 30.

10.

Genomic analysis of hairy cell leukemia identifies novel recurrent genetic alterations.

Durham BH, Getta B, Dietrich S, Taylor J, Won H, Bogenberger JM, Scott S, Kim E, Chung YR, Chung SS, Hüllein J, Walther T, Wang L, Lu SX, Oakes CC, Tibes R, Haferlach T, Taylor BS, Tallman MS, Berger MF, Park JH, Zenz T, Abdel-Wahab O.

Blood. 2017 Oct 5;130(14):1644-1648. doi: 10.1182/blood-2017-01-765107. Epub 2017 Aug 11.

11.

Novel activating BRAF fusion identifies a recurrent alternative mechanism for ERK activation in pediatric Langerhans cell histiocytosis.

Zarnegar S, Durham BH, Khattar P, Shukla NN, Benayed R, Lacouture ME, Lavi E, Lyden DC, Diamond EL, Dunkel IJ, Abdel-Wahab O.

Pediatr Blood Cancer. 2018 Jan;65(1). doi: 10.1002/pbc.26699. Epub 2017 Jul 27.

12.

miR-99 regulates normal and malignant hematopoietic stem cell self-renewal.

Khalaj M, Woolthuis CM, Hu W, Durham BH, Chu SH, Qamar S, Armstrong SA, Park CY.

J Exp Med. 2017 Jul 21. pii: jem.20161595. doi: 10.1084/jem.20161595. [Epub ahead of print]

13.

High prevalence of myeloid neoplasms in adults with non-Langerhans cell histiocytosis.

Papo M, Diamond EL, Cohen-Aubart F, Emile JF, Roos-Weil D, Gupta N, Durham BH, Ozkaya N, Dogan A, Ulaner GA, Rampal R, Kahn JE, Sené T, Charlotte F, Hervier B, Besnard C, Bernard OA, Settegrana C, Droin N, Hélias-Rodzewicz Z, Amoura Z, Abdel-Wahab O, Haroche J.

Blood. 2017 Aug 24;130(8):1007-1013. doi: 10.1182/blood-2017-01-761718. Epub 2017 Jul 5.

14.

Robust patient-derived xenografts of MDS/MPN overlap syndromes capture the unique characteristics of CMML and JMML.

Yoshimi A, Balasis ME, Vedder A, Feldman K, Ma Y, Zhang H, Lee SC, Letson C, Niyongere S, Lu SX, Ball M, Taylor J, Zhang Q, Zhao Y, Youssef S, Chung YR, Zhang XJ, Durham BH, Yang W, List AF, Loh ML, Klimek V, Berger MF, Stieglitz E, Padron E, Abdel-Wahab O.

Blood. 2017 Jul 27;130(4):397-407. doi: 10.1182/blood-2017-01-763219. Epub 2017 Jun 2. Erratum in: Blood. 2017 Sep 28;130(13):1602.

15.

Functional evidence for derivation of systemic histiocytic neoplasms from hematopoietic stem/progenitor cells.

Durham BH, Roos-Weil D, Baillou C, Cohen-Aubart F, Yoshimi A, Miyara M, Papo M, Hélias-Rodzewicz Z, Terrones N, Ozkaya N, Dogan A, Rampal R, Urbain F, Le Fèvre L, Diamond EL, Park CY, Papo T, Charlotte F, Gorochov G, Taly V, Bernard OA, Amoura Z, Abdel-Wahab O, Lemoine FM, Haroche J, Emile JF.

Blood. 2017 Jul 13;130(2):176-180. doi: 10.1182/blood-2016-12-757377. Epub 2017 May 31.

16.

ASXL2 is essential for haematopoiesis and acts as a haploinsufficient tumour suppressor in leukemia.

Micol JB, Pastore A, Inoue D, Duployez N, Kim E, Lee SC, Durham BH, Chung YR, Cho H, Zhang XJ, Yoshimi A, Krivtsov A, Koche R, Solary E, Sinha A, Preudhomme C, Abdel-Wahab O.

Nat Commun. 2017 May 18;8:15429. doi: 10.1038/ncomms15429.

17.

Hematopoietic origin of Langerhans cell histiocytosis and Erdheim-Chester disease in adults.

Milne P, Bigley V, Bacon CM, Néel A, McGovern N, Bomken S, Haniffa M, Diamond EL, Durham BH, Visser J, Hunt D, Gunawardena H, Macheta M, McClain KL, Allen C, Abdel-Wahab O, Collin M.

Blood. 2017 Jul 13;130(2):167-175. doi: 10.1182/blood-2016-12-757823. Epub 2017 May 16.

18.

DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling.

Guryanova OA, Shank K, Spitzer B, Luciani L, Koche RP, Garrett-Bakelman FE, Ganzel C, Durham BH, Mohanty A, Hoermann G, Rivera SA, Chramiec AG, Pronier E, Bastian L, Keller MD, Tovbin D, Loizou E, Weinstein AR, Gonzalez AR, Lieu YK, Rowe JM, Pastore F, McKenney AS, Krivtsov AV, Sperr WR, Cross JR, Mason CE, Tallman MS, Arcila ME, Abdel-Wahab O, Armstrong SA, Kubicek S, Staber PB, Gönen M, Paietta EM, Melnick AM, Nimer SD, Mukherjee S, Levine RL.

Nat Med. 2016 Dec;22(12):1488-1495. doi: 10.1038/nm.4210. Epub 2016 Nov 14.

19.

Anakinra as efficacious therapy for 2 cases of intracranial Erdheim-Chester disease.

Diamond EL, Abdel-Wahab O, Durham BH, Dogan A, Ozkaya N, Brody L, Arcila M, Bowers C, Fluchel M.

Blood. 2016 Oct 6;128(14):1896-1898. doi: 10.1182/blood-2016-06-725143. Epub 2016 Aug 17. No abstract available.

20.

Erratum: Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins.

Lee SC, Dvinge H, Kim E, Cho H, Micol JB, Chung YR, Durham BH, Yoshimi A, Kim YJ, Thomas M, Lobry C, Chen CW, Pastore A, Taylor J, Wang X, Krivtsov A, Armstrong SA, Palacino J, Buonamici S, Smith PG, Bradley RK, Abdel-Wahab O.

Nat Med. 2016 Jun 7;22(6):692. doi: 10.1038/nm0616-692d. No abstract available.

21.

Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins.

Lee SC, Dvinge H, Kim E, Cho H, Micol JB, Chung YR, Durham BH, Yoshimi A, Kim YJ, Thomas M, Lobry C, Chen CW, Pastore A, Taylor J, Wang X, Krivtsov A, Armstrong SA, Palacino J, Buonamici S, Smith PG, Bradley RK, Abdel-Wahab O.

Nat Med. 2016 Jun;22(6):672-8. doi: 10.1038/nm.4097. Epub 2016 May 2. Erratum in: Nat Med. 2016 Jun 7;22(6):692.

22.

Histiocytic neoplasms in the era of personalized genomic medicine.

Durham BH, Diamond EL, Abdel-Wahab O.

Curr Opin Hematol. 2016 Jul;23(4):416-25. doi: 10.1097/MOH.0000000000000256. Review.

23.

MSI2 is required for maintaining activated myelodysplastic syndrome stem cells.

Taggart J, Ho TC, Amin E, Xu H, Barlowe TS, Perez AR, Durham BH, Tivnan P, Okabe R, Chow A, Vu L, Park SM, Prieto C, Famulare C, Patel M, Lengner CJ, Verma A, Roboz G, Guzman M, Klimek VM, Abdel-Wahab O, Leslie C, Nimer SD, Kharas MG.

Nat Commun. 2016 Feb 22;7:10739. doi: 10.1038/ncomms10739.

24.

Dnmt3a regulates myeloproliferation and liver-specific expansion of hematopoietic stem and progenitor cells.

Guryanova OA, Lieu YK, Garrett-Bakelman FE, Spitzer B, Glass JL, Shank K, Martinez AB, Rivera SA, Durham BH, Rapaport F, Keller MD, Pandey S, Bastian L, Tovbin D, Weinstein AR, Teruya-Feldstein J, Abdel-Wahab O, Santini V, Mason CE, Melnick AM, Mukherjee S, Levine RL.

Leukemia. 2016 May;30(5):1133-42. doi: 10.1038/leu.2015.358. Epub 2015 Dec 29.

25.

Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms.

Diamond EL, Durham BH, Haroche J, Yao Z, Ma J, Parikh SA, Wang Z, Choi J, Kim E, Cohen-Aubart F, Lee SC, Gao Y, Micol JB, Campbell P, Walsh MP, Sylvester B, Dolgalev I, Aminova O, Heguy A, Zappile P, Nakitandwe J, Ganzel C, Dalton JD, Ellison DW, Estrada-Veras J, Lacouture M, Gahl WA, Stephens PJ, Miller VA, Ross JS, Ali SM, Briggs SR, Fasan O, Block J, Héritier S, Donadieu J, Solit DB, Hyman DM, Baselga J, Janku F, Taylor BS, Park CY, Amoura Z, Dogan A, Emile JF, Rosen N, Gruber TA, Abdel-Wahab O.

Cancer Discov. 2016 Feb;6(2):154-65. doi: 10.1158/2159-8290.CD-15-0913. Epub 2015 Nov 13.

26.

Sonographic appearance of a dermoid cyst (mature cystic teratoma) of the spleen.

Gerscovich EO, Fananapazir G, McGahan JP, Hirschbein JS, Naderi S, Corwin MT, Durham BH.

J Clin Ultrasound. 2015 Feb;43(2):132-4. doi: 10.1002/jcu.22203. Epub 2014 Jul 17.

PMID:
25044283
27.

Mantle cell lymphoma and involvement of the orbit and ocular adnexa.

Vali Khojeini E, Durham BH, Chen M.

Case Rep Pathol. 2013;2013:581856. doi: 10.1155/2013/581856. Epub 2013 Apr 4.

28.

Plasma obestatin and autonomic function are altered in orexin-deficient narcolepsy, but ghrelin is unchanged.

Huda MS, Mani H, Durham BH, Dovey TM, Halford JC, Aditya BS, Pinkney JH, Wilding JP, Hart IK.

Endocrine. 2013 Jun;43(3):696-704. doi: 10.1007/s12020-012-9838-1. Epub 2012 Nov 23.

PMID:
23179778
29.

Rapidly progressive primary leptomeningeal atypical teratoid/rhabdoid tumor: a report of 2 cases.

Gauvain KM, Durham BH, McHugh M, Geller TJ.

J Child Neurol. 2012 Dec;27(12):1597-601. doi: 10.1177/0883073812436878. Epub 2012 Feb 28.

PMID:
22378667
30.

Resistant Fusarium keratitis progressing to endophthalmitis.

Edelstein SL, Akduman L, Durham BH, Fothergill AW, Hsu HY.

Eye Contact Lens. 2012 Sep;38(5):331-5. doi: 10.1097/ICL.0b013e318235c5af. Review.

PMID:
21993589
31.

Effect of oral phosphate and alendronate on bone mineral density when given as adjunctive therapy to growth hormone replacement in adult growth hormone deficiency.

White HD, Ahmad AM, Durham BH, Joshi AA, Fraser WD, Vora JP.

J Clin Endocrinol Metab. 2011 Mar;96(3):726-36. doi: 10.1210/jc.2010-1929. Epub 2011 Jan 20.

PMID:
21252245
32.

Correlation of serum-adjusted calcium with ionized calcium over a 24-h period in patients with adult growth hormone deficiency before and after growth hormone replacement.

White HD, Joshi AA, Ahmad AM, Durham BH, Vora JP, Fraser WD.

Ann Clin Biochem. 2010 May;47(Pt 3):212-6. doi: 10.1258/acb.2010.009178. Epub 2010 Apr 14.

PMID:
20392749
33.

The circulating concentration and ratio of total and high molecular weight adiponectin in post-menopausal women with and without osteoporosis and its association with body mass index and biochemical markers of bone metabolism.

Sodi R, Hazell MJ, Durham BH, Rees C, Ranganath LR, Fraser WD.

Clin Biochem. 2009 Sep;42(13-14):1375-80. doi: 10.1016/j.clinbiochem.2009.06.003. Epub 2009 Jun 10.

PMID:
19523465
34.

Effects of peripheral administration of synthetic human glucose-dependent insulinotropic peptide (GIP) on energy expenditure and subjective appetite sensations in healthy normal weight subjects and obese patients with type 2 diabetes.

Daousi C, Wilding JP, Aditya S, Durham BH, Cleator J, Pinkney JH, Ranganath LR.

Clin Endocrinol (Oxf). 2009 Aug;71(2):195-201. doi: 10.1111/j.1365-2265.2008.03451.x. Epub 2008 Oct 20.

PMID:
19178509
35.

Effects of growth hormone administration on bone mineral metabolism, PTH sensitivity and PTH secretory rhythm in postmenopausal women with established osteoporosis.

Joseph F, Ahmad AM, Ul-Haq M, Durham BH, Whittingham P, Fraser WD, Vora JP.

J Bone Miner Res. 2008 May;23(5):721-9.

36.

The association of circulating ferritin with serum concentrations of fibroblast growth factor-23 measured by three commercial assays.

Durham BH, Joseph F, Bailey LM, Fraser WD.

Ann Clin Biochem. 2007 Sep;44(Pt 5):463-6.

PMID:
17761032
37.

Plasma obestatin levels are lower in obese and post-gastrectomy subjects, but do not change in response to a meal.

Huda MS, Durham BH, Wong SP, Deepak D, Kerrigan D, McCulloch P, Ranganath L, Pinkney J, Wilding JP.

Int J Obes (Lond). 2008 Jan;32(1):129-35. Epub 2007 Jul 31.

PMID:
17667911
38.

PTH circadian rhythm and PTH target-organ sensitivity is altered in patients with adult growth hormone deficiency with low BMD.

White HD, Ahmad AM, Durham BH, Peter R, Prabhakar VK, Corlett P, Vora JP, Fraser WD.

J Bone Miner Res. 2007 Nov;22(11):1798-807.

39.

Lack of an acute effect of ghrelin on markers of bone turnover in healthy controls and post-gastrectomy subjects.

Huda MS, Durham BH, Wong SP, Dovey TM, McCulloch P, Kerrigan D, Pinkney JH, Fraser WD, Wilding JP.

Bone. 2007 Sep;41(3):406-13. Epub 2007 May 31.

PMID:
17613297
40.

The circadian rhythm of osteoprotegerin and its association with parathyroid hormone secretion.

Joseph F, Chan BY, Durham BH, Ahmad AM, Vinjamuri S, Gallagher JA, Vora JP, Fraser WD.

J Clin Endocrinol Metab. 2007 Aug;92(8):3230-8. Epub 2007 Jun 5.

PMID:
17550963
41.

Effect of active acromegaly and its treatment on parathyroid circadian rhythmicity and parathyroid target-organ sensitivity.

White HD, Ahmad AM, Durham BH, Chandran S, Patwala A, Fraser WD, Vora JP.

J Clin Endocrinol Metab. 2006 Mar;91(3):913-9. Epub 2005 Dec 13.

PMID:
16352693
42.

Growth hormone replacement is important for the restoration of parathyroid hormone sensitivity and improvement in bone metabolism in older adult growth hormone-deficient patients.

White HD, Ahmad AM, Durham BH, Patwala A, Whittingham P, Fraser WD, Vora JP.

J Clin Endocrinol Metab. 2005 Jun;90(6):3371-80. Epub 2005 Mar 1.

PMID:
15741264
43.

Parathyroid responsiveness to hypocalcemic and hypercalcemic stimuli in adult growth hormone deficiency after growth hormone replacement.

Ahmad AM, Hopkins MT, Thomas J, Durham BH, Fraser WD, Vora JP.

Am J Physiol Endocrinol Metab. 2004 Jun;286(6):E986-93.

44.

Effect of anticoagulants and storage temperature on the stability of receptor activator for nuclear factor-kappa B ligand and osteoprotegerin in plasma and serum.

Chan BY, Buckley KA, Durham BH, Gallagher JA, Fraser WD.

Clin Chem. 2003 Dec;49(12):2083-5. No abstract available.

45.

Effects of growth hormone replacement on parathyroid hormone sensitivity and bone mineral metabolism.

Ahmad AM, Thomas J, Clewes A, Hopkins MT, Guzder R, Ibrahim H, Durham BH, Vora JP, Fraser WD.

J Clin Endocrinol Metab. 2003 Jun;88(6):2860-8.

PMID:
12788900
46.

Parathyroid hormone secretory pattern, circulating activity, and effect on bone turnover in adult growth hormone deficiency.

Ahmad AM, Hopkins MT, Fraser WD, Ooi CG, Durham BH, Vora JP.

Bone. 2003 Feb;32(2):170-9.

PMID:
12633789
47.

Biochemical markers of bone turnover following high-dose chemotherapy and autografting in multiple myeloma.

Clark RE, Flory AJ, Ion EM, Woodcock BE, Durham BH, Fraser WD.

Blood. 2000 Oct 15;96(8):2697-702.

48.
49.
50.

Differences in the stability of intact osteocalcin in serum, lithium heparin plasma and EDTA plasma.

Durham BH, Robinson J, Fraser WD.

Ann Clin Biochem. 1995 Jul;32 ( Pt 4):422-3. No abstract available.

PMID:
7486805

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