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Items: 21


The Estrogen-Induced miR-19 Downregulates Secretory Leucoprotease Inhibitor Expression in Monocytes.

McKiernan PJ, Smith SGJ, Durham AL, Adcock IM, McElvaney NG, Greene CM.

J Innate Immun. 2019 Jul 2:1-13. doi: 10.1159/000500419. [Epub ahead of print]


Bromodomain and Extraterminal (BET) Protein Inhibition Restores Redox Balance and Inhibits Myofibroblast Activation.

Stock CJW, Michaeloudes C, Leoni P, Durham AL, Mumby S, Wells AU, Chung KF, Adcock IM, Renzoni EA, Lindahl GE.

Biomed Res Int. 2019 Apr 18;2019:1484736. doi: 10.1155/2019/1484736. eCollection 2019.


Low-frequency ventilation during cardiopulmonary bypass for lung protection: A randomized controlled trial.

Fiorentino F, Jaaly EA, Durham AL, Adcock IM, Lockwood G, Rogers C, Ascione R, Reeves BC, Angelini GD.

J Card Surg. 2019 Jun;34(6):385-399. doi: 10.1111/jocs.14044. Epub 2019 May 2.


Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness.

Durham AL, Speer MY, Scatena M, Giachelli CM, Shanahan CM.

Cardiovasc Res. 2018 Mar 15;114(4):590-600. doi: 10.1093/cvr/cvy010.


Sputum transcriptomics reveal upregulation of IL-1 receptor family members in patients with severe asthma.

Rossios C, Pavlidis S, Hoda U, Kuo CH, Wiegman C, Russell K, Sun K, Loza MJ, Baribaud F, Durham AL, Ojo O, Lutter R, Rowe A, Bansal A, Auffray C, Sousa A, Corfield J, Djukanovic R, Guo Y, Sterk PJ, Chung KF, Adcock IM; Unbiased Biomarkers for the Prediction of Respiratory Diseases Outcomes (U-BIOPRED) Consortia Project Team.

J Allergy Clin Immunol. 2018 Feb;141(2):560-570. doi: 10.1016/j.jaci.2017.02.045. Epub 2017 May 18.


BET proteins are a key component of immunoglobulin gene expression.

Shim JM, Lee JS, Russell KE, Wiegman CH, Barnes PJ, Fear D, Adcock IM, Durham AL.

Epigenomics. 2017 Apr;9(4):393-406. doi: 10.2217/epi-2016-0147. Epub 2017 Mar 21.


COPD immunopathology.

Caramori G, Casolari P, Barczyk A, Durham AL, Di Stefano A, Adcock I.

Semin Immunopathol. 2016 Jul;38(4):497-515. doi: 10.1007/s00281-016-0561-5. Epub 2016 May 13. Review.


Corticosteroid modulation of immunoglobulin expression and B-cell function in COPD.

Lee J, Machin M, Russell KE, Pavlidis S, Zhu J, Barnes PJ, Chung KF, Adcock IM, Durham AL.

FASEB J. 2016 May;30(5):2014-26. doi: 10.1096/fj.201500135. Epub 2016 Feb 17.


The MIF Antagonist ISO-1 Attenuates Corticosteroid-Insensitive Inflammation and Airways Hyperresponsiveness in an Ozone-Induced Model of COPD.

Russell KE, Chung KF, Clarke CJ, Durham AL, Mallia P, Footitt J, Johnston SL, Barnes PJ, Hall SR, Simpson KD, Starkey MR, Hansbro PM, Adcock IM, Wiegman CH.

PLoS One. 2016 Jan 11;11(1):e0146102. doi: 10.1371/journal.pone.0146102. eCollection 2016.


Epigenome-modifying tools in asthma.

Brook PO, Perry MM, Adcock IM, Durham AL.

Epigenomics. 2015;7(6):1017-32. doi: 10.2217/epi.15.53. Epub 2015 Oct 7. Review.


The relationship between COPD and lung cancer.

Durham AL, Adcock IM.

Lung Cancer. 2015 Nov;90(2):121-7. doi: 10.1016/j.lungcan.2015.08.017. Epub 2015 Aug 29. Review.


Targeted anti-inflammatory therapeutics in asthma and chronic obstructive lung disease.

Durham AL, Caramori G, Chung KF, Adcock IM.

Transl Res. 2016 Jan;167(1):192-203. doi: 10.1016/j.trsl.2015.08.004. Epub 2015 Aug 20. Review.


Glycogen synthase kinase-3β modulation of glucocorticoid responsiveness in COPD.

Ngkelo A, Hoffmann RF, Durham AL, Marwick JA, Brandenburg SM, de Bruin HG, Jonker MR, Rossios C, Tsitsiou E, Caramori G, Contoli M, Casolari P, Monaco F, Andò F, Speciale G, Kilty I, Chung KF, Papi A, Lindsay MA, Ten Hacken NH, van den Berge M, Timens W, Barnes PJ, van Oosterhout AJ, Adcock IM, Kirkham PA, Heijink IH.

Am J Physiol Lung Cell Mol Physiol. 2015 Nov 15;309(10):L1112-23. doi: 10.1152/ajplung.00077.2015. Epub 2015 Aug 28.


Oxidative and Nitrosative Stress and Histone Deacetylase-2 Activity in Exacerbations of COPD.

Footitt J, Mallia P, Durham AL, Ho WE, Trujillo-Torralbo MB, Telcian AG, Del Rosario A, Chang C, Peh HY, Kebadze T, Aniscenko J, Stanciu L, Essilfie-Quaye S, Ito K, Barnes PJ, Elkin SL, Kon OM, Wong WS, Adcock IM, Johnston SL.

Chest. 2016 Jan;149(1):62-73. doi: 10.1378/chest.14-2637. Epub 2016 Jan 6.


BET bromodomains regulate transforming growth factor-β-induced proliferation and cytokine release in asthmatic airway smooth muscle.

Perry MM, Durham AL, Austin PJ, Adcock IM, Chung KF.

J Biol Chem. 2015 Apr 3;290(14):9111-21. doi: 10.1074/jbc.M114.612671. Epub 2015 Feb 19.


Innate immunity but not NLRP3 inflammasome activation correlates with severity of stable COPD.

Di Stefano A, Caramori G, Barczyk A, Vicari C, Brun P, Zanini A, Cappello F, Garofano E, Padovani A, Contoli M, Casolari P, Durham AL, Chung KF, Barnes PJ, Papi A, Adcock I, Balbi B.

Thorax. 2014 Jun;69(6):516-24. doi: 10.1136/thoraxjnl-2012-203062. Epub 2014 Jan 15.


Regulation of Wnt4 in chronic obstructive pulmonary disease.

Durham AL, McLaren A, Hayes BP, Caramori G, Clayton CL, Barnes PJ, Chung KF, Adcock IM.

FASEB J. 2013 Jun;27(6):2367-81. doi: 10.1096/fj.12-217083. Epub 2013 Mar 5.


Coordinated regulation of IL-4 and IL-13 expression in human T cells: 3C analysis for DNA looping.

Yao X, Zha W, Song W, He H, Huang M, Jazrawi E, Lavender P, Barnes PJ, Adcock IM, Durham AL.

Biochem Biophys Res Commun. 2012 Jan 20;417(3):996-1001. doi: 10.1016/j.bbrc.2011.12.069. Epub 2011 Dec 27.


Epigenetics of asthma.

Durham AL, Wiegman C, Adcock IM.

Biochim Biophys Acta. 2011 Nov;1810(11):1103-9. doi: 10.1016/j.bbagen.2011.03.006. Epub 2011 Mar 21. Review.


Treatment effects of low-dose theophylline combined with an inhaled corticosteroid in COPD.

Ford PA, Durham AL, Russell RE, Gordon F, Adcock IM, Barnes PJ.

Chest. 2010 Jun;137(6):1338-44. doi: 10.1378/chest.09-2363. Epub 2010 Mar 18.


New plasmid tools for genetic analysis of Actinobacillus pleuropneumoniae and other pasteurellaceae.

Bossé JT, Durham AL, Rycroft AN, Kroll JS, Langford PR.

Appl Environ Microbiol. 2009 Oct;75(19):6124-31. doi: 10.1128/AEM.00809-09. Epub 2009 Aug 7.

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