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Items: 1 to 50 of 124

1.

Fetal hemoglobin does not inhibit Plasmodium falciparum growth.

Archer NM, Petersen N, Duraisingh MT.

Blood Adv. 2019 Jul 23;3(14):2149-2152. doi: 10.1182/bloodadvances.2019000399. No abstract available.

2.

Generation of an immortalized erythroid progenitor cell line from peripheral blood: A model system for the functional analysis of Plasmodium spp. invasion.

Scully EJ, Shabani E, Rangel GW, Grüring C, Kanjee U, Clark MA, Chaand M, Kurita R, Nakamura Y, Ferreira MU, Duraisingh MT.

Am J Hematol. 2019 May 31. doi: 10.1002/ajh.25543. [Epub ahead of print]

PMID:
31148215
3.

Elucidating Host Cell Uptake by Malaria Parasites.

Elsworth B, Keroack CD, Duraisingh MT.

Trends Parasitol. 2019 May;35(5):333-335. doi: 10.1016/j.pt.2019.03.005. Epub 2019 Apr 16.

PMID:
31003757
4.

Structure of Plasmodium falciparum Rh5-CyRPA-Ripr invasion complex.

Wong W, Huang R, Menant S, Hong C, Sandow JJ, Birkinshaw RW, Healer J, Hodder AN, Kanjee U, Tonkin CJ, Heckmann D, Soroka V, Søgaard TMM, Jørgensen T, Duraisingh MT, Czabotar PE, de Jongh WA, Tham WH, Webb AI, Yu Z, Cowman AF.

Nature. 2019 Jan;565(7737):118-121. doi: 10.1038/s41586-018-0779-6. Epub 2018 Dec 12.

PMID:
30542156
5.

To kill a piroplasm: genetic technologies to advance drug discovery and target identification in Babesia.

Keroack CD, Elsworth B, Duraisingh MT.

Int J Parasitol. 2019 Feb;49(2):153-163. doi: 10.1016/j.ijpara.2018.09.005. Epub 2018 Nov 1. Review.

PMID:
30391230
6.

Molecular and cellular interactions defining the tropism of Plasmodium vivax for reticulocytes.

Kanjee U, Rangel GW, Clark MA, Duraisingh MT.

Curr Opin Microbiol. 2018 Dec;46:109-115. doi: 10.1016/j.mib.2018.10.002. Epub 2018 Oct 23. Review.

PMID:
30366310
7.

Erythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite Plasmodium falciparum.

Egan ES, Weekes MP, Kanjee U, Manzo J, Srinivasan A, Lomas-Francis C, Westhoff C, Takahashi J, Tanaka M, Watanabe S, Brugnara C, Gygi SP, Tani Y, Duraisingh MT.

Commun Biol. 2018 May 3;1:45. doi: 10.1038/s42003-018-0046-2. eCollection 2018.

8.

Resistance to Plasmodium falciparum in sickle cell trait erythrocytes is driven by oxygen-dependent growth inhibition.

Archer NM, Petersen N, Clark MA, Buckee CO, Childs LM, Duraisingh MT.

Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):7350-7355. doi: 10.1073/pnas.1804388115. Epub 2018 Jun 26.

9.

Epigenetic Variation and Regulation in Malaria Parasites.

Duraisingh MT, Skillman KM.

Annu Rev Microbiol. 2018 Sep 8;72:355-375. doi: 10.1146/annurev-micro-090817-062722. Epub 2018 Jun 21. Review.

PMID:
29927705
10.

Bone Marrow Is a Major Parasite Reservoir in Plasmodium vivax Infection.

Obaldia N 3rd, Meibalan E, Sa JM, Ma S, Clark MA, Mejia P, Moraes Barros RR, Otero W, Ferreira MU, Mitchell JR, Milner DA, Huttenhower C, Wirth DF, Duraisingh MT, Wellems TE, Marti M.

MBio. 2018 May 8;9(3). pii: e00625-18. doi: 10.1128/mBio.00625-18.

11.

Enhanced Ex Vivo Plasmodium vivax Intraerythrocytic Enrichment and Maturation for Rapid and Sensitive Parasite Growth Assays.

Rangel GW, Clark MA, Kanjee U, Lim C, Shaw-Saliba K, Menezes MJ, Mascarenhas A, Chery L, Gomes E, Rathod PK, Ferreira MU, Duraisingh MT.

Antimicrob Agents Chemother. 2018 Mar 27;62(4). pii: e02519-17. doi: 10.1128/AAC.02519-17. Print 2018 Apr.

12.

Transferrin receptor 1 is a reticulocyte-specific receptor for Plasmodium vivax.

Gruszczyk J, Kanjee U, Chan LJ, Menant S, Malleret B, Lim NTY, Schmidt CQ, Mok YF, Lin KM, Pearson RD, Rangel G, Smith BJ, Call MJ, Weekes MP, Griffin MDW, Murphy JM, Abraham J, Sriprawat K, Menezes MJ, Ferreira MU, Russell B, Renia L, Duraisingh MT, Tham WH.

Science. 2018 Jan 5;359(6371):48-55. doi: 10.1126/science.aan1078.

13.

Targeting Plasmodium Proteases to Block Malaria Parasite Escape and Entry.

Paul AS, Duraisingh MT.

Trends Parasitol. 2018 Feb;34(2):95-97. doi: 10.1016/j.pt.2017.11.012. Epub 2017 Dec 18.

PMID:
29269028
14.

Malaria in India: The Need for New Targets for Diagnosis and Detection of Plasmodium vivax.

Patankar S, Sharma S, Rathod PK, Duraisingh MT.

Proteomics Clin Appl. 2018 Jul;12(4):e1700024. doi: 10.1002/prca.201700024. Epub 2018 Jan 11. Review.

15.

Lysophosphatidylcholine Regulates Sexual Stage Differentiation in the Human Malaria Parasite Plasmodium falciparum.

Brancucci NMB, Gerdt JP, Wang C, De Niz M, Philip N, Adapa SR, Zhang M, Hitz E, Niederwieser I, Boltryk SD, Laffitte MC, Clark MA, Grüring C, Ravel D, Blancke Soares A, Demas A, Bopp S, Rubio-Ruiz B, Conejo-Garcia A, Wirth DF, Gendaszewska-Darmach E, Duraisingh MT, Adams JH, Voss TS, Waters AP, Jiang RHY, Clardy J, Marti M.

Cell. 2017 Dec 14;171(7):1532-1544.e15. doi: 10.1016/j.cell.2017.10.020. Epub 2017 Nov 9.

16.

Molecular interactions governing host-specificity of blood stage malaria parasites.

Scully EJ, Kanjee U, Duraisingh MT.

Curr Opin Microbiol. 2017 Dec;40:21-31. doi: 10.1016/j.mib.2017.10.006. Epub 2017 Oct 31. Review.

17.

CRISPR/Cas9 knockouts reveal genetic interaction between strain-transcendent erythrocyte determinants of Plasmodium falciparum invasion.

Kanjee U, Grüring C, Chaand M, Lin KM, Egan E, Manzo J, Jones PL, Yu T, Barker R Jr, Weekes MP, Duraisingh MT.

Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):E9356-E9365. doi: 10.1073/pnas.1711310114. Epub 2017 Oct 19.

18.

The Molecular Basis of Erythrocyte Invasion by Malaria Parasites.

Cowman AF, Tonkin CJ, Tham WH, Duraisingh MT.

Cell Host Microbe. 2017 Aug 9;22(2):232-245. doi: 10.1016/j.chom.2017.07.003. Review.

19.

Genetic Evidence for Erythrocyte Receptor Glycophorin B Expression Levels Defining a Dominant Plasmodium falciparum Invasion Pathway into Human Erythrocytes.

Dankwa S, Chaand M, Kanjee U, Jiang RHY, Nobre LV, Goldberg JM, Bei AK, Moechtar MA, Grüring C, Ahouidi AD, Ndiaye D, Dieye TN, Mboup S, Weekes MP, Duraisingh MT.

Infect Immun. 2017 Sep 20;85(10). pii: e00074-17. doi: 10.1128/IAI.00074-17. Print 2017 Oct.

20.

PfCDPK1 mediated signaling in erythrocytic stages of Plasmodium falciparum.

Kumar S, Kumar M, Ekka R, Dvorin JD, Paul AS, Madugundu AK, Gilberger T, Gowda H, Duraisingh MT, Keshava Prasad TS, Sharma P.

Nat Commun. 2017 Jul 5;8(1):63. doi: 10.1038/s41467-017-00053-1.

21.

Functional Analysis Reveals Geographical Variation in Inhibitory Immune Responses Against a Polymorphic Malaria Antigen.

Bei AK, Ahouidi AD, Dvorin JD, Miura K, Diouf A, Ndiaye D, Premji Z, Diakite M, Mboup S, Long CA, Duraisingh MT.

J Infect Dis. 2017 Jul 15;216(2):267-275. doi: 10.1093/infdis/jix280.

22.

Erratum: Plasmodium falciparum CRK4 directs continuous rounds of DNA replication during schizogony.

Ganter M, Goldberg JM, Dvorin JD, Paulo JA, King JG, Tripathi AK, Paul AS, Yang J, Coppens I, Jiang RH, Elsworth B, Baker DA, Dinglasan RR, Gygi SP, Duraisingh MT.

Nat Microbiol. 2017 Mar 6;2:17038. doi: 10.1038/nmicrobiol.2017.38. No abstract available.

PMID:
28263306
23.

Host Cell Tropism and Adaptation of Blood-Stage Malaria Parasites: Challenges for Malaria Elimination.

Lim C, Dankwa S, Paul AS, Duraisingh MT.

Cold Spring Harb Perspect Med. 2017 Nov 1;7(11). pii: a025494. doi: 10.1101/cshperspect.a025494. Review.

PMID:
28213436
24.

Plasmodium falciparum CRK4 directs continuous rounds of DNA replication during schizogony.

Ganter M, Goldberg JM, Dvorin JD, Paulo JA, King JG, Tripathi AK, Paul AS, Yang J, Coppens I, Jiang RH, Elsworth B, Baker DA, Dinglasan RR, Gygi SP, Duraisingh MT.

Nat Microbiol. 2017 Feb 17;2:17017. doi: 10.1038/nmicrobiol.2017.17. Erratum in: Nat Microbiol. 2017 Mar 06;2:17038.

25.

Demographic and clinical profiles of Plasmodium falciparum and Plasmodium vivax patients at a tertiary care centre in southwestern India.

Chery L, Maki JN, Mascarenhas A, Walke JT, Gawas P, Almeida A, Fernandes M, Vaz M, Ramanan R, Shirodkar D, Bernabeu M, Manoharan SK, Pereira L, Dash R, Sharma A, Shaik RB, Chakrabarti R, Babar P, White J 3rd, Mudeppa DG, Kumar S, Zuo W, Skillman KM, Kanjee U, Lim C, Shaw-Saliba K, Kumar A, Valecha N, Jindal VN, Khandeparkar A, Naik P, Amonkar S, Duraisingh MT, Tuljapurkar S, Smith JD, Dubhashi N, Pinto RG, Silveria M, Gomes E, Rathod PK.

Malar J. 2016 Nov 25;15(1):569.

26.

Independent Origin and Global Distribution of Distinct Plasmodium vivax Duffy Binding Protein Gene Duplications.

Hostetler JB, Lo E, Kanjee U, Amaratunga C, Suon S, Sreng S, Mao S, Yewhalaw D, Mascarenhas A, Kwiatkowski DP, Ferreira MU, Rathod PK, Yan G, Fairhurst RM, Duraisingh MT, Rayner JC.

PLoS Negl Trop Dis. 2016 Oct 31;10(10):e0005091. doi: 10.1371/journal.pntd.0005091. eCollection 2016 Oct.

27.

Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria.

Mantel PY, Hjelmqvist D, Walch M, Kharoubi-Hess S, Nilsson S, Ravel D, Ribeiro M, Grüring C, Ma S, Padmanabhan P, Trachtenberg A, Ankarklev J, Brancucci NM, Huttenhower C, Duraisingh MT, Ghiran I, Kuo WP, Filgueira L, Martinelli R, Marti M.

Nat Commun. 2016 Oct 10;7:12727. doi: 10.1038/ncomms12727.

28.

Insights into an Optimization of Plasmodium vivax Sal-1 In Vitro Culture: The Aotus Primate Model.

Shaw-Saliba K, Thomson-Luque R, Obaldía N 3rd, Nuñez M, Dutary S, Lim C, Barnes S, Kocken CH, Duraisingh MT, Adams JH, Pasini EM.

PLoS Negl Trop Dis. 2016 Jul 27;10(7):e0004870. doi: 10.1371/journal.pntd.0004870. eCollection 2016 Jul.

29.

Distinct genomic architecture of Plasmodium falciparum populations from South Asia.

Kumar S, Mudeppa DG, Sharma A, Mascarenhas A, Dash R, Pereira L, Shaik RB, Maki JN, White J 3rd, Zuo W, Tuljapurkar S, Duraisingh MT, Gomes E, Chery L, Rathod PK.

Mol Biochem Parasitol. 2016 Nov - Dec;210(1-2):1-4. doi: 10.1016/j.molbiopara.2016.07.005. Epub 2016 Jul 22.

30.

Infection of laboratory colonies of Anopheles mosquitoes with Plasmodium vivax from cryopreserved clinical isolates.

Shaw-Saliba K, Clarke D, Santos JM, Menezes MJ, Lim C, Mascarenhas A, Chery L, Gomes E, March S, Bhatia SN, Rathod PK, Ferreira MU, Catteruccia F, Duraisingh MT.

Int J Parasitol. 2016 Oct;46(11):679-83. doi: 10.1016/j.ijpara.2016.06.003. Epub 2016 Jul 25.

31.

Reticulocyte Preference and Stage Development of Plasmodium vivax Isolates.

Lim C, Pereira L, Saliba KS, Mascarenhas A, Maki JN, Chery L, Gomes E, Rathod PK, Duraisingh MT.

J Infect Dis. 2016 Oct 1;214(7):1081-4. doi: 10.1093/infdis/jiw303. Epub 2016 Jul 17.

32.

Extensive Shared Chemosensitivity between Malaria and Babesiosis Blood-Stage Parasites.

Paul AS, Moreira CK, Elsworth B, Allred DR, Duraisingh MT.

Antimicrob Agents Chemother. 2016 Jul 22;60(8):5059-63. doi: 10.1128/AAC.00928-16. Print 2016 Aug.

33.

Epigenetic Regulation of Virulence Gene Expression in Parasitic Protozoa.

Duraisingh MT, Horn D.

Cell Host Microbe. 2016 May 11;19(5):629-40. doi: 10.1016/j.chom.2016.04.020. Review.

34.

Improved light microscopy counting method for accurately counting Plasmodium parasitemia and reticulocytemia.

Lim C, Pereira L, Shardul P, Mascarenhas A, Maki J, Rixon J, Shaw-Saliba K, White J, Silveira M, Gomes E, Chery L, Rathod PK, Duraisingh MT.

Am J Hematol. 2016 Aug;91(8):852-5. doi: 10.1002/ajh.24383. Epub 2016 May 24.

35.

Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite.

Dankwa S, Lim C, Bei AK, Jiang RH, Abshire JR, Patel SD, Goldberg JM, Moreno Y, Kono M, Niles JC, Duraisingh MT.

Nat Commun. 2016 Apr 4;7:11187. doi: 10.1038/ncomms11187.

36.

Using a Genetically Encoded Sensor to Identify Inhibitors of Toxoplasma gondii Ca2+ Signaling.

Sidik SM, Hortua Triana MA, Paul AS, El Bakkouri M, Hackett CG, Tran F, Westwood NJ, Hui R, Zuercher WJ, Duraisingh MT, Moreno SN, Lourido S.

J Biol Chem. 2016 Apr 29;291(18):9566-80. doi: 10.1074/jbc.M115.703546. Epub 2016 Mar 1.

37.

Evidence for spleen dysfunction in malaria-HIV co-infection in a subset of pediatric patients.

Joice R, Frantzreb C, Pradham A, Seydel KB, Kamiza S, Wirth DF, Duraisingh MT, Molyneux ME, Taylor TE, Marti M, Milner DA Jr.

Mod Pathol. 2016 Apr;29(4):381-90. doi: 10.1038/modpathol.2016.27. Epub 2016 Feb 26.

38.

Altered drug susceptibility during host adaptation of a Plasmodium falciparum strain in a non-human primate model.

Obaldía N 3rd, Dow GS, Gerena L, Kyle D, Otero W, Mantel PY, Baro N, Daniels R, Mukherjee A, Childs LM, Buckee C, Duraisingh MT, Volkman SK, Wirth DF, Marti M.

Sci Rep. 2016 Feb 16;6:21216. doi: 10.1038/srep21216.

39.

Malaria Vaccine Development: Focusing Field Erythrocyte Invasion Studies on Phenotypic Diversity: The West African Merozoite Invasion Network (WAMIN).

WAMIN consortium authors include (in alphabetical order):, Ahouidi AD, Amambua-Ngwa A, Awandare GA, Bei AK, Conway DJ, Diakite M, Duraisingh MT, Rayner JC, Zenonos ZA.

Trends Parasitol. 2016 Apr;32(4):274-283. doi: 10.1016/j.pt.2015.11.009. Epub 2015 Dec 23. Review.

PMID:
26725306
40.

The Clinically Tested Gardos Channel Inhibitor Senicapoc Exhibits Antimalarial Activity.

Tubman VN, Mejia P, Shmukler BE, Bei AK, Alper SL, Mitchell JR, Brugnara C, Duraisingh MT.

Antimicrob Agents Chemother. 2015 Oct 12;60(1):613-6. doi: 10.1128/AAC.01668-15. Print 2016 Jan.

41.

Measuring Plasmodium falciparum Erythrocyte Invasion Phenotypes Using Flow Cytometry.

Bei AK, Duraisingh MT.

Methods Mol Biol. 2015;1325:167-86. doi: 10.1007/978-1-4939-2815-6_14.

PMID:
26450388
42.

Population genomic structure and adaptation in the zoonotic malaria parasite Plasmodium knowlesi.

Assefa S, Lim C, Preston MD, Duffy CW, Nair MB, Adroub SA, Kadir KA, Goldberg JM, Neafsey DE, Divis P, Clark TG, Duraisingh MT, Conway DJ, Pain A, Singh B.

Proc Natl Acad Sci U S A. 2015 Oct 20;112(42):13027-32. doi: 10.1073/pnas.1509534112. Epub 2015 Oct 5.

43.

Investigating the Pathogenesis of Severe Malaria: A Multidisciplinary and Cross-Geographical Approach.

Wassmer SC, Taylor TE, Rathod PK, Mishra SK, Mohanty S, Arevalo-Herrera M, Duraisingh MT, Smith JD.

Am J Trop Med Hyg. 2015 Sep;93(3 Suppl):42-56. doi: 10.4269/ajtmh.14-0841. Epub 2015 Aug 10. Review.

44.

Parasite Calcineurin Regulates Host Cell Recognition and Attachment by Apicomplexans.

Paul AS, Saha S, Engelberg K, Jiang RH, Coleman BI, Kosber AL, Chen CT, Ganter M, Espy N, Gilberger TW, Gubbels MJ, Duraisingh MT.

Cell Host Microbe. 2015 Jul 8;18(1):49-60. doi: 10.1016/j.chom.2015.06.003. Epub 2015 Jun 25.

45.

Malaria. A forward genetic screen identifies erythrocyte CD55 as essential for Plasmodium falciparum invasion.

Egan ES, Jiang RH, Moechtar MA, Barteneva NS, Weekes MP, Nobre LV, Gygi SP, Paulo JA, Frantzreb C, Tani Y, Takahashi J, Watanabe S, Goldberg J, Paul AS, Brugnara C, Root DE, Wiegand RC, Doench JG, Duraisingh MT.

Science. 2015 May 8;348(6235):711-4. doi: 10.1126/science.aaa3526.

46.

Functional analysis of sirtuin genes in multiple Plasmodium falciparum strains.

Merrick CJ, Jiang RH, Skillman KM, Samarakoon U, Moore RM, Dzikowski R, Ferdig MT, Duraisingh MT.

PLoS One. 2015 Mar 17;10(3):e0118865. doi: 10.1371/journal.pone.0118865. eCollection 2015.

47.

Host-parasite interactions that guide red blood cell invasion by malaria parasites.

Paul AS, Egan ES, Duraisingh MT.

Curr Opin Hematol. 2015 May;22(3):220-6. doi: 10.1097/MOH.0000000000000135. Review.

48.

From Protease to Decarboxylase: THE MOLECULAR METAMORPHOSIS OF PHOSPHATIDYLSERINE DECARBOXYLASE.

Choi JY, Duraisingh MT, Marti M, Ben Mamoun C, Voelker DR.

J Biol Chem. 2015 Apr 24;290(17):10972-80. doi: 10.1074/jbc.M115.642413. Epub 2015 Feb 26.

49.

Dietary restriction protects against experimental cerebral malaria via leptin modulation and T-cell mTORC1 suppression.

Mejia P, Treviño-Villarreal JH, Hine C, Harputlugil E, Lang S, Calay E, Rogers R, Wirth D, Duraisingh MT, Mitchell JR.

Nat Commun. 2015 Jan 30;6:6050. doi: 10.1038/ncomms7050.

50.

Enrichment of reticulocytes from whole blood using aqueous multiphase systems of polymers.

Kumar AA, Lim C, Moreno Y, Mace CR, Syed A, Van Tyne D, Wirth DF, Duraisingh MT, Whitesides GM.

Am J Hematol. 2015 Jan;90(1):31-6. doi: 10.1002/ajh.23860. Epub 2014 Oct 18.

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