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Items: 10


Absence of MHC-II expression by lymph node stromal cells results in autoimmunity.

Dubrot J, Duraes FV, Harlé G, Schlaeppi A, Brighouse D, Madelon N, Göpfert C, Stokar-Regenscheit N, Acha-Orbea H, Reith W, Gannagé M, Hugues S.

Life Sci Alliance. 2018 Dec 17;1(6):e201800164. doi: 10.26508/lsa.201800164. eCollection 2018 Dec.


IDO-orchestrated crosstalk between pDCs and Tregs inhibits autoimmunity.

Lippens C, Duraes FV, Dubrot J, Brighouse D, Lacroix M, Irla M, Aubry-Lachainaye JP, Reith W, Mandl JN, Hugues S.

J Autoimmun. 2016 Dec;75:39-49. doi: 10.1016/j.jaut.2016.07.004. Epub 2016 Jul 26.


Macroautophagy in Endogenous Processing of Self- and Pathogen-Derived Antigens for MHC Class II Presentation.

Duraes FV, Niven J, Dubrot J, Hugues S, Gannagé M.

Front Immunol. 2015 Sep 22;6:459. doi: 10.3389/fimmu.2015.00459. eCollection 2015. Review.


pDC therapy induces recovery from EAE by recruiting endogenous pDC to sites of CNS inflammation.

Duraes FV, Lippens C, Steinbach K, Dubrot J, Brighouse D, Bendriss-Vermare N, Issazadeh-Navikas S, Merkler D, Hugues S.

J Autoimmun. 2016 Feb;67:8-18. doi: 10.1016/j.jaut.2015.08.014. Epub 2015 Sep 1.


Lymph node stromal cells acquire peptide-MHCII complexes from dendritic cells and induce antigen-specific CD4⁺ T cell tolerance.

Dubrot J, Duraes FV, Potin L, Capotosti F, Brighouse D, Suter T, LeibundGut-Landmann S, Garbi N, Reith W, Swartz MA, Hugues S.

J Exp Med. 2014 Jun 2;211(6):1153-66. doi: 10.1084/jem.20132000. Epub 2014 May 19.


Role of major histocompatibility complex class II expression by non-hematopoietic cells in autoimmune and inflammatory disorders: facts and fiction.

Duraes FV, Thelemann C, Sarter K, Acha-Orbea H, Hugues S, Reith W.

Tissue Antigens. 2013 Jul;82(1):1-15. doi: 10.1111/tan.12136. Review.


VEGF-C promotes immune tolerance in B16 melanomas and cross-presentation of tumor antigen by lymph node lymphatics.

Lund AW, Duraes FV, Hirosue S, Raghavan VR, Nembrini C, Thomas SN, Issa A, Hugues S, Swartz MA.

Cell Rep. 2012 Mar 29;1(3):191-9. doi: 10.1016/j.celrep.2012.01.005. Epub 2012 Feb 23.


Toll-like receptor 9 is required for full host resistance to Mycobacterium avium infection but plays no role in induction of Th1 responses.

Carvalho NB, Oliveira FS, Durães FV, de Almeida LA, Flórido M, Prata LO, Caliari MV, Appelberg R, Oliveira SC.

Infect Immun. 2011 Apr;79(4):1638-46. doi: 10.1128/IAI.01030-10. Epub 2011 Feb 7.


Recruitment of CD8(+) T cells expressing granzyme A is associated with lesion progression in human cutaneous leishmaniasis.

Faria DR, Souza PE, Durães FV, Carvalho EM, Gollob KJ, Machado PR, Dutra WO.

Parasite Immunol. 2009 Aug;31(8):432-9. doi: 10.1111/j.1365-3024.2009.01125.x.


IL-12 and TNF-alpha production by dendritic cells stimulated with Schistosoma mansoni schistosomula tegument is TLR4- and MyD88-dependent.

Durães FV, Carvalho NB, Melo TT, Oliveira SC, Fonseca CT.

Immunol Lett. 2009 Jun 30;125(1):72-7. doi: 10.1016/j.imlet.2009.06.004. Epub 2009 Jun 17.


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