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Personalised mechanical ventilation tailored to lung morphology versus low positive end-expiratory pressure for patients with acute respiratory distress syndrome in France (the LIVE study): a multicentre, single-blind, randomised controlled trial.

Constantin JM, Jabaudon M, Lefrant JY, Jaber S, Quenot JP, Langeron O, Ferrandière M, Grelon F, Seguin P, Ichai C, Veber B, Souweine B, Uberti T, Lasocki S, Legay F, Leone M, Eisenmann N, Dahyot-Fizelier C, Dupont H, Asehnoune K, Sossou A, Chanques G, Muller L, Bazin JE, Monsel A, Borao L, Garcier JM, Rouby JJ, Pereira B, Futier E; AZUREA Network.

Lancet Respir Med. 2019 Aug 6. pii: S2213-2600(19)30138-9. doi: 10.1016/S2213-2600(19)30138-9. [Epub ahead of print]


Escape game training to improve non-technical team skills in the operating room.

Terrasi B, Badoux L, Abou Arab O, Huette P, Bar S, Leviel F, Amsallem C, Ammirati C, Dupont H, Lorne E.

Med Teach. 2019 Jul 14:1. doi: 10.1080/0142159X.2019.1638505. [Epub ahead of print] No abstract available.


[Alcohol consumption : from epidemiology to prevention].

Streel S, Silvestre A, Hoge A, Guillaume M, Donneau AF, Dupont H, Pétré B.

Rev Med Liege. 2019 May;74(5-6):241-247. French.


Use of the Smartphone App WhatsApp as an E-Learning Method for Medical Residents: Multicenter Controlled Randomized Trial.

Clavier T, Ramen J, Dureuil B, Veber B, Hanouz JL, Dupont H, Lebuffe G, Besnier E, Compere V.

JMIR Mhealth Uhealth. 2019 Apr 9;7(4):e12825. doi: 10.2196/12825.


Clostridium difficile Modulates the Gut Microbiota by Inducing the Production of Indole, an Interkingdom Signaling and Antimicrobial Molecule.

Darkoh C, Plants-Paris K, Bishoff D, DuPont HL.

mSystems. 2019 Mar 19;4(2). pii: e00346-18. doi: 10.1128/mSystems.00346-18. eCollection 2019 Mar-Apr.


Fecal calprotectin and fecal indole predict outcome of fecal microbiota transplantation in subjects with recurrent Clostridium difficile infection.

Hibbard J, Jiang ZD, DuPont HL.

Anaerobe. 2019 Apr;56:102-105. doi: 10.1016/j.anaerobe.2019.03.006. Epub 2019 Mar 6.


Rifamycin SV-MMX® as the recommended self-treatment for moderate to severe travellers' diarrhoea: reply.

Steffen R, DuPont HL.

J Travel Med. 2019 May 10;26(3). pii: taz014. doi: 10.1093/jtm/taz014. No abstract available.


Antibioprophylaxis in surgery and interventional medicine (adult patients). Update 2017.

Martin C, Auboyer C, Boisson M, Dupont H, Gauzit R, Kitzis M, Leone M, Lepape A, Mimoz O, Montravers P, Pourriat JL; Steering committee of the French Society of Anaesthesia and Intensive Care Medicine (SFAR) responsible for the establishment of the guidelines.

Anaesth Crit Care Pain Med. 2019 Mar 2. pii: S2352-5568(19)30085-2. doi: 10.1016/j.accpm.2019.02.017. [Epub ahead of print]


Influence of bacterial resistance on mortality in intensive care units: a registry study from 2000 to 2013 (IICU Study).

Bonnet V, Dupont H, Glorion S, Aupée M, Kipnis E, Gérard JL, Hanouz JL, Fischer MO.

J Hosp Infect. 2019 Jul;102(3):317-324. doi: 10.1016/j.jhin.2019.01.011. Epub 2019 Jan 17.


Occurrence of putative virulence-related genes, aatA, aggR and aaiC, of Enteroaggregative Escherichia coli (EAEC) among adults with travelers' diarrhea acquired in Guatemala and Mexico.

Bamidele O, Jiang ZD, Dupont H.

Microb Pathog. 2019 Mar;128:97-99. doi: 10.1016/j.micpath.2018.12.030. Epub 2018 Dec 21.


Erratum to "Storage at room temperature does not change cisatracurium onset time: A prospective, randomized, double-blind controlled study [Ann. Fr. Anesth. Reanim. 31 (2012) 783-787].

Lorne E, Nuzzo D, Suzanne S, Walczak KA, Perret C, Laigle C, Mattei N, Dimov E, Petiot S, Godart J, Pila C, Verdier MC, Chourbagi C, Diouf M, Friggeri A, Mahjoub Y, Dupont H.

Anaesth Crit Care Pain Med. 2018 Dec;37(6):653. doi: 10.1016/j.accpm.2018.10.012. No abstract available.


Estimating the incidence of norovirus acute gastroenteritis among US and European international travelers to areas of moderate to high risk of traveler's diarrhea: a prospective cohort study protocol.

Lindsay L, DuPont HL, Moe CL, Alberer M, Hatz C, Kirby AE, Wu HM, Verstraeten T, Steffen R.

BMC Infect Dis. 2018 Dec 3;18(1):605. doi: 10.1186/s12879-018-3461-6.


Author Correction: Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis.

Wang Y, Wiesnoski DH, Helmink BA, Gopalakrishnan V, Choi K, DuPont HL, Jiang ZD, Abu-Sbeih H, Sanchez CA, Chang CC, Parra ER, Francisco-Cruz A, Raju GS, Stroehlein JR, Campbell MT, Gao J, Subudhi SK, Maru DM, Blando JM, Lazar AJ, Allison JP, Sharma P, Tetzlaff MT, Wargo JA, Jenq RR.

Nat Med. 2019 Jan;25(1):188. doi: 10.1038/s41591-018-0305-2.


Rifamycin SV-MMX® for treatment of travellers' diarrhea: equally effective as ciprofloxacin and not associated with the acquisition of multi-drug resistant bacteria.

Steffen R, Jiang ZD, Gracias Garcia ML, Araujo P, Stiess M, Nacak T, Greinwald R, DuPont HL.

J Travel Med. 2018 Jan 1;25(1). doi: 10.1093/jtm/tay116.


Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis.

Wang Y, Wiesnoski DH, Helmink BA, Gopalakrishnan V, Choi K, DuPont HL, Jiang ZD, Abu-Sbeih H, Sanchez CA, Chang CC, Parra ER, Francisco-Cruz A, Raju GS, Stroehlein JR, Campbell MT, Gao J, Subudhi SK, Maru DM, Blando JM, Lazar AJ, Allison JP, Sharma P, Tetzlaff MT, Wargo JA, Jenq RR.

Nat Med. 2018 Dec;24(12):1804-1808. doi: 10.1038/s41591-018-0238-9. Epub 2018 Nov 12. Erratum in: Nat Med. 2018 Nov 27;:.


Visualization-assisted binning of metagenome assemblies reveals potential new pathogenic profiles in idiopathic travelers' diarrhea.

Zhu Q, Dupont CL, Jones MB, Pham KM, Jiang ZD, DuPont HL, Highlander SK.

Microbiome. 2018 Nov 8;6(1):201. doi: 10.1186/s40168-018-0579-0.


Safety and preliminary efficacy of orally administered lyophilized fecal microbiota product compared with frozen product given by enema for recurrent Clostridium difficile infection: A randomized clinical trial.

Jiang ZD, Jenq RR, Ajami NJ, Petrosino JF, Alexander AA, Ke S, Iqbal T, DuPont AW, Muldrew K, Shi Y, Peterson C, Do KA, DuPont HL.

PLoS One. 2018 Nov 2;13(11):e0205064. doi: 10.1371/journal.pone.0205064. eCollection 2018.


The predictability of dynamic preload indices depends on the volume of fluid challenge: A prospective observational study in the operating theater.

Guinot PG, Marc J, de Broca B, Archange T, Bar S, Abou-Arab O, Dupont H, Fischer MO, Lorne E.

Medicine (Baltimore). 2018 Oct;97(42):e12848. doi: 10.1097/MD.0000000000012848.


Fatal Fusobacterium necrophorum infection with gynecological Lemierre's syndrome.

Reymond B, Huette P, Roger PA, Tredez E, Gagneur O, Sanguin S, Guihéneuf R, Dupont H, Mahjoub Y, Abou Arab O.

Med Mal Infect. 2019 Feb;49(1):72-74. doi: 10.1016/j.medmal.2018.09.006. Epub 2018 Oct 9. No abstract available.


Evaluation of Escherichia coli pathotypes associated with irritable bowel syndrome.

Dogan B, Belcher-Timme HF, Dogan EI, Jiang ZD, DuPont HL, Snyder N, Yang S, Chandler B, Scherl EJ, Simpson KW.

FEMS Microbiol Lett. 2018 Nov 1;365(22). doi: 10.1093/femsle/fny249.


Non-O157 Shiga toxin-producing Escherichia coli-A poorly appreciated enteric pathogen: Systematic review.

Valilis E, Ramsey A, Sidiq S, DuPont HL.

Int J Infect Dis. 2018 Nov;76:82-87. doi: 10.1016/j.ijid.2018.09.002. Epub 2018 Sep 14.


The relationship between sex hormones, the vaginal microbiome and immunity in HIV-1 susceptibility in women.

Wessels JM, Felker AM, Dupont HA, Kaushic C.

Dis Model Mech. 2018 Aug 28;11(9). pii: dmm035147. doi: 10.1242/dmm.035147. Review.


Outcomes after extracorporeal membrane oxygenation for the treatment of high-risk pulmonary embolism: a multicentre series of 52 cases.

Meneveau N, Guillon B, Planquette B, Piton G, Kimmoun A, Gaide-Chevronnay L, Aissaoui N, Neuschwander A, Zogheib E, Dupont H, Pili-Floury S, Ecarnot F, Schiele F, Deye N, de Prost N, Favory R, Girard P, Cristinar M, Ferré A, Meyer G, Capellier G, Sanchez O.

Eur Heart J. 2018 Dec 14;39(47):4196-4204. doi: 10.1093/eurheartj/ehy464.


Dynamic arterial elastance might not be an indicator of ventriculo-arterial coupling. Comment on Br J Anaesth 2017; 118: 938-46.

Bar S, Huette P, Abou-Arab O, Dupont H, Lorne E, Guinot PG.

Br J Anaesth. 2018 Sep;121(3):672-673. doi: 10.1016/j.bja.2018.03.027. Epub 2018 Apr 24. No abstract available.


Dynamic arterial elastance measured by uncalibrated pulse contour analysis predicts arterial-pressure response to a decrease in norepinephrine.

Bar S, Leviel F, Abou Arab O, Badoux L, Mahjoub Y, Dupont H, Lorne E, Guinot PG.

Br J Anaesth. 2018 Sep;121(3):534-540. doi: 10.1016/j.bja.2018.01.032. Epub 2018 Mar 7.


Multicenter performance evaluation of the Unyvero IAI cartridge for detection of intra-abdominal infections.

Ciesielczuk H, Wilks M, Castelain S, Choquet M, Morotti M, Pluquet E, Sambri V, Tassinari M, Zannoli S, Cavalié L, Dupont H, Guet-Revillet H.

Eur J Clin Microbiol Infect Dis. 2018 Nov;37(11):2107-2115. doi: 10.1007/s10096-018-3345-0. Epub 2018 Aug 10.


Search for the optimal antimicrobial therapy of Clostridium difficile infection.

DuPont HL.

Lancet Infect Dis. 2018 Sep;18(9):936-937. doi: 10.1016/S1473-3099(18)30308-6. Epub 2018 Jul 17. No abstract available.


Hormonal influence on HIV-1 transmission in the female genital tract: New insights from systems biology.

Dupont HA, Lam J, Woods MW, Zahoor MA, Kaushic C.

Am J Reprod Immunol. 2018 Aug;80(2):e13019. doi: 10.1111/aji.13019. Epub 2018 Jul 16.


High rate of Clostridium difficile among young adults presenting with diarrhea at two hospitals in Kenya.

Oyaro MO, Plants-Paris K, Bishoff D, Malonza P, Gontier CS, DuPont HL, Darkoh C.

Int J Infect Dis. 2018 Sep;74:24-28. doi: 10.1016/j.ijid.2018.06.014. Epub 2018 Jun 28.


New concepts on intestinal microbiota and the role of the non-absorbable antibiotics with special reference to rifaximin in digestive diseases.

Bajaj JS, Barbara G, DuPont HL, Mearin F, Gasbarrini A, Tack J.

Dig Liver Dis. 2018 Aug;50(8):741-749. doi: 10.1016/j.dld.2018.04.020. Epub 2018 Apr 27. Review.


Distinguishing fecal appendicular peritonitis from purulent appendicular peritonitis.

Mariage M, Sabbagh C, Yzet T, Dupont H, NTouba A, Regimbeau JM.

Am J Emerg Med. 2018 Dec;36(12):2232-2235. doi: 10.1016/j.ajem.2018.04.014. Epub 2018 Apr 9.


The presence of elastic compression stockings reduces the fluid responsiveness of patients in the operating room.

Zogheib E, Maizel J, Cherradi N, Benammar A, Labont B, Hchikat A, Bernasinski M, Trojette F, Slama M, Dupont H.

Minerva Anestesiol. 2018 Nov;84(11):1279-1286. doi: 10.23736/S0375-9393.18.12461-8. Epub 2018 May 11.


Impact of combined antibiotic treatment on multidrug-resistant bacteria emergence after postoperative intra-abdominal infections : Discussion on the DURAPOP randomised clinical trial.

Simeone P, Lagier D, Mokart D, Montravers P, Esposito-Farèse M, Lasocki S, Dupont H.

Intensive Care Med. 2018 Jun;44(6):1000-1001. doi: 10.1007/s00134-018-5215-8. Epub 2018 May 12. No abstract available.


Biological scoring system for early prediction of acute bowel ischemia after cardiac surgery: the PALM score.

Zogheib E, Cosse C, Sabbagh C, Marx S, Caus T, Henry M, Nader J, Fumery M, Bernasinski M, Besserve P, Trojette F, Renard C, Duhaut P, Kamel S, Regimbeau JM, Dupont H.

Ann Intensive Care. 2018 Apr 18;8(1):46. doi: 10.1186/s13613-018-0395-5.


Determinants of amikacin first peak concentration in critically ill patients.

Boidin C, Jenck S, Bourguignon L, Torkmani S, Roussey-Jean A, Ledochowski S, Marry L, Ammenouche N, Dupont H, Marçon F, Allaouchiche B, Bohé J, Lepape A, Goutelle S, Friggeri A.

Fundam Clin Pharmacol. 2018 Dec;32(6):669-677. doi: 10.1111/fcp.12374. Epub 2018 May 23.


Is very short-course antibiotic therapy possible in postoperative intra-abdominal infections? Discussion on "Short-course antibiotic therapy for critically ill patients treated for postoperative intra-abdominal infection: the DURAPOP randomised clinical trial".

Suarez-de-la-Rica A, Gilsanz F, Maseda E, Montravers P, Lasocki S, Lescot T, Dupont H.

Intensive Care Med. 2018 May;44(5):695-696. doi: 10.1007/s00134-018-5167-z. Epub 2018 Apr 13. No abstract available.


Postoperative Vasoplegic Syndrome Is Associated With Impaired Endothelial Vasomotor Response in Cardiac Surgery: A Prospective, Observational Study.

Abou-Arab O, Martineau L, Bar S, Huette P, Amar AB, Caus T, Dupont H, Kamel S, Guinot PG, Lorne E.

J Cardiothorac Vasc Anesth. 2018 Oct;32(5):2218-2224. doi: 10.1053/j.jvca.2018.02.006. Epub 2018 Feb 6.


Short-course antibiotic therapy for critically ill patients treated for postoperative intra-abdominal infection: the DURAPOP randomised clinical trial.

Montravers P, Tubach F, Lescot T, Veber B, Esposito-Farèse M, Seguin P, Paugam C, Lepape A, Meistelman C, Cousson J, Tesniere A, Plantefeve G, Blasco G, Asehnoune K, Jaber S, Lasocki S, Dupont H; DURAPOP Trial Group.

Intensive Care Med. 2018 Mar;44(3):300-310. doi: 10.1007/s00134-018-5088-x. Epub 2018 Feb 26.


Gastric Acid and Enteric Infections: Souring on the Use of PPIs.

DuPont HL.

Dig Dis Sci. 2018 Apr;63(4):814-817. doi: 10.1007/s10620-018-4955-1. No abstract available.


The authors reply.

Dupont H, Mahjoub Y, Chouaki T, Lorne E, Zogheib E.

Crit Care Med. 2018 Feb;46(2):e174-e175. doi: 10.1097/CCM.0000000000002860. No abstract available.


Prospective Observational Study on the Association Between Serum Mannose-Binding Lectin Levels and Severe Outcome in Critically Ill Patients with Pandemic Influenza Type A (H1N1) Infection.

Zogheib E, Nyga R, Cornu M, Sendid B, Monconduit J, Jounieaux V, Maizel J, Segard C, Chouaki T, Dupont H.

Lung. 2018 Feb;196(1):65-72. doi: 10.1007/s00408-017-0067-5. Epub 2017 Dec 22.


Population pharmacokinetic evaluation of ADV6209, an innovative oral solution of midazolam containing cyclodextrin.

Marçon F, Guittet C, Manso MA, Burton I, Granier LA, Jacqmin P, Dupont H.

Eur J Pharm Sci. 2018 Mar 1;114:46-54. doi: 10.1016/j.ejps.2017.11.030. Epub 2017 Dec 5.


Thoracic Epidural Analgesia and Mortality in Acute Pancreatitis: A Multicenter Propensity Analysis.

Jabaudon M, Belhadj-Tahar N, Rimmelé T, Joannes-Boyau O, Bulyez S, Lefrant JY, Malledant Y, Leone M, Abback PS, Tamion F, Dupont H, Lortat-Jacob B, Guerci P, Kerforne T, Cinotti R, Jacob L, Verdier P, Dugernier T, Pereira B, Constantin JM; Azurea Network.

Crit Care Med. 2018 Mar;46(3):e198-e205. doi: 10.1097/CCM.0000000000002874.


Effectiveness of a blended learning course and flipped classroom in first year anaesthesia training.

Marchalot A, Dureuil B, Veber B, Fellahi JL, Hanouz JL, Dupont H, Lorne E, Gerard JL, Compère V.

Anaesth Crit Care Pain Med. 2018 Oct;37(5):411-415. doi: 10.1016/j.accpm.2017.10.008. Epub 2017 Nov 22.


Erratum for Darkoh et al., "Accessory Gene Regulator-1 Locus Is Essential for Virulence and Pathogenesis of Clostridium difficile".

Darkoh C, Odo C, DuPont HL.

MBio. 2017 Oct 31;8(5). pii: e01643-17. doi: 10.1128/mBio.01643-17. No abstract available.


Comment: Rifampin-Resistant Staphylococcus aureus Bacteremia in a Patient on Chronic Rifaximin.

DuPont HL, Bajaj JS.

Ann Pharmacother. 2018 Jan;52(1):94-95. doi: 10.1177/1060028017738263. Epub 2017 Oct 25. No abstract available.


Ventriculo-Arterial Coupling Analysis Predicts the Hemodynamic Response to Norepinephrine in Hypotensive Postoperative Patients: A Prospective Observational Study.

Guinot PG, Longrois D, Kamel S, Lorne E, Dupont H.

Crit Care Med. 2018 Jan;46(1):e17-e25. doi: 10.1097/CCM.0000000000002772.


Clinical features and molecular epidemiology of diarrheagenic Escherichia coli pathotypes identified by fecal gastrointestinal multiplex nucleic acid amplification in patients with cancer and diarrhea.

Chao AW, Bhatti M, DuPont HL, Nataro JP, Carlin LG, Okhuysen PC.

Diagn Microbiol Infect Dis. 2017 Nov;89(3):235-240. doi: 10.1016/j.diagmicrobio.2017.08.004. Epub 2017 Aug 12.


Antifungal Prevention of Systemic Candidiasis in Immunocompetent ICU Adults: Systematic Review and Meta-Analysis of Clinical Trials.

Dupont H, Mahjoub Y, Chouaki T, Lorne E, Zogheib E.

Crit Care Med. 2017 Nov;45(11):1937-1945. doi: 10.1097/CCM.0000000000002698. Review.


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