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Increased levels of the megakaryocyte and platelet expressed cysteine proteases stefin A and cystatin A prevent thrombosis.

Mezzapesa A, Bastelica D, Crescence L, Poggi M, Grino M, Peiretti F, Panicot-Dubois L, Dupont A, Valero R, Maraninchi M, Bordet JC, Alessi MC, Dubois C, Canault M.

Sci Rep. 2019 Jul 3;9(1):9631. doi: 10.1038/s41598-019-45805-9.


Investigation of the Role of AT2 Receptors in the Nucleus Tractus Solitarii of Normotensive Rats in Blood Pressure Control.

Légat L, Smolders IJ, Dupont AG.

Front Neurosci. 2019 Jun 5;13:589. doi: 10.3389/fnins.2019.00589. eCollection 2019.


AT1 Receptor Mediated Hypertensive Response to Ang II in the Nucleus Tractus Solitarii of Normotensive Rats Involves NO Dependent Local GABA Release.

Légat L, Smolders I, Dupont AG.

Front Pharmacol. 2019 May 3;10:460. doi: 10.3389/fphar.2019.00460. eCollection 2019.


Decompressive Craniectomy in Children with Severe Traumatic Brain Injury: A Multicenter Retrospective Study and Literature Review.

Manfiotto M, Beccaria K, Rolland A, Paternoster G, Plas B, Boetto S, Vinchon M, Mottolese C, Beuriat PA, Szathmari A, Di Rocco F, Scavarda D, Seigneuret E, Wrobleski I, Klein O, Joud A, Gimbert E, Jecko V, Vignes JR, Roujeau T, Dupont A, Zerah M, Lonjon M.

World Neurosurg. 2019 May 1. pii: S1878-8750(19)31211-2. doi: 10.1016/j.wneu.2019.04.215. [Epub ahead of print]


Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation.

Maurel M, Obacz J, Avril T, Ding YP, Papadodima O, Treton X, Daniel F, Pilalis E, Hörberg J, Hou W, Beauchamp MC, Tourneur-Marsille J, Cazals-Hatem D, Sommerova L, Samali A, Tavernier J, Hrstka R, Dupont A, Fessart D, Delom F, Fernandez-Zapico ME, Jansen G, Eriksson LA, Thomas DY, Jerome-Majewska L, Hupp T, Chatziioannou A, Chevet E, Ogier-Denis E.

EMBO Mol Med. 2019 Jun;11(6). pii: e10120. doi: 10.15252/emmm.201810120.


Improved Outcomes Associated with the use of Shock Protocols: Updates from the National Cardiogenic Shock Initiative.

Basir MB, Kapur NK, Patel K, Salam MA, Schreiber T, Kaki A, Hanson I, Almany S, Timmis S, Dixon S, Kolski B, Todd J, Senter S, Marso S, Lasorda D, Wilkins C, Lalonde T, Attallah A, Larkin T, Dupont A, Marshall J, Patel N, Overly T, Green M, Tehrani B, Truesdell AG, Sharma R, Akhtar Y, McRae T 3rd, O'Neill B, Finley J, Rahman A, Foster M, Askari R, Goldsweig A, Martin S, Bharadwaj A, Khuddus M, Caputo C, Korpas D, Cawich I, McAllister D, Blank N, Alraies MC, Fisher R, Khandelwal A, Alaswad K, Lemor A, Johnson T, Hacala M, O'Neill WW; National Cardiogenic Shock Initiative Investigators.

Catheter Cardiovasc Interv. 2019 Jun 1;93(7):1173-1183. doi: 10.1002/ccd.28307. Epub 2019 Apr 25.


Synthetic Anti-lipopolysaccharide Peptides (SALPs) as Effective Inhibitors of Pathogen-Associated Molecular Patterns (PAMPs).

Correa W, Heinbockel L, Martinez-de-Tejada G, Sánchez S, Garidel P, Schürholz T, Mier W, Dupont A, Hornef M, Gutsmann T, Mauss K, Weindl G, Brandenburg K.

Adv Exp Med Biol. 2019;1117:111-129. doi: 10.1007/978-981-13-3588-4_8.


Crowdsourcing triggers rapid, reliable earthquake locations.

Steed RJ, Fuenzalida A, Bossu R, Bondár I, Heinloo A, Dupont A, Saul J, Strollo A.

Sci Adv. 2019 Apr 3;5(4):eaau9824. doi: 10.1126/sciadv.aau9824. eCollection 2019 Apr.


Impact of health technology assessment and managed entry schemes on reimbursement decisions of centrally authorised medicinal products in Belgium.

Van Wilder P, Pirson M, Dupont A.

Eur J Clin Pharmacol. 2019 Jul;75(7):895-900. doi: 10.1007/s00228-019-02665-6. Epub 2019 Mar 15.


Variability in functional outcome and treatment practices by treatment center after out-of-hospital cardiac arrest: analysis of International Cardiac Arrest Registry.

May TL, Lary CW, Riker RR, Friberg H, Patel N, Søreide E, McPherson JA, Undén J, Hand R, Sunde K, Stammet P, Rubertsson S, Belohlvaek J, Dupont A, Hirsch KG, Valsson F, Kern K, Sadaka F, Israelsson J, Dankiewicz J, Nielsen N, Seder DB, Agarwal S.

Intensive Care Med. 2019 May;45(5):637-646. doi: 10.1007/s00134-019-05580-7. Epub 2019 Mar 8.


von Willebrand Factor and Management of Heart Valve Disease: JACC Review Topic of the Week.

Van Belle E, Vincent F, Rauch A, Casari C, Jeanpierre E, Loobuyck V, Rosa M, Delhaye C, Spillemaeker H, Paris C, Debry N, Verdier B, Vincentelli A, Dupont A, Lenting PJ, Susen S.

J Am Coll Cardiol. 2019 Mar 12;73(9):1078-1088. doi: 10.1016/j.jacc.2018.12.045. Review.


Early withdrawal of life support after resuscitation from cardiac arrest is common and may result in additional deaths.

May TL, Ruthazer R, Riker RR, Friberg H, Patel N, Soreide E, Hand R, Stammet P, Dupont A, Hirsch KG, Agarwal S, Wanscher MJ, Dankiewicz J, Nielsen N, Seder DB, Kent DM.

Resuscitation. 2019 Jun;139:308-313. doi: 10.1016/j.resuscitation.2019.02.031. Epub 2019 Mar 2.


Synthetic energy sensor AMPfret deciphers adenylate-dependent AMPK activation mechanism.

Pelosse M, Cottet-Rousselle C, Bidan CM, Dupont A, Gupta K, Berger I, Schlattner U.

Nat Commun. 2019 Mar 4;10(1):1038. doi: 10.1038/s41467-019-08938-z.


Relevance of platelet desialylation and thrombocytopenia in type 2B von Willebrand disease: preclinical and clinical evidence.

Dupont A, Soukaseum C, Cheptou M, Adam F, Nipoti T, Lourenco-Rodrigues MD, Legendre P, Proulle V, Rauch A, Kawecki C, Bryckaert M, Rosa JP, Paris C, Ternisien C, Boisseau P, Goudemand J, Borgel D, Lasne D, Maurice P, Lenting PJ, Denis CV, Susen S, Kauskot A.

Haematologica. 2019 Feb 28. pii: haematol.2018.206250. doi: 10.3324/haematol.2018.206250. [Epub ahead of print]


The Significance of So-Called Equivocal Immunohistochemical Staining for Cytomegalovirus in Colorectal Biopsies.

Ambelil M, Saulino DM, Ertan A, DuPont AW, Younes M.

Arch Pathol Lab Med. 2019 Jan 31. doi: 10.5858/arpa.2018-0235-OA. [Epub ahead of print]


[Staphylococcal toxic shock syndrome should be considered in the event of diffuse erythema with fever and shock].

Dugourd PM, Dupont A, Hubiche T, Chiaverini C, Alkhalifa A, Roudiere L, Tristan A, Gustave CA, Del Giudice P.

Ann Dermatol Venereol. 2019 Apr;146(4):287-291. doi: 10.1016/j.annder.2018.12.002. Epub 2019 Jan 26. French.


Femtosecond laser inscription of depressed cladding single-mode mid-infrared waveguides in sapphire.

Bérubé JP, Lapointe J, Dupont A, Bernier M, Vallée R.

Opt Lett. 2019 Jan 1;44(1):37-40. doi: 10.1364/OL.44.000037.


Health Economic Evaluations of Digital Health Interventions for Secondary Prevention in Stroke Patients: A Systematic Review.

Valenzuela Espinoza A, Steurbaut S, Dupont A, Cornu P, van Hooff RJ, Brouns R, Putman K.

Cerebrovasc Dis Extra. 2019 Jan 7;9(1):1-8. doi: 10.1159/000496107. [Epub ahead of print]


Long-Term Outcome and Prognostic Factors of Complications in Thromboangiitis Obliterans (Buerger's Disease): A Multicenter Study of 224 Patients.

Le Joncour A, Soudet S, Dupont A, Espitia O, Koskas F, Cluzel P, Hatron PY, Emmerich J, Cacoub P, Resche-Rigon M, Lambert M, Saadoun D; French Buerger's Network.

J Am Heart Assoc. 2018 Dec 4;7(23):e010677. doi: 10.1161/JAHA.118.010677.


Pancreatic Acinar Metaplasia in Distal Esophageal Biopsies Is Associated With Chronic Nonsteroidal Anti-inflammatory Drug Use.

Al Salihi S, Jaitly V, Saulino DM, DuPont AW, Ertan A, Everett JM, Younes M.

Arch Pathol Lab Med. 2019 Apr;143(4):510-512. doi: 10.5858/arpa.2018-0152-OA. Epub 2018 Dec 10.


Appropriateness of DOAC Prescribing Before and During Hospital Admission and Analysis of Determinants for Inappropriate Prescribing.

Moudallel S, Steurbaut S, Cornu P, Dupont A.

Front Pharmacol. 2018 Oct 30;9:1220. doi: 10.3389/fphar.2018.01220. eCollection 2018.


Wide clinical spectrum in ALG8-CDG: clues from molecular findings suggest an explanation for a milder phenotype in the first-described patient.

Vuillaumier-Barrot S, Schiff M, Mattioli F, Schaefer E, Dupont A, Dancourt J, Dupré T, Couvineau A, de Baulny HO, de Lonlay P, Seta N, Moore S, Chantret I.

Pediatr Res. 2019 Feb;85(3):384-389. doi: 10.1038/s41390-018-0231-5. Epub 2018 Nov 12.


Safety and preliminary efficacy of orally administered lyophilized fecal microbiota product compared with frozen product given by enema for recurrent Clostridium difficile infection: A randomized clinical trial.

Jiang ZD, Jenq RR, Ajami NJ, Petrosino JF, Alexander AA, Ke S, Iqbal T, DuPont AW, Muldrew K, Shi Y, Peterson C, Do KA, DuPont HL.

PLoS One. 2018 Nov 2;13(11):e0205064. doi: 10.1371/journal.pone.0205064. eCollection 2018.


Accurate molar masses of cellulose for the determination of degradation rates in complex paper samples.

Dupont AL, Réau D, Bégin P, Paris-Lacombe S, Tétreault J, Mortha G.

Carbohydr Polym. 2018 Dec 15;202:172-185. doi: 10.1016/j.carbpol.2018.08.134. Epub 2018 Aug 31.


Clinical Decision Support Systems for Drug Allergy Checking: Systematic Review.

Légat L, Van Laere S, Nyssen M, Steurbaut S, Dupont AG, Cornu P.

J Med Internet Res. 2018 Sep 7;20(9):e258. doi: 10.2196/jmir.8206. Review.


Real-Time Monitoring of von Willebrand Factor in the Catheterization Laboratory: The Seatbelt of Mini-Invasive Transcatheter Aortic Valve Replacement?

Vincent F, Rauch A, Spillemaeker H, Vincentelli A, Paris C, Rosa M, Dupont A, Delhaye C, Verdier B, Robin E, Lenting PJ, Susen S, Van Belle E.

JACC Cardiovasc Interv. 2018 Sep 10;11(17):1775-1778. doi: 10.1016/j.jcin.2018.05.047. Review.


Staphylococcus aureus Extracellular Vesicles Elicit an Immunostimulatory Response in vivo on the Murine Mammary Gland.

Tartaglia NR, Breyne K, Meyer E, Cauty C, Jardin J, Chrétien D, Dupont A, Demeyere K, Berkova N, Azevedo V, Guédon E, Le Loir Y.

Front Cell Infect Microbiol. 2018 Aug 22;8:277. doi: 10.3389/fcimb.2018.00277. eCollection 2018.


Publisher Correction: Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition.

Fulde M, Sommer F, Chassaing B, van Vorst K, Dupont A, Hensel M, Basic M, Klopfleisch R, Rosenstiel P, Bleich A, Bäckhed F, Gewirtz AT, Hornef MW.

Nature. 2018 Nov;563(7731):E25. doi: 10.1038/s41586-018-0507-2.


Surgery and risk of Guillain-Barré syndrome: A French nationwide epidemiologic study.

Rudant J, Dupont A, Mikaeloff Y, Bolgert F, Coste J, Weill A.

Neurology. 2018 Sep 25;91(13):e1220-e1227. doi: 10.1212/WNL.0000000000006246. Epub 2018 Aug 24.


Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition.

Fulde M, Sommer F, Chassaing B, van Vorst K, Dupont A, Hensel M, Basic M, Klopfleisch R, Rosenstiel P, Bleich A, Bäckhed F, Gewirtz AT, Hornef MW.

Nature. 2018 Aug;560(7719):489-493. doi: 10.1038/s41586-018-0395-5. Epub 2018 Aug 8. Erratum in: Nature. 2018 Nov;563(7731):E25.


Evolution of platelet functions in cirrhotic patients undergoing liver transplantation: A prospective exploration over a month.

Eyraud D, Suner L, Dupont A, Bachelot-Loza C, Smadja DM, Helley D, Bertil S, Gostian O, Szymezak J, Loncar Y, Puybasset L, Lebray P, Vezinet C, Vaillant JC, Granger B, Gaussem P.

PLoS One. 2018 Aug 2;13(8):e0200364. doi: 10.1371/journal.pone.0200364. eCollection 2018.


Effect of In-Bed Leg Cycling and Electrical Stimulation of the Quadriceps on Global Muscle Strength in Critically Ill Adults: A Randomized Clinical Trial.

Fossat G, Baudin F, Courtes L, Bobet S, Dupont A, Bretagnol A, Benzekri-Lefèvre D, Kamel T, Muller G, Bercault N, Barbier F, Runge I, Nay MA, Skarzynski M, Mathonnet A, Boulain T.

JAMA. 2018 Jul 24;320(4):368-378. doi: 10.1001/jama.2018.9592.


Antioxidant defense capacity of ovarian tissue after vitrification in a metal closed system.

Massignam ET, Ferreira M, Sanguinet E, Dupont Á, Klamt F, Frantz N, Bos-Mikich A.

JBRA Assist Reprod. 2018 Sep 1;22(3):199-204. doi: 10.5935/1518-0557.20180044.


The Place of PET to Assess New Therapeutic Effectiveness in Neurodegenerative Diseases.

Dupont AC, Largeau B, Guilloteau D, Santiago Ribeiro MJ, Arlicot N.

Contrast Media Mol Imaging. 2018 May 17;2018:7043578. doi: 10.1155/2018/7043578. eCollection 2018. Review.


Arterial Pulsatility and Circulating von Willebrand Factor in Patients on Mechanical Circulatory Support.

Vincent F, Rauch A, Loobuyck V, Robin E, Nix C, Vincentelli A, Smadja DM, Leprince P, Amour J, Lemesle G, Spillemaeker H, Debry N, Latremouille C, Jansen P, Capel A, Moussa M, Rousse N, Schurtz G, Delhaye C, Paris C, Jeanpierre E, Dupont A, Corseaux D, Rosa M, Sottejeau Y, Barth S, Mourran C, Gomane V, Coisne A, Richardson M, Caron C, Preda C, Ung A, Carpentier A, Hubert T, Denis C, Staels B, Lenting PJ, Van Belle E, Susen S.

J Am Coll Cardiol. 2018 May 15;71(19):2106-2118. doi: 10.1016/j.jacc.2018.02.075.


GABAergic Signaling Mediates Central Cardiovascular Angiotensin II Type 2 Receptor Effects.

Légat L, Smolders I, Dupont AG.

Trends Endocrinol Metab. 2018 Sep;29(9):605-606. doi: 10.1016/j.tem.2018.04.005. Epub 2018 May 5. No abstract available.


Performance Evaluation of a Dedicated Preclinical PET/CT System for the Assessment of Mineralization Process in a Mouse Model of Atherosclerosis.

Rucher G, Cameliere L, Fendri J, Abbas A, Dupont K, Kamel S, Delcroix N, Dupont A, Berger L, Manrique A.

Mol Imaging Biol. 2018 Dec;20(6):984-992. doi: 10.1007/s11307-018-1202-2.


Improving and monitoring air quality.

DuPont A.

Environ Sci Pollut Res Int. 2018 May;25(15):15253-15263. doi: 10.1007/s11356-018-1897-2. Epub 2018 Apr 17. Review.


Niemann-Pick C2 protein regulates sterol transport between plasma membrane and late endosomes in human fibroblasts.

Berzina Z, Solanko LM, Mehadi AS, Jensen MLV, Lund FW, Modzel M, Szomek M, Solanko KA, Dupont A, Nielsen GK, Heegaard CW, Ejsing CS, Wüstner D.

Chem Phys Lipids. 2018 Jul;213:48-61. doi: 10.1016/j.chemphyslip.2018.03.006. Epub 2018 Mar 23.


Minimal SPI1-T3SS effector requirement for Salmonella enterocyte invasion and intracellular proliferation in vivo.

Zhang K, Riba A, Nietschke M, Torow N, Repnik U, Pütz A, Fulde M, Dupont A, Hensel M, Hornef M.

PLoS Pathog. 2018 Mar 9;14(3):e1006925. doi: 10.1371/journal.ppat.1006925. eCollection 2018 Mar.


Live-cell imaging of new polyene sterols for improved analysis of intracellular cholesterol transport.

Modzel M, Solanko KA, Szomek M, Hansen SK, Dupont A, Nåbo LJ, Kongsted J, Wüstner D.

J Microsc. 2018 Jul;271(1):36-48. doi: 10.1111/jmi.12691. Epub 2018 Mar 8.


Magneto-active substrates for local mechanical stimulation of living cells.

Bidan CM, Fratzl M, Coullomb A, Moreau P, Lombard AH, Wang I, Balland M, Boudou T, Dempsey NM, Devillers T, Dupont A.

Sci Rep. 2018 Jan 23;8(1):1464. doi: 10.1038/s41598-018-19804-1.


July 14, 2016, Terror Attack in Nice, France.

Solla F, Carboni J, Bréaud J, Babe P, Brézac G, Chivoret N, Dupont A, Fernandez A.

Acad Pediatr. 2018 May - Jun;18(4):361-363. doi: 10.1016/j.acap.2018.01.004. Epub 2018 Jan 10.


Severe casualties from Bastille Day Attack in Nice, France.

Solla F, Carboni J, Fernandez A, Dupont A, Chivoret N, Brézac G, Rampal V, Bréaud J.

Eur J Trauma Emerg Surg. 2018 Jan 9. doi: 10.1007/s00068-018-0901-3. [Epub ahead of print]


Time Gain Needed for In-Ambulance Telemedicine: Cost-Utility Model.

Valenzuela Espinoza A, Devos S, van Hooff RJ, Fobelets M, Dupont A, Moens M, Hubloue I, Lauwaert D, Cornu P, Brouns R, Putman K.

JMIR Mhealth Uhealth. 2017 Nov 24;5(11):e175. doi: 10.2196/mhealth.8288.


TSPO PET Imaging: From Microglial Activation to Peripheral Sterile Inflammatory Diseases?

Largeau B, Dupont AC, Guilloteau D, Santiago-Ribeiro MJ, Arlicot N.

Contrast Media Mol Imaging. 2017 Sep 25;2017:6592139. doi: 10.1155/2017/6592139. eCollection 2017. Review.


In vivo analysis of mucosal lipids reveals histological disease activity in ulcerative colitis using endoscope-coupled Raman spectroscopy.

Ding H, Dupont AW, Singhal S, Scott LD, Guha S, Younes M, Bi X.

Biomed Opt Express. 2017 Jun 23;8(7):3426-3439. doi: 10.1364/BOE.8.003426. eCollection 2017 Jul 1.


Hypotensive Response to Angiotensin II Type 2 Receptor Stimulation in the Rostral Ventrolateral Medulla Requires Functional GABA-A Receptors.

Légat L, Brouwers S, Smolders IJ, Dupont AG.

Front Neurosci. 2017 Jun 19;11:346. doi: 10.3389/fnins.2017.00346. eCollection 2017.


Estimation of the added value of 99mTc-HMPAO labelled white blood cells scintigraphy for the diagnosis of infectious foci.

Malherbe C, Dupont AC, Maia S, Venel Y, Erra B, Santiago-Ribeiro MJ, Arlicot N.

Q J Nucl Med Mol Imaging. 2017 May 3. doi: 10.23736/S1824-4785.17.02964-8. [Epub ahead of print]


Development of Reliable and Validated Tools to Evaluate Technical Resuscitation Skills in a Pediatric Simulation Setting: Resuscitation and Emergency Simulation Checklist for Assessment in Pediatrics.

Faudeux C, Tran A, Dupont A, Desmontils J, Montaudié I, Bréaud J, Braun M, Fournier JP, Bérard E, Berlengi N, Schweitzer C, Haas H, Caci H, Gatin A, Giovannini-Chami L.

J Pediatr. 2017 Sep;188:252-257.e6. doi: 10.1016/j.jpeds.2017.03.055. Epub 2017 Apr 26.


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