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Items: 26


Comprehensive molecular landscape in patients older than 80 years old diagnosed with acute myeloid leukemia: A study of the French Hauts-de-France AML observatory.

Renaud L, Nibourel O, Marceau-Renaut A, Gruson B, Cambier N, Lionne-Huyghe P, Choufi B, Rodriguez C, Frimat C, Plantier I, Stalnikiewicz L, Bemba M, Berthon C, Marolleau JP, Quesnel B, Preudhomme C, Duployez N.

Am J Hematol. 2018 Oct 25. doi: 10.1002/ajh.25328. [Epub ahead of print] No abstract available.


A 17-gene-expression profile to improve prognosis prediction in childhood acute myeloid leukemia.

Duployez N, Preudhomme C, Cheok M.

Oncotarget. 2018 Sep 21;9(74):33869-33870. doi: 10.18632/oncotarget.26116. eCollection 2018 Sep 21. No abstract available.


Acute Myeloid Leukemia: The Good, the Bad, and the Ugly.

Kuykendall A, Duployez N, Boissel N, Lancet JE, Welch JS.

Am Soc Clin Oncol Educ Book. 2018 May 23;(38):555-573. doi: 10.1200/EDBK_199519. Review.


The stem cell-associated gene expression signature allows risk stratification in pediatric acute myeloid leukemia.

Duployez N, Marceau-Renaut A, Villenet C, Petit A, Rousseau A, Ng SWK, Paquet A, Gonzales F, Barthélémy A, Leprêtre F, Pottier N, Nelken B, Michel G, Baruchel A, Bertrand Y, Leverger G, Lapillonne H, Figeac M, Dick JE, Wang JCY, Preudhomme C, Cheok M.

Leukemia. 2018 Aug 8. doi: 10.1038/s41375-018-0227-5. [Epub ahead of print]


Polycomb repressive complex 2 haploinsufficiency identifies a high-risk subgroup of pediatric acute myeloid leukemia.

Bond J, Labis E, Marceau-Renaut A, Duployez N, Labopin M, Hypolite G, Michel G, Ducassou S, Boutroux H, Nelken B, Bertrand Y, Baruchel A, Petit A, Asnafi V, Leverger G, Preudhomme C, Macintyre E, Lapillonne H.

Leukemia. 2018 Aug;32(8):1878-1882. doi: 10.1038/s41375-018-0187-9. Epub 2018 Jun 27. No abstract available.


A novel type of NPM1 mutation characterized by multiple internal tandem repeats in a case of cytogenetically normal acute myeloid leukemia.

Duployez N, Chebrek L, Helevaut N, Fournier E, Bemba M, Caillault A, Geffroy S, Preudhomme C.

Haematologica. 2018 Jun 14. pii: haematol.2018.190959. doi: 10.3324/haematol.2018.190959. [Epub ahead of print] No abstract available.


Clonal interference of signaling mutations worsens prognosis in core-binding factor acute myeloid leukemia.

Itzykson R, Duployez N, Fasan A, Decool G, Marceau-Renaut A, Meggendorfer M, Jourdan E, Petit A, Lapillonne H, Micol JB, Cornillet-Lefebvre P, Ifrah N, Leverger G, Dombret H, Boissel N, Haferlach T, Preudhomme C.

Blood. 2018 Jul 12;132(2):187-196. doi: 10.1182/blood-2018-03-837781. Epub 2018 Apr 24.


SNP-array lesions in core binding factor acute myeloid leukemia.

Duployez N, Boudry-Labis E, Roumier C, Boissel N, Petit A, Geffroy S, Helevaut N, Celli-Lebras K, Terré C, Fenneteau O, Cuccuini W, Luquet I, Lapillonne H, Lacombe C, Cornillet P, Ifrah N, Dombret H, Leverger G, Jourdan E, Preudhomme C.

Oncotarget. 2018 Jan 8;9(5):6478-6489. doi: 10.18632/oncotarget.24031. eCollection 2018 Jan 19.


Reactive oxygen species levels control NF-κB activation by low dose deferasirox in erythroid progenitors of low risk myelodysplastic syndromes.

Meunier M, Ancelet S, Lefebvre C, Arnaud J, Garrel C, Pezet M, Wang Y, Faure P, Szymanski G, Duployez N, Preudhomme C, Biard D, Polack B, Cahn JY, Moulis JM, Park S.

Oncotarget. 2017 Nov 6;8(62):105510-105524. doi: 10.18632/oncotarget.22299. eCollection 2017 Dec 1.


Detection of a new heterozygous germline ETV6 mutation in a case with hyperdiploid acute lymphoblastic leukemia.

Duployez N, Abou Chahla W, Lejeune S, Marceau-Renaut A, Letizia G, Boyer T, Geffroy S, Peyrouze P, Grardel N, Nelken B, Michel G, Bertrand Y, Preudhomme C.

Eur J Haematol. 2018 Jan;100(1):104-107. doi: 10.1111/ejh.12981. Epub 2017 Nov 9. Review.


Lineage switch from B acute lymphoblastic leukemia to acute monocytic leukemia with persistent t(4;11)(q21;q23) and cytogenetic evolution under CD19-targeted therapy.

Balducci E, Nivaggioni V, Boudjarane J, Bouriche L, Rahal I, Bernot D, Alazard E, Duployez N, Grardel N, Arnoux I, Lafage-Pochitaloff M, Michel G, Nadel B, Loosveld M.

Ann Hematol. 2017 Sep;96(9):1579-1581. doi: 10.1007/s00277-017-3050-6. Epub 2017 Jun 20. No abstract available.


ASXL2 is essential for haematopoiesis and acts as a haploinsufficient tumour suppressor in leukemia.

Micol JB, Pastore A, Inoue D, Duployez N, Kim E, Lee SC, Durham BH, Chung YR, Cho H, Zhang XJ, Yoshimi A, Krivtsov A, Koche R, Solary E, Sinha A, Preudhomme C, Abdel-Wahab O.

Nat Commun. 2017 May 18;8:15429. doi: 10.1038/ncomms15429.


High-throughput sequencing in acute lymphoblastic leukemia: Follow-up of minimal residual disease and emergence of new clones.

Salson M, Giraud M, Caillault A, Grardel N, Duployez N, Ferret Y, Duez M, Herbert R, Rocher T, Sebda S, Quief S, Villenet C, Figeac M, Preudhomme C.

Leuk Res. 2017 Feb;53:1-7. doi: 10.1016/j.leukres.2016.11.009. Epub 2016 Nov 21.


Myelodysplastic syndromes and acute leukemia with genetic predispositions: a new challenge for hematologists.

Duployez N, Lejeune S, Renneville A, Preudhomme C.

Expert Rev Hematol. 2016 Dec;9(12):1189-1202. Epub 2016 Nov 21. Review.


Comprehensive mutational profiling of core binding factor acute myeloid leukemia.

Duployez N, Marceau-Renaut A, Boissel N, Petit A, Bucci M, Geffroy S, Lapillonne H, Renneville A, Ragu C, Figeac M, Celli-Lebras K, Lacombe C, Micol JB, Abdel-Wahab O, Cornillet P, Ifrah N, Dombret H, Leverger G, Jourdan E, Preudhomme C.

Blood. 2016 May 19;127(20):2451-9. doi: 10.1182/blood-2015-12-688705. Epub 2016 Mar 15.


Acquisition of genomic events leading to lymphoblastic transformation in a rare case of myeloproliferative neoplasm with BCR-JAK2 fusion transcript.

Duployez N, Nibourel O, Ducourneau B, Grardel N, Boyer T, Bories C, Darre S, Coiteux V, Berthon C, Preudhomme C, Roche-Lestienne C.

Eur J Haematol. 2016 Oct;97(4):399-402. doi: 10.1111/ejh.12752. Epub 2016 Mar 26.


Multi-loci diagnosis of acute lymphoblastic leukaemia with high-throughput sequencing and bioinformatics analysis.

Ferret Y, Caillault A, Sebda S, Duez M, Grardel N, Duployez N, Villenet C, Figeac M, Preudhomme C, Salson M, Giraud M.

Br J Haematol. 2016 May;173(3):413-20. doi: 10.1111/bjh.13981. Epub 2016 Feb 21.


NUP214-ABL1 fusion defines a rare subtype of B-cell precursor acute lymphoblastic leukemia that could benefit from tyrosine kinase inhibitors.

Duployez N, Grzych G, Ducourneau B, Alarcon Fuentes M, Grardel N, Boyer T, Abou Chahla W, Bruno B, Nelken B, Clappier E, Preudhomme C.

Haematologica. 2016 Apr;101(4):e133-4. doi: 10.3324/haematol.2015.136499. Epub 2015 Dec 17. No abstract available.


Diagnosis of intrachromosomal amplification of chromosome 21 (iAMP21) by molecular cytogenetics in pediatric acute lymphoblastic leukemia.

Duployez N, Boudry-Labis E, Decool G, Grzych G, Grardel N, Abou Chahla W, Preudhomme C, Roche-Lestienne C.

Clin Case Rep. 2015 Oct;3(10):814-6. doi: 10.1002/ccr3.357. Epub 2015 Aug 26.


Somatic mutations associated with leukemic progression of familial platelet disorder with predisposition to acute myeloid leukemia.

Antony-Debré I, Duployez N, Bucci M, Geffroy S, Micol JB, Renneville A, Boissel N, Dhédin N, Réa D, Nelken B, Berthon C, Leblanc T, Mozziconacci MJ, Favier R, Heller PG, Abdel-Wahab O, Raslova H, Latger-Cannard V, Preudhomme C.

Leukemia. 2016 Apr;30(4):999-1002. doi: 10.1038/leu.2015.236. Epub 2015 Aug 28. No abstract available.


Incidence of ATRX mutations in myelodysplastic syndromes, the value of microcytosis.

Herbaux C, Duployez N, Badens C, Poret N, Gardin C, Decamp M, Eclache V, Daliphard S, Murati A, Cony-Makhoul P, Cheze S, Beve B, Lacoste C, Prebet T, Hunault-Berger M, Maloisel F, Renneville A, Figeac M, Stamatoullas-Bastard A, Bastard C, Fenaux P, Preudhomme C, Rose C; GFM (Groupe Francophone des Myelodysplasies).

Am J Hematol. 2015 Aug;90(8):737-8. doi: 10.1002/ajh.24073.


Unlike ASXL1 and ASXL2 mutations, ASXL3 mutations are rare events in acute myeloid leukemia with t(8;21).

Duployez N, Micol JB, Boissel N, Petit A, Geffroy S, Bucci M, Lapillonne H, Renneville A, Leverger G, Ifrah N, Dombret H, Abdel-Wahab O, Jourdan E, Preudhomme C.

Leuk Lymphoma. 2016;57(1):199-200. doi: 10.3109/10428194.2015.1037754. Epub 2015 May 15. No abstract available.


Prognosis and monitoring of core-binding factor acute myeloid leukemia: current and emerging factors.

Duployez N, Willekens C, Marceau-Renaut A, Boudry-Labis E, Preudhomme C.

Expert Rev Hematol. 2015 Feb;8(1):43-56. doi: 10.1586/17474086.2014.976551. Epub 2014 Oct 28. Review.


Frequent ASXL2 mutations in acute myeloid leukemia patients with t(8;21)/RUNX1-RUNX1T1 chromosomal translocations.

Micol JB, Duployez N, Boissel N, Petit A, Geffroy S, Nibourel O, Lacombe C, Lapillonne H, Etancelin P, Figeac M, Renneville A, Castaigne S, Leverger G, Ifrah N, Dombret H, Preudhomme C, Abdel-Wahab O, Jourdan E.

Blood. 2014 Aug 28;124(9):1445-9. doi: 10.1182/blood-2014-04-571018. Epub 2014 Jun 27.


Minimal residual disease monitoring in t(8;21) acute myeloid leukemia based on RUNX1-RUNX1T1 fusion quantification on genomic DNA.

Duployez N, Nibourel O, Marceau-Renaut A, Willekens C, Helevaut N, Caillault A, Villenet C, Celli-Lebras K, Boissel N, Jourdan E, Dombret H, Figeac M, Preudhomme C, Renneville A.

Am J Hematol. 2014 Jun;89(6):610-5. doi: 10.1002/ajh.23696. Epub 2014 Mar 8.


Mixed phenotype acute leukaemia with Burkitt-like cells and positive peroxidase cytochemistry.

Duployez N, Debarri H, Fouquet G.

Br J Haematol. 2013 Oct;163(2):148. doi: 10.1111/bjh.12514. Epub 2013 Aug 9. No abstract available.


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