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Items: 32

1.

Expression of AXL receptor tyrosine kinase relates to monocyte dysfunction and severity of cirrhosis.

Brenig R, Pop OT, Triantafyllou E, Geng A, Singanayagam A, Perez-Shibayama C, Besse L, Cupovic J, Künzler P, Boldanova T, Brand S, Semela D, Duong FH, Weston CJ, Ludewig B, Heim MH, Wendon J, Antoniades CG, Bernsmeier C.

Life Sci Alliance. 2019 Dec 10;3(1). pii: e201900465. doi: 10.26508/lsa.201900465. Print 2020 Jan.

2.

HCV-Induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic Response.

Hamdane N, Jühling F, Crouchet E, El Saghire H, Thumann C, Oudot MA, Bandiera S, Saviano A, Ponsolles C, Roca Suarez AA, Li S, Fujiwara N, Ono A, Davidson I, Bardeesy N, Schmidl C, Bock C, Schuster C, Lupberger J, Habersetzer F, Doffoël M, Piardi T, Sommacale D, Imamura M, Uchida T, Ohdan H, Aikata H, Chayama K, Boldanova T, Pessaux P, Fuchs BC, Hoshida Y, Zeisel MB, Duong FHT, Baumert TF.

Gastroenterology. 2019 Jun;156(8):2313-2329.e7. doi: 10.1053/j.gastro.2019.02.038. Epub 2019 Mar 2.

3.

SOCS1 is an inducible negative regulator of interferon λ (IFN-λ)-induced gene expression in vivo.

Blumer T, Coto-Llerena M, Duong FHT, Heim MH.

J Biol Chem. 2017 Oct 27;292(43):17928-17938. doi: 10.1074/jbc.M117.788877. Epub 2017 Sep 12.

4.

miR-135a-5p-mediated downregulation of protein tyrosine phosphatase receptor delta is a candidate driver of HCV-associated hepatocarcinogenesis.

Van Renne N, Roca Suarez AA, Duong FHT, Gondeau C, Calabrese D, Fontaine N, Ababsa A, Bandiera S, Croonenborghs T, Pochet N, De Blasi V, Pessaux P, Piardi T, Sommacale D, Ono A, Chayama K, Fujita M, Nakagawa H, Hoshida Y, Zeisel MB, Heim MH, Baumert TF, Lupberger J.

Gut. 2018 May;67(5):953-962. doi: 10.1136/gutjnl-2016-312270. Epub 2017 Feb 3.

5.

Hepatic Notch1 deletion predisposes to diabetes and steatosis via glucose-6-phosphatase and perilipin-5 upregulation.

Bernsmeier C, Dill MT, Provenzano A, Makowska Z, Krol I, Muscogiuri G, Semela D, Tornillo L, Marra F, Heim MH, Duong FH.

Lab Invest. 2016 Sep;96(9):972-80. doi: 10.1038/labinvest.2016.75. Epub 2016 Jul 18.

6.

Corrigendum: reduced IFNλ4 activity is associated with improved HCV clearance and reduced expression of interferon-stimulated genes.

Terczyńska-Dyla E, Bibert S, Duong FHT, Krol I, Jørgensen S, Collinet E, Kutalik Z, Aubert V, Cerny A, Kaiser L, Malinverni R, Mangia A, Moradpour D, Müllhaupt B, Negro F, Santoro R, Semela D, Semmo N; Swiss Hepatitis C Cohort Study Group, Heim MH, Bochud PY, Hartmann R.

Nat Commun. 2015 Jun 29;6:7280. doi: 10.1038/ncomms8280. No abstract available.

7.

Clearance of persistent hepatitis C virus infection in humanized mice using a claudin-1-targeting monoclonal antibody.

Mailly L, Xiao F, Lupberger J, Wilson GK, Aubert P, Duong FHT, Calabrese D, Leboeuf C, Fofana I, Thumann C, Bandiera S, Lütgehetmann M, Volz T, Davis C, Harris HJ, Mee CJ, Girardi E, Chane-Woon-Ming B, Ericsson M, Fletcher N, Bartenschlager R, Pessaux P, Vercauteren K, Meuleman P, Villa P, Kaderali L, Pfeffer S, Heim MH, Neunlist M, Zeisel MB, Dandri M, McKeating JA, Robinet E, Baumert TF.

Nat Biotechnol. 2015 May;33(5):549-554. doi: 10.1038/nbt.3179. Epub 2015 Mar 23.

8.

Reduced IFNλ4 activity is associated with improved HCV clearance and reduced expression of interferon-stimulated genes.

Terczyńska-Dyla E, Bibert S, Duong FH, Krol I, Jørgensen S, Collinet E, Kutalik Z, Aubert V, Cerny A, Kaiser L, Malinverni R, Mangia A, Moradpour D, Müllhaupt B, Negro F, Santoro R, Semela D, Semmo N; Swiss Hepatitis C Cohort Study Group, Heim MH, Bochud PY, Hartmann R.

Nat Commun. 2014 Dec 23;5:5699. doi: 10.1038/ncomms6699. Erratum in: Nat Commun. 2015;6:7280.

PMID:
25534433
9.

Vitamin D receptor and Jak-STAT signaling crosstalk results in calcitriol-mediated increase of hepatocellular response to IFN-α.

Lange CM, Gouttenoire J, Duong FH, Morikawa K, Heim MH, Moradpour D.

J Immunol. 2014 Jun 15;192(12):6037-44. doi: 10.4049/jimmunol.1302296. Epub 2014 May 12.

10.

IFN-λ receptor 1 expression is induced in chronic hepatitis C and correlates with the IFN-λ3 genotype and with nonresponsiveness to IFN-α therapies.

Duong FH, Trincucci G, Boldanova T, Calabrese D, Campana B, Krol I, Durand SC, Heydmann L, Zeisel MB, Baumert TF, Heim MH.

J Exp Med. 2014 May 5;211(5):857-68. doi: 10.1084/jem.20131557. Epub 2014 Apr 21.

11.

Protein phosphatase 2A promotes hepatocellular carcinogenesis in the diethylnitrosamine mouse model through inhibition of p53.

Duong FH, Dill MT, Matter MS, Makowska Z, Calabrese D, Dietsche T, Ketterer S, Terracciano L, Heim MH.

Carcinogenesis. 2014 Jan;35(1):114-22. doi: 10.1093/carcin/bgt258. Epub 2013 Jul 29.

PMID:
23901063
12.

IL28B expression depends on a novel TT/-G polymorphism which improves HCV clearance prediction.

Bibert S, Roger T, Calandra T, Bochud M, Cerny A, Semmo N, Duong FH, Gerlach T, Malinverni R, Moradpour D, Negro F, Müllhaupt B, Bochud PY; Swiss Hepatitis C Cohort Study.

J Exp Med. 2013 Jun 3;210(6):1109-16. doi: 10.1084/jem.20130012. Epub 2013 May 27.

13.

Epidermal growth factor receptor signaling impairs the antiviral activity of interferon-alpha.

Lupberger J, Duong FH, Fofana I, Zona L, Xiao F, Thumann C, Durand SC, Pessaux P, Zeisel MB, Heim MH, Baumert TF.

Hepatology. 2013 Oct;58(4):1225-35. doi: 10.1002/hep.26404. Epub 2013 Sep 5.

PMID:
23519785
14.

HRas signal transduction promotes hepatitis C virus cell entry by triggering assembly of the host tetraspanin receptor complex.

Zona L, Lupberger J, Sidahmed-Adrar N, Thumann C, Harris HJ, Barnes A, Florentin J, Tawar RG, Xiao F, Turek M, Durand SC, Duong FH, Heim MH, Cosset FL, Hirsch I, Samuel D, Brino L, Zeisel MB, Le Naour F, McKeating JA, Baumert TF.

Cell Host Microbe. 2013 Mar 13;13(3):302-13. doi: 10.1016/j.chom.2013.02.006.

15.

Sequential induction of type I and II interferons mediates a long-lasting gene induction in the liver in response to a novel toll-like receptor 9 agonist.

Makowska Z, Blumer T, Duong FH, La Monica N, Kandimalla ER, Heim MH.

J Hepatol. 2013 Apr;58(4):743-9. doi: 10.1016/j.jhep.2012.11.038. Epub 2012 Dec 1.

PMID:
23207140
16.

Interferon-γ-stimulated genes, but not USP18, are expressed in livers of patients with acute hepatitis C.

Dill MT, Makowska Z, Duong FHT, Merkofer F, Filipowicz M, Baumert TF, Tornillo L, Terracciano L, Heim MH.

Gastroenterology. 2012 Sep;143(3):777-786.e6. doi: 10.1053/j.gastro.2012.05.044. Epub 2012 Jun 4.

PMID:
22677194
17.

Interferon-β and interferon-λ signaling is not affected by interferon-induced refractoriness to interferon-α in vivo.

Makowska Z, Duong FH, Trincucci G, Tough DF, Heim MH.

Hepatology. 2011 Apr;53(4):1154-63. doi: 10.1002/hep.24189.

PMID:
21480323
18.

Interferon-induced gene expression is a stronger predictor of treatment response than IL28B genotype in patients with hepatitis C.

Dill MT, Duong FH, Vogt JE, Bibert S, Bochud PY, Terracciano L, Papassotiropoulos A, Roth V, Heim MH.

Gastroenterology. 2011 Mar;140(3):1021-31. doi: 10.1053/j.gastro.2010.11.039. Epub 2010 Nov 25.

PMID:
21111740
19.

S-adenosyl-methionine and betaine improve early virological response in chronic hepatitis C patients with previous nonresponse.

Filipowicz M, Bernsmeier C, Terracciano L, Duong FH, Heim MH.

PLoS One. 2010 Nov 8;5(11):e15492. doi: 10.1371/journal.pone.0015492. Erratum in: PLoS One. 2010;5(11). doi: 10.1371/annotation/14d47e6a-400a-429e-a487-6dd375e04632.

20.

Hepatitis C virus-induced up-regulation of protein phosphatase 2A inhibits histone modification and DNA damage repair.

Duong FH, Christen V, Lin S, Heim MH.

Hepatology. 2010 Mar;51(3):741-51. doi: 10.1002/hep.23388.

PMID:
20043320
21.

Alpha interferon induces long-lasting refractoriness of JAK-STAT signaling in the mouse liver through induction of USP18/UBP43.

Sarasin-Filipowicz M, Wang X, Yan M, Duong FH, Poli V, Hilton DJ, Zhang DE, Heim MH.

Mol Cell Biol. 2009 Sep;29(17):4841-51. doi: 10.1128/MCB.00224-09. Epub 2009 Jun 29.

22.

Virus-induced over-expression of protein phosphatase 2A inhibits insulin signalling in chronic hepatitis C.

Bernsmeier C, Duong FH, Christen V, Pugnale P, Negro F, Terracciano L, Heim MH.

J Hepatol. 2008 Sep;49(3):429-40. doi: 10.1016/j.jhep.2008.04.007. Epub 2008 Apr 30.

PMID:
18486982
23.

Interferon signaling and treatment outcome in chronic hepatitis C.

Sarasin-Filipowicz M, Oakeley EJ, Duong FH, Christen V, Terracciano L, Filipowicz W, Heim MH.

Proc Natl Acad Sci U S A. 2008 May 13;105(19):7034-9. doi: 10.1073/pnas.0707882105. Epub 2008 May 8.

24.

Activation of endoplasmic reticulum stress response by hepatitis viruses up-regulates protein phosphatase 2A.

Christen V, Treves S, Duong FH, Heim MH.

Hepatology. 2007 Aug;46(2):558-65.

PMID:
17526027
25.

S-Adenosylmethionine and betaine correct hepatitis C virus induced inhibition of interferon signaling in vitro.

Duong FH, Christen V, Filipowicz M, Heim MH.

Hepatology. 2006 Apr;43(4):796-806.

PMID:
16557551
26.
27.

Xaliproden (SR57746A) induces 5-HT1A receptor-mediated MAP kinase activation in PC12 cells.

Appert-Collin A, Duong FH, Passilly DeGrace P, Bennasroune A, Poindron P, Warter JM, Gies JP.

Int J Immunopathol Pharmacol. 2005 Apr-Jun;18(2):233-44.

PMID:
15888246
28.

MAPK activation via 5-hydroxytryptamine 1A receptor is involved in the neuroprotective effects of xaliproden.

Appert-Collin A, Duong FH, Passilly Degrace P, Warter JM, Poindron P, Gies JP.

Int J Immunopathol Pharmacol. 2005 Jan-Mar;18(1):21-31.

PMID:
15698508
29.

Quantification of neurotrophin mRNA expression in PMN mouse: modulation by xaliproden.

Appert-Collin A, Duong FH, Passilly-Degrace P, Gies JP, Warter JM, Poindron P.

Int J Immunopathol Pharmacol. 2004 May-Aug;17(2):157-64.

PMID:
15171816
30.

Hepatitis C virus inhibits interferon signaling through up-regulation of protein phosphatase 2A.

Duong FH, Filipowicz M, Tripodi M, La Monica N, Heim MH.

Gastroenterology. 2004 Jan;126(1):263-77.

PMID:
14699505
31.

Expression of hepatitis c virus proteins inhibits interferon alpha signaling in the liver of transgenic mice.

Blindenbacher A, Duong FH, Hunziker L, Stutvoet ST, Wang X, Terracciano L, Moradpour D, Blum HE, Alonzi T, Tripodi M, La Monica N, Heim MH.

Gastroenterology. 2003 May;124(5):1465-75.

PMID:
12730885
32.

Effect of the nonpeptide neurotrophic compound SR 57746A on the phenotypic survival of purified mouse motoneurons.

Duong FH, Warter JM, Poindron P, Passilly P.

Br J Pharmacol. 1999 Dec;128(7):1385-92.

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