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Items: 1 to 50 of 100

1.

Mutational analysis of pentabrominated diphenyl-induced hepatocellular tumors in rats and mice, tissue levels of PBDE congeners in rats and mice, and AhR genotyping of Wistar Han rats.

Dunnick JK, Pandiri AR, Merrick BA, Kissling GE, Cunny H, Mutlu E, Waidyanatha S, Sills RC, Hong HL, Ton TV, Maynor T, Rescio L, Phillips SL, Devito MJ, Brix A.

Data Brief. 2018 Oct 28;21:2125-2128. doi: 10.1016/j.dib.2018.10.104. eCollection 2018 Dec.

2.

PBDE-47 and PBDE mixture (DE-71) toxicities and liver transcriptomic changes at PND 22 after in utero/postnatal exposure in the rat.

Dunnick JK, Shockley KR, Pandiri AR, Kissling GE, Gerrish KE, Ton TV, Wilson RE, Brar SS, Brix AE, Waidyanatha S, Mutlu E, Morgan DL.

Arch Toxicol. 2018 Nov;92(11):3415-3433. doi: 10.1007/s00204-018-2292-y. Epub 2018 Sep 5.

PMID:
30206662
3.

Carcinogenic activity of pentabrominated diphenyl ether mixture (DE-71) in rats and mice.

Dunnick JK, Pandiri AR, Merrick BA, Kissling GE, Cunny H, Mutlu E, Waidyanatha S, Sills R, Hong HL, Ton TV, Maynor T, Recio L, Phillips SL, Devito MJ, Brix A.

Toxicol Rep. 2018 May 25;5:615-624. doi: 10.1016/j.toxrep.2018.05.010. eCollection 2018.

4.

DNA Methylation Changes in Tbx3 in a Mouse Model Exposed to Polybrominated Diphenyl Ethers.

Shimbo T, Dunnick JK, Brix A, Mav D, Shah R, Roberts JD, Wade PA.

Int J Toxicol. 2017 May/Jun;36(3):229-238. doi: 10.1177/1091581817706676. Epub 2017 May 3.

5.

Tetrabromobisphenol A activates the hepatic interferon pathway in rats.

Dunnick JK, Morgan DL, Elmore SA, Gerrish K, Pandiri A, Ton TV, Shockley KR, Merrick BA.

Toxicol Lett. 2017 Jan 15;266:32-41. doi: 10.1016/j.toxlet.2016.11.019. Epub 2016 Nov 30.

6.

Hepatic transcriptomic alterations for N,N-dimethyl-p-toluidine (DMPT) and p-toluidine after 5-day exposure in rats.

Dunnick JK, Shockley KR, Morgan DL, Brix A, Travlos GS, Gerrish K, Michael Sanders J, Ton TV, Pandiri AR.

Arch Toxicol. 2017 Apr;91(4):1685-1696. doi: 10.1007/s00204-016-1831-7. Epub 2016 Sep 16.

7.

Molecular Changes in the Nasal Cavity after N, N-dimethyl-p-toluidine Exposure.

Dunnick JK, Merrick BA, Brix A, Morgan DL, Gerrish K, Wang Y, Flake G, Foley J, Shockley KR.

Toxicol Pathol. 2016 Aug;44(6):835-47. doi: 10.1177/0192623316637708. Epub 2016 Apr 20.

8.

Disruption of estrogen homeostasis as a mechanism for uterine toxicity in Wistar Han rats treated with tetrabromobisphenol A.

Sanders JM, Coulter SJ, Knudsen GA, Dunnick JK, Kissling GE, Birnbaum LS.

Toxicol Appl Pharmacol. 2016 May 1;298:31-9. doi: 10.1016/j.taap.2016.03.007. Epub 2016 Mar 15.

9.

Environmental chemical exposure may contribute to uterine cancer development: studies with tetrabromobisphenol A.

Dunnick JK, Sanders JM, Kissling GE, Johnson CL, Boyle MH, Elmore SA.

Toxicol Pathol. 2015 Jun;43(4):464-73. doi: 10.1177/0192623314557335. Epub 2014 Dec 4. Review.

PMID:
25476797
10.

N,N-dimethyl-p-toluidine, a component in dental materials, causes hematologic toxic and carcinogenic responses in rodent model systems.

Dunnick JK, Brix A, Sanders JM, Travlos GS.

Toxicol Pathol. 2014;42(3):603-15. doi: 10.1177/0192623313489604. Epub 2013 Jul 18.

11.

The toxicity and pathology of selected dietary herbal medicines.

Dunnick JK, Nyska A.

Toxicol Pathol. 2013 Feb;41(2):374-86. doi: 10.1177/0192623312466451. Epub 2012 Dec 21. Review.

PMID:
23262639
12.

Toxicology and carcinogenesis study of senna in C3B6.129F1-Trp53 tm1Brd N12 haploinsufficient mice.

Surh I, Brix A, French JE, Collins BJ, Sanders JM, Vallant M, Dunnick JK.

Toxicol Pathol. 2013 Jul;41(5):770-8. doi: 10.1177/0192623312464304. Epub 2012 Nov 2.

13.

Characterization of polybrominated diphenyl ether toxicity in Wistar Han rats and use of liver microarray data for predicting disease susceptibilities.

Dunnick JK, Brix A, Cunny H, Vallant M, Shockley KR.

Toxicol Pathol. 2012;40(1):93-106. doi: 10.1177/0192623311429973.

14.

Toxicokinetics of bis(2-chloroethoxy)methane following intravenous administration and dermal application in male and female F344/N rats and B6C3F1 mice.

Waidyanatha S, Johnson JD, Hong SP, Godfrey-Robinson VD, Graves SW, Cristy T, Dunnick JK, Smith CS.

Toxicol Lett. 2011 Aug 28;205(2):215-26. doi: 10.1016/j.toxlet.2011.06.012. Epub 2011 Jun 17.

PMID:
21708233
15.

Investigating the potential for toxicity from long-term use of the herbal products, goldenseal and milk thistle.

Dunnick JK, Singh B, Nyska A, Peckham J, Kissling GE, Sanders JM.

Toxicol Pathol. 2011 Feb;39(2):398-409. doi: 10.1177/0192623310394211. Epub 2011 Feb 7.

PMID:
21300790
16.

Comparative phenotypic assessment of cardiac pathology, physiology, and gene expression in C3H/HeJ, C57BL/6J, and B6C3F1/J mice.

Auerbach SS, Thomas R, Shah R, Xu H, Vallant MK, Nyska A, Dunnick JK.

Toxicol Pathol. 2010 Oct;38(6):923-42. doi: 10.1177/0192623310382864.

PMID:
21037199
17.

Genetic pathways to colorectal cancer.

Lea IA, Jackson MA, Dunnick JK.

Mutat Res. 2009 Nov 2;670(1-2):96-8. doi: 10.1016/j.mrfmmm.2009.06.011. Epub 2009 Jul 1.

18.

Somatic mutation databases as tools for molecular epidemiology and molecular pathology of cancer: proposed guidelines for improving data collection, distribution, and integration.

Olivier M, Petitjean A, Teague J, Forbes S, Dunnick JK, den Dunnen JT, Langerød A, Wilkinson JM, Vihinen M, Cotton RG, Hainaut P; IARC; EC FP6.

Hum Mutat. 2009 Mar;30(3):275-82. doi: 10.1002/humu.20832.

PMID:
19006239
19.
20.

N-ethyl-N-nitrosourea (ENU)-induced meningiomatosis and meningioma in p16(INK4a)/p19(ARF) tumor suppressor gene-deficient mice.

Morrison JP, Satoh H, Foley J, Horton JL, Dunnick JK, Kissling GE, Malarkey DE.

Toxicol Pathol. 2007 Oct;35(6):780-7.

21.

Genetic pathways and mutation profiles of human cancers: site- and exposure-specific patterns.

Lea IA, Jackson MA, Li X, Bailey S, Peddada SD, Dunnick JK.

Carcinogenesis. 2007 Sep;28(9):1851-8. Epub 2007 Aug 11. Review.

22.

Cardiotoxicity of Ma Huang/caffeine or ephedrine/caffeine in a rodent model system.

Dunnick JK, Kissling G, Gerken DK, Vallant MA, Nyska A.

Toxicol Pathol. 2007 Aug;35(5):657-64.

23.
24.

Frequency of Hprt mutant lymphocytes and micronucleated erythrocytes in p53-haplodeficient mice treated perinatally with AZT and AZT in combination with 3TC.

Dobrovolsky VN, Shaddock JG, Mittelstaedt RA, Bishop ME, Lewis SM, Lee FW, Aidoo A, Leakey JE, Dunnick JK, Heflich RH.

Environ Mol Mutagen. 2007 Apr-May;48(3-4):270-82.

PMID:
17358030
25.

Genetic alterations in cancer knowledge system: analysis of gene mutations in mouse and human liver and lung tumors.

Jackson MA, Lea I, Rashid A, Peddada SD, Dunnick JK.

Toxicol Sci. 2006 Apr;90(2):400-18. Epub 2006 Jan 12.

PMID:
16410370
26.
27.

Acute hemorrhagic myocardial necrosis and sudden death of rats exposed to a combination of ephedrine and caffeine.

Nyska A, Murphy E, Foley JF, Collins BJ, Petranka J, Howden R, Hanlon P, Dunnick JK.

Toxicol Sci. 2005 Feb;83(2):388-96. Epub 2004 Nov 10.

PMID:
15537744
28.

Cardiac damage in rodents after exposure to bis(2-chloroethoxy)methane.

Dunnick JK, Lieuallen W, Moyer C, Orzech D, Nyska A.

Toxicol Pathol. 2004 May-Jun;32(3):309-17.

PMID:
15204972
29.

Predominant K-ras codon 12 G --> A transition in chemically induced lung neoplasms in B6C3F1 mice.

Ton TV, Hong HH, Anna CH, Dunnick JK, Devereux TR, Sills RC, Kim Y.

Toxicol Pathol. 2004 Jan-Feb;32(1):16-21.

PMID:
14713543
30.

Chemical-specific alterations in ras, p53, and beta-catenin genes in hemangiosarcomas from B6C3F1 mice exposed to o-nitrotoluene or riddelliine for 2 years.

Hong HL, Ton TV, Devereux TR, Moomaw C, Clayton N, Chan P, Dunnick JK, Sills RC.

Toxicol Appl Pharmacol. 2003 Sep 15;191(3):227-34.

PMID:
13678655
31.

Carcinogenic potential of o-nitrotoluene and p-nitrotoluene.

Dunnick JK, Burka LT, Mahler J, Sills R.

Toxicology. 2003 Feb 1;183(1-3):221-34.

PMID:
12504353
32.

Chromosome 11 loss from thymic lymphomas induced in heterozygous Trp53 mice by phenolphthalein.

Hulla JE, French JE, Dunnick JK.

Toxicol Sci. 2001 Apr;60(2):264-70.

PMID:
11248138
33.

The use of transgenic animals in cancer testing.

French JE, Spalding JW, Dunnick JK, Tice RR, Furedi-Machacek M, Tennant RW.

Inhal Toxicol. 1999 Jun-Jul;11(6-7):541-4. Review. No abstract available.

PMID:
11202994
34.

Loss of heterozygosity frequency at the Trp53 locus in p53-deficient (+/-) mouse tumors is carcinogen-and tissue-dependent.

French JE, Lacks GD, Trempus C, Dunnick JK, Foley J, Mahler J, Tice RR, Tennant RW.

Carcinogenesis. 2001 Jan;22(1):99-106. Erratum in: Carcinogenesis 2002 Feb;23(2):373.

PMID:
11159747
35.

Chromosome 11 allelotypes reflect a mechanism of chemical carcinogenesis in heterozygous p53-deficient mice.

Hulla JE, French JE, Dunnick JK.

Carcinogenesis. 2001 Jan;22(1):89-98.

PMID:
11159746
36.

Toxicokinetics of phenolphthalein in male and female rats and mice.

Collins BJ, Grizzle TB, Dunnick JK.

Toxicol Sci. 2000 Aug;56(2):271-81.

PMID:
10910984
37.

Measurement of micronucleated erythrocytes and DNA damage during chronic ingestion of phenolphthalein in transgenic female mice heterozygous for the p53 gene.

Tice RR, Furedi-Machacek M, Satterfield D, Udumudi A, Vasquez M, Dunnick JK.

Environ Mol Mutagen. 1998;31(2):113-24.

PMID:
9544189
38.

Regenerative hyperplasia is not required for liver tumor induction in female B6C3F1 mice exposed to trihalomethanes.

Melnick RL, Kohn MC, Dunnick JK, Leininger JR.

Toxicol Appl Pharmacol. 1998 Jan;148(1):137-47.

PMID:
9465273
39.

Carcinogenic activity of the flame retardant, 2,2-bis(bromomethyl)-1,3-propanediol in rodents, and comparison with the carcinogenicity of other NTP brominated chemicals.

Dunnick JK, Heath JE, Farnell DR, Prejean JD, Haseman JK, Elwell MR.

Toxicol Pathol. 1997 Nov-Dec;25(6):541-8.

PMID:
9437797
40.

Phenolphthalein induces thymic lymphomas accompanied by loss of the p53 wild type allele in heterozygous p53-deficient (+/-) mice.

Dunnick JK, Hardisty JF, Herbert RA, Seely JC, Furedi-Machacek EM, Foley JF, Lacks GD, Stasiewicz S, French JE.

Toxicol Pathol. 1997 Nov-Dec;25(6):533-40.

PMID:
9437796
41.
42.

Decreased incidence of spontaneous mammary gland neoplasms in female F344 rats treated with amphetamine, methylphenidate, or codeine.

Dunnick JK, Elwell MR, Haseman JK.

Cancer Lett. 1996 Apr 19;102(1-2):77-83. Erratum in: Cancer Lett 1996 Jul 19;105(1):121-2.

PMID:
8603383
43.

Chemicals associated with decreases in the incidence of mononuclear cell leukemia in the Fischer rat.

Elwell MR, Dunnick JK, Hailey JR, Haseman JK.

Toxicol Pathol. 1996 Mar-Apr;24(2):238-45. Erratum in: Toxicol Pathol 1996 Sep-Oct;24(5):618.

PMID:
8992614
44.

Experimental studies on the long-term effects of methylphenidate hydrochloride.

Dunnick JK, Hailey JR.

Toxicology. 1995 Nov 30;103(2):77-84.

PMID:
8545847
45.

Comparative carcinogenic effects of nickel subsulfide, nickel oxide, or nickel sulfate hexahydrate chronic exposures in the lung.

Dunnick JK, Elwell MR, Radovsky AE, Benson JM, Hahn FF, Nikula KJ, Barr EB, Hobbs CH.

Cancer Res. 1995 Nov 15;55(22):5251-6.

46.

Induction of thymic lymphoma in mice administered the dideoxynucleoside ddC.

Sanders VM, Elwell MR, Heath JE, Collins BJ, Dunnick JK, Rao GN, Prejean D, Lindamood C 3rd, Irwin RD.

Fundam Appl Toxicol. 1995 Sep;27(2):263-9.

PMID:
8529822
47.

Chemically induced mammary gland cancer in the National Toxicology Program's carcinogenesis bioassay.

Dunnick JK, Elwell MR, Huff J, Barrett JC.

Carcinogenesis. 1995 Feb;16(2):173-9. Review.

PMID:
7859345
48.

Trihalomethanes and Other Environmental Factors That Contribute to Colorectal Cancer.

Melnick RL, Dunnick JK, Sandler DP, Elwell MR, Barrett JC.

Environ Health Perspect. 1994 Jun;102(6-7):586-8. No abstract available.

49.

Summary of the National Toxicology Program benzidine dye initiative.

Morgan DL, Dunnick JK, Goehl T, Jokinen MP, Matthews HB, Zeiger E, Mennear JH.

Environ Health Perspect. 1994 Jun;102 Suppl 2:63-78. Review.

50.

Comparative toxicities of o-, m-, and p-nitrotoluene in 13-week feed studies in F344 rats and B6C3F1 mice.

Dunnick JK, Elwell MR, Bucher JR.

Fundam Appl Toxicol. 1994 Apr;22(3):411-21.

PMID:
7519572

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