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Correction: Increased proliferation and altered cell cycle regulation in pancreatic stem cells derived from patients with congenital hyperinsulinism.

Kellaway SG, Mosinska K, Mohamed Z, Ryan A, Richardson S, Newbould M, Banerjee I, Dunne MJ, Cosgrove KE.

PLoS One. 2019 Oct 10;14(10):e0223999. doi: 10.1371/journal.pone.0223999. eCollection 2019.


Unravelling the genetic causes of mosaic islet morphology in congenital hyperinsulinism.

Houghton JAL, Banerjee I, Shaikh G, Jabbar S, Laver TW, Cheesman E, Chinnoy A, Yau D, Salomon Estebanez M, Dunne MJ, Flanagan SE.

J Pathol Clin Res. 2019 Oct 2. doi: 10.1002/cjp2.144. [Epub ahead of print]


Increased proliferation and altered cell cycle regulation in pancreatic stem cells derived from patients with congenital hyperinsulinism.

Kellaway SG, Mosinska K, Mohamed Z, Ryan A, Richardson S, Newbould M, Banerjee I, Dunne MJ, Cosgrove KE.

PLoS One. 2019 Sep 16;14(9):e0222350. doi: 10.1371/journal.pone.0222350. eCollection 2019. Erratum in: PLoS One. 2019 Oct 10;14(10):e0223999.


Central venous catheter-associated thrombosis in children with congenital hyperinsulinism

Yau D, Salomon-Estebanez M, Chinoy A, Grainger J, Craigie RJ, Padidela R, Skae M, Dunne MJ, Murray PG, Banerjee I.

Endocrinol Diabetes Metab Case Rep. 2019 Jul 9;2019(1). doi: 10.1530/EDM-19-0032.


Clinical Diversity in Focal Congenital Hyperinsulinism in Infancy Correlates With Histological Heterogeneity of Islet Cell Lesions.

Craigie RJ, Salomon-Estebanez M, Yau D, Han B, Mal W, Newbould M, Cheesman E, Bitetti S, Mohamed Z, Sajjan R, Padidela R, Skae M, Flanagan S, Ellard S, Cosgrove KE, Banerjee I, Dunne MJ.

Front Endocrinol (Lausanne). 2018 Oct 17;9:619. doi: 10.3389/fendo.2018.00619. eCollection 2018.


Therapies and outcomes of congenital hyperinsulinism-induced hypoglycaemia.

Banerjee I, Salomon-Estebanez M, Shah P, Nicholson J, Cosgrove KE, Dunne MJ.

Diabet Med. 2019 Jan;36(1):9-21. doi: 10.1111/dme.13823. Epub 2018 Oct 8. Review.


Impacts of the Affordable Care Act on Community Health Centers: Characteristics of New Patients and Early Changes in Delivery of Care.

Hatch B, Smith N, McBurnie MA, Quach T, Mayer KH, Dunne MJ, Cottrell E.

J Ambul Care Manage. 2018 Oct/Dec;41(4):250-261. doi: 10.1097/JAC.0000000000000244.


Focal Congenital Hyperinsulinism as a Cause for Sudden Infant Death.

Chinoy A, Banerjee I, Flanagan SE, Ellard S, Han B, Mohamed Z, Dunne MJ, Bitetti S.

Pediatr Dev Pathol. 2019 Jan-Feb;22(1):65-69. doi: 10.1177/1093526618765376. Epub 2018 Mar 20.


Interviews with Patients and Providers on Transgender and Gender Nonconforming Health Data Collection in the Electronic Health Record.

Dunne MJ, Raynor LA, Cottrell EK, Pinnock WJA.

Transgend Health. 2017 Feb 1;2(1):1-7. doi: 10.1089/trgh.2016.0041. eCollection 2017.


Deubiquitinating Enzyme USP9X Suppresses Tumor Growth via LATS Kinase and Core Components of the Hippo Pathway.

Toloczko A, Guo F, Yuen HF, Wen Q, Wood SA, Ong YS, Chan PY, Shaik AA, Gunaratne J, Dunne MJ, Hong W, Chan SW.

Cancer Res. 2017 Sep 15;77(18):4921-4933. doi: 10.1158/0008-5472.CAN-16-3413. Epub 2017 Jul 18.


Atypical Forms of Congenital Hyperinsulinism in Infancy Are Associated With Mosaic Patterns of Immature Islet Cells.

Han B, Mohamed Z, Estebanez MS, Craigie RJ, Newbould M, Cheesman E, Padidela R, Skae M, Johnson M, Flanagan S, Ellard S, Cosgrove KE, Banerjee I, Dunne MJ.

J Clin Endocrinol Metab. 2017 Sep 1;102(9):3261-3267. doi: 10.1210/jc.2017-00158.


Functional and Metabolomic Consequences of KATP Channel Inactivation in Human Islets.

Li C, Ackermann AM, Boodhansingh KE, Bhatti TR, Liu C, Schug J, Doliba N, Han B, Cosgrove KE, Banerjee I, Matschinsky FM, Nissim I, Kaestner KH, Naji A, Adzick NS, Dunne MJ, Stanley CA, De León DD.

Diabetes. 2017 Jul;66(7):1901-1913. doi: 10.2337/db17-0029. Epub 2017 Apr 25.


Extreme caution on the use of sirolimus for the congenital hyperinsulinism in infancy patient.

Banerjee I, De Leon D, Dunne MJ.

Orphanet J Rare Dis. 2017 Apr 14;12(1):70. doi: 10.1186/s13023-017-0621-5.


Conservatively treated Congenital Hyperinsulinism (CHI) due to K-ATP channel gene mutations: reducing severity over time.

Salomon-Estebanez M, Flanagan SE, Ellard S, Rigby L, Bowden L, Mohamed Z, Nicholson J, Skae M, Hall C, Craigie R, Padidela R, Murphy N, Randell T, Cosgrove KE, Dunne MJ, Banerjee I.

Orphanet J Rare Dis. 2016 Dec 1;11(1):163.


mTOR Inhibitors for the Treatment of Severe Congenital Hyperinsulinism: Perspectives on Limited Therapeutic Success.

Szymanowski M, Estebanez MS, Padidela R, Han B, Mosinska K, Stevens A, Damaj L, Pihan-Le Bars F, Lascouts E, Reynaud R, Ferreira C, Bansept C, de Lonlay P, Saint-Martin C, Dunne MJ, Banerjee I, Arnoux JB.

J Clin Endocrinol Metab. 2016 Dec;101(12):4719-4729. Epub 2016 Oct 3.


Key Matrix Proteins Within the Pancreatic Islet Basement Membrane Are Differentially Digested During Human Islet Isolation.

Cross SE, Vaughan RH, Willcox AJ, McBride AJ, Abraham AA, Han B, Johnson JD, Maillard E, Bateman PA, Ramracheya RD, Rorsman P, Kadler KE, Dunne MJ, Hughes SJ, Johnson PR.

Am J Transplant. 2017 Feb;17(2):451-461. doi: 10.1111/ajt.13975. Epub 2016 Sep 6.


Enhanced Islet Cell Nucleomegaly Defines Diffuse Congenital Hyperinsulinism in Infancy but Not Other Forms of the Disease.

Han B, Newbould M, Batra G, Cheesman E, Craigie RJ, Mohamed Z, Rigby L, Padidela R, Skae M, Mironov A, Starborg T, Kadler KE, Cosgrove KE, Banerjee I, Dunne MJ.

Am J Clin Pathol. 2016 Jun;145(6):757-68. doi: 10.1093/ajcp/aqw075.


Feeding Problems Are Persistent in Children with Severe Congenital Hyperinsulinism.

Banerjee I, Forsythe L, Skae M, Avatapalle HB, Rigby L, Bowden LE, Craigie R, Padidela R, Ehtisham S, Patel L, Cosgrove KE, Dunne MJ, Clayton PE.

Front Endocrinol (Lausanne). 2016 Feb 9;7:8. doi: 10.3389/fendo.2016.00008. eCollection 2016.


Altered Phenotype of β-Cells and Other Pancreatic Cell Lineages in Patients With Diffuse Congenital Hyperinsulinism in Infancy Caused by Mutations in the ATP-Sensitive K-Channel.

Salisbury RJ, Han B, Jennings RE, Berry AA, Stevens A, Mohamed Z, Sugden SA, De Krijger R, Cross SE, Johnson PP, Newbould M, Cosgrove KE, Hanley KP, Banerjee I, Dunne MJ, Hanley NA.

Diabetes. 2015 Sep;64(9):3182-8. doi: 10.2337/db14-1202. Epub 2015 Apr 30.


Increased plasma incretin concentrations identifies a subset of patients with persistent congenital hyperinsulinism without KATP channel gene defects.

Shi Y, Avatapalle HB, Skae MS, Padidela R, Newbould M, Rigby L, Flanagan SE, Ellard S, Rahier J, Clayton PE, Dunne MJ, Banerjee I, Cosgrove KE.

J Pediatr. 2015 Jan;166(1):191-4. doi: 10.1016/j.jpeds.2014.09.019. Epub 2014 Oct 23.


Reduced Glycemic Variability in Diazoxide-Responsive Children with Congenital Hyperinsulinism Using Supplemental Omega-3-Polyunsaturated Fatty Acids; A Pilot Trial with MaxEPA(R.).

Skae M, Avatapalle HB, Banerjee I, Rigby L, Vail A, Foster P, Charalambous C, Bowden L, Padidela R, Patel L, Ehtisham S, Cosgrove KE, Dunne MJ, Clayton PE.

Front Endocrinol (Lausanne). 2014 Mar 12;5:31. doi: 10.3389/fendo.2014.00031. eCollection 2014.


Insulinoma in childhood: clinical, radiological, molecular and histological aspects of nine patients.

Padidela R, Fiest M, Arya V, Smith VV, Ashworth M, Rampling D, Newbould M, Batra G, James J, Wright NB, Dunne MJ, Clayton PE, Banerjee I, Hussain K.

Eur J Endocrinol. 2014 Apr 10;170(5):741-7. doi: 10.1530/EJE-13-1008. Print 2014 May.


Frailty assessment in thoracic surgery.

Dunne MJ, Abah U, Scarci M.

Interact Cardiovasc Thorac Surg. 2014 May;18(5):667-70. doi: 10.1093/icvts/ivt542. Epub 2014 Jan 27. Review.


Network analysis: a new approach to study endocrine disorders.

Stevens A, De Leonibus C, Hanson D, Dowsey AW, Whatmore A, Meyer S, Donn RP, Chatelain P, Banerjee I, Cosgrove KE, Clayton PE, Dunne MJ.

J Mol Endocrinol. 2013 Dec 19;52(1):R79-93. doi: 10.1530/JME-13-0112. Print 2014 Feb. Review.


Abnormal Neurodevelopmental Outcomes are Common in Children with Transient Congenital Hyperinsulinism.

Avatapalle HB, Banerjee I, Shah S, Pryce M, Nicholson J, Rigby L, Caine L, Didi M, Skae M, Ehtisham S, Patel L, Padidela R, Cosgrove KE, Dunne MJ, Clayton PE.

Front Endocrinol (Lausanne). 2013 May 20;4:60. doi: 10.3389/fendo.2013.00060. eCollection 2013.


Can network biology unravel the aetiology of congenital hyperinsulinism?

Stevens A, Cosgrove KE, Padidela R, Skae MS, Clayton PE, Banerjee I, Dunne MJ.

Orphanet J Rare Dis. 2013 Feb 8;8:21. doi: 10.1186/1750-1172-8-21.


Integrating genetic and imaging investigations into the clinical management of congenital hyperinsulinism.

Banerjee I, Avatapalle B, Padidela R, Stevens A, Cosgrove KE, Clayton PE, Dunne MJ.

Clin Endocrinol (Oxf). 2013 Jun;78(6):803-13. doi: 10.1111/cen.12153. Review.


In vitro recovery of ATP-sensitive potassium channels in β-cells from patients with congenital hyperinsulinism of infancy.

Powell PD, Bellanné-Chantelot C, Flanagan SE, Ellard S, Rooman R, Hussain K, Skae M, Clayton P, de Lonlay P, Dunne MJ, Cosgrove KE.

Diabetes. 2011 Apr;60(4):1223-8. doi: 10.2337/db10-1443. Epub 2011 Mar 16.


The contribution of rapid KATP channel gene mutation analysis to the clinical management of children with congenital hyperinsulinism.

Banerjee I, Skae M, Flanagan SE, Rigby L, Patel L, Didi M, Blair J, Ehtisham S, Ellard S, Cosgrove KE, Dunne MJ, Clayton PE.

Eur J Endocrinol. 2011 May;164(5):733-40. doi: 10.1530/EJE-10-1136. Epub 2011 Mar 4.


Gastric ischaemia following a fall.

Dunne MJ, Ferreira I, Thorpe B, Ajeel A, Ali H, Bailey C.

BMJ Case Rep. 2011 Jun 30;2011. pii: bcr0420114139. doi: 10.1136/bcr.04.2011.4139.


PAX4 enhances beta-cell differentiation of human embryonic stem cells.

Liew CG, Shah NN, Briston SJ, Shepherd RM, Khoo CP, Dunne MJ, Moore HD, Cosgrove KE, Andrews PW.

PLoS One. 2008 Mar 12;3(3):e1783. doi: 10.1371/journal.pone.0001783.


Glucokinase activators: molecular tools for studying the physiology of insulin-secreting cells.

Johnson D, Shepherd RM, Gill D, Gorman T, Smith DM, Dunne MJ.

Biochem Soc Trans. 2007 Nov;35(Pt 5):1208-10. Review.


Glucose-dependent modulation of insulin secretion and intracellular calcium ions by GKA50, a glucokinase activator.

Johnson D, Shepherd RM, Gill D, Gorman T, Smith DM, Dunne MJ.

Diabetes. 2007 Jun;56(6):1694-702. Epub 2007 Mar 14.


Congenital hyperinsulinism and mosaic abnormalities of the ploidy.

Giurgea I, Sanlaville D, Fournet JC, Sempoux C, Bellanné-Chantelot C, Touati G, Hubert L, Groos MS, Brunelle F, Rahier J, Henquin JC, Dunne MJ, Jaubert F, Robert JJ, Nihoul-Fékété C, Vekemans M, Junien C, de Lonlay P.

J Med Genet. 2006 Mar;43(3):248-54. Epub 2005 Jul 20.


Hyperinsulinemic hypoglycemia in Beckwith-Wiedemann syndrome due to defects in the function of pancreatic beta-cell adenosine triphosphate-sensitive potassium channels.

Hussain K, Cosgrove KE, Shepherd RM, Luharia A, Smith VV, Kassem S, Gregory JW, Sivaprasadarao A, Christesen HT, Jacobsen BB, Brusgaard K, Glaser B, Maher EA, Lindley KJ, Hindmarsh P, Dattani M, Dunne MJ.

J Clin Endocrinol Metab. 2005 Jul;90(7):4376-82. Epub 2005 Apr 5.


Contemporary strategies in the diagnosis and management of neonatal hyperinsulinaemic hypoglycaemia.

Lindley KJ, Dunne MJ.

Early Hum Dev. 2005 Jan;81(1):61-72. Epub 2004 Nov 23. Review.


Infantile hyperinsulinism associated with enteropathy, deafness and renal tubulopathy: clinical manifestations of a syndrome caused by a contiguous gene deletion located on chromosome 11p.

Hussain K, Bitner-Glindzicz M, Blaydon D, Lindley KJ, Thompson DA, Kriss T, Rajput K, Ramadan DG, Al-Mazidi Z, Cosgrove KE, Dunne MJ, Aynsley-Green A.

J Pediatr Endocrinol Metab. 2004 Dec;17(12):1613-21.


Hyperinsulinism of infancy: novel ABCC8 and KCNJ11 mutations and evidence for additional locus heterogeneity.

Tornovsky S, Crane A, Cosgrove KE, Hussain K, Lavie J, Heyman M, Nesher Y, Kuchinski N, Ben-Shushan E, Shatz O, Nahari E, Potikha T, Zangen D, Tenenbaum-Rakover Y, de Vries L, Argente J, Gracia R, Landau H, Eliakim A, Lindley K, Dunne MJ, Aguilar-Bryan L, Glaser B.

J Clin Endocrinol Metab. 2004 Dec;89(12):6224-34.


Laparoscopic diagnosis and cure of hyperinsulinism in two cases of focal adenomatous hyperplasia in infancy.

De Vroede M, Bax NM, Brusgaard K, Dunne MJ, Groenendaal F.

Pediatrics. 2004 Oct;114(4):e520-2.


Genetics and pathophysiology of hyperinsulinism in infancy.

Cosgrove KE, Shepherd RM, Fernandez EM, Natarajan A, Lindley KJ, Aynsley-Green A, Dunne MJ.

Horm Res. 2004;61(6):270-88. Epub 2004 Feb 20. Review.


Y-26763: ATP-sensitive K+ channel activation and the inhibition of insulin release from human pancreatic beta-cells.

Cosgrove KE, Straub SG, Barnes PD, Chapman J, Sharp GW, Dunne MJ.

Eur J Pharmacol. 2004 Feb 20;486(2):133-9.


Acute insulin responses to calcium and tolbutamide do not differentiate focal from diffuse congenital hyperinsulinism.

Giurgea I, Laborde K, Touati G, Bellanné-Chantelot C, Nassogne MC, Sempoux C, Jaubert F, Khoa N, Chigot V, Rahier J, Brunelle F, Nihoul-Fékété C, Dunne MJ, Stanley C, Saudubray JM, Robert JJ, de Lonlay P.

J Clin Endocrinol Metab. 2004 Feb;89(2):925-9.


Hyperinsulinism in infancy: from basic science to clinical disease.

Dunne MJ, Cosgrove KE, Shepherd RM, Aynsley-Green A, Lindley KJ.

Physiol Rev. 2004 Jan;84(1):239-75. Review.


Uncontrolled insulin secretion from a childhood pancreatic beta-cell adenoma is not due to the functional loss of ATP-sensitive potassium channels.

Hussain K, Cosgrove KE, Shepherd RM, Chapman JC, Swift SM, Smith VV, Kassem SA, Glaser B, Lindley KJ, Aynsley-Green A, Dunne MJ.

Endocr Relat Cancer. 2002 Dec;9(4):221-6.


BPDZ 154 activates adenosine 5'-triphosphate-sensitive potassium channels: in vitro studies using rodent insulin-secreting cells and islets isolated from patients with hyperinsulinism.

Cosgrove KE, Antoine MH, Lee AT, Barnes PD, de Tullio P, Clayton P, McCloy R, De Lonlay P, Nihoul-Fékété C, Robert JJ, Saudubray JM, Rahier J, Lindley KJ, Hussain K, Aynsley-Green A, Pirotte B, Lebrun P, Dunne MJ.

J Clin Endocrinol Metab. 2002 Nov;87(11):4860-8.


Peripheral channelopathies as targets for potassium channel openers.

Lawson K, Dunne MJ.

Expert Opin Investig Drugs. 2001 Jul;10(7):1345-59. Review.


Synthesis and characterization of a quinolinonic compound activating ATP-sensitive K(+) channels in endocrine and smooth muscle tissues.

Becker B, Antoine MH, Nguyen QA, Rigo B, Cosgrove KE, Barnes PD, Dunne MJ, Pirotte B, Lebrun P.

Br J Pharmacol. 2001 Sep;134(2):375-85.


Hyperinsulinism of infancy: the regulated release of insulin by KATP channel-independent pathways.

Straub SG, Cosgrove KE, Ammälä C, Shepherd RM, O'Brien RE, Barnes PD, Kuchinski N, Chapman JC, Schaeppi M, Glaser B, Lindley KJ, Sharp GW, Aynsley-Green A, Dunne MJ.

Diabetes. 2001 Feb;50(2):329-39.


A recessive contiguous gene deletion causing infantile hyperinsulinism, enteropathy and deafness identifies the Usher type 1C gene.

Bitner-Glindzicz M, Lindley KJ, Rutland P, Blaydon D, Smith VV, Milla PJ, Hussain K, Furth-Lavi J, Cosgrove KE, Shepherd RM, Barnes PD, O'Brien RE, Farndon PA, Sowden J, Liu XZ, Scanlan MJ, Malcolm S, Dunne MJ, Aynsley-Green A, Glaser B.

Nat Genet. 2000 Sep;26(1):56-60.


Glucose modulation of insulin mRNA levels is dependent on transcription factor PDX-1 and occurs independently of changes in intracellular Ca2+.

Macfarlane WM, Shepherd RM, Cosgrove KE, James RF, Dunne MJ, Docherty K.

Diabetes. 2000 Mar;49(3):418-23.


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