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Items: 1 to 50 of 89

1.

Epithelial damage and tissue γδ T cells promote a unique tumor-protective IgE response.

Crawford G, Hayes MD, Seoane RC, Ward S, Dalessandri T, Lai C, Healy E, Kipling D, Proby C, Moyes C, Green K, Best K, Haniffa M, Botto M, Dunn-Walters D, Strid J.

Nat Immunol. 2018 Jul 16. doi: 10.1038/s41590-018-0161-8. [Epub ahead of print]

PMID:
30013146
2.

Immunoglobulin gene analysis as a tool for investigating human immune responses.

Dunn-Walters D, Townsend C, Sinclair E, Stewart A.

Immunol Rev. 2018 Jul;284(1):132-147. doi: 10.1111/imr.12659.

3.

BRepertoire: a user-friendly web server for analysing antibody repertoire data.

Margreitter C, Lu HC, Townsend C, Stewart A, Dunn-Walters DK, Fraternali F.

Nucleic Acids Res. 2018 Jul 2;46(W1):W264-W270. doi: 10.1093/nar/gky276.

4.

CD1d-mediated lipid presentation by CD11c+ cells regulates intestinal homeostasis.

Sáez de Guinoa J, Jimeno R, Gaya M, Kipling D, Garzón MJ, Dunn-Walters D, Ubeda C, Barral P.

EMBO J. 2018 Mar 1;37(5). pii: e97537. doi: 10.15252/embj.201797537. Epub 2018 Jan 29.

5.

Reduced immunoglobulin gene diversity in patients with Cornelia de Lange syndrome.

Björkman A, Du L, van der Burg M, Cormier-Daire V, Borck G, Pié J, Anderlid BM, Hammarström L, Ström L, de Villartay JP, Kipling D, Dunn Walters D, Pan-Hammarström Q.

J Allergy Clin Immunol. 2018 Jan;141(1):408-411.e8. doi: 10.1016/j.jaci.2017.06.043. Epub 2017 Aug 5. No abstract available.

6.

Significant association between TNFAIP3 inactivation and biased immunoglobulin heavy chain variable region 4-34 usage in mucosa-associated lymphoid tissue lymphoma.

Moody S, Escudero-Ibarz L, Wang M, Clipson A, Ochoa Ruiz E, Dunn-Walters D, Xue X, Zeng N, Robson A, Chuang SS, Cogliatti S, Liu H, Goodlad J, Ashton-Key M, Raderer M, Bi Y, Du MQ.

J Pathol. 2017 Sep;243(1):3-8. doi: 10.1002/path.4933. Epub 2017 Aug 7.

PMID:
28682481
7.

Transitional B Cells in Early Human B Cell Development - Time to Revisit the Paradigm?

Martin VG, Wu YB, Townsend CL, Lu GH, O'Hare JS, Mozeika A, Coolen AC, Kipling D, Fraternali F, Dunn-Walters DK.

Front Immunol. 2016 Dec 2;7:546. eCollection 2016.

8.

Significant Differences in Physicochemical Properties of Human Immunoglobulin Kappa and Lambda CDR3 Regions.

Townsend CL, Laffy JM, Wu YB, Silva O'Hare J, Martin V, Kipling D, Fraternali F, Dunn-Walters DK.

Front Immunol. 2016 Sep 27;7:388. eCollection 2016.

9.

Promiscuous antibodies characterised by their physico-chemical properties: From sequence to structure and back.

Laffy JMJ, Dodev T, Macpherson JA, Townsend C, Lu HC, Dunn-Walters D, Fraternali F.

Prog Biophys Mol Biol. 2017 Sep;128:47-56. doi: 10.1016/j.pbiomolbio.2016.09.002. Epub 2016 Sep 14.

10.

Aging affects B-cell antigen receptor repertoire diversity in primary and secondary lymphoid tissues.

Tabibian-Keissar H, Hazanov L, Schiby G, Rosenthal N, Rakovsky A, Michaeli M, Shahaf GL, Pickman Y, Rosenblatt K, Melamed D, Dunn-Walters D, Mehr R, Barshack I.

Eur J Immunol. 2016 Feb;46(2):480-92. doi: 10.1002/eji.201545586. Epub 2015 Dec 20.

11.

Assessment of B Cell Repertoire in Humans.

Wu YC, Kipling D, Dunn-Walters D.

Methods Mol Biol. 2015;1343:199-218. doi: 10.1007/978-1-4939-2963-4_16.

PMID:
26420719
12.

A Reassessment of IgM Memory Subsets in Humans.

Bagnara D, Squillario M, Kipling D, Mora T, Walczak AM, Da Silva L, Weller S, Dunn-Walters DK, Weill JC, Reynaud CA.

J Immunol. 2015 Oct 15;195(8):3716-24. doi: 10.4049/jimmunol.1500753. Epub 2015 Sep 9.

13.

Correction. Immunoglobulin light chain allelic inclusion in systemic lupus erythematosus.

Fraser LD, Zhao Y, Lutalo PM, D'Cruz DP, Cason J, Silva JS, Dunn-Walters DK, Nayar S, Cope AP, Spencer J.

Eur J Immunol. 2015 Sep;45(9):2701. doi: 10.1002/eji.201570097. No abstract available.

14.

The ageing human B cell repertoire: a failure of selection?

Dunn-Walters DK.

Clin Exp Immunol. 2016 Jan;183(1):50-6. doi: 10.1111/cei.12700. Epub 2015 Oct 6. Review.

15.

Ageing of the B-cell repertoire.

Martin V, Bryan Wu YC, Kipling D, Dunn-Walters D.

Philos Trans R Soc Lond B Biol Sci. 2015 Sep 5;370(1676). pii: 20140237. doi: 10.1098/rstb.2014.0237.

16.

Age-related aspects of human IgM(+) B cell heterogeneity.

Martin V, Wu YC, Kipling D, Dunn-Walters DK.

Ann N Y Acad Sci. 2015 Dec;1362:153-63. doi: 10.1111/nyas.12823. Epub 2015 Jul 7.

17.

Immunoglobulin light chain allelic inclusion in systemic lupus erythematosus.

Fraser LD, Zhao Y, Lutalo PM, D'Cruz DP, Cason J, Silva JS, Dunn-Walters DK, Nayar S, Cope AP, Spencer J.

Eur J Immunol. 2015 Aug;45(8):2409-19. doi: 10.1002/eji.201545599. Epub 2015 Jun 24. Erratum in: Eur J Immunol. 2015 Sep;45(9):2701.

18.

Monoclonal paraprotein influences baseline B-cell repertoire diversity and perturbates influenza vaccination-induced B-cell response.

Tete SM, Kipling D, Westra J, de Haan A, Bijl M, Dunn-Walters DK, Sahota SS, Bos NA.

Exp Hematol. 2015 Jun;43(6):439-47.e1. doi: 10.1016/j.exphem.2015.02.005. Epub 2015 Mar 18.

PMID:
25795522
19.

Immunoglobulin kappa variable region gene selection during early human B cell development in health and systemic lupus erythematosus.

Hehle V, Fraser LD, Tahir R, Kipling D, Wu YC, Lutalo PM, Cason J, Choong L, D'Cruz DP, Cope AP, Dunn-Walters DK, Spencer J.

Mol Immunol. 2015 Jun;65(2):215-23. doi: 10.1016/j.molimm.2015.01.017. Epub 2015 Feb 17.

PMID:
25700344
20.

Immunoglobulin gene repertoire diversification and selection in the stomach - from gastritis to gastric lymphomas.

Michaeli M, Tabibian-Keissar H, Schiby G, Shahaf G, Pickman Y, Hazanov L, Rosenblatt K, Dunn-Walters DK, Barshack I, Mehr R.

Front Immunol. 2014 Jun 3;5:264. doi: 10.3389/fimmu.2014.00264. eCollection 2014.

21.

Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity.

Sabouri Z, Schofield P, Horikawa K, Spierings E, Kipling D, Randall KL, Langley D, Roome B, Vazquez-Lombardi R, Rouet R, Hermes J, Chan TD, Brink R, Dunn-Walters DK, Christ D, Goodnow CC.

Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):E2567-75. doi: 10.1073/pnas.1406974111. Epub 2014 May 12.

22.

Immunogenetics and transplantation.

Davenport MP, Dunn-Walters DK.

Curr Opin Immunol. 2013 Oct;25(5):606-7. doi: 10.1016/j.coi.2013.09.001. Epub 2013 Sep 26. No abstract available.

PMID:
24075812
23.

Human lymphocyte repertoires in ageing.

Boyd SD, Liu Y, Wang C, Martin V, Dunn-Walters DK.

Curr Opin Immunol. 2013 Aug;25(4):511-5. doi: 10.1016/j.coi.2013.07.007. Epub 2013 Aug 28. Review.

24.

BCR CDR3 length distributions differ between blood and spleen and between old and young patients, and TCR distributions can be used to detect myelodysplastic syndrome.

Pickman Y, Dunn-Walters D, Mehr R.

Phys Biol. 2013 Oct;10(5):056001. doi: 10.1088/1478-3975/10/5/056001. Epub 2013 Aug 22.

PMID:
23965732
25.

Yersinia enterocolitica provides the link between thyroid-stimulating antibodies and their germline counterparts in Graves' disease.

Hargreaves CE, Grasso M, Hampe CS, Stenkova A, Atkinson S, Joshua GW, Wren BW, Buckle AM, Dunn-Walters D, Banga JP.

J Immunol. 2013 Jun 1;190(11):5373-81. doi: 10.4049/jimmunol.1203412. Epub 2013 Apr 29.

26.

Granulocyte colony stimulating factor exacerbates antineutrophil cytoplasmic antibody vasculitis.

Freeley SJ, Coughlan AM, Popat RJ, Dunn-Walters DK, Robson MG.

Ann Rheum Dis. 2013 Jun;72(6):1053-8. doi: 10.1136/annrheumdis-2012-202160. Epub 2012 Oct 19.

PMID:
23087180
27.

PCR amplification and high throughput sequencing of immunoglobulin heavy chain genes from formalin-fixed paraffin-embedded human biopsies.

Tabibian-Keissar H, Schibby G, Michaeli M, Rakovsky-Shapira A, Azogui-Rosenthal N, Dunn-Walters DK, Rosenblatt K, Mehr R, Barshack I.

Exp Mol Pathol. 2013 Feb;94(1):182-7. doi: 10.1016/j.yexmp.2012.08.002. Epub 2012 Aug 27.

PMID:
22944223
28.

A novel chronic lymphocytic leukemia subset expressing mutated IGHV3-7-encoded rheumatoid factor B-cell receptors that are functionally proficient.

Hoogeboom R, Wormhoudt TA, Schipperus MR, Langerak AW, Dunn-Walters DK, Guikema JE, Bende RJ, van Noesel CJ.

Leukemia. 2013 Mar;27(3):738-40. doi: 10.1038/leu.2012.238. Epub 2012 Aug 20. No abstract available.

PMID:
22902363
29.

Age-Related Changes in Human Peripheral Blood IGH Repertoire Following Vaccination.

Wu YC, Kipling D, Dunn-Walters DK.

Front Immunol. 2012 Jul 9;3:193. doi: 10.3389/fimmu.2012.00193. eCollection 2012.

30.

B cell immunosenescence: different features of naive and memory B cells in elderly.

Buffa S, Bulati M, Pellicanò M, Dunn-Walters DK, Wu YC, Candore G, Vitello S, Caruso C, Colonna-Romano G.

Biogerontology. 2011 Oct;12(5):473-83. doi: 10.1007/s10522-011-9353-4. Epub 2011 Aug 31.

PMID:
21879287
31.

Vaccination-induced changes in human B-cell repertoire and pneumococcal IgM and IgA antibody at different ages.

Ademokun A, Wu YC, Martin V, Mitra R, Sack U, Baxendale H, Kipling D, Dunn-Walters DK.

Aging Cell. 2011 Dec;10(6):922-30. doi: 10.1111/j.1474-9726.2011.00732.x. Epub 2011 Aug 10.

32.

The relationship between CD27 negative and positive B cell populations in human peripheral blood.

Wu YC, Kipling D, Dunn-Walters DK.

Front Immunol. 2011 Dec 26;2:81. doi: 10.3389/fimmu.2011.00081. eCollection 2011.

33.

B cells and immunosenescence: a focus on IgG+IgD-CD27- (DN) B cells in aged humans.

Bulati M, Buffa S, Candore G, Caruso C, Dunn-Walters DK, Pellicanò M, Wu YC, Colonna Romano G.

Ageing Res Rev. 2011 Apr;10(2):274-84. doi: 10.1016/j.arr.2010.12.002. Epub 2010 Dec 23. Review.

PMID:
21185406
34.

IgA-producing plasma cells originate from germinal centers that are induced by B-cell receptor engagement in humans.

Barone F, Vossenkamper A, Boursier L, Su W, Watson A, John S, Dunn-Walters DK, Fields P, Wijetilleka S, Edgeworth JD, Spencer J.

Gastroenterology. 2011 Mar;140(3):947-56. doi: 10.1053/j.gastro.2010.12.005. Epub 2010 Dec 11.

PMID:
21147106
35.

Ig gene diversification and selection in follicular lymphoma, diffuse large B cell lymphoma and primary central nervous system lymphoma revealed by lineage tree and mutation analyses.

Zuckerman NS, McCann KJ, Ottensmeier CH, Barak M, Shahaf G, Edelman H, Dunn-Walters D, Abraham RS, Stevenson FK, Mehr R.

Int Immunol. 2010 Nov;22(11):875-87. doi: 10.1093/intimm/dxq441. Epub 2010 Nov 8.

PMID:
21059768
36.

Somatic hypermutation and antigen-driven selection of B cells are altered in autoimmune diseases.

Zuckerman NS, Hazanov H, Barak M, Edelman H, Hess S, Shcolnik H, Dunn-Walters D, Mehr R.

J Autoimmun. 2010 Dec;35(4):325-35. doi: 10.1016/j.jaut.2010.07.004. Epub 2010 Aug 19.

PMID:
20727711
37.

B cell repertoire and ageing.

Dunn-Walters DK, Ademokun AA.

Curr Opin Immunol. 2010 Aug;22(4):514-20. doi: 10.1016/j.coi.2010.04.009. Epub 2010 May 25. Review.

PMID:
20537880
38.

Mathematical analysis of antigen selection in somatically mutated immunoglobulin genes associated with autoimmunity.

MacDonald CM, Boursier L, D'Cruz DP, Dunn-Walters DK, Spencer J.

Lupus. 2010 Sep;19(10):1161-70. doi: 10.1177/0961203310367657. Epub 2010 May 25.

PMID:
20501523
39.

High-throughput immunoglobulin repertoire analysis distinguishes between human IgM memory and switched memory B-cell populations.

Wu YC, Kipling D, Leong HS, Martin V, Ademokun AA, Dunn-Walters DK.

Blood. 2010 Aug 19;116(7):1070-8. doi: 10.1182/blood-2010-03-275859. Epub 2010 May 10.

40.

Ectopic GC in the thymus of myasthenia gravis patients show characteristics of normal GC.

Zuckerman NS, Howard WA, Bismuth J, Gibson K, Edelman H, Berrih-Aknin S, Dunn-Walters D, Mehr R.

Eur J Immunol. 2010 Apr;40(4):1150-61. doi: 10.1002/eji.200939914.

41.

The ageing B cell population: composition and function.

Ademokun A, Wu YC, Dunn-Walters D.

Biogerontology. 2010 Apr;11(2):125-37. doi: 10.1007/s10522-009-9256-9. Epub 2009 Nov 25. Review.

PMID:
19937382
42.

Clonal relationships between thyroid-stimulating hormone receptor-stimulating antibodies illustrate the effect of hypermutation on antibody function.

Padoa CJ, Larsen SL, Hampe CS, Gilbert JA, Dagdan E, Hegedus L, Dunn-Walters D, Banga JP.

Immunology. 2010 Feb;129(2):300-8. doi: 10.1111/j.1365-2567.2009.03184.x. Epub 2009 Oct 21.

43.

Mechanisms of immunosenescence.

Caruso C, Buffa S, Candore G, Colonna-Romano G, Dunn-Walters D, Kipling D, Pawelec G.

Immun Ageing. 2009 Jul 22;6:10. doi: 10.1186/1742-4933-6-10.

44.

B cells and aging: molecules and mechanisms.

Cancro MP, Hao Y, Scholz JL, Riley RL, Frasca D, Dunn-Walters DK, Blomberg BB.

Trends Immunol. 2009 Jul;30(7):313-8. doi: 10.1016/j.it.2009.04.005. Epub 2009 Jun 18. Review.

45.

Antisense transcripts of V(D)J rearrangements; artifacts caused by false priming?

Zhao Y, Dunn-Walters DK, Barone F, Spencer J.

Mol Immunol. 2009 Jul;46(11-12):2357-62. doi: 10.1016/j.molimm.2009.03.020. Epub 2009 Apr 28.

PMID:
19403175
46.

Generation of Immunoglobulin diversity in human gut-associated lymphoid tissue.

Spencer J, Barone F, Dunn-Walters D.

Semin Immunol. 2009 Jun;21(3):139-46. doi: 10.1016/j.smim.2009.01.003. Epub 2009 Feb 23. Review.

PMID:
19233686
47.

B-cell diversity decreases in old age and is correlated with poor health status.

Gibson KL, Wu YC, Barnett Y, Duggan O, Vaughan R, Kondeatis E, Nilsson BO, Wikby A, Kipling D, Dunn-Walters DK.

Aging Cell. 2009 Feb;8(1):18-25. doi: 10.1111/j.1474-9726.2008.00443.x. Epub 2008 Nov 5.

48.

B-cell clonal diversification and gut-lymph node trafficking in ulcerative colitis revealed using lineage tree analysis.

Tabibian-Keissar H, Zuckerman NS, Barak M, Dunn-Walters DK, Steiman-Shimony A, Chowers Y, Ofek E, Rosenblatt K, Schiby G, Mehr R, Barshack I.

Eur J Immunol. 2008 Sep;38(9):2600-9. doi: 10.1002/eji.200838333.

49.

Lambda light chain revision in the human intestinal IgA response.

Su W, Gordon JN, Barone F, Boursier L, Turnbull W, Mendis S, Dunn-Walters DK, Spencer J.

J Immunol. 2008 Jul 15;181(2):1264-71.

50.

A regulatory role for NBS1 in strand-specific mutagenesis during somatic hypermutation.

Du L, Dunn-Walters DK, Chrzanowska KH, Stankovic T, Kotnis A, Li X, Lu J, Eggertsen G, Brittain C, Popov SW, Gennery AR, Taylor AM, Pan-Hammarström Q.

PLoS One. 2008 Jun 25;3(6):e2482. doi: 10.1371/journal.pone.0002482.

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