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Items: 17

1.

Direct observation of intermediates in the SufS cysteine desulfurase reaction reveals functional roles of conserved active-site residues.

Blahut M, Wise CE, Bruno MR, Dong G, Makris TM, Frantom PA, Dunkle JA, Outten FW.

J Biol Chem. 2019 Aug 16;294(33):12444-12458. doi: 10.1074/jbc.RA119.009471. Epub 2019 Jun 27.

PMID:
31248989
2.

Regulation of cyclic oligoadenylate synthesis by the Staphylococcus epidermidis Cas10-Csm complex.

Nasef M, Muffly MC, Beckman AB, Rowe SJ, Walker FC, Hatoum-Aslan A, Dunkle JA.

RNA. 2019 Aug;25(8):948-962. doi: 10.1261/rna.070417.119. Epub 2019 May 10.

PMID:
31076459
3.

Structural Evidence for Dimer-Interface-Driven Regulation of the Type II Cysteine Desulfurase, SufS.

Dunkle JA, Bruno MR, Outten FW, Frantom PA.

Biochemistry. 2019 Feb 12;58(6):687-696. doi: 10.1021/acs.biochem.8b01122. Epub 2019 Jan 7.

4.

Mechanism of tRNA-mediated +1 ribosomal frameshifting.

Hong S, Sunita S, Maehigashi T, Hoffer ED, Dunkle JA, Dunham CM.

Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):11226-11231. doi: 10.1073/pnas.1809319115. Epub 2018 Sep 27.

5.

Molecular determinants for CRISPR RNA maturation in the Cas10-Csm complex and roles for non-Cas nucleases.

Walker FC, Chou-Zheng L, Dunkle JA, Hatoum-Aslan A.

Nucleic Acids Res. 2017 Feb 28;45(4):2112-2123. doi: 10.1093/nar/gkw891.

6.

Defining the mRNA recognition signature of a bacterial toxin protein.

Schureck MA, Dunkle JA, Maehigashi T, Miles SJ, Dunham CM.

Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13862-7. doi: 10.1073/pnas.1512959112. Epub 2015 Oct 27.

7.

Mechanisms of mRNA frame maintenance and its subversion during translation of the genetic code.

Dunkle JA, Dunham CM.

Biochimie. 2015 Jul;114:90-6. doi: 10.1016/j.biochi.2015.02.007. Epub 2015 Feb 21. Review.

8.

Structural insights into translational recoding by frameshift suppressor tRNASufJ.

Fagan CE, Maehigashi T, Dunkle JA, Miles SJ, Dunham CM.

RNA. 2014 Dec;20(12):1944-54. doi: 10.1261/rna.046953.114. Epub 2014 Oct 28.

9.

Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.

Maehigashi T, Dunkle JA, Miles SJ, Dunham CM.

Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12740-5. doi: 10.1073/pnas.1409436111. Epub 2014 Aug 15.

10.

Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA.

Dunkle JA, Vinal K, Desai PM, Zelinskaya N, Savic M, West DM, Conn GL, Dunham CM.

Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6275-80. doi: 10.1073/pnas.1402789111. Epub 2014 Apr 9.

11.

Reorganization of an intersubunit bridge induced by disparate 16S ribosomal ambiguity mutations mimics an EF-Tu-bound state.

Fagan CE, Dunkle JA, Maehigashi T, Dang MN, Devaraj A, Miles SJ, Qin D, Fredrick K, Dunham CM.

Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9716-21. doi: 10.1073/pnas.1301585110. Epub 2013 Apr 29.

12.

An Introduction to the Structure and Function of the Ribosome.

Dunkle JA, Cate JH.

EcoSal Plus. 2013 Feb;5(2). doi: 10.1128/ecosal.2.5.2.

PMID:
26442932
13.

The mechanisms of RNA SHAPE chemistry.

McGinnis JL, Dunkle JA, Cate JH, Weeks KM.

J Am Chem Soc. 2012 Apr 18;134(15):6617-24. doi: 10.1021/ja2104075. Epub 2012 Apr 5. Erratum in: J Am Chem Soc. 2012 Jul 25;134(29):12319.

14.

Structures of the bacterial ribosome in classical and hybrid states of tRNA binding.

Dunkle JA, Wang L, Feldman MB, Pulk A, Chen VB, Kapral GJ, Noeske J, Richardson JS, Blanchard SC, Cate JH.

Science. 2011 May 20;332(6032):981-4. doi: 10.1126/science.1202692.

15.

Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action.

Dunkle JA, Xiong L, Mankin AS, Cate JH.

Proc Natl Acad Sci U S A. 2010 Oct 5;107(40):17152-7. doi: 10.1073/pnas.1007988107. Epub 2010 Sep 27.

16.

Ribosome structure and dynamics during translocation and termination.

Dunkle JA, Cate JH.

Annu Rev Biophys. 2010;39:227-44. doi: 10.1146/annurev.biophys.37.032807.125954. Review.

PMID:
20192776
17.

Structures of the ribosome in intermediate states of ratcheting.

Zhang W, Dunkle JA, Cate JH.

Science. 2009 Aug 21;325(5943):1014-7. doi: 10.1126/science.1175275.

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