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Items: 1 to 50 of 161

1.

Pre-irradiation intensive induction and marrow-ablative consolidation chemotherapy in young children with newly diagnosed high-grade brainstem gliomas: report of the "head-start" I and II clinical trials.

Osorio DS, Patel N, Ji L, Sposto R, Stanek J, Gardner SL, Allen JC, Cornelius A, McCowage GB, Termuhlen A, Dunkel IJ, Comito M, Garvin J, Finlay JL.

J Neurooncol. 2018 Nov 3. doi: 10.1007/s11060-018-03003-z. [Epub ahead of print]

PMID:
30392092
2.

Metastases and death rates after primary enucleation of unilateral retinoblastoma in the USA 2007-2017.

Lu JE, Francis JH, Dunkel IJ, Shields CL, Yu MD, Berry JL, Kogachi K, Skalet AH, Miller AK, Santapuram PR, Daniels AB, Abramson DH.

Br J Ophthalmol. 2018 Oct 25. pii: bjophthalmol-2018-312915. doi: 10.1136/bjophthalmol-2018-312915. [Epub ahead of print]

PMID:
30361279
3.

Current Treatment of Bilateral Retinoblastoma: The Impact of Intraarterial and Intravitreous Chemotherapy.

Francis JH, Roosipu N, Levin AM, Brodie SE, Dunkel IJ, Gobin YP, Abramson DH.

Neoplasia. 2018 Aug;20(8):757-763. doi: 10.1016/j.neo.2018.05.007. Epub 2018 Jun 22.

4.

Convection-enhanced delivery for diffuse intrinsic pontine glioma: a single-centre, dose-escalation, phase 1 trial.

Souweidane MM, Kramer K, Pandit-Taskar N, Zhou Z, Haque S, Zanzonico P, Carrasquillo JA, Lyashchenko SK, Thakur SB, Donzelli M, Turner RS, Lewis JS, Cheung NV, Larson SM, Dunkel IJ.

Lancet Oncol. 2018 Aug;19(8):1040-1050. doi: 10.1016/S1470-2045(18)30322-X. Epub 2018 Jun 18. Erratum in: Lancet Oncol. 2018 Aug;19(8):e382.

PMID:
29914796
5.

A Secondary Mutation in BRAF Confers Resistance to RAF Inhibition in a BRAFV600E-Mutant Brain Tumor.

Wang J, Yao Z, Jonsson P, Allen AN, Qin ACR, Uddin S, Dunkel IJ, Petriccione M, Manova K, Haque S, Rosenblum MK, Pisapia DJ, Rosen N, Taylor BS, Pratilas CA.

Cancer Discov. 2018 Sep;8(9):1130-1141. doi: 10.1158/2159-8290.CD-17-1263. Epub 2018 Jun 7.

PMID:
29880583
6.

Vision-Targeted Health-Related Quality of Life in Adult Survivors of Retinoblastoma.

Friedman DN, Chou JF, Francis JH, Sklar CA, Li Y, McCabe M, Robison LL, Kleinerman RA, Oeffinger KC, Abramson DH, Dunkel IJ, Ford JS.

JAMA Ophthalmol. 2018 Jun 1;136(6):637-641. doi: 10.1001/jamaophthalmol.2018.1082.

PMID:
29710339
7.

Total retinal detachments due to retinoblastoma: Outcomes following intra-arterial chemotherapy/ophthalmic artery chemosurgery.

Rowlands MA, Mondesire-Crump I, Levin A, Mauguen A, Francis JH, Dunkel IJ, Brodie SE, Gobin YP, Abramson DH.

PLoS One. 2018 Apr 26;13(4):e0195395. doi: 10.1371/journal.pone.0195395. eCollection 2018.

8.

Patterns of relapse for children with localized intracranial ependymoma.

De B, Khakoo Y, Souweidane MM, Dunkel IJ, Patel SH, Gilheeney SW, De Braganca KC, Karajannis MA, Wolden SL.

J Neurooncol. 2018 Jun;138(2):435-445. doi: 10.1007/s11060-018-2815-7. Epub 2018 Mar 6.

PMID:
29511977
9.

BRIM-P: A phase I, open-label, multicenter, dose-escalation study of vemurafenib in pediatric patients with surgically incurable, BRAF mutation-positive melanoma.

Chisholm JC, Suvada J, Dunkel IJ, Casanova M, Zhang W, Ritchie N, Choi Y, Park J, Das Thakur M, Simko S, Wan Rachel Tam N, Ferrari A.

Pediatr Blood Cancer. 2018 May;65(5):e26947. doi: 10.1002/pbc.26947. Epub 2018 Jan 19.

PMID:
29350463
10.

Phase II study of ipilimumab in adolescents with unresectable stage III or IV malignant melanoma.

Geoerger B, Bergeron C, Gore L, Sender L, Dunkel IJ, Herzog C, Brochez L, Cruz O, Nysom K, Berghorn E, Simsek B, Shen J, Pappo A.

Eur J Cancer. 2017 Nov;86:358-363. doi: 10.1016/j.ejca.2017.09.032. Epub 2017 Nov 5.

PMID:
29100190
11.

Long-term outcomes of adult medulloblastoma patients treated with radiotherapy.

De B, Beal K, De Braganca KC, Souweidane MM, Dunkel IJ, Khakoo Y, Gilheeney SW, DeAngelis LM, Menzel P, Patel SH, Wolden SL.

J Neurooncol. 2018 Jan;136(1):95-104. doi: 10.1007/s11060-017-2627-1. Epub 2017 Oct 10.

PMID:
29019042
12.

A phase II study of radioimmunotherapy with intraventricular 131 I-3F8 for medulloblastoma.

Kramer K, Pandit-Taskar N, Humm JL, Zanzonico PB, Haque S, Dunkel IJ, Wolden SL, Donzelli M, Goldman DA, Lewis JS, Lyashchenko SK, Khakoo Y, Carrasquillo JA, Souweidane MM, Greenfield JP, Lyden D, De Braganca KD, Gilheeney SW, Larson SM, Cheung NV.

Pediatr Blood Cancer. 2018 Jan;65(1). doi: 10.1002/pbc.26754. Epub 2017 Sep 22.

PMID:
28940863
13.

The Effect of Ophthalmic Artery Chemosurgery on Immune Function in Retinoblastoma Patients: A Single Institution Retrospective Analysis.

Fischer C, Petriccione M, Vitolano S, Guarini E, Davis ME, Dunkel IJ.

J Pediatr Hematol Oncol. 2017 Oct;39(7):555-559. doi: 10.1097/MPH.0000000000000968.

14.

Tandem thiotepa with autologous hematopoietic cell rescue in patients with recurrent, refractory, or poor prognosis solid tumor malignancies.

Osorio DS, Dunkel IJ, Cervone KA, Goyal RK, Steve Lo KM, Finlay JL, Gardner SL.

Pediatr Blood Cancer. 2018 Jan;65(1). doi: 10.1002/pbc.26776. Epub 2017 Sep 14.

PMID:
28905508
15.

Novel activating BRAF fusion identifies a recurrent alternative mechanism for ERK activation in pediatric Langerhans cell histiocytosis.

Zarnegar S, Durham BH, Khattar P, Shukla NN, Benayed R, Lacouture ME, Lavi E, Lyden DC, Diamond EL, Dunkel IJ, Abdel-Wahab O.

Pediatr Blood Cancer. 2018 Jan;65(1). doi: 10.1002/pbc.26699. Epub 2017 Jul 27.

PMID:
28748614
16.

Reduced-volume radiotherapy for patients with localized intracranial nongerminoma germ cell tumors.

De B, Cahlon O, Dunkel IJ, De Braganca KC, Khakoo Y, Gilheeney SW, Souweidane MM, Wolden SL.

J Neurooncol. 2017 Sep;134(2):349-356. doi: 10.1007/s11060-017-2532-7. Epub 2017 Jun 28.

17.

Second primary malignancies in retinoblastoma patients treated with intra-arterial chemotherapy: the first 10 years.

Habib LA, Francis JH, Fabius AW, Gobin PY, Dunkel IJ, Abramson DH.

Br J Ophthalmol. 2018 Feb;102(2):272-275. doi: 10.1136/bjophthalmol-2017-310328. Epub 2017 Jun 9.

PMID:
28600304
18.

A phase I study of single-agent perifosine for recurrent or refractory pediatric CNS and solid tumors.

Becher OJ, Millard NE, Modak S, Kushner BH, Haque S, Spasojevic I, Trippett TM, Gilheeney SW, Khakoo Y, Lyden DC, De Braganca KC, Kolesar JM, Huse JT, Kramer K, Cheung NV, Dunkel IJ.

PLoS One. 2017 Jun 5;12(6):e0178593. doi: 10.1371/journal.pone.0178593. eCollection 2017.

19.

A pediatric trial of radiation/cetuximab followed by irinotecan/cetuximab in newly diagnosed diffuse pontine gliomas and high-grade astrocytomas: A Pediatric Oncology Experimental Therapeutics Investigators' Consortium study.

Macy ME, Kieran MW, Chi SN, Cohen KJ, MacDonald TJ, Smith AA, Etzl MM, Kuei MC, Donson AM, Gore L, DiRenzo J, Trippett TM, Ostrovnaya I, Narendran A, Foreman NK, Dunkel IJ.

Pediatr Blood Cancer. 2017 Nov;64(11). doi: 10.1002/pbc.26621. Epub 2017 May 24.

20.

Ophthalmic artery chemosurgery for eyes with advanced retinoblastoma.

Abramson DH, Fabius AW, Francis JH, Marr BP, Dunkel IJ, Brodie SE, Escuder A, Gobin YP.

Ophthalmic Genet. 2017 Jan-Feb;38(1):16-21. doi: 10.1080/13816810.2016.1244695. Epub 2017 Jan 17.

21.

A phase I study of perifosine with temsirolimus for recurrent pediatric solid tumors.

Becher OJ, Gilheeney SW, Khakoo Y, Lyden DC, Haque S, De Braganca KC, Kolesar JM, Huse JT, Modak S, Wexler LH, Kramer K, Spasojevic I, Dunkel IJ.

Pediatr Blood Cancer. 2017 Jul;64(7). doi: 10.1002/pbc.26409. Epub 2016 Dec 30.

PMID:
28035748
22.

A phase IIa study of afuresertib, an oral pan-AKT inhibitor, in patients with Langerhans cell histiocytosis.

Arceci RJ, Allen CE, Dunkel IJ, Jacobsen E, Whitlock J, Vassallo R, Morris SR, Portnoy A, Reedy BA, Smith DA, Noble R, Murnane A, Cornfeld M, Rodriguez-Galindo C, Heaney ML, McClain K, Vaiselbuh S.

Pediatr Blood Cancer. 2017 May;64(5). doi: 10.1002/pbc.26325. Epub 2016 Nov 2.

PMID:
27804235
23.

A phase I/Ib trial targeting the Pi3k/Akt pathway using perifosine: Long-term progression-free survival of patients with resistant neuroblastoma.

Kushner BH, Cheung NV, Modak S, Becher OJ, Basu EM, Roberts SS, Kramer K, Dunkel IJ.

Int J Cancer. 2017 Jan 15;140(2):480-484. doi: 10.1002/ijc.30440. Epub 2016 Sep 30.

24.

Psychiatric manifestations as initial presentation for pediatric CNS germ cell tumors, a case series.

Malbari F, Gershon TR, Garvin JH, Allen JC, Khakoo Y, Levy AS, Dunkel IJ.

Childs Nerv Syst. 2016 Aug;32(8):1359-62. doi: 10.1007/s00381-016-3145-8. Epub 2016 Jun 16.

25.

Simultaneous Bilateral Ophthalmic Artery Chemosurgery for Bilateral Retinoblastoma (Tandem Therapy).

Abramson DH, Marr BP, Francis JH, Dunkel IJ, Fabius AW, Brodie SE, Mondesire-Crump I, Gobin YP.

PLoS One. 2016 Jun 3;11(6):e0156806. doi: 10.1371/journal.pone.0156806. eCollection 2016.

26.

Meningioma after radiotherapy for malignancy.

Morgenstern PF, Shah K, Dunkel IJ, Reiner AS, Khakoo Y, Rosenblum MK, Gutin P.

J Clin Neurosci. 2016 Aug;30:93-97. doi: 10.1016/j.jocn.2016.02.002. Epub 2016 Apr 8.

27.

Phase I trial of p28 (NSC745104), a non-HDM2-mediated peptide inhibitor of p53 ubiquitination in pediatric patients with recurrent or progressive central nervous system tumors: A Pediatric Brain Tumor Consortium Study.

Lulla RR, Goldman S, Yamada T, Beattie CW, Bressler L, Pacini M, Pollack IF, Fisher PG, Packer RJ, Dunkel IJ, Dhall G, Wu S, Onar A, Boyett JM, Fouladi M.

Neuro Oncol. 2016 Sep;18(9):1319-25. doi: 10.1093/neuonc/now047. Epub 2016 Mar 28.

28.

Twenty-Year Collaboration Between North American and South American Retinoblastoma Programs.

Chantada GL, Dunkel IJ, Schaiquevich PS, Grynszpancholc EL, Francis J, Ceciliano A, Zubizarreta PA, Fandiño AC, Abramson DH.

J Glob Oncol. 2016 Mar 30;2(6):347-352. doi: 10.1200/JGO.2015.002782. eCollection 2016 Dec. No abstract available.

29.

Intra-Arterial Chemotherapy (Ophthalmic Artery Chemosurgery) for Group D Retinoblastoma.

Abramson DH, Daniels AB, Marr BP, Francis JH, Brodie SE, Dunkel IJ, Gobin YP.

PLoS One. 2016 Jan 12;11(1):e0146582. doi: 10.1371/journal.pone.0146582. eCollection 2016.

30.

Chronic medical conditions in adult survivors of retinoblastoma: Results of the Retinoblastoma Survivor Study.

Friedman DN, Chou JF, Oeffinger KC, Kleinerman RA, Ford JS, Sklar CA, Li Y, McCabe MS, Robison LL, Marr BP, Abramson DH, Dunkel IJ.

Cancer. 2016 Mar 1;122(5):773-81. doi: 10.1002/cncr.29704. Epub 2016 Jan 11.

31.

Advanced Unilateral Retinoblastoma: The Impact of Ophthalmic Artery Chemosurgery on Enucleation Rate and Patient Survival at MSKCC.

Abramson DH, Fabius AW, Issa R, Francis JH, Marr BP, Dunkel IJ, Gobin YP.

PLoS One. 2015 Dec 28;10(12):e0145436. doi: 10.1371/journal.pone.0145436. eCollection 2015.

32.

Intensity-Modulated Radiation Therapy With Dose Painting: A Brain-Sparing Technique for Intracranial Germ Cell Tumors.

Yang JC, Terezakis SA, Dunkel IJ, Gilheeney SW, Wolden SL.

Pediatr Blood Cancer. 2016 Apr;63(4):646-51. doi: 10.1002/pbc.25867. Epub 2015 Dec 24.

33.

INTRAVITREAL MELPHALAN AS SALVAGE THERAPY FOR REFRACTORY RETINAL AND SUBRETINAL RETINOBLASTOMA.

Francis JH, Marr BP, Brodie SE, Gobin P, Dunkel IJ, Abramson DH.

Retin Cases Brief Rep. 2016 Fall;10(4):357-60. doi: 10.1097/ICB.0000000000000262.

34.

Psychosocial Outcomes in Adult Survivors of Retinoblastoma.

Ford JS, Chou JF, Sklar CA, Oeffinger KC, Novetsky Friedman D, McCabe M, Robison LL, Kleinerman RA, Li Y, Marr BP, Abramson DH, Dunkel IJ.

J Clin Oncol. 2015 Nov 1;33(31):3608-14. doi: 10.1200/JCO.2014.60.5733. Epub 2015 Sep 28.

35.

Enucleation vs Ophthalmic Artery Chemosurgery for Advanced Intraocular Retinoblastoma: A Retrospective Analysis.

Yannuzzi NA, Francis JH, Marr BP, Belinsky I, Dunkel IJ, Gobin YP, Abramson DH.

JAMA Ophthalmol. 2015 Sep;133(9):1062-6. doi: 10.1001/jamaophthalmol.2015.2243.

36.

Pilot Study of Intensive Chemotherapy With Peripheral Hematopoietic Cell Support for Children Less Than 3 Years of Age With Malignant Brain Tumors, the CCG-99703 Phase I/II Study. A Report From the Children's Oncology Group.

Cohen BH, Geyer JR, Miller DC, Curran JG, Zhou T, Holmes E, Ingles SA, Dunkel IJ, Hilden J, Packer RJ, Pollack IF, Gajjar A, Finlay JL; Children's Oncology Group.

Pediatr Neurol. 2015 Jul;53(1):31-46. doi: 10.1016/j.pediatrneurol.2015.03.019. Epub 2015 Apr 9.

37.

Retinoblastoma.

Ortiz MV, Dunkel IJ.

J Child Neurol. 2016 Feb;31(2):227-36. doi: 10.1177/0883073815587943. Epub 2015 May 28. Review.

PMID:
26023180
38.

Early-stage non-Spitzoid cutaneous melanoma in patients younger than 22 years of age at diagnosis: long-term follow-up and survival analysis.

Stanelle EJ, Busam KJ, Rich BS, Christison-Lagay ER, Dunkel IJ, Marghoob AA, Halpern A, Coit DG, La Quaglia MP.

J Pediatr Surg. 2015 Jun;50(6):1019-23. doi: 10.1016/j.jpedsurg.2015.03.030. Epub 2015 Mar 14.

39.

Ovarian function in survivors of childhood medulloblastoma: Impact of reduced dose craniospinal irradiation and high-dose chemotherapy with autologous stem cell rescue.

Balachandar S, Dunkel IJ, Khakoo Y, Wolden S, Allen J, Sklar CA.

Pediatr Blood Cancer. 2015 Feb;62(2):317-321. doi: 10.1002/pbc.25291. Epub 2014 Oct 24.

PMID:
25346052
40.

Efficacy and toxicity of second-course ophthalmic artery chemosurgery for retinoblastoma.

Francis JH, Abramson DH, Gobin YP, Marr BP, Tendler I, Brodie SE, Dunkel IJ.

Ophthalmology. 2015 May;122(5):1016-22. doi: 10.1016/j.ophtha.2014.11.029. Epub 2015 Jan 21.

41.

Extraneural metastases of medulloblastoma: desmoplastic variants may have prolonged survival.

Young RJ, Khakoo Y, Yhu S, Wolden S, De Braganca KC, Gilheeney SW, Dunkel IJ.

Pediatr Blood Cancer. 2015 Apr;62(4):611-5. doi: 10.1002/pbc.25354. Epub 2014 Dec 11.

PMID:
25504865
42.

Risk factors for severe neutropenia following intra-arterial chemotherapy for intra-ocular retinoblastoma.

Dunkel IJ, Shi W, Salvaggio K, Marr BP, Brodie SE, Gobin YP, Abramson DH.

PLoS One. 2014 Oct 10;9(10):e108692. doi: 10.1371/journal.pone.0108692. eCollection 2014.

43.

Advances in the management of central nervous system germ cell tumors.

Millard NE, Dunkel IJ.

Curr Oncol Rep. 2014 Jul;16(7):393. doi: 10.1007/s11912-014-0393-1. Review.

PMID:
24838613
44.

Electroretinogram monitoring of dose-dependent toxicity after ophthalmic artery chemosurgery in retinoblastoma eyes: six year review.

Francis JH, Abramson DH, Gobin YP, Marr BP, Dunkel IJ, Riedel ER, Brodie SE.

PLoS One. 2014 Jan 20;9(1):e84247. doi: 10.1371/journal.pone.0084247. eCollection 2014.

45.

Whole-body magnetic resonance imaging (WB-MRI) as surveillance for subsequent malignancies in survivors of hereditary retinoblastoma: a pilot study.

Friedman DN, Lis E, Sklar CA, Oeffinger KC, Reppucci M, Fleischut MH, Francis JH, Marr B, Abramson DH, Dunkel IJ.

Pediatr Blood Cancer. 2014 Aug;61(8):1440-4. doi: 10.1002/pbc.24835. Epub 2013 Nov 1.

46.

Marker (+) CNS germ cell tumors in remission: are surveillance MRI scans necessary?

Martinez S, Khakoo Y, Gilheeney S, Kramer K, Wolden S, Souweidane M, Dunkel IJ.

Pediatr Blood Cancer. 2014 May;61(5):853-4. doi: 10.1002/pbc.24888. Epub 2013 Dec 3.

PMID:
24375894
47.

Incidence of pineal gland cyst and pineoblastoma in children with retinoblastoma during the chemoreduction era.

Abramson DH, Dunkel IJ, Marr BP, Francis J, Gobin YP.

Am J Ophthalmol. 2013 Dec;156(6):1319-20. doi: 10.1016/j.ajo.2013.09.005. No abstract available.

PMID:
24238207
48.

Carboplatin +/- topotecan ophthalmic artery chemosurgery for intraocular retinoblastoma.

Francis JH, Gobin YP, Dunkel IJ, Marr BP, Brodie SE, Jonna G, Abramson DH.

PLoS One. 2013 Aug 21;8(8):e72441. doi: 10.1371/journal.pone.0072441. eCollection 2013.

49.

Salvage/adjuvant brachytherapy after ophthalmic artery chemosurgery for intraocular retinoblastoma.

Francis JH, Barker CA, Wolden SL, McCormick B, Segal K, Cohen G, Gobin YP, Marr BP, Brodie SE, Dunkel IJ, Abramson DH.

Int J Radiat Oncol Biol Phys. 2013 Nov 1;87(3):517-23. doi: 10.1016/j.ijrobp.2013.06.2045. Epub 2013 Aug 14.

50.

In reply.

Rosen AC, Gavrilovic IT, Balagula Y, Ramaswamy V, Dickler MN, Dunkel IJ, Lacouture ME.

Oncologist. 2013;18(4):e18. doi: 10.1634/theoncologist.2012-0421. Epub 2013 Apr 10. No abstract available.

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