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Items: 13

1.

Neutrophil cytoplasts induce TH17 differentiation and skew inflammation toward neutrophilia in severe asthma.

Krishnamoorthy N, Douda DN, Br├╝ggemann TR, Ricklefs I, Duvall MG, Abdulnour RE, Martinod K, Tavares L, Wang X, Cernadas M, Israel E, Mauger DT, Bleecker ER, Castro M, Erzurum SC, Gaston BM, Jarjour NN, Wenzel S, Dunican E, Fahy JV, Irimia D, Wagner DD, Levy BD; National Heart, Lung, and Blood Institute Severe Asthma Research Program-3 Investigators.

Sci Immunol. 2018 Aug 3;3(26). pii: eaao4747. doi: 10.1126/sciimmunol.aao4747.

PMID:
30076281
2.

Pruning of the Pulmonary Vasculature in Asthma. The Severe Asthma Research Program (SARP) Cohort.

Ash SY, Rahaghi FN, Come CE, Ross JC, Colon AG, Cardet-Guisasola JC, Dunican EM, Bleecker ER, Castro M, Fahy JV, Fain SB, Gaston BM, Hoffman EA, Jarjour NN, Mauger DT, Wenzel SE, Levy BD, San Jose Estepar R, Israel E, Washko GR; SARP Investigators.

Am J Respir Crit Care Med. 2018 Jul 1;198(1):39-50. doi: 10.1164/rccm.201712-2426OC.

PMID:
29672122
3.

Refractory airway type 2 inflammation in a large subgroup of asthmatic patients treated with inhaled corticosteroids.

Peters MC, Kerr S, Dunican EM, Woodruff PG, Fajt ML, Levy BD, Israel E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, Coverstone AM, Castro M, Hastie AT, Bleecker ER, Wenzel SE, Fahy JV; National Heart, Lung and Blood Institute Severe Asthma Research Program 3.

J Allergy Clin Immunol. 2018 Mar 7. pii: S0091-6749(18)30390-7. doi: 10.1016/j.jaci.2017.12.1009. [Epub ahead of print]

PMID:
29524537
4.

Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction.

Dunican EM, Elicker BM, Gierada DS, Nagle SK, Schiebler ML, Newell JD, Raymond WW, Lachowicz-Scroggins ME, Di Maio S, Hoffman EA, Castro M, Fain SB, Jarjour NN, Israel E, Levy BD, Erzurum SC, Wenzel SE, Meyers DA, Bleecker ER, Phillips BR, Mauger DT, Gordon ED, Woodruff PG, Peters MC, Fahy JV; National Heart Lung and Blood Institute (NHLBI) Severe Asthma Research Program (SARP).

J Clin Invest. 2018 Mar 1;128(3):997-1009. doi: 10.1172/JCI95693. Epub 2018 Feb 5.

5.

Asthma and corticosteroids: time for a more precise approach to treatment.

Dunican EM, Fahy JV.

Eur Respir J. 2017 Jun 29;49(6). pii: 1701167. doi: 10.1183/13993003.01167-2017. Print 2017 Jun. No abstract available.

PMID:
28663322
6.

Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.

Lachowicz-Scroggins ME, Yuan S, Kerr SC, Dunican EM, Yu M, Carrington SD, Fahy JV.

Am J Respir Crit Care Med. 2016 Nov 15;194(10):1296-1299. No abstract available.

7.

Association Between Insomnia and Asthma Burden in the Severe Asthma Research Program (SARP) III.

Luyster FS, Strollo PJ Jr, Holguin F, Castro M, Dunican EM, Fahy J, Gaston B, Israel E, Jarjour NN, Mauger DT, Moore WC, Wenzel SE.

Chest. 2016 Dec;150(6):1242-1250. doi: 10.1016/j.chest.2016.09.020. Epub 2016 Oct 6.

8.

Biomarkers of Airway Type-2 Inflammation and Integrating Complex Phenotypes to Endotypes in Asthma.

Peters MC, Nguyen ML, Dunican EM.

Curr Allergy Asthma Rep. 2016 Oct;16(10):71. doi: 10.1007/s11882-016-0651-4. Review.

PMID:
27613654
9.

The Role of Type 2 Inflammation in the Pathogenesis of Asthma Exacerbations.

Dunican EM, Fahy JV.

Ann Am Thorac Soc. 2015 Nov;12 Suppl 2:S144-9. doi: 10.1513/AnnalsATS.201506-377AW. Review.

10.

Oxidation increases mucin polymer cross-links to stiffen airway mucus gels.

Yuan S, Hollinger M, Lachowicz-Scroggins ME, Kerr SC, Dunican EM, Daniel BM, Ghosh S, Erzurum SC, Willard B, Hazen SL, Huang X, Carrington SD, Oscarson S, Fahy JV.

Sci Transl Med. 2015 Feb 25;7(276):276ra27. doi: 10.1126/scitranslmed.3010525.

11.

A national house-staff audit of medical prophylaxis in medical patients for the PREVENTion of Venous ThromboEmbolism (PREVENT-VTE).

Adamali H, Suliman AM, Zaid H, O'Donoghue E, Burke A, Suliman AW, Salem M, O'Toole A, Yearoo AI, Javid S, Ullah I, Bolger K, Dunican E, McCullagh B, Curtin D, Lonergan MT, Dillon L, Murphy AW, Gaine S; PREVENT VTE Investigators.

Ir Med J. 2013 Nov-Dec;106(10):302-5.

PMID:
24579409
12.

Outcomes of patients presenting to a dedicated rapid access lung cancer clinic.

Dunican E, Uzbeck M, Clince J, Toner S, Royston D, Logan MP, Breathnach O, Young V, Linnane SI, Morgan RK.

Ir Med J. 2011 Oct;104(9):265-8.

PMID:
22132593
13.

Factors that predict failure in home management of an acute exacerbation of COPD.

Dunican EM, Deering BM, Ryan DM, McCormack NM, Costello RW.

Thorax. 2011 Apr;66(4):358-9. doi: 10.1136/thx.2009.125385. Epub 2010 Sep 6. No abstract available.

PMID:
20820064

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