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Factors predicting poor glycaemic control in the first two years of childhood onset type 1 diabetes in a cohort from East London, UK: Analyses using mixed effects fractional polynomial models.

Mazarello Paes V, Barrett JK, Dunger DB, Gevers EF, Taylor-Robinson DC, Viner RM, Stephenson TJ.

Pediatr Diabetes. 2019 Nov 29. doi: 10.1111/pedi.12950. [Epub ahead of print]


Temporal Trends in Maternal Food Intake Frequencies and Associations with Gestational Diabetes: The Cambridge Baby Growth Study.

Petry CJ, Ong KK, Hughes IA, Acerini CL, Dunger DB.

Nutrients. 2019 Nov 19;11(11). pii: E2822. doi: 10.3390/nu11112822.


Increases in bioactive IGF do not parallel increases in total IGF-I during growth hormone treatment of children born SGA.

Wegmann MG, Jensen RB, Thankamony A, Frystyk J, Roche E, Hoey H, Kirk J, Shaikh G, Ivarsson SA, Söder O, Dunger DB, Juul A.

J Clin Endocrinol Metab. 2019 Oct 29. pii: dgz118. doi: 10.1210/clinem/dgz118. [Epub ahead of print]


Altered triglyceride and phospholipid metabolism predates the diagnosis of gestational diabetes in obese pregnancy.

Furse S, White SL, Meek CL, Jenkins B, Petry CJ, Vieira MC, Ozanne SE, Dunger DB, Poston L, Koulman A.

Mol Omics. 2019 Dec 2;15(6):420-430. doi: 10.1039/c9mo00117d.


Evidence from 3-month-old infants shows that a combination of postnatal feeding and exposures in utero shape lipid metabolism.

Furse S, Snowden SG, Olga L, Prentice P, Ong KK, Hughes IA, Acerini CL, Dunger DB, Koulman A.

Sci Rep. 2019 Oct 4;9(1):14321. doi: 10.1038/s41598-019-50693-0.


Methylation of the C19MC microRNA locus in the placenta: association with maternal and chilhood body size.

Prats-Puig A, Xargay-Torrent S, Carreras-Badosa G, Mas-Parés B, Bassols J, Petry CJ, Girardot M, D E Zegher F, Ibáñez L, Dunger DB, Feil R, López-Bermejo A.

Int J Obes (Lond). 2019 Sep 25. doi: 10.1038/s41366-019-0450-9. [Epub ahead of print]


Feasibility of automated insulin delivery guided by continuous glucose monitoring in preterm infants.

Beardsall K, Thomson L, Elleri D, Dunger DB, Hovorka R.

Arch Dis Child Fetal Neonatal Ed. 2019 Aug 9. pii: fetalneonatal-2019-316871. doi: 10.1136/archdischild-2019-316871. [Epub ahead of print]


Reduced size at birth and persisting reductions in adiposity in recent, compared with earlier, cohorts of infants born to mothers with gestational diabetes mellitus.

Prentice PM, Olga L, Petry CJ, Simmons D, Murphy HR, Hughes IA, Acerini CL, Ong KK, Dunger DB.

Diabetologia. 2019 Nov;62(11):1977-1987. doi: 10.1007/s00125-019-4970-6. Epub 2019 Aug 9.


Young Children Have Higher Variability of Insulin Requirements: Observations During Hybrid Closed-Loop Insulin Delivery.

Dovc K, Boughton C, Tauschmann M, Thabit H, Bally L, Allen JM, Acerini CL, Arnolds S, de Beaufort C, Bergenstal RM, Campbell F, Criego A, Dunger DB, Elleri D, Evans ML, Fröhlich-Reiterer E, Hofer S, Kapellen T, Leelarathna L, Pieber TR, Rami-Merhar B, Shah VN, Sibayan J, Wilinska ME, Hovorka R; APCam11, AP@Home, and KidsAP Consortia.

Diabetes Care. 2019 Jul;42(7):1344-1347. doi: 10.2337/dc18-2625. Epub 2019 May 21.


Temporal trends without seasonal effects on gestational diabetes incidence relate to reductions in indices of insulin secretion: the Cambridge Baby Growth Study.

Petry CJ, Fisher BG, Ong KK, Hughes IA, Acerini CL, Dunger DB.

Acta Diabetol. 2019 Oct;56(10):1133-1140. doi: 10.1007/s00592-019-01354-1. Epub 2019 May 13.


Human Milk Short-Chain Fatty Acid Composition is Associated with Adiposity Outcomes in Infants.

Prentice PM, Schoemaker MH, Vervoort J, Hettinga K, Lambers TT, van Tol EAF, Acerini CL, Olga L, Petry CJ, Hughes IA, Koulman A, Ong KK, Dunger DB.

J Nutr. 2019 May 1;149(5):716-722. doi: 10.1093/jn/nxy320.


A new strategy for vascular complications in young people with type 1 diabetes mellitus.

Marcovecchio ML, Dalton RN, Daneman D, Deanfield J, Jones TW, Neil HAW, Dunger DB; Adolescent type 1 Diabetes cardio-renal Intervention Trial (AdDIT) study group.

Nat Rev Endocrinol. 2019 Jul;15(7):429-435. doi: 10.1038/s41574-019-0198-2. Review.


Effect of early glycemic control on HbA1c tracking and development of vascular complications after 5 years of childhood onset type 1 diabetes: Systematic review and meta-analysis.

Mazarello Paes V, Barrett JK, Taylor-Robinson DC, Chesters H, Charalampopoulos D, Dunger DB, Viner RM, Stephenson TJ.

Pediatr Diabetes. 2019 Aug;20(5):494-509. doi: 10.1111/pedi.12850. Epub 2019 Apr 24. Review.


Elevated high-density lipoprotein in adolescents with Type 1 diabetes is associated with endothelial dysfunction in the presence of systemic inflammation.

Chiesa ST, Charakida M, McLoughlin E, Nguyen HC, Georgiopoulos G, Motran L, Elia Y, Marcovecchio ML, Dunger DB, Dalton RN, Daneman D, Sochett E, Mahmud FH, Deanfield JE.

Eur Heart J. 2019 Nov 14;40(43):3559-3566. doi: 10.1093/eurheartj/ehz114.


Age at Menarche and Blood Pressure in Pregnancy.

Petry CJ, Ong KK, Hughes IA, Acerini CL, Dunger DB.

Pregnancy Hypertens. 2019 Jan;15:134-140. doi: 10.1016/j.preghy.2019.01.004.


Mixed-meal tolerance test to assess residual beta-cell secretion: Beyond the area-under-curve of plasma C-peptide concentration.

Ruan Y, Willemsen RH, Wilinska ME, Tauschmann M, Dunger DB, Hovorka R.

Pediatr Diabetes. 2019 May;20(3):282-285. doi: 10.1111/pedi.12816. Epub 2019 Feb 19.


The influence of maternal pregnancy glucose concentrations on associations between a fetal imprinted gene allele score and offspring size at birth.

Petry CJ, Ong KK, Hughes IA, Acerini CL, Dunger DB.

BMC Res Notes. 2018 Nov 19;11(1):821. doi: 10.1186/s13104-018-3933-1.


Associations of vomiting and antiemetic use in pregnancy with levels of circulating GDF15 early in the second trimester: A nested case-control study.

Petry CJ, Ong KK, Burling KA, Barker P, Goodburn SF, Perry JRB, Acerini CL, Hughes IA, Painter RC, Afink GB, Dunger DB, O'Rahilly S.

Wellcome Open Res. 2018 Sep 21;3:123. doi: 10.12688/wellcomeopenres.14818.1. eCollection 2018.


Closed-loop insulin delivery in suboptimally controlled type 1 diabetes: a multicentre, 12-week randomised trial.

Tauschmann M, Thabit H, Bally L, Allen JM, Hartnell S, Wilinska ME, Ruan Y, Sibayan J, Kollman C, Cheng P, Beck RW, Acerini CL, Evans ML, Dunger DB, Elleri D, Campbell F, Bergenstal RM, Criego A, Shah VN, Leelarathna L, Hovorka R; APCam11 Consortium.

Lancet. 2018 Oct 13;392(10155):1321-1329. doi: 10.1016/S0140-6736(18)31947-0. Epub 2018 Oct 3. Erratum in: Lancet. 2018 Oct 13;392(10155):1310.


Targeting glucose control in preterm infants: pilot studies of continuous glucose monitoring.

Thomson L, Elleri D, Bond S, Howlett J, Dunger DB, Beardsall K.

Arch Dis Child Fetal Neonatal Ed. 2019 Jul;104(4):F353-F359. doi: 10.1136/archdischild-2018-314814. Epub 2018 Sep 19.


Reliability and validity of last menstrual period for gestational age estimation in a low-to-middle-income setting.

Macaulay S, Buchmann EJ, Dunger DB, Norris SA.

J Obstet Gynaecol Res. 2019 Jan;45(1):217-225. doi: 10.1111/jog.13801. Epub 2018 Sep 6.


Age at menarche and the future risk of gestational diabetes: a systematic review and dose response meta-analysis.

Petry CJ, Ong KK, Dunger DB.

Acta Diabetol. 2018 Dec;55(12):1209-1219. doi: 10.1007/s00592-018-1214-z. Epub 2018 Aug 29.


Associations between the maternal circulating lipid profile in pregnancy and fetal imprinted gene alleles: a cohort study.

Petry CJ, Koulman A, Lu L, Jenkins B, Furse S, Prentice P, Matthews L, Hughes IA, Acerini CL, Ong KK, Dunger DB.

Reprod Biol Endocrinol. 2018 Aug 29;16(1):82. doi: 10.1186/s12958-018-0399-x.


Renal and Cardiovascular Risk According to Tertiles of Urinary Albumin-to-Creatinine Ratio: The Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial (AdDIT).

Marcovecchio ML, Chiesa ST, Armitage J, Daneman D, Donaghue KC, Jones TW, Mahmud FH, Marshall SM, Neil HAW, Dalton RN, Deanfield J, Dunger DB; Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial (AdDIT) Study Group.

Diabetes Care. 2018 Sep;41(9):1963-1969. doi: 10.2337/dc18-1125. Epub 2018 Jul 19.


Frequent Monitoring of C-Peptide Levels in Newly Diagnosed Type 1 Subjects Using Dried Blood Spots Collected at Home.

Willemsen RH, Burling K, Barker P, Ackland F, Dias RP, Edge J, Smith A, Todd J, Lopez B, Mander AP, Guy C, Dunger DB.

J Clin Endocrinol Metab. 2018 Sep 1;103(9):3350-3358. doi: 10.1210/jc.2018-00500.


The association between age at menarche and later risk of gestational diabetes is mediated by insulin resistance.

Petry CJ, Ong KK, Hughes IA, Acerini CL, Dunger DB.

Acta Diabetol. 2018 Aug;55(8):853-859. doi: 10.1007/s00592-018-1162-7. Epub 2018 May 22.


The effects of gestational diabetes mellitus on fetal growth and neonatal birth measures in an African cohort.

Macaulay S, Munthali RJ, Dunger DB, Norris SA.

Diabet Med. 2018 Oct;35(10):1425-1433. doi: 10.1111/dme.13668. Epub 2018 Jun 1.


Social Determinants of Health Are Associated with Markers of Renal Injury in Adolescents with Type 1 Diabetes.

Cummings LAM, Clarke A, Sochett E, Daneman D, Cherney DZ, Reich HN, Scholey JW, Dunger DB, Mahmud FH.

J Pediatr. 2018 Jul;198:247-253.e1. doi: 10.1016/j.jpeds.2018.03.030. Epub 2018 May 8.


Vomiting in pregnancy is associated with a higher risk of low birth weight: a cohort study.

Petry CJ, Ong KK, Beardsall K, Hughes IA, Acerini CL, Dunger DB.

BMC Pregnancy Childbirth. 2018 May 4;18(1):133. doi: 10.1186/s12884-018-1786-1.


Relationship between islet autoantibody status and the clinical characteristics of children and adults with incident type 1 diabetes in a UK cohort.

Bravis V, Kaur A, Walkey HC, Godsland IF, Misra S, Bingley PJ, Williams AJK, Dunger DB, Dayan CM, Peakman M, Oliver NS, Johnston DG; ADDRESS-2 Management Committee, Patient Advocate Group and Investigators.

BMJ Open. 2018 Apr 4;8(4):e020904. doi: 10.1136/bmjopen-2017-020904.


Serum Phthalate and Triclosan Levels Have Opposing Associations With Risk Factors for Gestational Diabetes Mellitus.

Fisher BG, Frederiksen H, Andersson AM, Juul A, Thankamony A, Ong KK, Dunger DB, Hughes IA, Acerini CL.

Front Endocrinol (Lausanne). 2018 Mar 13;9:99. doi: 10.3389/fendo.2018.00099. eCollection 2018.


Rural-urban variations in age at menarche, adult height, leg-length and abdominal adiposity in black South African women in transitioning South Africa.

Said-Mohamed R, Prioreschi A, Nyati LH, van Heerden A, Munthali RJ, Kahn K, Tollman SM, Gómez-Olivé FX, Houle B, Dunger DB, Norris SA.

Ann Hum Biol. 2018 Mar;45(2):123-132. doi: 10.1080/03014460.2018.1442497. Epub 2018 Mar 20.


The prevalence of gestational diabetes mellitus amongst black South African women is a public health concern.

Macaulay S, Ngobeni M, Dunger DB, Norris SA.

Diabetes Res Clin Pract. 2018 May;139:278-287. doi: 10.1016/j.diabres.2018.03.012. Epub 2018 Mar 8.


Compositional marker in vivo reveals intramyocellular lipid turnover during fasting-induced lipolysis.

Thankamony A, Kemp GJ, Koulman A, Bokii V, Savage DB, Boesch C, Hodson L, Dunger DB, Sleigh A.

Sci Rep. 2018 Feb 9;8(1):2750. doi: 10.1038/s41598-018-21170-x.


ACE Inhibitors and Statins in Adolescents with Type 1 Diabetes.

Dunger DB, Marcovecchio ML, Deanfield J.

N Engl J Med. 2018 Feb 8;378(6):580-581. doi: 10.1056/NEJMc1715763. No abstract available.


The Adolescent Cardio-Renal Intervention Trial (AdDIT): retinal vascular geometry and renal function in adolescents with type 1 diabetes.

Benitez-Aguirre PZ, Wong TY, Craig ME, Davis EA, Cotterill A, Couper JJ, Cameron FJ, Mahmud FH, Jones TW, Hodgson LAB, Dalton RN, Dunger DB, Donaghue KC; Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial (AdDIT).

Diabetologia. 2018 Apr;61(4):968-976. doi: 10.1007/s00125-017-4538-2. Epub 2018 Feb 2.


Associations between bacterial infections and blood pressure in pregnancy.

Petry CJ, Ong KK, Hughes IA, Acerini CL, Dunger DB.

Pregnancy Hypertens. 2017 Oct;10:202-206. doi: 10.1016/j.preghy.2017.09.004. Epub 2017 Sep 12.


Examining the relationships between body image, eating attitudes, BMI, and physical activity in rural and urban South African young adult females using structural equation modeling.

Prioreschi A, Wrottesley SV, Cohen E, Reddy A, Said-Mohamed R, Twine R, Tollman SM, Kahn K, Dunger DB, Norris SA.

PLoS One. 2017 Nov 16;12(11):e0187508. doi: 10.1371/journal.pone.0187508. eCollection 2017.


ACE Inhibitors and Statins in Adolescents with Type 1 Diabetes.

Marcovecchio ML, Chiesa ST, Bond S, Daneman D, Dawson S, Donaghue KC, Jones TW, Mahmud FH, Marshall SM, Neil HAW, Dalton RN, Deanfield J, Dunger DB; AdDIT Study Group.

N Engl J Med. 2017 Nov 2;377(18):1733-1745. doi: 10.1056/NEJMoa1703518.


Neonatal and adult recent thymic emigrants produce IL-8 and express complement receptors CR1 and CR2.

Pekalski ML, García AR, Ferreira RC, Rainbow DB, Smyth DJ, Mashar M, Brady J, Savinykh N, Dopico XC, Mahmood S, Duley S, Stevens HE, Walker NM, Cutler AJ, Waldron-Lynch F, Dunger DB, Shannon-Lowe C, Coles AJ, Jones JL, Wallace C, Todd JA, Wicker LS.

JCI Insight. 2017 Aug 17;2(16). pii: 93739. doi: 10.1172/jci.insight.93739. eCollection 2017 Aug 17.


Relationship between serum inflammatory markers and vascular function in a cohort of adolescents with type 1 diabetes.

Sochett E, Noone D, Grattan M, Slorach C, Moineddin R, Elia Y, Mahmud FH, Dunger DB, Dalton N, Cherney D, Scholey J, Reich H, Deanfield J.

Cytokine. 2017 Nov;99:233-239. doi: 10.1016/j.cyto.2017.07.013. Epub 2017 Jul 29.


Cells with Treg-specific FOXP3 demethylation but low CD25 are prevalent in autoimmunity.

Ferreira RC, Simons HZ, Thompson WS, Rainbow DB, Yang X, Cutler AJ, Oliveira J, Castro Dopico X, Smyth DJ, Savinykh N, Mashar M, Vyse TJ, Dunger DB, Baxendale H, Chandra A, Wallace C, Todd JA, Wicker LS, Pekalski ML.

J Autoimmun. 2017 Nov;84:75-86. doi: 10.1016/j.jaut.2017.07.009. Epub 2017 Jul 23.


The exon3-deleted growth hormone receptor gene polymorphism (d3-GHR) is associated with insulin and spontaneous growth in short SGA children (NESGAS).

Wegmann MG, Thankamony A, Roche E, Hoey H, Kirk J, Shaikh G, Ivarsson SA, Söder O, Dunger DB, Juul A, Jensen RB.

Growth Horm IGF Res. 2017 Aug;35:45-51. doi: 10.1016/j.ghir.2017.07.001. Epub 2017 Jul 12.


Assessing the effectiveness of a 3-month day-and-night home closed-loop control combined with pump suspend feature compared with sensor-augmented pump therapy in youths and adults with suboptimally controlled type 1 diabetes: a randomised parallel study protocol.

Bally L, Thabit H, Tauschmann M, Allen JM, Hartnell S, Wilinska ME, Exall J, Huegel V, Sibayan J, Borgman S, Cheng P, Blackburn M, Lawton J, Elleri D, Leelarathna L, Acerini CL, Campbell F, Shah VN, Criego A, Evans ML, Dunger DB, Kollman C, Bergenstal RM, Hovorka R.

BMJ Open. 2017 Jul 13;7(7):e016738. doi: 10.1136/bmjopen-2017-016738.


Rationale and protocol for the After Diabetes Diagnosis REsearch Support System (ADDRESS): an incident and high risk type 1 diabetes UK cohort study.

Walkey HC, Kaur A, Bravis V, Godsland IF, Misra S, Williams AJK, Bingley PJ, Dunger DB, Oliver N, Johnston DG.

BMJ Open. 2017 Jul 12;7(7):e013956. doi: 10.1136/bmjopen-2016-013956.


Associations between a fetal imprinted gene allele score and late pregnancy maternal glucose concentrations.

Petry CJ, Mooslehner K, Prentice P, Hayes MG, Nodzenski M, Scholtens DM, Hughes IA, Acerini CL, Ong KK, Lowe WL Jr, Dunger DB.

Diabetes Metab. 2017 Sep;43(4):323-331. doi: 10.1016/j.diabet.2017.03.002. Epub 2017 Apr 6.


Early Pregnancy-Associated Plasma Protein A Concentrations Are Associated With Third Trimester Insulin Sensitivity.

Petry CJ, Ong KK, Hughes IA, Acerini CL, Frystyk J, Dunger DB.

J Clin Endocrinol Metab. 2017 Jun 1;102(6):2000-2008. doi: 10.1210/jc.2017-00272.


Clustering of cardio-metabolic risk factors in parents of adolescents with type 1 diabetes and microalbuminuria.

Marcovecchio ML, Tossavainen PH, Owen K, Fullah C, Benitez-Aguirre P, Masi S, Ong K, Nguyen H, Chiesa ST, Dalton RN, Deanfield J, Dunger DB.

Pediatr Diabetes. 2017 Dec;18(8):947-954. doi: 10.1111/pedi.12515. Epub 2017 Mar 8.


Banting Memorial Lecture 2016 Reducing lifetime risk of complications in adolescents with Type 1 diabetes.

Dunger DB.

Diabet Med. 2017 Apr;34(4):460-466. doi: 10.1111/dme.13299. Epub 2017 Jan 17. Review.


Baseline Characteristics and Gender Differences in Prepubertal Children Treated with Growth Hormone in Europe, USA, and Japan: 25 Years' KIGS® Experience (1987-2012) and Review.

Ranke MB, Lindberg A, Tanaka T, Camacho-Hübner C, Dunger DB, Geffner ME.

Horm Res Paediatr. 2017;87(1):30-41. doi: 10.1159/000452887. Epub 2016 Dec 3.


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