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Items: 1 to 50 of 147

1.

Correction: Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria.

Day F, Karaderi T, Jones MR, Meun C, He C, Drong A, Kraft P, Lin N, Huang H, Broer L, Magi R, Saxena R, Laisk T, Urbanek M, Hayes MG, Thorleifsson G, Fernandez-Tajes J, Mahajan A, Mullin BH, Stuckey BGA, Spector TD, Wilson SG, Goodarzi MO, Davis L, Obermayer-Pietsch B, Uitterlinden AG, Anttila V, Neale BM, Jarvelin MR, Fauser B, Kowalska I, Visser JA, Andersen M, Ong K, Stener-Victorin E, Ehrmann D, Legro RS, Salumets A, McCarthy MI, Morin-Papunen L, Thorsteinsdottir U, Stefansson K; 23andMe Research Team, Styrkarsdottir U, Perry JRB, Dunaif A, Laven J, Franks S, Lindgren CM, Welt CK.

PLoS Genet. 2019 Dec 5;15(12):e1008517. doi: 10.1371/journal.pgen.1008517. eCollection 2019 Dec.

2.

Hyperandrogenemia is Common in Asymptomatic Women and is Associated with Increased Metabolic Risk.

Torchen LC, Tsai JN, Jasti P, Macaya R, Sisk R, Dapas ML, Hayes MG, Urbanek M, Dunaif A.

Obesity (Silver Spring). 2019 Nov 14. doi: 10.1002/oby.22659. [Epub ahead of print]

PMID:
31729166
3.

Family-based quantitative trait meta-analysis implicates rare noncoding variants in DENND1A in polycystic ovary syndrome.

Dapas M, Sisk R, Legro RS, Urbanek M, Dunaif A, Hayes MG.

J Clin Endocrinol Metab. 2019 Apr 30. pii: jc.2018-02496. doi: 10.1210/jc.2018-02496. [Epub ahead of print]

PMID:
31038695
4.

Distinctive Reproductive Phenotypes in Peripubertal Girls at Risk for Polycystic Ovary Syndrome.

Torchen LC, Legro RS, Dunaif A.

J Clin Endocrinol Metab. 2019 Aug 1;104(8):3355-3361. doi: 10.1210/jc.2018-02313.

PMID:
30844044
5.

Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria.

Day F, Karaderi T, Jones MR, Meun C, He C, Drong A, Kraft P, Lin N, Huang H, Broer L, Magi R, Saxena R, Laisk T, Urbanek M, Hayes MG, Thorleifsson G, Fernandez-Tajes J, Mahajan A, Mullin BH, Stuckey BGA, Spector TD, Wilson SG, Goodarzi MO, Davis L, Obermayer-Pietsch B, Uitterlinden AG, Anttila V, Neale BM, Jarvelin MR, Fauser B, Kowalska I, Visser JA, Andersen M, Ong K, Stener-Victorin E, Ehrmann D, Legro RS, Salumets A, McCarthy MI, Morin-Papunen L, Thorsteinsdottir U, Stefansson K; 23andMe Research Team, Styrkarsdottir U, Perry JRB, Dunaif A, Laven J, Franks S, Lindgren CM, Welt CK.

PLoS Genet. 2018 Dec 19;14(12):e1007813. doi: 10.1371/journal.pgen.1007813. eCollection 2018 Dec. Erratum in: PLoS Genet. 2019 Dec 5;15(12):e1008517.

6.

Corrigendum to "Long non-coding RNA LINC-01572:28 inhibits granulosa cell growth via a decrease in p27 (Kip1) degradation in patients with polycystic ovary syndrome" [EBioMedicine 36 (2018) 526-538].

Zhao J, Xu J, Wang W, Zhao H, Liu H, Liu X, Liu J, Sun Y, Dunaif A, Du Y, Chen ZJ.

EBioMedicine. 2018 Nov;37:563. doi: 10.1016/j.ebiom.2018.10.050. Epub 2018 Oct 28. No abstract available.

7.

Long non-coding RNA LINC-01572:28 inhibits granulosa cell growth via a decrease in p27 (Kip1) degradation in patients with polycystic ovary syndrome.

Zhao J, Xu J, Wang W, Zhao H, Liu H, Liu X, Liu J, Sun Y, Dunaif A, Du Y, Chen ZJ.

EBioMedicine. 2018 Oct;36:526-538. doi: 10.1016/j.ebiom.2018.09.043. Epub 2018 Oct 5. Erratum in: EBioMedicine. 2018 Nov;37:563.

8.

The HMGA2-IMP2 Pathway Promotes Granulosa Cell Proliferation in Polycystic Ovary Syndrome.

Li M, Zhao H, Zhao SG, Wei DM, Zhao YR, Huang T, Muhammad T, Yan L, Gao F, Li L, Lu G, Chan WY, Leung PCK, Dunaif A, Liu HB, Chen ZJ.

J Clin Endocrinol Metab. 2019 Apr 1;104(4):1049-1059. doi: 10.1210/jc.2018-00544.

9.

Exaggerated glucagon responses to hypoglycemia in women with polycystic ovary syndrome.

Sam S, Vellanki P, Yalamanchi SK, Bergman RN, Dunaif A.

Metabolism. 2017 Jun;71:125-131. doi: 10.1016/j.metabol.2017.03.008. Epub 2017 Mar 22.

10.

Pathogenic Anti-Müllerian Hormone Variants in Polycystic Ovary Syndrome.

Gorsic LK, Kosova G, Werstein B, Sisk R, Legro RS, Hayes MG, Teixeira JM, Dunaif A, Urbanek M.

J Clin Endocrinol Metab. 2017 Aug 1;102(8):2862-2872. doi: 10.1210/jc.2017-00612.

11.

Delayed Diagnosis and a Lack of Information Associated With Dissatisfaction in Women With Polycystic Ovary Syndrome.

Gibson-Helm M, Teede H, Dunaif A, Dokras A.

J Clin Endocrinol Metab. 2017 Feb 1;102(2):604-612. doi: 10.1210/jc.2016-2963.

12.

An Exercise Intervention for South Asian Mothers with Risk Factors for Diabetes.

Kandula NR, Dave S, De Chavez PJ, Marquez DX, Bharucha H, Mammen S, Dunaif A, Ackermann RT, Kumar S, Siddique J.

Transl J Am Coll Sports Med. 2016 Jun 15;1(6):52-59.

13.

Polycystic ovary syndrome.

Azziz R, Carmina E, Chen Z, Dunaif A, Laven JS, Legro RS, Lizneva D, Natterson-Horowtiz B, Teede HJ, Yildiz BO.

Nat Rev Dis Primers. 2016 Aug 11;2:16057. doi: 10.1038/nrdp.2016.57. Review.

PMID:
27510637
14.

Geospatial Resolution of Human and Bacterial Diversity with City-Scale Metagenomics.

Afshinnekoo E, Meydan C, Chowdhury S, Jaroudi D, Boyer C, Bernstein N, Maritz JM, Reeves D, Gandara J, Chhangawala S, Ahsanuddin S, Simmons A, Nessel T, Sundaresh B, Pereira E, Jorgensen E, Kolokotronis SO, Kirchberger N, Garcia I, Gandara D, Dhanraj S, Nawrin T, Saletore Y, Alexander N, Vijay P, Hénaff EM, Zumbo P, Walsh M, O'Mullan GD, Tighe S, Dudley JT, Dunaif A, Ennis S, O'Halloran E, Magalhaes TR, Boone B, Jones AL, Muth TR, Paolantonio KS, Alter E, Schadt EE, Garbarino J, Prill RJ, Carlton JM, Levy S, Mason CE.

Cell Syst. 2015 Jul 29;1(1):97-97.e3. doi: 10.1016/j.cels.2015.07.006. Epub 2015 Jul 29. No abstract available.

15.

Modern Methods for Delineating Metagenomic Complexity.

Afshinnekoo E, Meydan C, Chowdhury S, Jaroudi D, Boyer C, Bernstein N, Maritz JM, Reeves D, Gandara J, Chhangawala S, Ahsanuddin S, Simmons A, Nessel T, Sundaresh B, Pereira E, Jorgensen E, Kolokotronis SO, Kirchberger N, Garcia I, Gandara D, Dhanraj S, Nawrin T, Saletore Y, Alexander N, Vijay P, Hénaff EM, Zumbo P, Walsh M, O'Mullan GD, Tighe S, Dudley JT, Dunaif A, Ennis S, O'Halloran E, Magalhaes TR, Boone B, Jones AL, Muth TR, Paolantonio KS, Alter E, Schadt EE, Garbarino J, Prill RJ, Carlton JM, Levy S, Mason CE.

Cell Syst. 2015 Jul 29;1(1):6-7. doi: 10.1016/j.cels.2015.07.007. Epub 2015 Jul 29. No abstract available.

16.

Increased antimüllerian hormone levels and other reproductive endocrine changes in adult male relatives of women with polycystic ovary syndrome.

Torchen LC, Kumar A, Kalra B, Savjani G, Sisk R, Legro RS, Dunaif A.

Fertil Steril. 2016 Jul;106(1):50-55. doi: 10.1016/j.fertnstert.2016.03.029. Epub 2016 Apr 1.

17.

Evidence for Increased 5α-Reductase Activity During Early Childhood in Daughters of Women With Polycystic Ovary Syndrome.

Torchen LC, Idkowiak J, Fogel NR, O'Neil DM, Shackleton CH, Arlt W, Dunaif A.

J Clin Endocrinol Metab. 2016 May;101(5):2069-75. doi: 10.1210/jc.2015-3926. Epub 2016 Mar 18.

18.

Perspectives in Polycystic Ovary Syndrome: From Hair to Eternity.

Dunaif A.

J Clin Endocrinol Metab. 2016 Mar;101(3):759-68. doi: 10.1210/jc.2015-3780. Epub 2016 Feb 23.

19.

Corrigendum: Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations.

Hayes MG, Urbanek M, Ehrmann DA, Armstrong LL, Lee JY, Sisk R, Karaderi T, Barber TM, McCarthy MI, Franks S, Lindgren CM, Welt CK, Diamanti-Kandarakis E, Panidis D, Goodarzi MO, Azziz R, Zhang Y, James RG, Olivier M, Kissebah AH; Reproductive Medicine Network, Stener-Victorin E, Legro RS, Dunaif A.

Nat Commun. 2016 Feb 12;7:10762. doi: 10.1038/ncomms10762. No abstract available.

20.

Geospatial Resolution of Human and Bacterial Diversity with City-Scale Metagenomics.

Afshinnekoo E, Meydan C, Chowdhury S, Jaroudi D, Boyer C, Bernstein N, Maritz JM, Reeves D, Gandara J, Chhangawala S, Ahsanuddin S, Simmons A, Nessel T, Sundaresh B, Pereira E, Jorgensen E, Kolokotronis SO, Kirchberger N, Garcia I, Gandara D, Dhanraj S, Nawrin T, Saletore Y, Alexander N, Vijay P, Hénaff EM, Zumbo P, Walsh M, O'Mullan GD, Tighe S, Dudley JT, Dunaif A, Ennis S, O'Halloran E, Magalhaes TR, Boone B, Jones AL, Muth TR, Paolantonio KS, Alter E, Schadt EE, Garbarino J, Prill RJ, Carlton JM, Levy S, Mason CE.

Cell Syst. 2015 Jul 29;1(1):72-87. Epub 2015 Mar 3.

21.

Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations.

Hayes MG, Urbanek M, Ehrmann DA, Armstrong LL, Lee JY, Sisk R, Karaderi T, Barber TM, McCarthy MI, Franks S, Lindgren CM, Welt CK, Diamanti-Kandarakis E, Panidis D, Goodarzi MO, Azziz R, Zhang Y, James RG, Olivier M, Kissebah AH; Reproductive Medicine Network, Stener-Victorin E, Legro RS, Dunaif A.

Nat Commun. 2015 Aug 18;6:7502. doi: 10.1038/ncomms8502. Erratum in: Nat Commun. 2016;7:10762.

22.

Evidence for gonadotrophin secretory and steroidogenic abnormalities in brothers of women with polycystic ovary syndrome.

Liu DM, Torchen LC, Sung Y, Paparodis R, Legro RS, Grebe SK, Singh RJ, Taylor RL, Dunaif A.

Hum Reprod. 2014 Dec;29(12):2764-72. doi: 10.1093/humrep/deu282. Epub 2014 Oct 21.

23.

Persistent apparent pancreatic β-cell defects in premenarchal PCOS relatives.

Torchen LC, Fogel NR, Brickman WJ, Paparodis R, Dunaif A.

J Clin Endocrinol Metab. 2014 Oct;99(10):3855-62. doi: 10.1210/jc.2014-1474. Epub 2014 Jul 16.

24.

Parent-of-origin effects on glucose homeostasis in polycystic ovary syndrome.

Kobaly K, Vellanki P, Sisk RK, Armstrong L, Lee JY, Lee J, Hayes MG, Urbanek M, Legro RS, Dunaif A.

J Clin Endocrinol Metab. 2014 Aug;99(8):2961-6. doi: 10.1210/jc.2013-4338. Epub 2014 May 30.

25.

The inflammatory gene pathway is not a major contributor to polycystic ovary snydrome.

Bhatt S, Mutharasan P, Garcia OA, Jafari N, Legro RS, Dunaif A, Urbanek M.

J Clin Endocrinol Metab. 2014 Mar;99(3):E567-71. doi: 10.1210/jc.2013-2342. Epub 2014 Jan 1.

26.

Renaming PCOS--a two-state solution.

Dunaif A, Fauser BC.

J Clin Endocrinol Metab. 2013 Nov;98(11):4325-8. doi: 10.1210/jc.2013-2040. Epub 2013 Sep 5.

27.

Familial aggregation of circulating C-reactive protein in polycystic ovary syndrome.

Sasidevi A, Vellanki P, Kunselman AR, Raja-Khan N, Dunaif A, Legro RS.

Hum Reprod. 2013 Mar;28(3):770-6. doi: 10.1093/humrep/des416. Epub 2012 Dec 20.

28.

Evidence for chromosome 2p16.3 polycystic ovary syndrome susceptibility locus in affected women of European ancestry.

Mutharasan P, Galdones E, Peñalver Bernabé B, Garcia OA, Jafari N, Shea LD, Woodruff TK, Legro RS, Dunaif A, Urbanek M.

J Clin Endocrinol Metab. 2013 Jan;98(1):E185-90. doi: 10.1210/jc.2012-2471. Epub 2012 Nov 1.

29.

Insulin resistance and the polycystic ovary syndrome revisited: an update on mechanisms and implications.

Diamanti-Kandarakis E, Dunaif A.

Endocr Rev. 2012 Dec;33(6):981-1030. doi: 10.1210/er.2011-1034. Epub 2012 Oct 12. Review.

30.

Negative association of acetate with visceral adipose tissue and insulin levels.

Layden BT, Yalamanchi SK, Wolever TM, Dunaif A, Lowe WL Jr.

Diabetes Metab Syndr Obes. 2012;5:49-55. doi: 10.2147/DMSO.S29244. Epub 2012 Feb 28.

31.

Association of fibrillin-3 and transcription factor-7-like 2 gene variants with metabolic phenotypes in PCOS.

Yalamanchi SK, Sam S, Cardenas MO, Holaday LW, Urbanek M, Dunaif A.

Obesity (Silver Spring). 2012 Jun;20(6):1273-8. doi: 10.1038/oby.2011.400. Epub 2012 Feb 2.

32.

Should all women with PCOS be treated for insulin resistance?

Marshall JC, Dunaif A.

Fertil Steril. 2012 Jan;97(1):18-22. doi: 10.1016/j.fertnstert.2011.11.036.

33.

Polycystic ovary syndrome in 2011: Genes, aging and sleep apnea in polycystic ovary syndrome.

Dunaif A.

Nat Rev Endocrinol. 2011 Dec 20;8(2):72-4. doi: 10.1038/nrendo.2011.227. Review.

PMID:
22183129
34.

Replication of association of DENND1A and THADA variants with polycystic ovary syndrome in European cohorts.

Goodarzi MO, Jones MR, Li X, Chua AK, Garcia OA, Chen YD, Krauss RM, Rotter JI, Ankener W, Legro RS, Azziz R, Strauss JF 3rd, Dunaif A, Urbanek M.

J Med Genet. 2012 Feb;49(2):90-5. doi: 10.1136/jmedgenet-2011-100427. Epub 2011 Dec 17.

35.

Catechol-O-methyltransferase (COMT) single nucleotide polymorphisms and haplotypes are not major risk factors for polycystic ovary syndrome.

Hill LD, Ewens KG, Maher BS, York TP, Legro RS, Dunaif A, Strauss JF 3rd.

Mol Cell Endocrinol. 2012 Mar 5;350(1):72-7. doi: 10.1016/j.mce.2011.11.022. Epub 2011 Dec 8.

36.

Consensus on women's health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group.

Fauser BC, Tarlatzis BC, Rebar RW, Legro RS, Balen AH, Lobo R, Carmina E, Chang J, Yildiz BO, Laven JS, Boivin J, Petraglia F, Wijeyeratne CN, Norman RJ, Dunaif A, Franks S, Wild RA, Dumesic D, Barnhart K.

Fertil Steril. 2012 Jan;97(1):28-38.e25. doi: 10.1016/j.fertnstert.2011.09.024. Epub 2011 Dec 6.

PMID:
22153789
37.

The Hirsute woman: challenges in evaluation and management.

Paparodis R, Dunaif A.

Endocr Pract. 2011 Sep-Oct;17(5):807-18. doi: 10.4158/EP11117.RA. Review.

PMID:
21856600
38.

Ovarian hypertension: polycystic ovary syndrome.

Bentley-Lewis R, Seely E, Dunaif A.

Endocrinol Metab Clin North Am. 2011 Jun;40(2):433-49, ix-x. doi: 10.1016/j.ecl.2011.01.009.

39.

Evidence for increased cardiovascular events in the fathers but not mothers of women with polycystic ovary syndrome.

Taylor MC, Reema Kar A, Kunselman AR, Stetter CM, Dunaif A, Legro RS.

Hum Reprod. 2011 Aug;26(8):2226-31. doi: 10.1093/humrep/der101. Epub 2011 Apr 19.

40.

Type 2 diabetes susceptibility single-nucleotide polymorphisms are not associated with polycystic ovary syndrome.

Ewens KG, Jones MR, Ankener W, Stewart DR, Urbanek M, Dunaif A, Legro RS, Chua A, Azziz R, Spielman RS, Goodarzi MO, Strauss JF 3rd.

Fertil Steril. 2011 Jun 30;95(8):2538-41.e1-6. doi: 10.1016/j.fertnstert.2011.02.050. Epub 2011 Mar 27.

41.

FTO and MC4R gene variants are associated with obesity in polycystic ovary syndrome.

Ewens KG, Jones MR, Ankener W, Stewart DR, Urbanek M, Dunaif A, Legro RS, Chua A, Azziz R, Spielman RS, Goodarzi MO, Strauss JF 3rd.

PLoS One. 2011 Jan 20;6(1):e16390. doi: 10.1371/journal.pone.0016390.

42.

Polymorphisms in the SHBG gene influence serum SHBG levels in women with polycystic ovary syndrome.

Wickham EP 3rd, Ewens KG, Legro RS, Dunaif A, Nestler JE, Strauss JF 3rd.

J Clin Endocrinol Metab. 2011 Apr;96(4):E719-27. doi: 10.1210/jc.2010-1842. Epub 2011 Jan 20.

43.

Genetic rescue of nonclassical ERα signaling normalizes energy balance in obese Erα-null mutant mice.

Park CJ, Zhao Z, Glidewell-Kenney C, Lazic M, Chambon P, Krust A, Weiss J, Clegg DJ, Dunaif A, Jameson JL, Levine JE.

J Clin Invest. 2011 Feb;121(2):604-12. doi: 10.1172/JCI41702. Epub 2011 Jan 18.

44.

Prenatal androgen treatment alters body composition and glucose homeostasis in male rats.

Lazic M, Aird F, Levine JE, Dunaif A.

J Endocrinol. 2011 Mar;208(3):293-300. doi: 10.1677/JOE-10-0263. Epub 2010 Dec 20.

45.

Experimentally induced gestational androgen excess disrupts glucoregulation in rhesus monkey dams and their female offspring.

Abbott DH, Bruns CR, Barnett DK, Dunaif A, Goodfriend TL, Dumesic DA, Tarantal AF.

Am J Physiol Endocrinol Metab. 2010 Nov;299(5):E741-51. doi: 10.1152/ajpendo.00058.2010. Epub 2010 Aug 3.

46.

Infants of women with polycystic ovary syndrome have lower cord blood androstenedione and estradiol levels.

Anderson H, Fogel N, Grebe SK, Singh RJ, Taylor RL, Dunaif A.

J Clin Endocrinol Metab. 2010 May;95(5):2180-6. doi: 10.1210/jc.2009-2651. Epub 2010 Mar 12.

47.

Family-based analysis of candidate genes for polycystic ovary syndrome.

Ewens KG, Stewart DR, Ankener W, Urbanek M, McAllister JM, Chen C, Baig KM, Parker SC, Margulies EH, Legro RS, Dunaif A, Strauss JF 3rd, Spielman RS.

J Clin Endocrinol Metab. 2010 May;95(5):2306-15. doi: 10.1210/jc.2009-2703. Epub 2010 Mar 3.

48.

Associations of birthweight and gestational age with reproductive and metabolic phenotypes in women with polycystic ovarian syndrome and their first-degree relatives.

Legro RS, Roller RL, Dodson WC, Stetter CM, Kunselman AR, Dunaif A.

J Clin Endocrinol Metab. 2010 Feb;95(2):789-99. doi: 10.1210/jc.2009-1849. Epub 2009 Dec 4.

49.

High prevalence of metabolic syndrome in first-degree male relatives of women with polycystic ovary syndrome is related to high rates of obesity.

Coviello AD, Sam S, Legro RS, Dunaif A.

J Clin Endocrinol Metab. 2009 Nov;94(11):4361-6. doi: 10.1210/jc.2009-1333. Epub 2009 Oct 16.

50.

PDE8A genetic variation, polycystic ovary syndrome and androgen levels in women.

Chen C, Wickenheisser J, Ewens KG, Ankener W, Legro RS, Dunaif A, McAllister JM, Spielman RS, Strauss JF 3rd.

Mol Hum Reprod. 2009 Aug;15(8):459-69. doi: 10.1093/molehr/gap035. Epub 2009 May 29.

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