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Items: 27

1.

Poor sleep quality is associated with exercise limitation in precapillary pulmonary hypertension.

Tiede H, Rorzyczka J, Dumitrascu R, Belly M, Reichenberger F, Ghofrani HA, Seeger W, Heitmann J, Schulz R.

BMC Pulm Med. 2015 Feb 13;15:11. doi: 10.1186/s12890-015-0005-3.

2.

Arterial hypertension in a murine model of sleep apnea: role of NADPH oxidase 2.

Schulz R, Murzabekova G, Egemnazarov B, Kraut S, Eisele HJ, Dumitrascu R, Heitmann J, Seimetz M, Witzenrath M, Ghofrani HA, Schermuly RT, Grimminger F, Seeger W, Weissmann N.

J Hypertens. 2014 Feb;32(2):300-5. doi: 10.1097/HJH.0000000000000016.

PMID:
24270180
3.

Obstructive sleep apnea, oxidative stress and cardiovascular disease: lessons from animal studies.

Dumitrascu R, Heitmann J, Seeger W, Weissmann N, Schulz R.

Oxid Med Cell Longev. 2013;2013:234631. doi: 10.1155/2013/234631. Epub 2013 Mar 3. Review.

4.

Sleep apnea in precapillary pulmonary hypertension.

Dumitrascu R, Tiede H, Eckermann J, Mayer K, Reichenberger F, Ghofrani HA, Seeger W, Heitmann J, Schulz R.

Sleep Med. 2013 Mar;14(3):247-51. doi: 10.1016/j.sleep.2012.11.013. Epub 2013 Jan 20.

PMID:
23340085
5.

[Obstructive sleep apnea and stroke].

Dumitrascu R, Tiede H, Rosengarten B, Schulz R.

Pneumologie. 2012 Aug;66(8):476-9. doi: 10.1055/s-0032-1309966. Epub 2012 Aug 8. German.

6.

Quality of life in clinically stable adult cystic fibrosis out-patients: associations with daytime sleepiness and sleep quality.

Bouka A, Tiede H, Liebich L, Dumitrascu R, Hecker C, Reichenberger F, Mayer K, Seeger W, Schulz R.

Respir Med. 2012 Sep;106(9):1244-9. doi: 10.1016/j.rmed.2012.06.010. Epub 2012 Jul 6.

7.

Sleep-disordered breathing in deep vein thrombosis and acute pulmonary embolism.

Arzt M, Luigart R, Schum C, Lüthje L, Stein A, Koper I, Hecker C, Dumitrascu R, Schulz R; "Circulation and Sleep" working group of the German Society of Sleep Research and Sleep Medicine (DGSM).

Eur Respir J. 2012 Oct;40(4):919-24. Epub 2012 Feb 23.

8.

Inducible NOS inhibition reverses tobacco-smoke-induced emphysema and pulmonary hypertension in mice.

Seimetz M, Parajuli N, Pichl A, Veit F, Kwapiszewska G, Weisel FC, Milger K, Egemnazarov B, Turowska A, Fuchs B, Nikam S, Roth M, Sydykov A, Medebach T, Klepetko W, Jaksch P, Dumitrascu R, Garn H, Voswinckel R, Kostin S, Seeger W, Schermuly RT, Grimminger F, Ghofrani HA, Weissmann N.

Cell. 2011 Oct 14;147(2):293-305. doi: 10.1016/j.cell.2011.08.035.

9.

The role of dimethylarginine dimethylaminohydrolase in idiopathic pulmonary fibrosis.

Pullamsetti SS, Savai R, Dumitrascu R, Dahal BK, Wilhelm J, Konigshoff M, Zakrzewicz D, Ghofrani HA, Weissmann N, Eickelberg O, Guenther A, Leiper J, Seeger W, Grimminger F, Schermuly RT.

Sci Transl Med. 2011 Jun 15;3(87):87ra53. doi: 10.1126/scitranslmed.3001725.

10.

Terguride ameliorates monocrotaline-induced pulmonary hypertension in rats.

Dumitrascu R, Kulcke C, Königshoff M, Kouri F, Yang X, Morrell N, Ghofrani HA, Weissmann N, Reiter R, Seeger W, Grimminger F, Eickelberg O, Schermuly RT, Pullamsetti SS.

Eur Respir J. 2011 May;37(5):1104-18. doi: 10.1183/09031936.00126010. Epub 2010 Oct 14.

11.

Activation of the WNT/β-catenin pathway attenuates experimental emphysema.

Kneidinger N, Yildirim AÖ, Callegari J, Takenaka S, Stein MM, Dumitrascu R, Bohla A, Bracke KR, Morty RE, Brusselle GG, Schermuly RT, Eickelberg O, Königshoff M.

Am J Respir Crit Care Med. 2011 Mar 15;183(6):723-33. doi: 10.1164/rccm.200910-1560OC. Epub 2010 Oct 1.

PMID:
20889911
12.

Increased expression of 5-hydroxytryptamine2A/B receptors in idiopathic pulmonary fibrosis: a rationale for therapeutic intervention.

Königshoff M, Dumitrascu R, Udalov S, Amarie OV, Reiter R, Grimminger F, Seeger W, Schermuly RT, Eickelberg O.

Thorax. 2010 Nov;65(11):949-55. doi: 10.1136/thx.2009.134353. Epub 2010 Jul 29.

PMID:
20671305
13.

Treprostinil inhibits the recruitment of bone marrow-derived circulating fibrocytes in chronic hypoxic pulmonary hypertension.

Nikam VS, Schermuly RT, Dumitrascu R, Weissmann N, Kwapiszewska G, Morrell N, Klepetko W, Fink L, Seeger W, Voswinckel R.

Eur Respir J. 2010 Dec;36(6):1302-14. doi: 10.1183/09031936.00028009. Epub 2010 Jun 4.

14.

Effects of phosphodiesterase 4 inhibition on bleomycin-induced pulmonary fibrosis in mice.

Udalov S, Dumitrascu R, Pullamsetti SS, Al-tamari HM, Weissmann N, Ghofrani HA, Guenther A, Voswinckel R, Seeger W, Grimminger F, Schermuly RT.

BMC Pulm Med. 2010 May 5;10:26. doi: 10.1186/1471-2466-10-26.

15.

Inactivation of sestrin 2 induces TGF-beta signaling and partially rescues pulmonary emphysema in a mouse model of COPD.

Wempe F, De-Zolt S, Koli K, Bangsow T, Parajuli N, Dumitrascu R, Sterner-Kock A, Weissmann N, Keski-Oja J, von Melchner H.

Dis Model Mech. 2010 Mar-Apr;3(3-4):246-53. doi: 10.1242/dmm.004234. Epub 2010 Jan 27.

16.

Role of epidermal growth factor inhibition in experimental pulmonary hypertension.

Dahal BK, Cornitescu T, Tretyn A, Pullamsetti SS, Kosanovic D, Dumitrascu R, Ghofrani HA, Weissmann N, Voswinckel R, Banat GA, Seeger W, Grimminger F, Schermuly RT.

Am J Respir Crit Care Med. 2010 Jan 15;181(2):158-67. doi: 10.1164/rccm.200811-1682OC. Epub 2009 Oct 22.

PMID:
19850946
17.

The soluble guanylate cyclase activator HMR1766 reverses hypoxia-induced experimental pulmonary hypertension in mice.

Weissmann N, Hackemack S, Dahal BK, Pullamsetti SS, Savai R, Mittal M, Fuchs B, Medebach T, Dumitrascu R, Eickels Mv, Ghofrani HA, Seeger W, Grimminger F, Schermuly RT.

Am J Physiol Lung Cell Mol Physiol. 2009 Oct;297(4):L658-65. doi: 10.1152/ajplung.00189.2009. Epub 2009 Jul 17.

18.

Evaluation of angiogenesis using micro-computed tomography in a xenograft mouse model of lung cancer.

Savai R, Langheinrich AC, Schermuly RT, Pullamsetti SS, Dumitrascu R, Traupe H, Rau WS, Seeger W, Grimminger F, Banat GA.

Neoplasia. 2009 Jan;11(1):48-56.

19.

Characterization of a murine model of monocrotaline pyrrole-induced acute lung injury.

Dumitrascu R, Koebrich S, Dony E, Weissmann N, Savai R, Pullamsetti SS, Ghofrani HA, Samidurai A, Traupe H, Seeger W, Grimminger F, Schermuly RT.

BMC Pulm Med. 2008 Dec 17;8:25. doi: 10.1186/1471-2466-8-25.

20.

Effects of cell-penetrating peptides and pegylation on transfection efficiency of polyethylenimine in mouse lungs.

Nguyen J, Xie X, Neu M, Dumitrascu R, Reul R, Sitterberg J, Bakowsky U, Schermuly R, Fink L, Schmehl T, Gessler T, Seeger W, Kissel T.

J Gene Med. 2008 Nov;10(11):1236-46. doi: 10.1002/jgm.1255.

PMID:
18780309
21.

Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension.

Schermuly RT, Stasch JP, Pullamsetti SS, Middendorff R, Müller D, Schlüter KD, Dingendorf A, Hackemack S, Kolosionek E, Kaulen C, Dumitrascu R, Weissmann N, Mittendorf J, Klepetko W, Seeger W, Ghofrani HA, Grimminger F.

Eur Respir J. 2008 Oct;32(4):881-91. doi: 10.1183/09031936.00114407. Epub 2008 Jun 11.

22.

Partial reversal of experimental pulmonary hypertension by phosphodiesterase-3/4 inhibition.

Dony E, Lai YJ, Dumitrascu R, Pullamsetti SS, Savai R, Ghofrani HA, Weissmann N, Schudt C, Flockerzi D, Seeger W, Grimminger F, Schermuly RT.

Eur Respir J. 2008 Mar;31(3):599-610. Epub 2007 Nov 21.

23.

Phosphodiesterase 1 upregulation in pulmonary arterial hypertension: target for reverse-remodeling therapy.

Schermuly RT, Pullamsetti SS, Kwapiszewska G, Dumitrascu R, Tian X, Weissmann N, Ghofrani HA, Kaulen C, Dunkern T, Schudt C, Voswinckel R, Zhou J, Samidurai A, Klepetko W, Paddenberg R, Kummer W, Seeger W, Grimminger F.

Circulation. 2007 May 1;115(17):2331-9. Epub 2007 Apr 16.

PMID:
17438150
24.

Dysregulated bone morphogenetic protein signaling in monocrotaline-induced pulmonary arterial hypertension.

Morty RE, Nejman B, Kwapiszewska G, Hecker M, Zakrzewicz A, Kouri FM, Peters DM, Dumitrascu R, Seeger W, Knaus P, Schermuly RT, Eickelberg O.

Arterioscler Thromb Vasc Biol. 2007 May;27(5):1072-8. Epub 2007 Mar 8.

PMID:
17347486
25.

Classical transient receptor potential channel 6 (TRPC6) is essential for hypoxic pulmonary vasoconstriction and alveolar gas exchange.

Weissmann N, Dietrich A, Fuchs B, Kalwa H, Ay M, Dumitrascu R, Olschewski A, Storch U, Mederos y Schnitzler M, Ghofrani HA, Schermuly RT, Pinkenburg O, Seeger W, Grimminger F, Gudermann T.

Proc Natl Acad Sci U S A. 2006 Dec 12;103(50):19093-8. Epub 2006 Dec 1.

26.

Activation of soluble guanylate cyclase reverses experimental pulmonary hypertension and vascular remodeling.

Dumitrascu R, Weissmann N, Ghofrani HA, Dony E, Beuerlein K, Schmidt H, Stasch JP, Gnoth MJ, Seeger W, Grimminger F, Schermuly RT.

Circulation. 2006 Jan 17;113(2):286-95. Epub 2006 Jan 3.

PMID:
16391154
27.

Inhaled iloprost reverses vascular remodeling in chronic experimental pulmonary hypertension.

Schermuly RT, Yilmaz H, Ghofrani HA, Woyda K, Pullamsetti S, Schulz A, Gessler T, Dumitrascu R, Weissmann N, Grimminger F, Seeger W.

Am J Respir Crit Care Med. 2005 Aug 1;172(3):358-63. Epub 2005 May 5.

PMID:
15879421

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