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Items: 1 to 50 of 85

1.

Type IV Pili as a Therapeutic Target.

Duménil G.

Trends Microbiol. 2019 Aug;27(8):658-661. doi: 10.1016/j.tim.2019.05.005. Epub 2019 Jun 7.

PMID:
31182345
2.

Inhibitors of the Neisseria meningitidis PilF ATPase provoke type IV pilus disassembly.

Aubey F, Corre JP, Kong Y, Xu X, Obino D, Goussard S, Lapeyrere C, Souphron J, Couturier C, Renard S, Duménil G.

Proc Natl Acad Sci U S A. 2019 Apr 23;116(17):8481-8486. doi: 10.1073/pnas.1817757116. Epub 2019 Apr 4.

PMID:
30948644
3.

The Many Faces of Bacterium-Endothelium Interactions during Systemic Infections.

Obino D, Duménil G.

Microbiol Spectr. 2019 Mar;7(2). doi: 10.1128/microbiolspec.BAI-0010-2019. Review.

PMID:
30848239
4.

Adhesion to nanofibers drives cell membrane remodeling through one-dimensional wetting.

Charles-Orszag A, Tsai FC, Bonazzi D, Manriquez V, Sachse M, Mallet A, Salles A, Melican K, Staneva R, Bertin A, Millien C, Goussard S, Lafaye P, Shorte S, Piel M, Krijnse-Locker J, Brochard-Wyart F, Bassereau P, Duménil G.

Nat Commun. 2018 Oct 25;9(1):4450. doi: 10.1038/s41467-018-06948-x.

5.

Intermittent Pili-Mediated Forces Fluidize Neisseria meningitidis Aggregates Promoting Vascular Colonization.

Bonazzi D, Lo Schiavo V, Machata S, Djafer-Cherif I, Nivoit P, Manriquez V, Tanimoto H, Husson J, Henry N, Chaté H, Voituriez R, Duménil G.

Cell. 2018 Jun 28;174(1):143-155.e16. doi: 10.1016/j.cell.2018.04.010. Epub 2018 May 17.

6.

Microbial pathogenesis meets biomechanics.

Charles-Orszag A, Lemichez E, Tran Van Nhieu G, Duménil G.

Curr Opin Cell Biol. 2016 Feb;38:31-7. doi: 10.1016/j.ceb.2016.01.005. Epub 2016 Feb 2. Review.

PMID:
26849533
7.

Neisseria meningitidis Type IV Pili Composed of Sequence Invariable Pilins Are Masked by Multisite Glycosylation.

Gault J, Ferber M, Machata S, Imhaus AF, Malosse C, Charles-Orszag A, Millien C, Bouvier G, Bardiaux B, Péhau-Arnaudet G, Klinge K, Podglajen I, Ploy MC, Seifert HS, Nilges M, Chamot-Rooke J, Duménil G.

PLoS Pathog. 2015 Sep 14;11(9):e1005162. doi: 10.1371/journal.ppat.1005162. eCollection 2015 Sep.

8.

The number of Neisseria meningitidis type IV pili determines host cell interaction.

Imhaus AF, Duménil G.

EMBO J. 2014 Aug 18;33(16):1767-83. doi: 10.15252/embj.201488031. Epub 2014 May 26.

9.

Humanized mouse model to study bacterial infections targeting the microvasculature.

Melican K, Aubey F, Duménil G.

J Vis Exp. 2014 Apr 1;(86). doi: 10.3791/51134.

10.

Complete posttranslational modification mapping of pathogenic Neisseria meningitidis pilins requires top-down mass spectrometry.

Gault J, Malosse C, Machata S, Millien C, Podglajen I, Ploy MC, Costello CE, Duménil G, Chamot-Rooke J.

Proteomics. 2014 May;14(10):1141-51. doi: 10.1002/pmic.201300394. Epub 2014 Mar 12.

11.

Early sequence of events triggered by the interaction of Neisseria meningitidis with endothelial cells.

Soyer M, Charles-Orszag A, Lagache T, Machata S, Imhaus AF, Dumont A, Millien C, Olivo-Marin JC, Duménil G.

Cell Microbiol. 2014 Jun;16(6):878-95. doi: 10.1111/cmi.12248. Epub 2013 Dec 27.

PMID:
24320113
12.

A combined mass spectrometry strategy for complete posttranslational modification mapping of Neisseria meningitidis major pilin.

Gault J, Malosse C, Duménil G, Chamot-Rooke J.

J Mass Spectrom. 2013 Nov;48(11):1199-206. doi: 10.1002/jms.3262.

PMID:
24259208
13.

Assessment of the interplay between blood and skin vascular abnormalities in adult purpura fulminans.

Lerolle N, Carlotti A, Melican K, Aubey F, Pierrot M, Diehl JL, Caille V, Hékimian G, Gandrille S, Mandet C, Bruneval P, Dumenil G, Borgel D.

Am J Respir Crit Care Med. 2013 Sep 15;188(6):684-92. doi: 10.1164/rccm.201302-0228OC.

PMID:
23924269
14.

Leukemia-initiating cell activity requires calcineurin in T-cell acute lymphoblastic leukemia.

Gachet S, Genescà E, Passaro D, Irigoyen M, Alcalde H, Clémenson C, Poglio S, Pflumio F, Janin A, Lasgi C, Dodier S, Soyer M, Duménil G, Ghysdael J.

Leukemia. 2013 Dec;27(12):2289-300. doi: 10.1038/leu.2013.156. Epub 2013 May 21.

PMID:
23689515
15.

A humanized model of microvascular infection.

Melican K, Duménil G.

Future Microbiol. 2013 May;8(5):567-9. doi: 10.2217/fmb.13.35. No abstract available.

16.

Epithelial control of the human pDC response to extracellular bacteria.

Michea P, Vargas P, Donnadieu MH, Rosemblatt M, Bono MR, Duménil G, Soumelis V.

Eur J Immunol. 2013 May;43(5):1264-73. doi: 10.1002/eji.201242990. Epub 2013 Mar 6.

17.

Adhesion of Neisseria meningitidis to dermal vessels leads to local vascular damage and purpura in a humanized mouse model.

Melican K, Michea Veloso P, Martin T, Bruneval P, Duménil G.

PLoS Pathog. 2013 Jan;9(1):e1003139. doi: 10.1371/journal.ppat.1003139. Epub 2013 Jan 24.

18.

The meningococcal minor pilin PilX is responsible for type IV pilus conformational changes associated with signaling to endothelial cells.

Brissac T, Mikaty G, Duménil G, Coureuil M, Nassif X.

Infect Immun. 2012 Sep;80(9):3297-306. doi: 10.1128/IAI.00369-12. Epub 2012 Jul 9.

19.

Tissue microbiology emerging.

Richter-Dahlfors A, Duménil G.

Curr Opin Microbiol. 2012 Feb;15(1):1-2. doi: 10.1016/j.mib.2011.12.005. Epub 2011 Dec 29. No abstract available.

PMID:
22209485
20.

Vascular colonization by Neisseria meningitidis.

Melican K, Dumenil G.

Curr Opin Microbiol. 2012 Feb;15(1):50-6. doi: 10.1016/j.mib.2011.10.008. Epub 2011 Dec 18. Review.

PMID:
22185907
21.

A laminar-flow chamber assay for measuring bacterial adhesion under shear stress.

Soyer M, Duménil G.

Methods Mol Biol. 2012;799:185-95. doi: 10.1007/978-1-61779-346-2_12.

PMID:
21993647
22.

Introducing shear stress in the study of bacterial adhesion.

Soyer M, Duménil G.

J Vis Exp. 2011 Sep 2;(55):e3241. doi: 10.3791/3241.

23.

Revisiting the extracellular lifestyle.

Dumenil G.

Cell Microbiol. 2011 Aug;13(8):1114-21. doi: 10.1111/j.1462-5822.2011.01613.x. Epub 2011 May 25. Review.

PMID:
21615665
24.

Posttranslational modification of pili upon cell contact triggers N. meningitidis dissemination.

Chamot-Rooke J, Mikaty G, Malosse C, Soyer M, Dumont A, Gault J, Imhaus AF, Martin P, Trellet M, Clary G, Chafey P, Camoin L, Nilges M, Nassif X, Duménil G.

Science. 2011 Feb 11;331(6018):778-82. doi: 10.1126/science.1200729.

25.

Pathogens under scrutiny in the south of France.

Caldeira S, Dumenil G.

EMBO Mol Med. 2010 Sep;2(9):331-4. doi: 10.1002/emmm.201000087.

26.

Chilean scientists rally after quake.

Duménil G.

Science. 2010 Mar 19;327(5972):1451-2. doi: 10.1126/science.327.5972.1451-c. No abstract available.

PMID:
20299571
27.

Meningococcal type IV pili recruit the polarity complex to cross the brain endothelium.

Coureuil M, Mikaty G, Miller F, Lécuyer H, Bernard C, Bourdoulous S, Duménil G, Mège RM, Weksler BB, Romero IA, Couraud PO, Nassif X.

Science. 2009 Jul 3;325(5936):83-7. doi: 10.1126/science.1173196. Epub 2009 Jun 11.

28.

Dual role for pilus in adherence to epithelial cells and biofilm formation in Streptococcus agalactiae.

Konto-Ghiorghi Y, Mairey E, Mallet A, Duménil G, Caliot E, Trieu-Cuot P, Dramsi S.

PLoS Pathog. 2009 May;5(5):e1000422. doi: 10.1371/journal.ppat.1000422. Epub 2009 May 8.

29.

Structure and function of interacting IcmR-IcmQ domains from a type IVb secretion system in Legionella pneumophila.

Raychaudhury S, Farelli JD, Montminy TP, Matthews M, Ménétret JF, Duménil G, Roy CR, Head JF, Isberg RR, Akey CW.

Structure. 2009 Apr 15;17(4):590-601. doi: 10.1016/j.str.2009.02.011.

30.

Extracellular bacterial pathogen induces host cell surface reorganization to resist shear stress.

Mikaty G, Soyer M, Mairey E, Henry N, Dyer D, Forest KT, Morand P, Guadagnini S, Prévost MC, Nassif X, Duménil G.

PLoS Pathog. 2009 Feb;5(2):e1000314. doi: 10.1371/journal.ppat.1000314. Epub 2009 Feb 27.

31.

In vitro antimicrobial activity of plants used in Cambodian traditional medicine.

Chea A, Jonville MC, Bun SS, Laget M, Elias R, Duménil G, Balansard G.

Am J Chin Med. 2007;35(5):867-73.

PMID:
17963325
32.

Alternative Neisseria spp. type IV pilin glycosylation with a glyceramido acetamido trideoxyhexose residue.

Chamot-Rooke J, Rousseau B, Lanternier F, Mikaty G, Mairey E, Malosse C, Bouchoux G, Pelicic V, Camoin L, Nassif X, Duménil G.

Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14783-8. Epub 2007 Sep 5.

33.

Cerebral microcirculation shear stress levels determine Neisseria meningitidis attachment sites along the blood-brain barrier.

Mairey E, Genovesio A, Donnadieu E, Bernard C, Jaubert F, Pinard E, Seylaz J, Olivo-Marin JC, Nassif X, Duménil G.

J Exp Med. 2006 Aug 7;203(8):1939-50. Epub 2006 Jul 24.

34.

Distribution and genotoxic effects after successive exposure to different uranium oxide particles inhaled by rats.

Monleau M, De Méo M, Frelon S, Paquet F, Donnadieu-Claraz M, Duménil G, Chazel V.

Inhal Toxicol. 2006 Oct;18(11):885-94.

PMID:
16864406
35.

Genotoxic and inflammatory effects of depleted uranium particles inhaled by rats.

Monleau M, De Méo M, Paquet F, Chazel V, Duménil G, Donnadieu-Claraz M.

Toxicol Sci. 2006 Jan;89(1):287-95. Epub 2005 Oct 12.

PMID:
16221956
36.

Extracellular bacterial pathogens and small GTPases of the Rho family: an unexpected combination.

Duménil G, Nassif X.

Curr Top Microbiol Immunol. 2005;291:11-28. Review.

PMID:
15981457
37.

Evaluation of photolyase (Photosome) repair activity in human keratinocytes after a single dose of ultraviolet B irradiation using the comet assay.

Decome L, De Méo M, Geffard A, Doucet O, Duménil G, Botta A.

J Photochem Photobiol B. 2005 May 13;79(2):101-8. Epub 2005 Jan 22.

PMID:
15878115
38.
39.

IcmR-regulated membrane insertion and efflux by the Legionella pneumophila IcmQ protein.

Duménil G, Montminy TP, Tang M, Isberg RR.

J Biol Chem. 2004 Feb 6;279(6):4686-95. Epub 2003 Nov 18.

40.

Implication of nitro group reduction in the mutagenic and chromosome damaging activities of 22 new 5-nitroisoquinolines by the Salmonella mutagenicity test and the cytokinesis-blocked micronucleus assay.

Orsière T, De Méo M, Rathelot P, Pompili J, Galas M, Castegnaro M, Vanelle P, Duménil G.

Food Chem Toxicol. 2003 Feb;41(2):275-90.

PMID:
12480303
41.

The expression of genes induced in melanocytes by exposure to 365-nm UVA: study by cDNA arrays and real-time quantitative RT-PCR.

Jean S, Bideau C, Bellon L, Halimi G, De Méo M, Orsière T, Dumenil G, Bergé-Lefranc JL, Botta A.

Biochim Biophys Acta. 2001 Dec 3;1522(2):89-96.

PMID:
11750059
42.

Delivering dangerous cargoes.

Isberg RR, Duménil G.

Nat Struct Biol. 2001 Dec;8(12):1006-8. No abstract available.

PMID:
11723464
43.

Evaluation of sunscreen protection in human melanocytes exposed to UVA or UVB irradiation using the alkaline comet assay.

Jean S, De Méo M, Sabatier AS, Laget M, Hubaud JC, Verrando P, Duménil G.

Photochem Photobiol. 2001 Sep;74(3):417-23.

PMID:
11594055
45.

Evaluation of the mutagenic and genotoxic activities of anti-hepatitis B analogs of beta-L-adenosine by the Ames test and the Comet assay.

Placidi L, De Meo M, Gosselin G, Imbach JL, Bryant ML, Dumenil G, Sommadossi JP.

Antiviral Res. 2001 May;50(2):139-45.

PMID:
11369434
46.

Bacterial signals and cell responses during Shigella entry into epithelial cells.

Tran Van Nhieu G, Bourdet-Sicard R, Duménil G, Blocker A, Sansonetti PJ.

Cell Microbiol. 2000 Jun;2(3):187-93. Review.

PMID:
11207575
47.
48.

The protective activity of alpha-hederine against H2O2 genotoxicity in HepG2 cells by alkaline comet assay.

Mba Gachou C, Laget M, Guiraud-Dauriac H, De Méo M, Elias R, Duménil G.

Mutat Res. 1999 Sep 15;445(1):9-20.

PMID:
10521688
49.

Formation of nitrogen-containing metabolites from the main iridoids of Harpagophytum procumbens and H. zeyheri by human intestinal bacteria.

Baghdikian B, Guiraud-Dauriac H, Ollivier E, N'Guyen A, Dumenil G, Balansard G.

Planta Med. 1999 Mar;65(2):164-6.

PMID:
10193209
50.

Interferon alpha inhibits a Src-mediated pathway necessary for Shigella-induced cytoskeletal rearrangements in epithelial cells.

Duménil G, Olivo JC, Pellegrini S, Fellous M, Sansonetti PJ, Nhieu GT.

J Cell Biol. 1998 Nov 16;143(4):1003-12.

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