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Items: 41

1.

Toxoplasma gondii Oocyst Infectivity Assessed Using a Sporocyst-Based Cell Culture Assay Combined with Quantitative PCR for Environmental Applications.

Rousseau A, Escotte-Binet S, La Carbona S, Dumètre A, Chagneau S, Favennec L, Kubina S, Dubey JP, Majou D, Bigot-Clivot A, Villena I, Aubert D.

Appl Environ Microbiol. 2019 Oct 1;85(20). pii: e01189-19. doi: 10.1128/AEM.01189-19. Print 2019 Oct 15.

PMID:
31399406
2.

Evaluation of propidium monoazide-based qPCR to detect viable oocysts of Toxoplasma gondii.

Rousseau A, Villena I, Dumètre A, Escotte-Binet S, Favennec L, Dubey JP, Aubert D, La Carbona S.

Parasitol Res. 2019 Mar;118(3):999-1010. doi: 10.1007/s00436-019-06220-1. Epub 2019 Feb 7.

PMID:
30729299
3.

Assessing viability and infectivity of foodborne and waterborne stages (cysts/oocysts) of Giardia duodenalis, Cryptosporidium spp., and Toxoplasma gondii: a review of methods.

Rousseau A, La Carbona S, Dumètre A, Robertson LJ, Gargala G, Escotte-Binet S, Favennec L, Villena I, Gérard C, Aubert D.

Parasite. 2018;25:14. doi: 10.1051/parasite/2018009. Epub 2018 Mar 19. Review.

4.

Macrophages facilitate the excystation and differentiation of Toxoplasma gondii sporozoites into tachyzoites following oocyst internalisation.

Freppel W, Puech PH, Ferguson DJ, Azas N, Dubey JP, Dumètre A.

Sci Rep. 2016 Sep 19;6:33654. doi: 10.1038/srep33654.

5.

Simultaneous detection of the protozoan parasites Toxoplasma, Cryptosporidium and Giardia in food matrices and their persistence on basil leaves.

Hohweyer J, Cazeaux C, Travaillé E, Languet E, Dumètre A, Aubert D, Terryn C, Dubey JP, Azas N, Houssin M, Loïc F, Villena I, La Carbona S.

Food Microbiol. 2016 Aug;57:36-44. doi: 10.1016/j.fm.2016.01.002. Epub 2016 Jan 12.

PMID:
27052700
6.

Discovery of new thienopyrimidinone derivatives displaying antimalarial properties toward both erythrocytic and hepatic stages of Plasmodium.

Cohen A, Suzanne P, Lancelot JC, Verhaeghe P, Lesnard A, Basmaciyan L, Hutter S, Laget M, Dumètre A, Paloque L, Deharo E, Crozet MD, Rathelot P, Dallemagne P, Lorthiois A, Sibley CH, Vanelle P, Valentin A, Mazier D, Rault S, Azas N.

Eur J Med Chem. 2015 May 5;95:16-28. doi: 10.1016/j.ejmech.2015.03.011. Epub 2015 Mar 10.

PMID:
25791675
7.

A new, rapid and sensitive bioluminescence assay for drug screening on Leishmania.

Paloque L, Vidal N, Casanova M, Dumètre A, Verhaeghe P, Parzy D, Azas N.

J Microbiol Methods. 2013 Dec;95(3):320-3. doi: 10.1016/j.mimet.2013.09.006. Epub 2013 Sep 18.

PMID:
24055386
8.

Tools and methods for detecting and characterizing giardia, cryptosporidium, and toxoplasma parasites in marine mollusks.

Hohweyer J, Dumètre A, Aubert D, Azas N, Villena I.

J Food Prot. 2013 Sep;76(9):1649-57. doi: 10.4315/0362-028X.JFP-13-002. Review.

PMID:
23992514
9.

Mechanics of the Toxoplasma gondii oocyst wall.

Dumètre A, Dubey JP, Ferguson DJ, Bongrand P, Azas N, Puech PH.

Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11535-40. doi: 10.1073/pnas.1308425110. Epub 2013 Jun 24.

10.

A decade of Plasmodium falciparum metabolic pathways of therapeutic interest to develop new selective antimalarial drugs.

Cohen A, Dumètre A, Azas N.

Mini Rev Med Chem. 2013 Jul;13(9):1340-7. Review.

PMID:
23746057
11.

New antiplasmodial alkaloids from Stephania rotunda.

Baghdikian B, Mahiou-Leddet V, Bory S, Bun SS, Dumetre A, Mabrouki F, Hutter S, Azas N, Ollivier E.

J Ethnopharmacol. 2013 Jan 9;145(1):381-5. doi: 10.1016/j.jep.2012.10.052. Epub 2012 Nov 2.

PMID:
23127648
12.

A new synthetic route to original sulfonamide derivatives in 2-trichloromethylquinazoline series: a structure-activity relationship study of antiplasmodial activity.

Primas N, Verhaeghe P, Cohen A, Kieffer C, Dumètre A, Hutter S, Rault S, Rathelot P, Azas N, Vanelle P.

Molecules. 2012 Jul 5;17(7):8105-17. doi: 10.3390/molecules17078105.

13.

Discovery of a new antileishmanial hit in 8-nitroquinoline series.

Paloque L, Verhaeghe P, Casanova M, Castera-Ducros C, Dumètre A, Mbatchi L, Hutter S, Kraiem-M'rabet M, Laget M, Remusat V, Rault S, Rathelot P, Azas N, Vanelle P.

Eur J Med Chem. 2012 Aug;54:75-86. doi: 10.1016/j.ejmech.2012.04.029. Epub 2012 May 2.

PMID:
22608675
14.

Quantitative estimation of the viability of Toxoplasma gondii oocysts in soil.

Lélu M, Villena I, Dardé ML, Aubert D, Geers R, Dupuis E, Marnef F, Poulle ML, Gotteland C, Dumètre A, Gilot-Fromont E.

Appl Environ Microbiol. 2012 Aug;78(15):5127-32. doi: 10.1128/AEM.00246-12. Epub 2012 May 11.

15.

HPLC analysis of Stephania rotunda extracts and correlation with antiplasmodial activity.

Bory S, Bun SS, Baghdikian B, Dumètre A, Hutter S, Mabrouki F, Bun H, Elias R, Azas N, Ollivier E.

Phytother Res. 2013 Feb;27(2):278-84. doi: 10.1002/ptr.4710. Epub 2012 May 8.

PMID:
22566106
16.

Preparation and antiprotozoal evaluation of promising β-carboline alkaloids.

Gellis A, Dumètre A, Lanzada G, Hutter S, Ollivier E, Vanelle P, Azas N.

Biomed Pharmacother. 2012 Jul;66(5):339-47. doi: 10.1016/j.biopha.2011.12.006. Epub 2012 Feb 17.

PMID:
22397756
17.

Interaction forces drive the environmental transmission of pathogenic protozoa.

Dumètre A, Aubert D, Puech PH, Hohweyer J, Azas N, Villena I.

Appl Environ Microbiol. 2012 Feb;78(4):905-12. doi: 10.1128/AEM.06488-11. Epub 2011 Dec 9. Review.

18.

4-Thiophenoxy-2-trichloromethyquinazolines display in vitro selective antiplasmodial activity against the human malaria parasite Plasmodium falciparum.

Verhaeghe P, Dumètre A, Castera-Ducros C, Hutter S, Laget M, Fersing C, Prieri M, Yzombard J, Sifredi F, Rault S, Rathelot P, Vanelle P, Azas N.

Bioorg Med Chem Lett. 2011 Oct 1;21(19):6003-6. doi: 10.1016/j.bmcl.2011.06.113. Epub 2011 Jul 2.

PMID:
21852132
19.

Development of a sensitive method for Toxoplasma gondii oocyst extraction in soil.

Lélu M, Gilot-Fromont E, Aubert D, Richaume A, Afonso E, Dupuis E, Gotteland C, Marnef F, Poulle ML, Dumètre A, Thulliez P, Dardé ML, Villena I.

Vet Parasitol. 2011 Dec 29;183(1-2):59-67. doi: 10.1016/j.vetpar.2011.06.018. Epub 2011 Jun 25.

PMID:
21764217
20.

Targeting the human malaria parasite Plasmodium falciparum: in vitro identification of a new antiplasmodial hit in 4-phenoxy-2-trichloromethylquinazoline series.

Castera-Ducros C, Azas N, Verhaeghe P, Hutter S, Garrigue P, Dumètre A, Mbatchi L, Laget M, Remusat V, Sifredi F, Rault S, Rathelot P, Vanelle P.

Eur J Med Chem. 2011 Sep;46(9):4184-91. doi: 10.1016/j.ejmech.2011.06.021. Epub 2011 Jun 23.

PMID:
21741131
21.

Synthesis and evaluation of monoamidoxime derivatives: toward new antileishmanial compounds.

Paloque L, Bouhlel A, Curti C, Dumètre A, Verhaeghe P, Azas N, Vanelle P.

Eur J Med Chem. 2011 Jul;46(7):2984-91. doi: 10.1016/j.ejmech.2011.04.026. Epub 2011 Apr 15.

PMID:
21555166
22.

Synthesis and evaluation of original amidoximes as antileishmanial agents.

Bouhlel A, Curti C, Dumètre A, Laget M, Crozet MD, Azas N, Vanelle P.

Bioorg Med Chem. 2010 Oct 15;18(20):7310-20. doi: 10.1016/j.bmc.2010.06.099. Epub 2010 Jul 11.

PMID:
20833057
23.

Anti-HIV and antiplasmodial activity of original flavonoid derivatives.

Casano G, Dumètre A, Pannecouque C, Hutter S, Azas N, Robin M.

Bioorg Med Chem. 2010 Aug 15;18(16):6012-23. doi: 10.1016/j.bmc.2010.06.067. Epub 2010 Jun 25.

PMID:
20638854
24.

Contribution of treated wastewater to the microbiological quality of Seine River in Paris.

Moulin L, Richard F, Stefania S, Goulet M, Gosselin S, Gonçalves A, Rocher V, Paffoni C, Dumètre A.

Water Res. 2010 Oct;44(18):5222-31. doi: 10.1016/j.watres.2010.06.037. Epub 2010 Jun 22.

PMID:
20630555
25.

Original quinazoline derivatives displaying antiplasmodial properties.

Kabri Y, Azas N, Dumètre A, Hutter S, Laget M, Verhaeghe P, Gellis A, Vanelle P.

Eur J Med Chem. 2010 Feb;45(2):616-22. doi: 10.1016/j.ejmech.2009.11.005. Epub 2009 Nov 6.

PMID:
19926173
26.

Synthesis and antiprotozoal activity of 4-arylcoumarins.

Pierson JT, Dumètre A, Hutter S, Delmas F, Laget M, Finet JP, Azas N, Combes S.

Eur J Med Chem. 2010 Mar;45(3):864-9. doi: 10.1016/j.ejmech.2009.10.022. Epub 2009 Oct 23.

PMID:
19914747
27.

Synthesis and biological evaluation of new heterocyclic quinolinones as anti-parasite and anti-HIV drug candidates.

Darque A, Dumètre A, Hutter S, Casano G, Robin M, Pannecouque C, Azas N.

Bioorg Med Chem Lett. 2009 Oct 15;19(20):5962-4. doi: 10.1016/j.bmcl.2009.08.013. Epub 2009 Aug 7.

PMID:
19748781
28.

Synthesis and in vitro antiplasmodial evaluation of 4-anilino-2-trichloromethylquinazolines.

Verhaeghe P, Azas N, Hutter S, Castera-Ducros C, Laget M, Dumètre A, Gasquet M, Reboul JP, Rault S, Rathelot P, Vanelle P.

Bioorg Med Chem. 2009 Jul 1;17(13):4313-22. doi: 10.1016/j.bmc.2009.05.022. Epub 2009 May 15.

PMID:
19482476
29.

Detection of Toxoplasma gondii oocysts in environmental soil samples using molecular methods.

Lass A, Pietkiewicz H, Modzelewska E, Dumètre A, Szostakowska B, Myjak P.

Eur J Clin Microbiol Infect Dis. 2009 Jun;28(6):599-605. doi: 10.1007/s10096-008-0681-5. Epub 2008 Dec 23.

PMID:
19104853
30.

Congenital toxoplasmosis and reinfection during pregnancy: case report, strain characterization, experimental model of reinfection, and review.

Elbez-Rubinstein A, Ajzenberg D, Dardé ML, Cohen R, Dumètre A, Yera H, Gondon E, Janaud JC, Thulliez P.

J Infect Dis. 2009 Jan 15;199(2):280-5. doi: 10.1086/595793. Review.

PMID:
19032062
31.

Monitoring of Cryptosporidium and Giardia river contamination in Paris area.

Mons C, Dumètre A, Gosselin S, Galliot C, Moulin L.

Water Res. 2009 Jan;43(1):211-7. doi: 10.1016/j.watres.2008.10.024. Epub 2008 Nov 1.

PMID:
18996551
32.

Effects of ozone and ultraviolet radiation treatments on the infectivity of Toxoplasma gondii oocysts.

Dumètre A, Le Bras C, Baffet M, Meneceur P, Dubey JP, Derouin F, Duguet JP, Joyeux M, Moulin L.

Vet Parasitol. 2008 May 31;153(3-4):209-13. doi: 10.1016/j.vetpar.2008.02.004. Epub 2008 Feb 13.

PMID:
18355965
33.

Prevalence of Toxoplasma gondii in raptors from France.

Aubert D, Terrier ME, Dumètre A, Barrat J, Villena I.

J Wildl Dis. 2008 Jan;44(1):172-3.

PMID:
18263835
34.

Serological survey of caprine toxoplasmosis in Ethiopia: prevalence and risk factors.

Teshale S, Dumètre A, Dardé ML, Merga B, Dorchies P.

Parasite. 2007 Jun;14(2):155-9.

35.

Detection of Toxoplasma gondii in water by an immunomagnetic separation method targeting the sporocysts.

Dumètre A, Dardé ML.

Parasitol Res. 2007 Sep;101(4):989-96. Epub 2007 May 26.

PMID:
17530288
36.

Toxoplasma gondii infection in sheep from Haute-Vienne, France: seroprevalence and isolate genotyping by microsatellite analysis.

Dumètre A, Ajzenberg D, Rozette L, Mercier A, Dardé ML.

Vet Parasitol. 2006 Dec 20;142(3-4):376-9. Epub 2006 Aug 21.

PMID:
16919879
37.

Multiplex PCR for typing strains of Toxoplasma gondii.

Ajzenberg D, Dumètre A, Dardé ML.

J Clin Microbiol. 2005 Apr;43(4):1940-3.

38.

Immunomagnetic separation of Toxoplasma gondii oocysts using a monoclonal antibody directed against the oocyst wall.

Dumètre A, Dardé ML.

J Microbiol Methods. 2005 May;61(2):209-17. Epub 2005 Jan 6.

PMID:
15722147
39.

Genetic diversity, clonality and sexuality in Toxoplasma gondii.

Ajzenberg D, Bañuls AL, Su C, Dumètre A, Demar M, Carme B, Dardé ML.

Int J Parasitol. 2004 Sep;34(10):1185-96.

PMID:
15380690
40.

Purification of Toxoplasma gondii oocysts by cesium chloride gradient.

Dumètre A, Dardé ML.

J Microbiol Methods. 2004 Mar;56(3):427-30.

PMID:
14967234
41.

How to detect Toxoplasma gondii oocysts in environmental samples?

Dumètre A, Dardé ML.

FEMS Microbiol Rev. 2003 Dec;27(5):651-61. Review.

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