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Items: 30


On the Fly: Interactions Between Birds, Mosquitoes, and Environment That Have Molded West Nile Virus Genomic Structure Over Two Decades.

Duggal NK, Langwig KE, Ebel GD, Brault AC.

J Med Entomol. 2019 Sep 24. pii: tjz112. doi: 10.1093/jme/tjz112. [Epub ahead of print]


Duration of seminal Zika viral RNA shedding in immunocompetent mice inoculated with Asian and African genotype viruses.

McDonald EM, Duggal NK, Delorey MJ, Oksanish J, Ritter JM, Brault AC.

Virology. 2019 Jun 20;535:1-10. doi: 10.1016/j.virol.2019.06.010. [Epub ahead of print]


Mutations present in a low-passage Zika virus isolate result in attenuated pathogenesis in mice.

Duggal NK, McDonald EM, Weger-Lucarelli J, Hawks SA, Ritter JM, Romo H, Ebel GD, Brault AC.

Virology. 2019 Apr;530:19-26. doi: 10.1016/j.virol.2019.02.004. Epub 2019 Feb 7.


Heartland Virus Epidemiology, Vector Association, and Disease Potential.

Brault AC, Savage HM, Duggal NK, Eisen RJ, Staples JE.

Viruses. 2018 Sep 14;10(9). pii: E498. doi: 10.3390/v10090498. Review.


Infection of epididymal epithelial cells and leukocytes drives seminal shedding of Zika virus in a mouse model.

McDonald EM, Duggal NK, Ritter JM, Brault AC.

PLoS Negl Trop Dis. 2018 Aug 2;12(8):e0006691. doi: 10.1371/journal.pntd.0006691. eCollection 2018 Aug.


Zika Virus Shedding in Semen of Symptomatic Infected Men.

Mead PS, Duggal NK, Hook SA, Delorey M, Fischer M, Olzenak McGuire D, Becksted H, Max RJ, Anishchenko M, Schwartz AM, Tzeng WP, Nelson CA, McDonald EM, Brooks JT, Brault AC, Hinckley AF.

N Engl J Med. 2018 Apr 12;378(15):1377-1385. doi: 10.1056/NEJMoa1711038.


Sexual transmission of Zika virus enhances in utero transmission in a mouse model.

Duggal NK, McDonald EM, Ritter JM, Brault AC.

Sci Rep. 2018 Mar 14;8(1):4510. doi: 10.1038/s41598-018-22840-6.


Increases in the competitive fitness of West Nile virus isolates after introduction into California.

Worwa G, Hutton AA, Frey M, Duggal NK, Brault AC, Reisen WK.

Virology. 2018 Jan 15;514:170-181. doi: 10.1016/j.virol.2017.11.017. Epub 2017 Nov 28.


A Zika Vaccine Targeting NS1 Protein Protects Immunocompetent Adult Mice in a Lethal Challenge Model.

Brault AC, Domi A, McDonald EM, Talmi-Frank D, McCurley N, Basu R, Robinson HL, Hellerstein M, Duggal NK, Bowen RA, Guirakhoo F.

Sci Rep. 2017 Nov 7;7(1):14769. doi: 10.1038/s41598-017-15039-8.


Pathogenesis and sexual transmission of Spondweni and Zika viruses.

McDonald EM, Duggal NK, Brault AC.

PLoS Negl Trop Dis. 2017 Oct 6;11(10):e0005990. doi: 10.1371/journal.pntd.0005990. eCollection 2017 Oct.


Differential Neurovirulence of African and Asian Genotype Zika Virus Isolates in Outbred Immunocompetent Mice.

Duggal NK, Ritter JM, McDonald EM, Romo H, Guirakhoo F, Davis BS, Chang GJ, Brault AC.

Am J Trop Med Hyg. 2017 Nov;97(5):1410-1417. doi: 10.4269/ajtmh.17-0263. Epub 2017 Aug 18.


Rescue and Characterization of Recombinant Virus from a New World Zika Virus Infectious Clone.

Weger-Lucarelli J, Duggal NK, Brault AC, Geiss BJ, Ebel GD.

J Vis Exp. 2017 Jun 7;(124). doi: 10.3791/55857.


Transmission Incompetence of Culex quinquefasciatus and Culex pipiens pipiens from North America for Zika Virus.

Kenney JL, Romo H, Duggal NK, Tzeng WP, Burkhalter KL, Brault AC, Savage HM.

Am J Trop Med Hyg. 2017 May;96(5):1235-1240. doi: 10.4269/ajtmh.16-0865.


Rapid and specific detection of Asian- and African-lineage Zika viruses.

Chotiwan N, Brewster CD, Magalhaes T, Weger-Lucarelli J, Duggal NK, Rückert C, Nguyen C, Garcia Luna SM, Fauver JR, Andre B, Gray M, Black WC 4th, Kading RC, Ebel GD, Kuan G, Balmaseda A, Jaenisch T, Marques ETA, Brault AC, Harris E, Foy BD, Quackenbush SL, Perera R, Rovnak J.

Sci Transl Med. 2017 May 3;9(388). pii: eaag0538. doi: 10.1126/scitranslmed.aag0538.


Erratum for Weger-Lucarelli et al., "Development and Characterization of Recombinant Virus Generated from a New World Zika Virus Infectious Clone".

Weger-Lucarelli J, Duggal NK, Bullard-Feibelman K, Veselinovic M, Romo H, Nguyen C, Rückert C, Brault AC, Bowen RA, Stenglein M, Geiss BJ, Ebel GD.

J Virol. 2017 Mar 29;91(8). pii: e00172-17. doi: 10.1128/JVI.00172-17. Print 2017 Apr 15. No abstract available.


Frequent Zika Virus Sexual Transmission and Prolonged Viral RNA Shedding in an Immunodeficient Mouse Model.

Duggal NK, Ritter JM, Pestorius SE, Zaki SR, Davis BS, Chang GJ, Bowen RA, Brault AC.

Cell Rep. 2017 Feb 14;18(7):1751-1760. doi: 10.1016/j.celrep.2017.01.056.


Development and Characterization of Recombinant Virus Generated from a New World Zika Virus Infectious Clone.

Weger-Lucarelli J, Duggal NK, Bullard-Feibelman K, Veselinovic M, Romo H, Nguyen C, Rückert C, Brault AC, Bowen RA, Stenglein M, Geiss BJ, Ebel GD.

J Virol. 2016 Dec 16;91(1). pii: e01765-16. doi: 10.1128/JVI.01765-16. Print 2017 Jan 1. Erratum in: J Virol. 2017 Mar 29;91(8):.


MicroRNA reduction of neuronal West Nile virus replication attenuates and affords a protective immune response in mice.

Brostoff T, Pesavento PA, Barker CM, Kenney JL, Dietrich EA, Duggal NK, Bosco-Lauth AM, Brault AC.

Vaccine. 2016 Oct 17;34(44):5366-5375. doi: 10.1016/j.vaccine.2016.08.063. Epub 2016 Sep 13.


Potential for Co-Infection of a Mosquito-Specific Flavivirus, Nhumirim Virus, to Block West Nile Virus Transmission in Mosquitoes.

Goenaga S, Kenney JL, Duggal NK, Delorey M, Ebel GD, Zhang B, Levis SC, Enria DA, Brault AC.

Viruses. 2015 Nov 11;7(11):5801-12. doi: 10.3390/v7112911.


Genotype-specific variation in West Nile virus dispersal in California.

Duggal NK, Reisen WK, Fang Y, Newman RM, Yang X, Ebel GD, Brault AC.

Virology. 2015 Nov;485:79-85. doi: 10.1016/j.virol.2015.07.004. Epub 2015 Jul 25.


Experimental evolution of an RNA virus in wild birds: evidence for host-dependent impacts on population structure and competitive fitness.

Grubaugh ND, Smith DR, Brackney DE, Bosco-Lauth AM, Fauver JR, Campbell CL, Felix TA, Romo H, Duggal NK, Dietrich EA, Eike T, Beane JE, Bowen RA, Black WC, Brault AC, Ebel GD.

PLoS Pathog. 2015 May 20;11(5):e1004874. doi: 10.1371/journal.ppat.1004874. eCollection 2015 May.


Evidence for co-evolution of West Nile Virus and house sparrows in North America.

Duggal NK, Bosco-Lauth A, Bowen RA, Wheeler SS, Reisen WK, Felix TA, Mann BR, Romo H, Swetnam DM, Barrett AD, Brault AC.

PLoS Negl Trop Dis. 2014 Oct 30;8(10):e3262. doi: 10.1371/journal.pntd.0003262. eCollection 2014 Oct.


Host competence and helicase activity differences exhibited by West Nile viral variants expressing NS3-249 amino acid polymorphisms.

Langevin SA, Bowen RA, Reisen WK, Andrade CC, Ramey WN, Maharaj PD, Anishchenko M, Kenney JL, Duggal NK, Romo H, Bera AK, Sanders TA, Bosco-Lauth A, Smith JL, Kuhn R, Brault AC.

PLoS One. 2014 Jun 27;9(6):e100802. doi: 10.1371/journal.pone.0100802. eCollection 2014.


Sequence analyses of 2012 West Nile virus isolates from Texas fail to associate viral genetic factors with outbreak magnitude.

Duggal NK, D'Anton M, Xiang J, Seiferth R, Day J, Nasci R, Brault AC.

Am J Trop Med Hyg. 2013 Aug;89(2):205-210. doi: 10.4269/ajtmh.13-0140. Epub 2013 Jul 1.


Identification and antiviral activity of common polymorphisms in the APOBEC3 locus in human populations.

Duggal NK, Fu W, Akey JM, Emerman M.

Virology. 2013 Sep 1;443(2):329-37. doi: 10.1016/j.virol.2013.05.016. Epub 2013 Jun 10.


Evolutionary conflicts between viruses and restriction factors shape immunity.

Duggal NK, Emerman M.

Nat Rev Immunol. 2012 Oct;12(10):687-95. doi: 10.1038/nri3295. Epub 2012 Sep 14. Review.


The breadth of antiviral activity of Apobec3DE in chimpanzees has been driven by positive selection.

Duggal NK, Malik HS, Emerman M.

J Virol. 2011 Nov;85(21):11361-71. doi: 10.1128/JVI.05046-11. Epub 2011 Aug 10.


Pseudodiploid genome organization AIDS full-length human immunodeficiency virus type 1 DNA synthesis.

King SR, Duggal NK, Ndongmo CB, Pacut C, Telesnitsky A.

J Virol. 2008 Mar;82(5):2376-84. Epub 2007 Dec 19.


Profiles of growth hormone (GH)-regulated genes reveal time-dependent responses and identify a mechanism for regulation of activating transcription factor 3 by GH.

Huo JS, McEachin RC, Cui TX, Duggal NK, Hai T, States DJ, Schwartz J.

J Biol Chem. 2006 Feb 17;281(7):4132-41. Epub 2005 Dec 1.

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