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S100A11/ANXA2 belongs to a tumour suppressor/oncogene network deregulated early with steatosis and involved in inflammation and hepatocellular carcinoma development.

Sobolewski C, Abegg D, Berthou F, Dolicka D, Calo N, Sempoux C, Fournier M, Maeder C, Ay AS, Clavien PA, Humar B, Dufour JF, Adibekian A, Foti M.

Gut. 2020 Jan 9. pii: gutjnl-2019-319019. doi: 10.1136/gutjnl-2019-319019. [Epub ahead of print]


Recent advances in alcohol-related liver disease (ALD): summary of a Gut round table meeting.

Avila MA, Dufour JF, Gerbes AL, Zoulim F, Bataller R, Burra P, Cortez-Pinto H, Gao B, Gilmore I, Mathurin P, Moreno C, Poznyak V, Schnabl B, Szabo G, Thiele M, Thursz MR.

Gut. 2019 Dec 26. pii: gutjnl-2019-319720. doi: 10.1136/gutjnl-2019-319720. [Epub ahead of print] Review.


Nonalcoholic fatty liver disease burden - Switzerland 2018-2030.

Goossens N, Bellentani S, Cerny A, Dufour JF, Jornayvaz FR, Mertens J, Moriggia A, Muellhaupt B, Negro F, Razavi H, Semela D, Estes C.

Swiss Med Wkly. 2019 Dec 17;149:w20152. doi: 10.4414/smw.2019.20152. eCollection 2019 Dec 16.


Controlled attenuation parameter reflects steatosis in compensated advanced chronic liver disease.

Piccinni R, Rodrigues SG, Montani M, Murgia G, Delgado MG, Casu S, Stirnimann G, Semmo N, De Gottardi A, Dufour JF, Berzigotti A.

Liver Int. 2019 Dec 10. doi: 10.1111/liv.14325. [Epub ahead of print]


Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial.

Younossi ZM, Ratziu V, Loomba R, Rinella M, Anstee QM, Goodman Z, Bedossa P, Geier A, Beckebaum S, Newsome PN, Sheridan D, Sheikh MY, Trotter J, Knapple W, Lawitz E, Abdelmalek MF, Kowdley KV, Montano-Loza AJ, Boursier J, Mathurin P, Bugianesi E, Mazzella G, Olveira A, Cortez-Pinto H, Graupera I, Orr D, Gluud LL, Dufour JF, Shapiro D, Campagna J, Zaru L, MacConell L, Shringarpure R, Harrison S, Sanyal AJ; REGENERATE Study Investigators.

Lancet. 2019 Dec 14;394(10215):2184-2196. doi: 10.1016/S0140-6736(19)33041-7. Epub 2019 Dec 5.


Repeated Fractions of X-Radiation to the Breast Fat Pads of Mice Augment Activation of the Autotaxin-Lysophosphatidate-Inflammatory Cycle.

Meng G, Wuest M, Tang X, Dufour J, Zhao Y, Curtis JM, McMullen TPW, Murray D, Wuest F, Brindley DN.

Cancers (Basel). 2019 Nov 19;11(11). pii: E1816. doi: 10.3390/cancers11111816.


Maternal exercise before and during pregnancy alleviates metabolic dysfunction associated with high-fat diet in pregnant mice, without significant changes in gut microbiota.

Chung E, Grue KA, Kaur G, Mallory B, Serrano CR, Ullevig SL, Kottapalli KR, Lee SC, Dufour JM, Shen CL, Umeda M.

Nutr Res. 2019 Sep;69:42-57. doi: 10.1016/j.nutres.2019.08.002. Epub 2019 Aug 8.


Active vision : on the relevance of a bio-inspired approach for object detection.

Hoang K, Pitti A, Goudou JF, Dufour JY, Gaussier P.

Bioinspir Biomim. 2019 Oct 22. doi: 10.1088/1748-3190/ab504c. [Epub ahead of print]


Genetic variation in HSD17B13 reduces the risk of developing cirrhosis and hepatocellular carcinoma in alcohol misusers.

Stickel F, Lutz P, Buch S, Nischalke HD, Silva I, Rausch V, Fischer J, Weiss KH, Gotthardt D, Rosendahl J, Marot A, Elamly M, Krawczyk M, Casper M, Lammert F, Buckley TW, McQuillin A, Spengler U, Eyer F, Vogel A, Marhenke S, von Felden J, Wege H, Sharma R, Atkinson S, Franke A, Nehring S, Moser V, Schafmayer C, Spahr L, Lackner C, Stauber RE, Canbay A, Link A, Valenti L, Grove JI, Aithal GP, Marquardt JU, Fateen W, Zopf S, Dufour JF, Trebicka J, Datz C, Deltenre P, Mueller S, Berg T, Hampe J, Morgan MY.

Hepatology. 2019 Oct 19. doi: 10.1002/hep.30996. [Epub ahead of print]


Smoking favours hepatocellular carcinoma.

Guarino M, Dufour JF.

Ann Transl Med. 2019 Jul;7(Suppl 3):S99. doi: 10.21037/atm.2019.04.90. No abstract available.


First-in-Human Phase I Study of Fisogatinib (BLU-554) Validates Aberrant FGF19 Signaling as a Driver Event in Hepatocellular Carcinoma.

Kim RD, Sarker D, Meyer T, Yau T, Macarulla T, Park JW, Choo SP, Hollebecque A, Sung MW, Lim HY, Mazzaferro V, Trojan J, Zhu AX, Yoon JH, Sharma S, Lin ZZ, Chan SL, Faivre S, Feun LG, Yen CJ, Dufour JF, Palmer DH, Llovet JM, Manoogian M, Tugnait M, Stransky N, Hagel M, Kohl NE, Lengauer C, Sherwin CA, Schmidt-Kittler O, Hoeflich KP, Shi H, Wolf BB, Kang YK.

Cancer Discov. 2019 Dec;9(12):1696-1707. doi: 10.1158/2159-8290.CD-19-0555. Epub 2019 Oct 1.


Inhibition of Autotaxin with GLPG1690 Increases the Efficacy of Radiotherapy and Chemotherapy in a Mouse Model of Breast Cancer.

Tang X, Wuest M, Benesch MGK, Dufour J, Zhao Y, Curtis JM, Monjardet A, Heckmann B, Murray D, Wuest F, Brindley DN.

Mol Cancer Ther. 2020 Jan;19(1):63-74. doi: 10.1158/1535-7163.MCT-19-0386. Epub 2019 Sep 23.


Nicotinamide and NAFLD: Is There Nothing New Under the Sun?

Guarino M, Dufour JF.

Metabolites. 2019 Sep 10;9(9). pii: E180. doi: 10.3390/metabo9090180. Review.


ApiAppS: A Project to Study and Help Practitioners in Recommending mHealth Apps and Devices to Their Patients.

Dufour JC, Grosjean J, Darmoni S, Yasini M, Marchand G, Simon C, Sarradon-Eck A, Préau M, Darmon D, Schuers M, Hassanaly P, Giorgi R.

Stud Health Technol Inform. 2019 Aug 21;264:1919-1920. doi: 10.3233/SHTI190713.


Stereotactic image-guided microwave ablation of hepatocellular carcinoma using a computer-assisted navigation system.

Lachenmayer A, Tinguely P, Maurer MH, Frehner L, Knöpfli M, Peterhans M, Weber S, Dufour JF, Candinas D, Banz V.

Liver Int. 2019 Oct;39(10):1975-1985. doi: 10.1111/liv.14187. Epub 2019 Jul 28.


Sustained virologic response to direct-acting antiviral therapy in patients with chronic hepatitis C and hepatocellular carcinoma: A systematic review and meta-analysis.

Ji F, Yeo YH, Wei MT, Ogawa E, Enomoto M, Lee DH, Iio E, Lubel J, Wang W, Wei B, Ide T, Preda CM, Conti F, Minami T, Bielen R, Sezaki H, Barone M, Kolly P, Chu PS, Virlogeux V, Eurich D, Henry L, Bass MB, Kanai T, Dang S, Li Z, Dufour JF, Zoulim F, Andreone P, Cheung RC, Tanaka Y, Furusyo N, Toyoda H, Tamori A, Nguyen MH.

J Hepatol. 2019 Sep;71(3):473-485. doi: 10.1016/j.jhep.2019.04.017. Epub 2019 May 13.


Repertoire of human breast and milk microbiota: a systematic review.

Togo A, Dufour JC, Lagier JC, Dubourg G, Raoult D, Million M.

Future Microbiol. 2019 May;14:623-641. doi: 10.2217/fmb-2018-0317. Epub 2019 Apr 26.


Incidence of hepatocellular carcinoma in HIV/HBV-coinfected patients on tenofovir therapy: Relevance for screening strategies.

Wandeler G, Mauron E, Atkinson A, Dufour JF, Kraus D, Reiss P, Peters L, Dabis F, Fehr J, Bernasconi E, van der Valk M, Smit C, Gjærde LK, Rockstroh J, Neau D, Bonnet F, Rauch A; Swiss HIV Cohort Study, Athena Observational Cohort Study, EuroSIDA, ANRS CO3 Aquitaine Cohort.

J Hepatol. 2019 Aug;71(2):274-280. doi: 10.1016/j.jhep.2019.03.032. Epub 2019 Apr 6.


When lifestyles sign.

Guarino M, Bovet C, Dufour JF.

Hepatobiliary Surg Nutr. 2019 Feb;8(1):69-71. doi: 10.21037/hbsn.2018.11.07. No abstract available.


Changing Epidemiology of HCC: How to Screen and Identify Patients at Risk?

Lange N, Dufour JF.

Dig Dis Sci. 2019 Apr;64(4):903-909. doi: 10.1007/s10620-019-05515-8. Review.


Retreatment of patients who failed glecaprevir/pibrentasvir treatment for hepatitis C virus infection.

Wyles D, Weiland O, Yao B, Weilert F, Dufour JF, Gordon SC, Stoehr A, Brown A, Mauss S, Zhang Z, Pilot-Matias T, Rodrigues L Jr, Mensa FJ, Poordad F.

J Hepatol. 2019 May;70(5):1019-1023. doi: 10.1016/j.jhep.2019.01.031. Epub 2019 Mar 8. No abstract available.


Effect of annatto-extracted tocotrienols and green tea polyphenols on glucose homeostasis and skeletal muscle metabolism in obese male mice.

Chung E, Campise SN, Joiner HE, Tomison MD, Kaur G, Dufour JM, Cole L, Ramalingam L, Moustaid-Moussa N, Shen CL.

J Nutr Biochem. 2019 May;67:36-43. doi: 10.1016/j.jnutbio.2019.01.021. Epub 2019 Feb 10.


Hepatic gene expression in mouse models of non-alcoholic fatty liver disease after acute exercise.

Piguet AC, Guarino M, Potaczek DP, Garn H, Dufour JF.

Hepatol Res. 2019 Jun;49(6):637-652. doi: 10.1111/hepr.13323. Epub 2019 Apr 7.


Abnormal T-cell phenotype in episodic angioedema with hypereosinophilia (Gleich's syndrome): frequency, clinical implication and prognosis.

Abisror N, Mekinian A, Dechartres A, Groh M, Berezne A, Noel N, Morati C, Haroche J, Hunault-Berger M, Agard C, Ackermann F, Geffray L, Jeandel PY, Trouillier S, Quemeneur T, Dufour JF, Lamaury I, Lhote F, Lefèvre G, Fain O, Kahn JE; French Eosinophil Network.

J Am Acad Dermatol. 2019 Feb 6. pii: S0190-9622(19)30196-3. doi: 10.1016/j.jaad.2019.02.001. [Epub ahead of print]


Is ex vivo liver resection and autotransplantation a valid alternative treatment for end-stage hepatic alveolar echinococcosis in Europe?

Beldi G, Vuitton D, Lachenmayer A, Heyd B, Dufour JF, Richou C, Candinas D, Bresson-Hadni S.

J Hepatol. 2019 May;70(5):1030-1031. doi: 10.1016/j.jhep.2018.12.011. Epub 2019 Feb 2. No abstract available.


Coincidence of NOD2-Associated Autoinflammatory Disease (Yao Syndrome) and HCV Infection With Fatal Consequences: Interaction Between Genes and Environment.

Trueb B, Zhuang L, Keller I, von Köckritz L, Kuchen S, Dufour JF, Villiger PM.

J Clin Rheumatol. 2018 Dec 28. doi: 10.1097/RHU.0000000000000963. [Epub ahead of print] No abstract available.


Impact of two postural assist exoskeletons on biomechanical loading of the lumbar spine.

Picchiotti MT, Weston EB, Knapik GG, Dufour JS, Marras WS.

Appl Ergon. 2019 Feb;75:1-7. doi: 10.1016/j.apergo.2018.09.006. Epub 2018 Sep 16.


Recurrence of Hepatitis B Infection in Liver Transplant Patients Receiving Long-Term Hepatitis B Immunoglobulin Prophylaxis.

Beckebaum S, Herzer K, Bauhofer A, Gelson W, De Simone P, de Man R, Engelmann C, Müllhaupt B, Vionnet J, Salizzoni M, Volpes R, Ercolani G, De Carlis L, Angeli P, Burra P, Dufour JF, Rossi M, Cillo U, Neumann U, Fischer L, Niemann G, Toti L, Tisone G.

Ann Transplant. 2018 Nov 13;23:789-801. doi: 10.12659/AOT.910176.


Repertoire of bacterial species cultured from the human oral cavity and respiratory tract.

Fonkou MD, Dufour JC, Dubourg G, Raoult D.

Future Microbiol. 2018 Nov;13:1611-1624. doi: 10.2217/fmb-2018-0181. Epub 2018 Nov 12.


Human Bacterial Repertoire of the Urinary Tract: a Potential Paradigm Shift.

Morand A, Cornu F, Dufour JC, Tsimaratos M, Lagier JC, Raoult D.

J Clin Microbiol. 2019 Feb 27;57(3). pii: e00675-18. doi: 10.1128/JCM.00675-18. Print 2019 Mar. Review.


Robust eco-efficiency assessment of hydrogen from biomass gasification as an alternative to conventional hydrogen: A life-cycle study with and without external costs.

Valente A, Iribarren D, Gálvez-Martos JL, Dufour J.

Sci Total Environ. 2019 Feb 10;650(Pt 1):1465-1475. doi: 10.1016/j.scitotenv.2018.09.089. Epub 2018 Sep 8.


Treatment of non-alcoholic steatohepatitis patients with vitamin D: a double-blinded, randomized, placebo-controlled pilot study.

Geier A, Eichinger M, Stirnimann G, Semela D, Tay F, Seifert B, Tschopp O, Bantel H, Jahn D, Marques Maggio E, Saleh L, Bischoff-Ferrari HA, Müllhaupt B, Dufour JF.

Scand J Gastroenterol. 2018 Sep;53(9):1114-1120. doi: 10.1080/00365521.2018.1501091. Epub 2018 Sep 29.


Inflammation and Microbiota Fingerprint: Delphi's Oracle for Nonalcoholic Fatty Liver Disease-Related Hepatocellular Carcinoma?

Cassano M, Dufour JF.

Hepatology. 2019 Jan;69(1):12-15. doi: 10.1002/hep.30267. Epub 2018 Dec 22. No abstract available.


Exercise Improves Outcomes of Surgery on Fatty Liver in Mice: A Novel Effect Mediated by the AMPK Pathway.

Linecker M, Frick L, Kron P, Limani P, Kambakamba P, Tschuor C, Langiewicz M, Kachaylo E, Tian Y, Schneider MA, Ungethüm U, Calo N, Foti M, Dufour JF, Graf R, Humar B, Clavien PA.

Ann Surg. 2020 Feb;271(2):347-355. doi: 10.1097/SLA.0000000000002904.


Alternatively spliced tissue factor levels are elevated in the plasma of patients with chronic liver diseases.

Caversaccio NI, Reina Caro MD, Prince R, Müller M, Lewis CS, Bogdanov VY, Dufour JF, Angelillo-Scherrer A.

Eur J Gastroenterol Hepatol. 2018 Dec;30(12):1470-1475. doi: 10.1097/MEG.0000000000001236.


Prognostic Significance of Controlled Attenuation Parameter in Patients With Compensated Advanced Chronic Liver Disease.

Margini C, Murgia G, Stirnimann G, De Gottardi A, Semmo N, Casu S, Bosch J, Dufour JF, Berzigotti A.

Hepatol Commun. 2018 Jul 24;2(8):929-940. doi: 10.1002/hep4.1201. eCollection 2018 Aug.


Effects of obesity on asthma: immunometabolic links.

Miethe S, Guarino M, Alhamdan F, Simon HU, Renz H, Dufour JF, Potaczek DP, Garn H.

Pol Arch Intern Med. 2018 Aug 31;128(7-8):469-477. doi: 10.20452/pamw.4304. Epub 2018 Jul 27. Review.


Annatto-extracted tocotrienols improve glucose homeostasis and bone properties in high-fat diet-induced type 2 diabetic mice by decreasing the inflammatory response.

Shen CL, Kaur G, Wanders D, Sharma S, Tomison MD, Ramalingam L, Chung E, Moustaid-Moussa N, Mo H, Dufour JM.

Sci Rep. 2018 Jul 27;8(1):11377. doi: 10.1038/s41598-018-29063-9.


Beneficial Effects of Human Anti-Interleukin-15 Antibody in Gluten-Sensitive Rhesus Macaques with Celiac Disease.

Sestak K, Dufour JP, Liu DX, Rout N, Alvarez X, Blanchard J, Faldas A, Laine DJ, Clarke AW, Doyle AG.

Front Immunol. 2018 Jul 11;9:1603. doi: 10.3389/fimmu.2018.01603. eCollection 2018.


Differential contribution of chronic binge alcohol and antiretroviral therapy to metabolic dysregulation in SIV-infected male macaques.

Ford SM Jr, Simon Peter L, Berner P, Cook G, Vande Stouwe C, Dufour J, Bagby G, Nelson S, Molina PE.

Am J Physiol Endocrinol Metab. 2018 Nov 1;315(5):E892-E903. doi: 10.1152/ajpendo.00175.2018. Epub 2018 Jul 24.


Alternative splicing of helicase-like transcription factor (Hltf): Intron retention-dependent activation of immune tolerance at the feto-maternal interface.

Kaur G, Helmer RA, Smith LA, Martinez-Zaguilan R, Dufour JM, Chilton BS.

PLoS One. 2018 Jul 5;13(7):e0200211. doi: 10.1371/journal.pone.0200211. eCollection 2018.


Retraction Note: Liver X receptors constrain tumor development and metastasis dissemination in PTEN-deficient prostate cancer.

Alioui A, Dufour J, Leoni V, Loregger A, Moeton M, Iuliano L, Zerbinati C, Septier A, Val P, Fouache A, Russo V, Volle DH, Lobaccaro JA, Zelcer N, Baron S.

Nat Commun. 2018 Jul 4;9(1):2660. doi: 10.1038/s41467-018-04653-3.


Phase II Studies with Refametinib or Refametinib plus Sorafenib in Patients with RAS-Mutated Hepatocellular Carcinoma.

Lim HY, Merle P, Weiss KH, Yau T, Ross P, Mazzaferro V, Blanc JF, Ma YT, Yen CJ, Kocsis J, Choo SP, Sukeepaisarnjaroen W, Gérolami R, Dufour JF, Gane EJ, Ryoo BY, Peck-Radosavljevic M, Dao T, Yeo W, Lamlertthon W, Thongsawat S, Teufel M, Roth K, Reis D, Childs BH, Krissel H, Llovet JM.

Clin Cancer Res. 2018 Oct 1;24(19):4650-4661. doi: 10.1158/1078-0432.CCR-17-3588. Epub 2018 Jun 27.


Sertoli Cells Engineered to Express Insulin to Lower Blood Glucose in Diabetic Mice.

Kaur G, Thompson LA, Babcock RL, Mueller K, Dufour JM.

DNA Cell Biol. 2018 Aug;37(8):680-690. doi: 10.1089/dna.2017.3937. Epub 2018 Jun 21.


Genetic immune and inflammatory markers associated with diabetes in solid organ transplant recipients.

Quteineh L, Wójtowicz A, Bochud PY, Crettol S, Vandenberghe F, Venetz JP, Manuel O, Golshayan D, Lehmann R, Mueller NJ, Binet I, van Delden C, Steiger J, Mohacsi P, Dufour JF, Soccal PM, Kutalik Z, Marques-Vidal P, Vollenweider P, Recher M, Hess C, Pascual M, Eap CB; Swiss Transplant Cohort Study.

Am J Transplant. 2019 Jan;19(1):238-246. doi: 10.1111/ajt.14971. Epub 2018 Jul 13.


The histidine triad nucleotide-binding protein 2 (HINT-2) positively regulates hepatocellular energy metabolism.

Rajasekaran R, Felser A, Nuoffer JM, Dufour JF, St-Pierre MV.

FASEB J. 2018 Sep;32(9):5143-5161. doi: 10.1096/fj.201701429R. Epub 2018 Apr 18.


Sofosbuvir/velpatasvir for 12 weeks in genotype 1-4 HCV-infected liver transplant recipients.

Agarwal K, Castells L, Müllhaupt B, Rosenberg WMC, McNabb B, Arterburn S, Camus G, McNally J, Stamm LM, Brainard DM, Mani Subramanian G, Mariño Z, Dufour JF, Forns X.

J Hepatol. 2018 Sep;69(3):603-607. doi: 10.1016/j.jhep.2018.05.039. Epub 2018 Jun 8.


Effectiveness of a vacuum lifting system in reducing spinal load during airline baggage handling.

Lu ML, Dufour JS, Weston EB, Marras WS.

Appl Ergon. 2018 Jul;70:247-252. doi: 10.1016/j.apergo.2018.03.006. Epub 2018 Mar 20.


Mycobacterium ulcerans infection (Buruli ulcer) in French Guiana, South America, 1969-2013: an epidemiological study.

Douine M, Gozlan R, Nacher M, Dufour J, Reynaud Y, Elguero E, Combe M, Velvin CJ, Chevillon C, Berlioz-Arthaud A, Labbé S, Sainte-Marie D, Guégan JF, Pradinaud R, Couppié P.

Lancet Planet Health. 2017 May;1(2):e65-e73. doi: 10.1016/S2542-5196(17)30009-8. Epub 2017 May 5.


The contribution of culturomics to the repertoire of isolated human bacterial and archaeal species.

Bilen M, Dufour JC, Lagier JC, Cadoret F, Daoud Z, Dubourg G, Raoult D.

Microbiome. 2018 May 24;6(1):94. doi: 10.1186/s40168-018-0485-5. Review.

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