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Items: 1 to 50 of 208

1.

Outer membrane protein complex as a carrier for malaria transmission blocking antigen Pfs230.

Scaria PV, Rowe CG, Chen BB, Muratova OV, Fischer ER, Barnafo EK, Anderson CF, Zaidi IU, Lambert LE, Lucas BJ, Nahas DD, Narum DL, Duffy PE.

NPJ Vaccines. 2019 Jul 8;4:24. doi: 10.1038/s41541-019-0121-9. eCollection 2019.

2.

Impact of maternally derived antibodies to Plasmodium falciparum Schizont Egress Antigen-1 on the endogenous production of anti-PfSEA-1 in offspring.

Park S, Nixon CE, Pond-Tor S, Kabyemela ER, Fried M, Duffy PE, Kurtis JD, Friedman JF.

Vaccine. 2019 Aug 14;37(35):5044-5050. doi: 10.1016/j.vaccine.2019.06.084. Epub 2019 Jul 6.

3.

Transmission-Blocking Vaccines for Malaria: Time to Talk about Vaccine Introduction.

Coelho CH, Rappuoli R, Hotez PJ, Duffy PE.

Trends Parasitol. 2019 Jul;35(7):483-486. doi: 10.1016/j.pt.2019.04.008. Epub 2019 May 29.

PMID:
31153722
4.

Beyond Blood Smears: Qualification of Plasmodium 18S rRNA as a Biomarker for Controlled Human Malaria Infections.

Seilie AM, Chang M, Hanron AE, Billman ZP, Stone BC, Zhou K, Olsen TM, Daza G, Ortega J, Cruz KR, Smith N, Healy SA, Neal J, Wallis CK, Shelton L, Mankowski TV, Wong-Madden S, Mikolajczak SA, Vaughan AM, Kappe SHI, Fishbaugher M, Betz W, Kennedy M, Hume JCC, Talley AK, Hoffman SL, Chakravarty S, Sim BKL, Richie TL, Wald A, Plowe CV, Lyke KE, Adams M, Fahle GA, Cowan EP, Duffy PE, Kublin JG, Murphy SC.

Am J Trop Med Hyg. 2019 Jun;100(6):1466-1476. doi: 10.4269/ajtmh.19-0094.

5.

Functional Antibodies against Placental Malaria Parasites Are Variant Dependent and Differ by Geographic Region.

Doritchamou J, Teo A, Morrison R, Arora G, Kwan J, Manzella-Lapeira J, Medina-Maldonado S, Langhorne J, Hviid L, Narum DL, Dicko A, Fried M, Duffy PE.

Infect Immun. 2019 Jun 20;87(7). pii: e00865-18. doi: 10.1128/IAI.00865-18. Print 2019 Jul.

PMID:
30988054
6.

Age-dependent increase in antibodies that inhibit Plasmodium falciparum adhesion to a subset of endothelial receptors.

Attaher O, Mahamar A, Swihart B, Barry A, Diarra BS, Kanoute MB, Dembele AB, Keita S, Gaoussou S, Issiaka D, Dicko A, Duffy PE, Fried M.

Malar J. 2019 Apr 11;18(1):128. doi: 10.1186/s12936-019-2764-4.

7.

Longitudinal analysis of gamma delta T cell subsets during malaria infections in Malian adults.

Diallo H, Katile A, Kwan JL, Sissoko MS, Healy SA, Doumbo OK, Duffy PE, Zaidi I.

Malar J. 2019 Mar 12;18(1):69. doi: 10.1186/s12936-019-2702-5.

8.

Chronic helminth infection does not impair immune response to malaria transmission blocking vaccine Pfs230D1-EPA/Alhydrogel® in mice.

Coelho CH, Gazzinelli-Guimaraes PH, Howard J, Barnafo E, Alani NAH, Muratova O, McCormack A, Kelnhofer E, Urban JF Jr, Narum DL, Anderson C, Langhorne J, Nutman TB, Duffy PE.

Vaccine. 2019 Feb 14;37(8):1038-1045. doi: 10.1016/j.vaccine.2019.01.027. Epub 2019 Jan 23.

9.

Malaria vaccine trials in pregnant women: An imperative without precedent.

Healy SA, Fried M, Richie T, Bok K, Little M, August A, Riley L, Swamy GK, Wylie BJ, Menendez C, Muehlenbachs A, Doumbo O, Greenwood B, Billingsley PF, Hoffman SL, Duffy PE.

Vaccine. 2019 Feb 4;37(6):763-770. doi: 10.1016/j.vaccine.2018.12.025. Epub 2019 Jan 6.

PMID:
30621913
10.

Assessment of the impact of manufacturing changes on the physicochemical properties of the recombinant vaccine carrier ExoProtein A.

Burkhardt M, Reiter K, Nguyen V, Suzuki M, Herrera R, Duffy PE, Shimp R Jr, MacDonald NJ, Olano LR, Narum DL.

Vaccine. 2018 Sep 24. pii: S0264-410X(18)31297-0. doi: 10.1016/j.vaccine.2018.09.037. [Epub ahead of print]

PMID:
30262247
11.

Maternally derived antibodies to Schizont Egress Antigen-1 and protection of infants from severe malaria.

Kurtis JD, Raj DK, Michelow IC, Park S, Nixon CE, McDonald EA, Nixon CP, Pond-Tor S, Jha A, Taliano RJ, Kabyemela ER, Friedman JF, Duffy PE, Fried M.

Clin Infect Dis. 2018 Aug 25. doi: 10.1093/cid/ciy728. [Epub ahead of print]

PMID:
30165569
12.

Safety and immunogenicity of Pfs25H-EPA/Alhydrogel, a transmission-blocking vaccine against Plasmodium falciparum: a randomised, double-blind, comparator-controlled, dose-escalation study in healthy Malian adults.

Sagara I, Healy SA, Assadou MH, Gabriel EE, Kone M, Sissoko K, Tembine I, Guindo MA, Doucoure M, Niaré K, Dolo A, Rausch KM, Narum DL, Jones DL, MacDonald NJ, Zhu D, Mohan R, Muratova O, Baber I, Coulibaly MB, Fay MP, Anderson C, Wu Y, Traore SF, Doumbo OK, Duffy PE.

Lancet Infect Dis. 2018 Sep;18(9):969-982. doi: 10.1016/S1473-3099(18)30344-X. Epub 2018 Jul 27.

PMID:
30061051
13.

Antibodies to PfsEGXP, an Early Gametocyte-Enriched Phosphoprotein, Predict Decreased Plasmodium falciparum Gametocyte Density in Humans.

Nixon CP, Nixon CE, Michelow IC, Silva-Viera RA, Colantuono B, Obeidallah AS, Jha A, Dockery D, Raj D, Park S, Duffy PE, Kurtis JD.

J Infect Dis. 2018 Oct 20;218(11):1792-1801. doi: 10.1093/infdis/jiy416.

PMID:
29982707
14.

NK cells inhibit Plasmodium falciparum growth in red blood cells via antibody-dependent cellular cytotoxicity.

Arora G, Hart GT, Manzella-Lapeira J, Doritchamou JY, Narum DL, Thomas LM, Brzostowski J, Rajagopalan S, Doumbo OK, Traore B, Miller LH, Pierce SK, Duffy PE, Crompton PD, Desai SA, Long EO.

Elife. 2018 Jun 26;7. pii: e36806. doi: 10.7554/eLife.36806.

15.

TLR-adjuvanted nanoparticle vaccines differentially influence the quality and longevity of responses to malaria antigen Pfs25.

Thompson EA, Ols S, Miura K, Rausch K, Narum DL, Spångberg M, Juraska M, Wille-Reece U, Weiner A, Howard RF, Long CA, Duffy PE, Johnston L, O'Neil CP, Loré K.

JCI Insight. 2018 May 17;3(10). pii: 120692. doi: 10.1172/jci.insight.120692. eCollection 2018 May 17.

16.

Sulfamethoxazole Levels in HIV-Exposed Uninfected Ugandan Children.

Kasule J, Gabriel EE, Anok A, Neal J, Eastman RT, Penzak S, Newell K, Serwadda D, Duffy PE, Reynolds SJ, Hobbs CV.

Am J Trop Med Hyg. 2018 Jun;98(6):1718-1721. doi: 10.4269/ajtmh.17-0933. Epub 2018 Apr 19.

17.

Development of a bivalent conjugate vaccine candidate against malaria transmission and typhoid fever.

An SJ, Scaria PV, Chen B, Barnafo E, Muratova O, Anderson C, Lambert L, Chae MH, Yang JS, Duffy PE.

Vaccine. 2018 May 17;36(21):2978-2984. doi: 10.1016/j.vaccine.2018.04.035. Epub 2018 Apr 20.

PMID:
29681410
18.

Seroepidemiology of helminths and the association with severe malaria among infants and young children in Tanzania.

Kwan JL, Seitz AE, Fried M, Lee KL, Metenou S, Morrison R, Kabyemela E, Nutman TB, Prevots DR, Duffy PE.

PLoS Negl Trop Dis. 2018 Mar 26;12(3):e0006345. doi: 10.1371/journal.pntd.0006345. eCollection 2018 Mar.

19.

Antibody levels to recombinant VAR2CSA domains vary with Plasmodium falciparum parasitaemia, gestational age, and gravidity, but do not predict pregnancy outcomes.

Fried M, Kurtis JD, Swihart B, Morrison R, Pond-Tor S, Barry A, Sidibe Y, Keita S, Mahamar A, Andemel N, Attaher O, Dembele AB, Cisse KB, Diarra BS, Kanoute MB, Narum DL, Dicko A, Duffy PE.

Malar J. 2018 Mar 9;17(1):106. doi: 10.1186/s12936-018-2258-9.

20.

Advances in malaria vaccine development: report from the 2017 malaria vaccine symposium.

Coelho CH, Doritchamou JYA, Zaidi I, Duffy PE.

NPJ Vaccines. 2017 Nov 30;2:34. doi: 10.1038/s41541-017-0035-3. eCollection 2017.

21.

Response to Comment on "γδ T Cells Are Required for the Induction of Sterile Immunity during Irradiated Sporozoite Vaccinations".

Zaidi I, Duffy PE.

J Immunol. 2018 Mar 1;200(5):1533-1534. doi: 10.4049/jimmunol.1701799. No abstract available.

22.

Identification of a Novel CD8 T Cell Epitope Derived from Plasmodium berghei Protective Liver-Stage Antigen.

Pichugin A, Zarling S, Perazzo L, Duffy PE, Ploegh HL, Krzych U.

Front Immunol. 2018 Jan 29;9:91. doi: 10.3389/fimmu.2018.00091. eCollection 2018.

23.

Protein-protein conjugate nanoparticles for malaria antigen delivery and enhanced immunogenicity.

Scaria PV, Chen B, Rowe CG, Jones DS, Barnafo E, Fischer ER, Anderson C, MacDonald NJ, Lambert L, Rausch KM, Narum DL, Duffy PE.

PLoS One. 2017 Dec 27;12(12):e0190312. doi: 10.1371/journal.pone.0190312. eCollection 2017.

24.

Developing a novel risk prediction model for severe malarial anemia.

Brickley EB, Kabyemela E, Kurtis JD, Fried M, Wood AM, Duffy PE.

Glob Health Epidemiol Genom. 2017 Sep 11;2:e14. doi: 10.1017/gheg.2017.8. eCollection 2017.

25.

Prevalence of Asymptomatic Parasitemia and Gametocytemia in HIV-Infected Children on Differing Antiretroviral Therapy.

Hobbs CV, Gabriel EE, Kamthunzi P, Tegha G, Tauzie J, Li Y, Ilmet T, Artimovich E, Neal J, Hall T, Parikh S, Kirmse B, Jean-Philippe P, Chen J, Prescott WR, Palumbo P, Duffy PE, Borkowsky W, For The P S Study Team.

Am J Trop Med Hyg. 2018 Jan;98(1):67-70. doi: 10.4269/ajtmh.17-0462.

26.

Hemoglobin variants shape the distribution of malaria parasites in human populations and their transmission potential.

Gonçalves BP, Sagara I, Coulibaly M, Wu Y, Assadou MH, Guindo A, Ellis RD, Diakite M, Gabriel E, Prevots DR, Doumbo OK, Duffy PE.

Sci Rep. 2017 Oct 27;7(1):14267. doi: 10.1038/s41598-017-14627-y.

27.

γδ T Cells Are Required for the Induction of Sterile Immunity during Irradiated Sporozoite Vaccinations.

Zaidi I, Diallo H, Conteh S, Robbins Y, Kolasny J, Orr-Gonzalez S, Carter D, Butler B, Lambert L, Brickley E, Morrison R, Sissoko M, Healy SA, Sim BKL, Doumbo OK, Hoffman SL, Duffy PE.

J Immunol. 2017 Dec 1;199(11):3781-3788. doi: 10.4049/jimmunol.1700314. Epub 2017 Oct 27.

28.

Host factors that modify Plasmodium falciparum adhesion to endothelial receptors.

Mahamar A, Attaher O, Swihart B, Barry A, Diarra BS, Kanoute MB, Cisse KB, Dembele AB, Keita S, Gamain B, Gaoussou S, Issiaka D, Dicko A, Duffy PE, Fried M.

Sci Rep. 2017 Oct 24;7(1):13872. doi: 10.1038/s41598-017-14351-7.

29.

Systemic Inflammatory Response to Malaria During Pregnancy Is Associated With Pregnancy Loss and Preterm Delivery.

Fried M, Kurtis JD, Swihart B, Pond-Tor S, Barry A, Sidibe Y, Gaoussou S, Traore M, Keita S, Mahamar A, Attaher O, Dembele AB, Cisse KB, Diarra BS, Kanoute MB, Dicko A, Duffy PE.

Clin Infect Dis. 2017 Oct 30;65(10):1729-1735. doi: 10.1093/cid/cix623.

30.

Malaria in pregnancy: the relevance of animal models for vaccine development.

Doritchamou J, Teo A, Fried M, Duffy PE.

Lab Anim (NY). 2017 Oct 6;46(10):388-398. doi: 10.1038/laban.1349. Review.

PMID:
28984865
31.

Role of Activins in Hepcidin Regulation during Malaria.

Spottiswoode N, Armitage AE, Williams AR, Fyfe AJ, Biswas S, Hodgson SH, Llewellyn D, Choudhary P, Draper SJ, Duffy PE, Drakesmith H.

Infect Immun. 2017 Nov 17;85(12). pii: e00191-17. doi: 10.1128/IAI.00191-17. Print 2017 Dec.

32.

A malaria vaccine protects Aotus monkeys against virulent Plasmodium falciparum infection.

Srinivasan P, Baldeviano GC, Miura K, Diouf A, Ventocilla JA, Leiva KP, Lugo-Roman L, Lucas C, Orr-Gonzalez S, Zhu D, Villasante E, Soisson L, Narum DL, Pierce SK, Long CA, Diggs C, Duffy PE, Lescano AG, Miller LH.

NPJ Vaccines. 2017;2. pii: 14. doi: 10.1038/s41541-017-0015-7. Epub 2017 May 22.

33.

Optimizing Direct Membrane and Direct Skin Feeding Assays for Plasmodium falciparum Transmission-Blocking Vaccine Trials in Bancoumana, Mali.

Coulibaly MB, Gabriel EE, Sinaba Y, Sylla D, Sacko A, Sylla L, Coulibaly B, Hume JCC, Baber I, Assadou MH, Sagara I, Wu Y, Healy SA, Doumbo O, Traore SF, Duffy PE.

Am J Trop Med Hyg. 2017 Sep;97(3):719-725. doi: 10.4269/ajtmh.16-1000. Epub 2017 Jul 19.

34.

Effect of seasonal malaria chemoprevention on the acquisition of antibodies to Plasmodium falciparum antigens in Ouelessebougou, Mali.

Mahamar A, Issiaka D, Barry A, Attaher O, Dembele AB, Traore T, Sissoko A, Keita S, Diarra BS, Narum DL, Duffy PE, Dicko A, Fried M.

Malar J. 2017 Jul 18;16(1):289. doi: 10.1186/s12936-017-1935-4.

35.

Malaria Infection and Gametocyte Carriage Rates in Preparation for Transmission Blocking Vaccine Trials in Bancoumana, Mali.

Assadou MH, Sagara I, Healy SA, Guindo MA, Kone M, Sanogo S, Doucoure M, Keita S, Ellis RD, Wu Y, Omaswa F, Duffy PE, Doumbo OK.

Am J Trop Med Hyg. 2017 Jul;97(1):183-187. doi: 10.4269/ajtmh.15-0845.

36.

A Malaria-Resistant Phenotype with Immunological Correlates in a Tanzanian Birth Cohort Exposed to Intense Malaria Transmission.

Nash SD, Prevots DR, Kabyemela E, Khasa YP, Lee KL, Fried M, Duffy PE.

Am J Trop Med Hyg. 2017 May;96(5):1190-1196. doi: 10.4269/ajtmh.16-0554.

37.

Accelerated and long term stability study of Pfs25-EPA conjugates adjuvanted with Alhydrogel®.

Zhu D, Wu Y, McClellan H, Dai W, Rausch K, Jones D, Aebig J, Barnafo E, Butler B, Lambert L, Narum DL, Duffy PE.

Vaccine. 2017 May 31;35(24):3232-3238. doi: 10.1016/j.vaccine.2017.04.067. Epub 2017 May 4.

38.

Identification of Protective B-Cell Epitopes within the Novel Malaria Vaccine Candidate Plasmodium falciparum Schizont Egress Antigen 1.

Nixon CE, Park S, Pond-Tor S, Raj D, Lambert LE, Orr-Gonzalez S, Barnafo EK, Rausch KM, Friedman JF, Fried M, Duffy PE, Kurtis JD.

Clin Vaccine Immunol. 2017 Jul 5;24(7). pii: e00068-17. doi: 10.1128/CVI.00068-17. Print 2017 Jul.

39.

Maternal Microchimerism Predicts Increased Infection but Decreased Disease due to Plasmodium falciparum During Early Childhood.

Harrington WE, Kanaan SB, Muehlenbachs A, Morrison R, Stevenson P, Fried M, Duffy PE, Nelson JL.

J Infect Dis. 2017 May 1;215(9):1445-1451. doi: 10.1093/infdis/jix129.

40.

Safety and efficacy of PfSPZ Vaccine against Plasmodium falciparum via direct venous inoculation in healthy malaria-exposed adults in Mali: a randomised, double-blind phase 1 trial.

Sissoko MS, Healy SA, Katile A, Omaswa F, Zaidi I, Gabriel EE, Kamate B, Samake Y, Guindo MA, Dolo A, Niangaly A, Niaré K, Zeguime A, Sissoko K, Diallo H, Thera I, Ding K, Fay MP, O'Connell EM, Nutman TB, Wong-Madden S, Murshedkar T, Ruben AJ, Li M, Abebe Y, Manoj A, Gunasekera A, Chakravarty S, Sim BKL, Billingsley PF, James ER, Walther M, Richie TL, Hoffman SL, Doumbo O, Duffy PE.

Lancet Infect Dis. 2017 May;17(5):498-509. doi: 10.1016/S1473-3099(17)30104-4. Epub 2017 Feb 16.

PMID:
28216244
41.

Malaria during Pregnancy.

Fried M, Duffy PE.

Cold Spring Harb Perspect Med. 2017 Jun 1;7(6). pii: a025551. doi: 10.1101/cshperspect.a025551. Review.

42.

Antibody-independent mechanisms regulate the establishment of chronic Plasmodium infection.

Brugat T, Reid AJ, Lin J, Cunningham D, Tumwine I, Kushinga G, McLaughlin S, Spence P, Böhme U, Sanders M, Conteh S, Bushell E, Metcalf T, Billker O, Duffy PE, Newbold C, Berriman M, Langhorne J.

Nat Microbiol. 2017 Feb 6;2:16276. doi: 10.1038/nmicrobiol.2016.276.

43.

Grammomys surdaster, the Natural Host for Plasmodium berghei Parasites, as a Model to Study Whole-Organism Vaccines Against Malaria.

Conteh S, Anderson C, Lambert L, Orr-Gonzalez S, Herrod J, Robbins YL, Carter D, Karhemere SBS, Pyana P, Büscher P, Duffy PE.

Am J Trop Med Hyg. 2017 Apr;96(4):835-841. doi: 10.4269/ajtmh.16-0745. Epub 2017 Jan 23.

44.

Trimethoprim-Sulfamethoxazole Prophylaxis During Live Malaria Sporozoite Immunization Induces Long-Lived, Homologous, and Heterologous Protective Immunity Against Sporozoite Challenge.

Hobbs CV, Anderson C, Neal J, Sahu T, Conteh S, Voza T, Langhorne J, Borkowsky W, Duffy PE.

J Infect Dis. 2017 Jan 1;215(1):122-130. doi: 10.1093/infdis/jiw482. Epub 2016 Oct 17.

45.

Malaria in HIV-Infected Children Receiving HIV Protease-Inhibitor- Compared with Non-Nucleoside Reverse Transcriptase Inhibitor-Based Antiretroviral Therapy, IMPAACT P1068s, Substudy to P1060.

Hobbs CV, Gabriel EE, Kamthunzi P, Tegha G, Tauzie J, Petzold E, Barlow-Mosha L, Chi BH, Li Y, Ilmet T, Kirmse B, Neal J, Parikh S, Deygoo N, Jean Philippe P, Mofenson L, Prescott W, Chen J, Musoke P, Palumbo P, Duffy PE, Borkowsky W; P1068s Study Team.

PLoS One. 2016 Dec 9;11(12):e0165140. doi: 10.1371/journal.pone.0165140. eCollection 2016.

46.

Utilizing direct skin feeding assays for development of vaccines that interrupt malaria transmission: A systematic review of methods and case study.

Brickley EB, Coulibaly M, Gabriel EE, Healy SA, Hume JCC, Sagara I, Traore SF, Doumbo O, Duffy PE.

Vaccine. 2016 Nov 21;34(48):5863-5870. doi: 10.1016/j.vaccine.2016.10.027. Epub 2016 Oct 24. Review.

47.

Correction: Identification of Novel Pre-Erythrocytic Malaria Antigen Candidates for Combination Vaccines with Circumsporozoite Protein.

Speake C, Pichugin A, Sahu T, Malkov V, Morrison R, Pei Y, Juompan L, Milman N, Zarling S, Anderson C, MacDonald NJ, Wong-Madden S, Wendler J, Ishizuka A, MacMillen ZW, Garcia V, Kappe SH, Krzych U, Duffy PE.

PLoS One. 2016 Oct 20;11(10):e0165489. doi: 10.1371/journal.pone.0165489. eCollection 2016.

48.

Safety and Immunogenicity of Pfs25-EPA/Alhydrogel®, a Transmission Blocking Vaccine against Plasmodium falciparum: An Open Label Study in Malaria Naïve Adults.

Talaat KR, Ellis RD, Hurd J, Hentrich A, Gabriel E, Hynes NA, Rausch KM, Zhu D, Muratova O, Herrera R, Anderson C, Jones D, Aebig J, Brockley S, MacDonald NJ, Wang X, Fay MP, Healy SA, Durbin AP, Narum DL, Wu Y, Duffy PE.

PLoS One. 2016 Oct 17;11(10):e0163144. doi: 10.1371/journal.pone.0163144. eCollection 2016.

49.

Heterologous Infection of Pregnant Mice Induces Low Birth Weight and Modifies Offspring Susceptibility to Malaria.

Sharma A, Conteh S, Langhorne J, Duffy PE.

PLoS One. 2016 Jul 28;11(7):e0160120. doi: 10.1371/journal.pone.0160120. eCollection 2016.

50.

Identification of Novel Pre-Erythrocytic Malaria Antigen Candidates for Combination Vaccines with Circumsporozoite Protein.

Speake C, Pichugin A, Sahu T, Malkov V, Morrison R, Pei Y, Juompan L, Milman N, Zarling S, Anderson C, Wong-Madden S, Wendler J, Ishizuka A, MacMillen ZW, Garcia V, Kappe SH, Krzych U, Duffy PE.

PLoS One. 2016 Jul 19;11(7):e0159449. doi: 10.1371/journal.pone.0159449. eCollection 2016. Erratum in: PLoS One. 2016 Oct 20;11(10 ):e0165489.

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