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Discovery of MK-8719, A Potent O-GlcNAcase Inhibitor as a Potential Treatment for Tauopathies.

Selnick H, Hess JF, Tang C, Liu K, Schachter J, Ballard JE, Marcus JN, Klein DJ, Wang X, Pearson M, Savage MJ, Kaul R, Li T, Vocadlo DJ, Zhou Y, Zhu Y, Mu C, Wang Y, Wei Z, Bai C, Duffy JL, McEachern EJ.

J Med Chem. 2019 Sep 5. doi: 10.1021/acs.jmedchem.9b01090. [Epub ahead of print]


Rupture of a Type B Aortic Dissection in a Postpartum Patient with Marfan Syndrome.

Patberg E, Duffy J, Hameed AB.

AJP Rep. 2019 Jul;9(3):e256-e261. doi: 10.1055/s-0039-1692712. Epub 2019 Aug 20.


Classifying attentional vulnerability to total sleep deprivation using baseline features of Psychomotor Vigilance Test performance.

Chua EC, Sullivan JP, Duffy JF, Klerman EB, Lockley SW, Kristal BS, Czeisler CA, Gooley JJ.

Sci Rep. 2019 Aug 20;9(1):12102. doi: 10.1038/s41598-019-48280-4.


Clinical and neuroimaging characteristics of clinically unclassifiable primary progressive aphasia.

Utianski RL, Botha H, Martin PR, Schwarz CG, Duffy JR, Clark HM, Machulda MM, Butts AM, Lowe VJ, Jack CR Jr, Senjem ML, Spychalla AJ, Whitwell JL, Josephs KA.

Brain Lang. 2019 Oct;197:104676. doi: 10.1016/j.bandl.2019.104676. Epub 2019 Aug 13.


An Evaluation of the Progressive Supranuclear Palsy Speech/Language Variant.

Whitwell JL, Stevens CA, Duffy JR, Clark HM, Machulda MM, Strand EA, Martin PR, Utianski RL, Botha H, Spychalla AJ, Senjem ML, Schwarz CG, Jack CR Jr, Ali F, Hassan A, Josephs KA.

Mov Disord Clin Pract. 2019 May 29;6(6):452-461. doi: 10.1002/mdc3.12796. eCollection 2019 Jul.


Methodological decisions influence the identification of potential core outcomes in studies related to pre-eclampsia: an analysis informing the development of  recommendations for future core outcome set developers.

Duffy J, Hirsch M, Ziebland S, McManus RJ; International Collaboration to Harmonise Outcomes in Pre-eclampsia (iHOPE).

BJOG. 2019 Jul 29. doi: 10.1111/1471-0528.15892. [Epub ahead of print]


Ileostomy after intestinal transplantation: the first in depth report on techniques, complications, and outcomes.

Dumronggittigule W, Venick RS, Dubray BJ Jr, Cheng EC, Duffy JP, Marcus EA, Busuttil RW, Farmer DG.

Transplantation. 2019 Jul 15. doi: 10.1097/TP.0000000000002879. [Epub ahead of print]


Structural characterization of life-extending Caenorhabditis elegans Lipid Binding Protein 8.

Tillman MC, Khadka M, Duffy J, Wang MC, Ortlund EA.

Sci Rep. 2019 Jul 10;9(1):9966. doi: 10.1038/s41598-019-46230-8.


A core outcome set for studies investigating the management of selective fetal growth restriction in twins.

Townsend R, Duffy JMN, Sileo F, Perry H, Ganzevoort W, Reed K, Baschat AA, Deprest J, Gratacos E, Hecher K, Lewi L, Lopriore E, Oepkes D, Papageorghiou A, Gordijn SJ, Khalil A; International Collaboration to Harmonise Outcomes for Selective Fetal Growth Restriction (CHOOSE-FGR).

Ultrasound Obstet Gynecol. 2019 Jul 4. doi: 10.1002/uog.20388. [Epub ahead of print]


Use of progression criteria to support monitoring and commissioning decision making of public health services: lessons from Better Start Bradford.

Bryant M, Dharni N, Dickerson J, Willan K, McEachan R, Duffy J, Howell M.

BMC Public Health. 2019 Jun 27;19(1):835. doi: 10.1186/s12889-019-7149-7.


Comparison of Outcomes with Semi-mechanical and Circular Stapled Intrathoracic Esophagogastric Anastomosis following Esophagectomy.

Yanni F, Singh P, Tewari N, Parsons SL, Catton JA, Duffy J, Welch NT, Vohra RS.

World J Surg. 2019 Oct;43(10):2483-2489. doi: 10.1007/s00268-019-05057-0.


Progressive agrammatic aphasia without apraxia of speech as a distinct syndrome.

Tetzloff KA, Duffy JR, Clark HM, Utianski RL, Strand EA, Machulda MM, Botha H, Martin PR, Schwarz CG, Senjem ML, Reid RI, Gunter JL, Spychalla AJ, Knopman DS, Petersen RC, Jack CR, Lowe VJ, Josephs KA, Whitwell JL.

Brain. 2019 Aug 1;142(8):2466-2482. doi: 10.1093/brain/awz157.


The use of natural language processing to identify Tdap-related local reactions at five health care systems in the Vaccine Safety Datalink.

Zheng C, Yu W, Xie F, Chen W, Mercado C, Sy LS, Qian L, Glenn S, Lee G, Tseng HF, Duffy J, Jackson LA, Daley MF, Crane B, McLean HQ, Jacobsen SJ.

Int J Med Inform. 2019 Jul;127:27-34. doi: 10.1016/j.ijmedinf.2019.04.009. Epub 2019 Apr 13.


A non-discriminatory response to disability related problem behaviour at Australian universities.

Dickson E, Duffy J.

Int J Law Psychiatry. 2019 May - Jun;64:129-136. doi: 10.1016/j.ijlp.2019.03.004. Epub 2019 Mar 29. Review.


Inconsistent outcome reporting in large neonatal trials: a systematic review.

Webbe JWH, Ali S, Sakonidou S, Webbe T, Duffy JMN, Brunton G, Modi N, Gale C; COIN Project Steering Committee.

Arch Dis Child Fetal Neonatal Ed. 2019 May 13. pii: fetalneonatal-2019-316823. doi: 10.1136/archdischild-2019-316823. [Epub ahead of print]


Increasing value and reducing research waste in obstetrics: towards woman-centred research.

Townsend R, Duffy JMN, Khalil A.

Ultrasound Obstet Gynecol. 2019 Apr 13. doi: 10.1002/uog.20294. [Epub ahead of print]


Chronotype Genetic Variant in PER2 is Associated with Intrinsic Circadian Period in Humans.

Chang AM, Duffy JF, Buxton OM, Lane JM, Aeschbach D, Anderson C, Bjonnes AC, Cain SW, Cohen DA, Frayling TM, Gooley JJ, Jones SE, Klerman EB, Lockley SW, Munch M, Rajaratnam SMW, Rueger M, Rutter MK, Santhi N, Scheuermaier K, Van Reen E, Weedon MN, Czeisler CA, Scheer FAJL, Saxena R.

Sci Rep. 2019 Mar 29;9(1):5350. doi: 10.1038/s41598-019-41712-1.


A protocol developing, disseminating and implementing a core outcome set for infertility.

Duffy JMN, Bhattacharya S, Curtis C, Evers JLH, Farquharson RG, Franik S, Khalaf Y, Legro RS, Lensen S, Mol BW, Niederberger C, Ng EHY, Repping S, Strandell A, Torrance HL, Vail A, van Wely M, Vuong NL, Wang AY, Wang R, Wilkinson J, Youssef MA, Farquhar CM; COMMIT: Core Outcomes Measures for Infertility Trials.

Hum Reprod Open. 2018 Jun 15;2018(3):hoy007. doi: 10.1093/hropen/hoy007. eCollection 2018. Review.


Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.

Baragaña B, Forte B, Choi R, Nakazawa Hewitt S, Bueren-Calabuig JA, Pisco JP, Peet C, Dranow DM, Robinson DA, Jansen C, Norcross NR, Vinayak S, Anderson M, Brooks CF, Cooper CA, Damerow S, Delves M, Dowers K, Duffy J, Edwards TE, Hallyburton I, Horst BG, Hulverson MA, Ferguson L, Jiménez-Díaz MB, Jumani RS, Lorimer DD, Love MS, Maher S, Matthews H, McNamara CW, Miller P, O'Neill S, Ojo KK, Osuna-Cabello M, Pinto E, Post J, Riley J, Rottmann M, Sanz LM, Scullion P, Sharma A, Shepherd SM, Shishikura Y, Simeons FRC, Stebbins EE, Stojanovski L, Straschil U, Tamaki FK, Tamjar J, Torrie LS, Vantaux A, Witkowski B, Wittlin S, Yogavel M, Zuccotto F, Angulo-Barturen I, Sinden R, Baum J, Gamo FJ, Mäser P, Kyle DE, Winzeler EA, Myler PJ, Wyatt PG, Floyd D, Matthews D, Sharma A, Striepen B, Huston CD, Gray DW, Fairlamb AH, Pisliakov AV, Walpole C, Read KD, Van Voorhis WC, Gilbert IH.

Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):7015-7020. doi: 10.1073/pnas.1814685116. Epub 2019 Mar 20.


Prominent auditory deficits in primary progressive aphasia: A case study.

Utianski RL, Duffy JR, Clark HM, Machulda MM, Dickson DW, Whitwell JL, Josephs KA.

Cortex. 2019 Aug;117:396-406. doi: 10.1016/j.cortex.2019.01.021. Epub 2019 Feb 21.


Association of a Delayed Cord-Clamping Protocol With Hyperbilirubinemia in Term Neonates.

Yang S, Duffy JY, Johnston R, Fall C, Fitzmaurice LE.

Obstet Gynecol. 2019 Apr;133(4):754-761. doi: 10.1097/AOG.0000000000003172.


Correction: Popular interest in vertebrates does not reflect extinction risk and is associated with bias in conservation investment.

Davies T, Cowley A, Bennie J, Leyshon C, Inger R, Carter H, Robinson B, Duffy JP, Casalegno S, Lambert G, Gaston K.

PLoS One. 2019 Feb 6;14(2):e0212101. doi: 10.1371/journal.pone.0212101. eCollection 2019.


Reefs need richness.

Duffy JE.

Nat Ecol Evol. 2019 Feb;3(2):149-150. doi: 10.1038/s41559-018-0784-z. No abstract available.


What outcomes should researchers select, collect and report in pre-eclampsia research? A qualitative study exploring the views of women with lived experience of pre-eclampsia.

Duffy J, Thompson T, Hinton L, Salinas M, McManus RJ, Ziebland S; International Collaboration to Harmonise Outcomes in Pre-eclampsia (iHOPE) Qualitative Research Group.

BJOG. 2019 Apr;126(5):637-646. doi: 10.1111/1471-0528.15616. Epub 2019 Feb 24.


Nontraumatic rupture of the costal margin: a single-center experience.

Mary Parks R, Jadoon M, Duffy J.

Asian Cardiovasc Thorac Ann. 2019 Feb;27(2):105-109. doi: 10.1177/0218492318823367. Epub 2019 Jan 15.


The influence of β-amyloid on [18F]AV-1451 in semantic variant of primary progressive aphasia.

Whitwell JL, Martin PR, Duffy JR, Clark HM, Machulda MM, Schwarz CG, Weigand SD, Sintini I, Senjem ML, Ertekin-Taner N, Botha H, Utianski RL, Graff-Radford J, Jones DT, Boeve BF, Knopman DS, Petersen RC, Jack CR Jr, Lowe VJ, Josephs KA.

Neurology. 2019 Feb 12;92(7):e710-e722. doi: 10.1212/WNL.0000000000006913. Epub 2019 Jan 11.


Study protocol: developing, disseminating, and implementing a core outcome set for selective fetal growth restriction in monochorionic twin pregnancies.

Khalil A, Duffy JMN, Perry H, Ganzevoort W, Reed K, Baschat AA, Deprest J, Gratacos E, Hecher K, Lewi L, Lopriore E, Oepkes D, Papageorghiou A, Gordijn SJ; International Collaboration to Harmonise Outcomes for Selective Fetal Growth Restriction (CHOOSE-FGR).

Trials. 2019 Jan 9;20(1):35. doi: 10.1186/s13063-018-3153-y.


Differentiation of fentanyl analogues by low-field NMR spectroscopy.

Duffy J, Urbas A, Niemitz M, Lippa K, Marginean I.

Anal Chim Acta. 2019 Feb 21;1049:161-169. doi: 10.1016/j.aca.2018.12.014. Epub 2018 Dec 17.


Rapid rate on quasi-speech tasks in the semantic variant of primary progressive aphasia: A non-motor phenomenon?

Utianski RL, Botha H, Duffy JR, Clark HM, Martin PR, Butts AM, Machulda MM, Whitwell JL, Josephs KA.

J Acoust Soc Am. 2018 Dec;144(6):3364. doi: 10.1121/1.5082210.


Evaluation of 4-Amino 2-Anilinoquinazolines against Plasmodium and Other Apicomplexan Parasites In Vitro and in a P. falciparum Humanized NOD-scid IL2Rγnull Mouse Model of Malaria.

Gilson PR, Nguyen W, Poole WA, Teixeira JE, Thompson JK, Guo K, Stewart RJ, Ashton TD, White KL, Sanz LM, Gamo FJ, Charman SA, Wittlin S, Duffy J, Tonkin CJ, Tham WH, Crabb BS, Cooke BM, Huston CD, Cowman AF, Sleebs BE.

Antimicrob Agents Chemother. 2019 Feb 26;63(3). pii: e01804-18. doi: 10.1128/AAC.01804-18. Print 2019 Mar.


Phase Shifts to a Moderate Intensity Light Exposure in Older Adults: A Preliminary Report.

Scheuermaier KD, Lee JH, Duffy JF.

J Biol Rhythms. 2019 Feb;34(1):98-104. doi: 10.1177/0748730418818655. Epub 2018 Dec 17.


Standardized outcome measures for pregnancy and childbirth, an ICHOM proposal.

Nijagal MA, Wissig S, Stowell C, Olson E, Amer-Wahlin I, Bonsel G, Brooks A, Coleman M, Devi Karalasingam S, Duffy JMN, Flanagan T, Gebhardt S, Greene ME, Groenendaal F, R Jeganathan JR, Kowaliw T, Lamain-de-Ruiter M, Main E, Owens M, Petersen R, Reiss I, Sakala C, Speciale AM, Thompson R, Okunade O, Franx A.

BMC Health Serv Res. 2018 Dec 11;18(1):953. doi: 10.1186/s12913-018-3732-3.


Core outcome set for research studies evaluating treatments for twin-twin transfusion syndrome.

Perry H, Duffy JMN, Reed K, Baschat A, Deprest J, Hecher K, Lewi L, Lopriore E, Oepkes D, Khalil A; International Collaboration to Harmonise Outcomes for Twin-Twin Transfusion Syndrome (CHOOSE).

Ultrasound Obstet Gynecol. 2019 Aug;54(2):255-261. doi: 10.1002/uog.20183. Epub 2019 Jul 11.


Clinical Progression in Four Cases of Primary Progressive Apraxia of Speech.

Utianski RL, Duffy JR, Clark HM, Strand EA, Boland SM, Machulda MM, Whitwell JL, Josephs KA.

Am J Speech Lang Pathol. 2018 Nov 21;27(4):1303-1318. doi: 10.1044/2018_AJSLP-17-0227.


Personalised Ecology.

Gaston KJ, Soga M, Duffy JP, Garrett JK, Gaston S, Cox DTC.

Trends Ecol Evol. 2018 Dec;33(12):916-925. doi: 10.1016/j.tree.2018.09.012. Epub 2018 Oct 24.


Vaccination and risk of lone atrial fibrillation in the active component United States military.

McNeil MM, Duderstadt SK, Sabatier JF, Ma GG, Duffy J.

Hum Vaccin Immunother. 2019;15(3):669-676. doi: 10.1080/21645515.2018.1549453. Epub 2019 Jan 8.


A systematic review on reporting outcomes and outcome measures in trials on synthetic mesh procedures for pelvic organ prolapse: Urgent action is needed to improve quality of research.

de Mattos Lourenco TR, Pergialiotis V, Duffy JMN, Durnea C, Elfituri A, Haddad JM, Betschart C, Falconi G, Doumouchtsis SK.

Neurourol Urodyn. 2019 Feb;38(2):509-524. doi: 10.1002/nau.23871. Epub 2018 Nov 15. Review.


Optimization of Preclinical Metabolism for Somatostatin Receptor Subtype 5-Selective Antagonists.

Liu W, Hussain Z, Zang Y, Sweis RF, Romero FA, Finke PE, Moningka R, Bao J, Plotkin MA, Shang J, Dingley KH, Salituro G, Murphy BA, Howard AD, Ujjainwalla F, Wood HB, Duffy JL.

ACS Med Chem Lett. 2018 Oct 5;9(11):1088-1093. doi: 10.1021/acsmedchemlett.8b00306. eCollection 2018 Nov 8.


Discovery and Pharmacology of a Novel Somatostatin Subtype 5 (SSTR5) Antagonist: Synergy with DPP-4 Inhibition.

Liu W, Shao PP, Liang GB, Bawiec J, He J, Aster SD, Wu M, Chicchi G, Wang J, Tsao KL, Shang J, Salituro G, Zhou YP, Li C, Akiyama TE, Metzger DE, Murphy BA, Howard AD, Weber AE, Duffy JL.

ACS Med Chem Lett. 2018 Sep 12;9(11):1082-1087. doi: 10.1021/acsmedchemlett.8b00305. eCollection 2018 Nov 8.


Human Resting Energy Expenditure Varies with Circadian Phase.

Zitting KM, Vujovic N, Yuan RK, Isherwood CM, Medina JE, Wang W, Buxton OM, Williams JS, Czeisler CA, Duffy JF.

Curr Biol. 2018 Nov 19;28(22):3685-3690.e3. doi: 10.1016/j.cub.2018.10.005. Epub 2018 Nov 8.


Lobectomy vs. segmentectomy. A propensity score matched comparison of outcomes.

Roman M, Labbouz S, Valtzoglou V, Ciesla A, Hawari M, Addae-Boateng E, Thorpe JA, Duffy JP, Majewski A.

Eur J Surg Oncol. 2019 May;45(5):845-850. doi: 10.1016/j.ejso.2018.10.534. Epub 2018 Nov 1.


Chewing gum improves postoperative recovery of gastrointestinal function after caesarean delivery: a systematic review and meta-analysis of randomized trials.

Illingworth BJG, Duffy JMN.

J Matern Fetal Neonatal Med. 2018 Nov 20:1. doi: 10.1080/14767058.2018.1543394. [Epub ahead of print] No abstract available.


Patterns of Neuropsychological Dysfunction and Cortical Volume Changes in Logopenic Aphasia.

Owens TE, Machulda MM, Duffy JR, Strand EA, Clark HM, Boland S, Martin PR, Lowe VJ, Jack CR, Whitwell JL, Josephs KA.

J Alzheimers Dis. 2018;66(3):1015-1025. doi: 10.3233/JAD-171175.


Erratum for Brunschwig et al., "UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria".

Brunschwig C, Lawrence N, Taylor D, Abay E, Njoroge M, Basarab GS, Le Manach C, Paquet T, Gonzàlez Cabrera D, Nchinda AT, de Kock C, Wiesner L, Denti P, Waterson D, Blasco B, Leroy D, Witty MJ, Donini C, Duffy J, Wittlin S, White KL, Charman SA, Jiménez-Díaz MB, Angulo-Barturen I, Herreros E, Gamo FJ, Rochford R, Mancama D, Coetzer TL, van der Watt ME, Reader J, Birkholtz LM, Marsh KC, Solapure SM, Burke JE, McPhail JA, Vanaerschot M, Fidock DA, Fish PV, Siegl P, Smith DA, Wirjanata G, Noviyanti R, Price RN, Marfurt J, Silue KD, Street LJ, Chibale K.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e01941-18. doi: 10.1128/AAC.01941-18. Print 2018 Nov. No abstract available.


A systematic review of outcome and outcome-measure reporting in randomised trials evaluating surgical interventions for anterior-compartment vaginal prolapse: a call to action to develop a core outcome set.

Durnea CM, Pergialiotis V, Duffy JMN, Bergstrom L, Elfituri A, Doumouchtsis SK; CHORUS, an International Collaboration for Harmonising Outcomes, Research and Standards in Urogynaecology and Women’s Health.

Int Urogynecol J. 2018 Dec;29(12):1727-1745. doi: 10.1007/s00192-018-3781-5. Epub 2018 Oct 22.


Collagen fibre orientation and dispersion govern ultimate tensile strength, stiffness and the fatigue performance of bovine pericardium.

Whelan A, Duffy J, Gaul RT, O'Reilly D, Nolan DR, Gunning P, Lally C, Murphy BP.

J Mech Behav Biomed Mater. 2019 Feb;90:54-60. doi: 10.1016/j.jmbbm.2018.09.038. Epub 2018 Sep 26.


Tackling poorly selected, collected, and reported outcomes in obstetrics and gynecology research.

Duffy JMN, Ziebland S, von Dadelszen P, McManus RJ.

Am J Obstet Gynecol. 2019 Jan;220(1):71.e1-71.e4. doi: 10.1016/j.ajog.2018.09.023. Epub 2018 Sep 28.


Popular interest in vertebrates does not reflect extinction risk and is associated with bias in conservation investment.

Davies T, Cowley A, Bennie J, Leyshon C, Inger R, Carter H, Robinson B, Duffy J, Casalegno S, Lambert G, Gaston K.

PLoS One. 2018 Sep 26;13(9):e0203694. doi: 10.1371/journal.pone.0203694. eCollection 2018. Erratum in: PLoS One. 2019 Feb 6;14(2):e0212101.


Antimalarial Lead-Optimization Studies on a 2,6-Imidazopyridine Series within a Constrained Chemical Space To Circumvent Atypical Dose-Response Curves against Multidrug Resistant Parasite Strains.

Le Manach C, Paquet T, Wicht K, Nchinda AT, Brunschwig C, Njoroge M, Gibhard L, Taylor D, Lawrence N, Wittlin S, Eyermann CJ, Basarab GS, Duffy J, Fish PV, Street LJ, Chibale K.

J Med Chem. 2018 Oct 25;61(20):9371-9385. doi: 10.1021/acs.jmedchem.8b01333. Epub 2018 Oct 16.


Authors' reply re: Inadequate safety reporting in pre-eclampsia trials: a systematic evaluation.

Duffy JM, Pealing L, McManus RJ; International Collaboration to Harmonise Outcomes for Pre-eclampsia (iHOPE).

BJOG. 2019 Jan;126(1):129. doi: 10.1111/1471-0528.15450. Epub 2018 Sep 21. No abstract available.


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