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Short Keynote Paper: Single molecule detection of protein biomarkers to define the continuum from health to disease.

Duffy D.

IEEE J Biomed Health Inform. 2020 Feb 4. doi: 10.1109/JBHI.2020.2971553. [Epub ahead of print]


Excellent survival and outcomes with fixed-bearing medial UKA in young patients (≤ 60 years) at minimum 10-year follow-up.

Mannan A, Pilling RWD, Mason K, Stirling P, Duffy D, London N.

Knee Surg Sports Traumatol Arthrosc. 2020 Feb 3. doi: 10.1007/s00167-020-05870-4. [Epub ahead of print]


Internet-Delivered Cognitive Behavior Therapy as a Prequel to Face-To-Face Therapy for Depression and Anxiety: A Naturalistic Observation.

Duffy D, Enrique A, Connell S, Connolly C, Richards D.

Front Psychiatry. 2020 Jan 9;10:902. doi: 10.3389/fpsyt.2019.00902. eCollection 2019.


Inhibition of IFNα secretion in cells from patients with juvenile dermatomyositis under TBK1 inhibitor treatment revealed by single-molecular assay technology.

Gitiaux C, Bondet V, Bekaddour N, Nusbaum P, Hubas A, Melki I, Bodemer C, Quartier P, Desguerre I, Crow YJ, Herbeuval JP, Duffy D, Bader Meunier B, Rodero MP.

Rheumatology (Oxford). 2020 Jan 23. pii: kez687. doi: 10.1093/rheumatology/kez687. [Epub ahead of print] No abstract available.


Antibody-coated microbiota in nasopharynx of healthy individuals and IVIg-treated patients with hypogammaglobulinemia.

Goncalves P, Charbit B, Lenoir C; Milieu Interieur Consortium, Duffy D, Fischer A, Di Santo JP.

J Allergy Clin Immunol. 2020 Jan 16. pii: S0091-6749(20)30036-1. doi: 10.1016/j.jaci.2020.01.002. [Epub ahead of print] No abstract available.


Direct Detection of miR-122 in Hepatotoxicity Using Dynamic Chemical Labeling Overcomes Stability and isomiR Challenges.

López-Longarela B, Morrison EE, Tranter JD, Chahman-Vos L, Léonard JF, Gautier JC, Laurent S, Lartigau A, Boitier E, Sautier L, Carmona-Saez P, Martorell-Marugan J, Mellanby RJ, Pernagallo S, Ilyine H, Rissin DM, Duffy DC, Dear JW, Díaz-Mochón JJ.

Anal Chem. 2020 Feb 18;92(4):3388-3395. doi: 10.1021/acs.analchem.9b05449. Epub 2020 Jan 27.


How complementary feeding in infants affects allergies, chronic disease, and neurodevelopment.

Duffy DM.

JAAPA. 2020 Feb;33(2):14-18. doi: 10.1097/01.JAA.0000651712.87289.d0.


Genetics and Gene-Environment Interactions in Childhood and Adult Onset Asthma.

Morales E, Duffy D.

Front Pediatr. 2019 Dec 11;7:499. doi: 10.3389/fped.2019.00499. eCollection 2019. Review.


Neuromyelitis optica in patients with increased interferon alpha concentrations.

Williams J, McGlasson S, Irani S, Duffy D, Crow Y, Hunt D; Scottish NMOSD study group.

Lancet Neurol. 2020 Jan;19(1):31-33. doi: 10.1016/S1474-4422(19)30445-4. No abstract available.


Severe type I interferonopathy and unrestrained interferon signaling due to a homozygous germline mutation in STAT2.

Duncan CJA, Thompson BJ, Chen R, Rice GI, Gothe F, Young DF, Lovell SC, Shuttleworth VG, Brocklebank V, Corner B, Skelton AJ, Bondet V, Coxhead J, Duffy D, Fourrage C, Livingston JH, Pavaine J, Cheesman E, Bitetti S, Grainger A, Acres M, Innes BA, Mikulasova A, Sun R, Hussain R, Wright R, Wynn R, Zarhrate M, Zeef LAH, Wood K, Hughes SM, Harris CL, Engelhardt KR, Crow YJ, Randall RE, Kavanagh D, Hambleton S, Briggs TA.

Sci Immunol. 2019 Dec 13;4(42). pii: eaav7501. doi: 10.1126/sciimmunol.aav7501.


Hydroxyl-rich macromolecules enable the bio-inspired synthesis of single crystal nanocomposites.

Kim YY, Darkins R, Broad A, Kulak AN, Holden MA, Nahi O, Armes SP, Tang CC, Thompson RF, Marin F, Duffy DM, Meldrum FC.

Nat Commun. 2019 Dec 12;10(1):5682. doi: 10.1038/s41467-019-13422-9.


The interplay of sun damage and genetic risk in Australian multiple and single primary melanoma cases and controls.

McMeniman EK, Duffy DL, Jagirdar K, Lee KJ, Peach E, McInerney-Leo AM, De'Ambrosis B, Rayner JE, Smithers BM, Soyer HP, Sturm RA.

Br J Dermatol. 2019 Dec 3. doi: 10.1111/bjd.18777. [Epub ahead of print]


Thrombospondin 1 (THBS1) Promotes Follicular Angiogenesis, Luteinization, and Ovulation in Primates.

Bender HR, Campbell GE, Aytoda P, Mathiesen AH, Duffy DM.

Front Endocrinol (Lausanne). 2019 Nov 7;10:727. doi: 10.3389/fendo.2019.00727. eCollection 2019.


PSMB10, the last immunoproteasome gene missing for PRAAS.

Sarrabay G, Méchin D, Salhi A, Boursier G, Rittore C, Crow Y, Rice G, Tran TA, Cezar R, Duffy D, Bondet V, Boudhane L, Broca C, Kant BP, VanGijn M, Grandemange S, Richard E, Apparailly F, Touitou I.

J Allergy Clin Immunol. 2019 Nov 26. pii: S0091-6749(19)31607-0. doi: 10.1016/j.jaci.2019.11.024. [Epub ahead of print] No abstract available.


Cardiac valve involvement in ADAR-related type I interferonopathy.

Crow Y, Keshavan N, Barbet JP, Bercu G, Bondet V, Boussard C, Dedieu N, Duffy D, Hully M, Giardini A, Gitiaux C, Rice GI, Seabra L, Bader-Meunier B, Rahman S.

J Med Genet. 2019 Nov 26. pii: jmedgenet-2019-106457. doi: 10.1136/jmedgenet-2019-106457. [Epub ahead of print]


Anti-MDA5 juvenile idiopathic inflammatory myopathy: a specific subgroup defined by differentially enhanced interferon-α signalling.

Melki I, Devilliers H, Gitiaux C, Bondet V, Duffy D, Charuel JL, Miyara M, Bokov P, Kheniche A, Kwon T, Authier FJ, Allenbach Y, Belot A, Bodemer C, Bourrat E, Dumaine C, Fabien N, Faye A, Frémond ML, Hadchouel A, Kitabayashi N, Lepelley A, Martin-Niclos MJ, Mudumba S, Musset L, Quartier P, Rice GI, Seabra L, Uettwiller F, Uggenti C, Viel S, Rodero MP, Crow YJ, Bader-Meunier B.

Rheumatology (Oxford). 2019 Nov 22. pii: kez525. doi: 10.1093/rheumatology/kez525. [Epub ahead of print]


Ex vivo comparison of the effect of storage temperature on canine intestinal leakage pressures.

Duffy DJ, Chang YJ, Balko JA, Moore GE.

Vet Surg. 2019 Nov 13. doi: 10.1111/vsu.13339. [Epub ahead of print]


Naevus count and MC1R R alleles contribute to melanoma risk.

Duffy DL, Lee KJ, Jagirdar K, Pflugfelder A, Stark MS, McMeniman EK, Soyer HP, Sturm RA.

Br J Dermatol. 2019 Nov;181(5):e119-e142. doi: 10.1111/bjd.18487.


Standalone DBT Group Skills Training Versus Standard (i.e. All Modes) DBT for Borderline Personality Disorder: A Natural Quasi-experiment in Routine Clinical Practice.

Lyng J, Swales MA, Hastings RP, Millar T, Duffy DJ, Booth R.

Community Ment Health J. 2020 Feb;56(2):238-250. doi: 10.1007/s10597-019-00485-7. Epub 2019 Oct 31.


Use of ruxolitinib in COPA syndrome manifesting as life-threatening alveolar haemorrhage.

Frémond ML, Legendre M, Fayon M, Clement A, Filhol-Blin E, Richard N, Berdah L, Roullaud S, Rice GI, Bondet V, Duffy D, Sileo C, Ducou le Pointe H, Begueret H, Coulomb A, Neven B, Amselem S, Crow Y, Nathan N.

Thorax. 2020 Jan;75(1):92-95. doi: 10.1136/thoraxjnl-2019-213892. Epub 2019 Oct 30.


Inhibition of IFNα secretion in cells from patients with juvenile dermatomyositis under TBK1 inhibitor treatment revealed by single-molecular assay technology.

Gitiaux C, Bondet V, Bekaddour N, Nusbaum P, Hubas A, Melki I, Bodemer C, Quartier P, Desguerre I, Crow YJ, Herbeuval JP, Duffy D, Bader Meunier B, Rodero MP.

Rheumatology (Oxford). 2019 Oct 30. pii: kez508. doi: 10.1093/rheumatology/kez508. [Epub ahead of print] No abstract available.


PAEA End of Rotation™ Exams Accurately Identify Students at Risk of Physician Assistant National Certifying Exam Failure.

Buchs SR, Baginski R, Coombs JM, Duffy D, Garbas B, Honda T, Moloney-Johns A, Mazur Z, Murfin M, Statler M, Thurnes T.

J Physician Assist Educ. 2019 Dec;30(4):192-199. doi: 10.1097/JPA.0000000000000274.


Effect of bite depth of an epitendinous suture on the biomechanical strength of repaired canine flexor tendons.

Duffy DJ, Chang YJ, Gaffney LS, Fisher MB, Moore GE.

Am J Vet Res. 2019 Nov;80(11):1043-1049. doi: 10.2460/ajvr.80.11.1043.


Effect of bite distance of an epitendinous suture from the repair site on the tensile strength of canine tendon constructs.

Duffy DJ, Cocca CJ, Kersh ME, Kim W, Moore GE.

Am J Vet Res. 2019 Nov;80(11):1034-1042. doi: 10.2460/ajvr.80.11.1034.


Variation at DENND1B and Asthma on the Island of Tristan da Cunha.

Duffy DL, Siminovitch KA, Zamel R, Chapman KR, Martin NG, Zamel N.

Twin Res Hum Genet. 2019 Oct;22(5):277-282. doi: 10.1017/thg.2019.82. Epub 2019 Oct 14.


Risk factors associated with myasthenia gravis in thymoma patients: The potential role of thymic germinal centers.

Lefeuvre CM, Payet CA, Fayet OM, Maillard S, Truffault F, Bondet V, Duffy D, de Montpreville V, Ghigna MR, Fadel E, Mansuet-Lupo A, Alifano M, Validire P, Gossot D, Behin A, Eymard B, Berrih-Aknin S, Le Panse R.

J Autoimmun. 2020 Jan;106:102337. doi: 10.1016/j.jaut.2019.102337. Epub 2019 Oct 5.


Complications and outcomes associated with unilateral thyroidectomy in dogs with naturally occurring thyroid tumors: 156 cases (2003-2015).

Reagan JK, Selmic LE, Fallon C, Sutton B, Lafferty M, Ben-Aderet D, Culp WTN, Liptak JM, Duffy D, Simons M, Boston S, Lana S.

J Am Vet Med Assoc. 2019 Oct 15;255(8):926-932. doi: 10.2460/javma.255.8.926.


A comprehensive assessment of demographic, environmental, and host genetic associations with gut microbiome diversity in healthy individuals.

Scepanovic P, Hodel F, Mondot S, Partula V, Byrd A, Hammer C, Alanio C, Bergstedt J, Patin E, Touvier M, Lantz O, Albert ML, Duffy D, Quintana-Murci L, Fellay J; Milieu Intérieur Consortium.

Microbiome. 2019 Sep 13;7(1):130. doi: 10.1186/s40168-019-0747-x.


Plasma Type I IFN Protein Concentrations in Human Tuberculosis.

Llibre A, Bilek N, Bondet V, Darboe F, Mbandi SK, Penn-Nicholson A, Hatherill M, Rozenberg F, Scriba TJ, Duffy D.

Front Cell Infect Microbiol. 2019 Aug 22;9:296. doi: 10.3389/fcimb.2019.00296. eCollection 2019.


Circulating Interferon-α Measured With a Highly Sensitive Assay as a Biomarker for Juvenile Inflammatory Myositis Activity: Comment on the Article by Mathian et al.

Melki I, Devilliers H, Gitiaux C, Bondet V, Belot A, Bodemer C, Quartier P, Crow YJ, Duffy D, Rodero MP, Bader Meunier B.

Arthritis Rheumatol. 2020 Jan;72(1):195-197. doi: 10.1002/art.41096. Epub 2019 Nov 23. No abstract available.


Genes Determining Nevus Count and Dermoscopic Appearance in Australian Melanoma Cases and Controls.

Duffy DL, Jagirdar K, Lee KJ, McWhirter SR, McMeniman EK, De'Ambrosis B, Pflugfelder A, Rayner JE, Whiteman DC, Brown MA, Martin NG, Smithers BM, Schaider H, Soyer HP, Sturm RA.

J Invest Dermatol. 2020 Feb;140(2):498-501.e17. doi: 10.1016/j.jid.2019.05.032. Epub 2019 Aug 15. No abstract available.


Historical trends in Hawaiian game harvest and hunter participation in Hawai'i from 1946-2008.

Lepczyk CA, Duffy DJ.

PLoS One. 2019 Aug 16;14(8):e0219283. doi: 10.1371/journal.pone.0219283. eCollection 2019.


Sensitivity and binding kinetics of an ultra-sensitive chemiluminescent enzyme-linked immunosorbent assay at arrays of antibodies.

Tobos CI, Kim S, Rissin DM, Johnson JM, Douglas S, Yan S, Nie S, Rice B, Sung KJ, Sikes HD, Duffy DC.

J Immunol Methods. 2019 Nov;474:112643. doi: 10.1016/j.jim.2019.112643. Epub 2019 Aug 8.


Toxin A-predominant Pathogenic C. difficile: A Novel Clinical Phenotype.

Lin Q, Pollock NR, Banz A, Lantz A, Xu H, Gu L, Gerding DN, Garey KW, Gonzales-Luna AJ, Zhao M, Song L, Duffy DC, Kelly CP, Chen X.

Clin Infect Dis. 2019 Aug 11. pii: ciz727. doi: 10.1093/cid/ciz727. [Epub ahead of print]


Clinical findings, diagnostic test results, and treatment outcome in cats with hiatal hernia: 31 cases (1995-2018).

Phillips H, Corrie J, Engel DM, Duffy DJ, Holt DE, Kendall AR, Schmiedt CW, Vetter A, Meren IL, Follette C, Schaeffer DJ, Mayhew PD, Marks SL.

J Vet Intern Med. 2019 Sep;33(5):1970-1976. doi: 10.1111/jvim.15583. Epub 2019 Aug 9.


Control of TLR7-mediated type I IFN signaling in pDCs through CXCR4 engagement-A new target for lupus treatment.

Smith N, Rodero MP, Bekaddour N, Bondet V, Ruiz-Blanco YB, Harms M, Mayer B, Bader-Meunier B, Quartier P, Bodemer C, Baudouin V, Dieudonné Y, Kirchhoff F, Sanchez Garcia E, Charbit B, Leboulanger N, Jahrsdörfer B, Richard Y, Korganow AS, Münch J, Nisole S, Duffy D, Herbeuval JP.

Sci Adv. 2019 Jul 10;5(7):eaav9019. doi: 10.1126/sciadv.aav9019. eCollection 2019 Jul.


Beyond the abacus: Leveraging the electronic medical record for central line day surveillance.

Burke PC, Eichmuller L, Messam M, Duffy DA, Borkowski RG, Gordon SM, Fraser TG.

Am J Infect Control. 2019 Nov;47(11):1397-1399. doi: 10.1016/j.ajic.2019.05.013. Epub 2019 Jul 2.


IRF4 rs12203592*T/T genotype is associated with nodular melanoma.

Rayner JE, McMeniman EK, Duffy DL, De'Ambrosis B, Smithers BM, Jagirdar K, Lee KJ, Soyer HP, Sturm RA.

Melanoma Res. 2019 Aug;29(4):445-446. doi: 10.1097/CMR.0000000000000596. No abstract available.


Effect of a continuous epitendinous suture as adjunct to three-loop pulley and locking-loop patterns for flexor tendon repair in a canine model.

Putterman AB, Duffy DJ, Kersh ME, Rahman H, Moore GE.

Vet Surg. 2019 Oct;48(7):1229-1236. doi: 10.1111/vsu.13268. Epub 2019 Jun 21.


Biomechanical comparison of three epitendinous suture patterns as adjuncts to a core locking loop suture for repair of canine flexor tendon injuries.

Cocca CJ, Duffy DJ, Kersh ME, Kim W, Groenewold A, Moore GE.

Vet Surg. 2019 Oct;48(7):1245-1252. doi: 10.1111/vsu.13266. Epub 2019 Jun 20.


Scientific Business Abstracts of the 112th Annual Meeting of the Association of Physicians of Great Britain and Ireland.

Chauhan A, Lalor T, Watson S, Adams D, Farrah TE, Anand A, Kimmitt R, Mills NL, Webb DJ, Dhaun N, Kalla R, Adams A, Vatn S, Bonfliglio F, Nimmo E, Kennedy N, Ventham N, Vatn M, Ricanek P, Halfvarson J, Soderhollm J, Pierik M, Torkvist L, Gomollon F, Gut I, Jahnsen J, Satsangi J, Body R, Almashali M, McDowell G, Taylor P, Lacey A, Rees A, Dayan C, Lazarus J, Nelson S, Okosieme O, Corcoran D, Young R, Ciadella P, McCartney P, Bajrangee A, Hennigan B, Collison D, Carrick D, Shaukat A, Good R, Watkins S, McEntegart M, Watt J, Welsh P, Sattar N, McConnachie A, Oldroyd K, Berry C, Parks T, Auckland K, Mentzer AJ, Kado J, Mirabel MM, Kauwe JK, Robson KJ, Mittal B, Steer AC, Hill AVS, Akbar M, Forrester M, Virlan AT, Gilmour A, Wallace C, Paterson C, Reid D, Siebert S, Porter D, Liversidge J, McInnes I, Goodyear C, Athwal V, Pritchett J, Zaitoun A, Irving W, Guha IN, Hanley NA, Hanley KP, Briggs T, Reynolds J, Rice G, Bondet V, Bruce E, Crow Y, Duffy D, Parker B, Bruce I, Martin K, Pritchett J, Aoibheann Mullan M, Llewellyn J, Athwal V, Zeef L, Farrow S, Streuli C, Henderson N, Friedman S, Hanley N, Hanley KP.

QJM. 2018 Dec 1;111(12):920-924. doi: 10.1093/qjmed/hcy193. No abstract available.


A Call for Blood-In Human Immunology.

Brodin P, Duffy D, Quintana-Murci L.

Immunity. 2019 Jun 18;50(6):1335-1336. doi: 10.1016/j.immuni.2019.05.012. No abstract available.


Type I interferon in patients with systemic autoimmune rheumatic disease is associated with haematological abnormalities and specific autoantibody profiles.

Reynolds JA, Briggs TA, Rice GI, Darmalinggam S, Bondet V, Bruce E, Khan M, Haque S, Chinoy H, Herrick AL, McCarthy EM, Zeef L, Hayes A, Duffy D, Parker B, Bruce IN.

Arthritis Res Ther. 2019 Jun 14;21(1):147. doi: 10.1186/s13075-019-1929-4.


Pathology in Practice.

Schlein LJ, Connolly SL, Moran C, Duffy DJ.

J Am Vet Med Assoc. 2019 Jul 1;255(1):67-70. doi: 10.2460/javma.255.1.67. No abstract available.


Publisher Correction: Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability.

Hysi PG, Valdes AM, Liu F, Furlotte NA, Evans DM, Bataille V, Visconti A, Hemani G, McMahon G, Ring SM, Smith GD, Duffy DL, Zhu G, Gordon SD, Medland SE, Lin BD, Willemsen G, Jan Hottenga J, Vuckovic D, Girotto G, Gandin I, Sala C, Concas MP, Brumat M, Gasparini P, Toniolo D, Cocca M, Robino A, Yazar S, Hewitt AW, Chen Y, Zeng C, Uitterlinden AG, Ikram MA, Hamer MA, van Duijn CM, Nijsten T, Mackey DA, Falchi M, Boomsma DI, Martin NG; International Visible Trait Genetics Consortium, Hinds DA, Kayser M, Spector TD.

Nat Genet. 2019 Jul;51(7):1190. doi: 10.1038/s41588-019-0446-3.


Analysis of outcomes following treatment of craniodorsal hip luxation with closed reduction and Ehmer sling application in dogs.

Schlag AN, Hayes GM, Taylor AQ, Kerwin SC, Dugat DR, Vitt MA, Stratton DT, Duffy DJ.

J Am Vet Med Assoc. 2019 Jun 15;254(12):1436-1440. doi: 10.2460/javma.254.12.1436.


IP-10 contributes to the inhibition of mycobacterial growth in an ex vivo whole blood assay.

Palucci I, Battah B, Salustri A, De Maio F, Petrone L, Ciccosanti F, Sali M, Bondet V, Duffy D, Fimia GM, Goletti D, Delogu G.

Int J Med Microbiol. 2019 Jul;309(5):299-306. doi: 10.1016/j.ijmm.2019.05.005. Epub 2019 May 22.


Sex differences in IL-17 contribute to chronicity in male versus female urinary tract infection.

Zychlinsky Scharff A, Rousseau M, Lacerda Mariano L, Canton T, Consiglio CR, Albert ML, Fontes M, Duffy D, Ingersoll MA.

JCI Insight. 2019 May 30;5. pii: 122998. doi: 10.1172/jci.insight.122998.


Oxygen therapy in premature low birth weight infants is associated with capillary loss and increases in blood pressure: a pilot study.

Raghuraman RP, Duffy D, Carroll VA, Manyonda I, Antonios TF.

J Hum Hypertens. 2019 May 9. doi: 10.1038/s41371-019-0211-1. [Epub ahead of print]


Associations between usual diet and gut microbiota composition: results from the Milieu Intérieur cross-sectional study.

Partula V, Mondot S, Torres MJ, Kesse-Guyot E, Deschasaux M, Assmann K, Latino-Martel P, Buscail C, Julia C, Galan P, Hercberg S, Rouilly V, Thomas S, Quintana-Murci L, Albert ML, Duffy D, Lantz O, Touvier M; Milieu Intérieur Consortium.

Am J Clin Nutr. 2019 May 1;109(5):1472-1483. doi: 10.1093/ajcn/nqz029.


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