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Standardized Immunomonitoring: Separating the Signals from the Noise.

Duffy D.

Trends Biotechnol. 2018 Nov;36(11):1107-1115. doi: 10.1016/j.tibtech.2018.06.002. Epub 2018 Jun 29. Review.


A child with severe juvenile dermatomyositis treated with ruxolitinib.

Aeschlimann FA, Frémond ML, Duffy D, Rice GI, Charuel JL, Bondet V, Saire E, Neven B, Bodemer C, Balu L, Gitiaux C, Crow YJ, Bader-Meunier B.

Brain. 2018 Nov 1;141(11):e80. doi: 10.1093/brain/awy255. No abstract available.


Cell-type-specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes.

Zhang T, Choi J, Kovacs MA, Shi J, Xu M; NISC Comparative Sequencing Program; Melanoma Meta-Analysis Consortium, Goldstein AM, Trower AJ, Bishop DT, Iles MM, Duffy DL, MacGregor S, Amundadottir LT, Law MH, Loftus SK, Pavan WJ, Brown KM.

Genome Res. 2018 Nov;28(11):1621-1635. doi: 10.1101/gr.233304.117. Epub 2018 Oct 17.


Immune response biomarkers in human and veterinary research.

Llibre A, Duffy D.

Comp Immunol Microbiol Infect Dis. 2018 Aug;59:57-62. doi: 10.1016/j.cimid.2018.09.008. Epub 2018 Sep 24.


Efficacy of JAK1/2 inhibition in the treatment of chilblain lupus due to TREX1 deficiency.

Briand C, Frémond ML, Bessis D, Carbasse A, Rice GI, Bondet V, Duffy D, Chatenoud L, Blanche S, Crow YJ, Neven B.

Ann Rheum Dis. 2018 Oct 3. pii: annrheumdis-2018-214037. doi: 10.1136/annrheumdis-2018-214037. [Epub ahead of print] No abstract available.


Supported Internet-Delivered Cognitive Behavior Treatment for Adults with Severe Depressive Symptoms: A Secondary Analysis.

Richards D, Duffy D, Burke J, Anderson M, Connell S, Timulak L.

JMIR Ment Health. 2018 Oct 2;5(4):e10204. doi: 10.2196/10204.


Sea turtle fibropapilloma tumors share genomic drivers and therapeutic vulnerabilities with human cancers.

Duffy DJ, Schnitzler C, Karpinski L, Thomas R, Whilde J, Eastman C, Yang C, Krstic A, Rollinson D, Zirkelbach B, Yetsko K, Burkhalter B, Martindale MQ.

Commun Biol. 2018 Jun 7;1:63. doi: 10.1038/s42003-018-0059-x. eCollection 2018.


Effect of implementation of a surgical safety checklist on perioperative and postoperative complications at an academic institution in North America.

Cray MT, Selmic LE, McConnell BM, Lamoureux LM, Duffy DJ, Harper TA, Philips H, Hague DW, Foss KD.

Vet Surg. 2018 Nov;47(8):1052-1065. doi: 10.1111/vsu.12964. Epub 2018 Sep 24.


Potential utility of the Genedrive point-of-care test for HCV RNA detection.

Llibre A, Shimakawa Y, Duffy D.

Gut. 2018 Sep 22. pii: gutjnl-2018-317218. doi: 10.1136/gutjnl-2018-317218. [Epub ahead of print] No abstract available.


Pharmacokinetics and Safety of CSL112 (Apolipoprotein A-I [Human]) in Adults With Moderate Renal Impairment and Normal Renal Function.

Tortorici MA, Duffy D, Evans R, Feaster J, Gille A, Mant TGK, Wright SD, D'Andrea D.

Clin Pharmacol Drug Dev. 2018 Sep 21. doi: 10.1002/cpdd.618. [Epub ahead of print]


'Mind your Moles' study: protocol of a prospective cohort study of melanocytic naevi.

Koh U, Janda M, Aitken JF, Duffy DL, Menzies S, Sturm RA, Schaider H, Betz-Stablein B, Prow T, Soyer HP, Green AC.

BMJ Open. 2018 Sep 19;8(9):e025857. doi: 10.1136/bmjopen-2018-025857.


First description of agonist and antagonist IP-10 in urine of patients with active TB.

Petrone L, Bondet V, Vanini V, Cuzzi G, Palmieri F, Palucci I, Delogu G, Ciccosanti F, Fimia GM, Blauenfeldt T, Ruhwald M, Duffy D, Goletti D.

Int J Infect Dis. 2018 Sep 7. pii: S1201-9712(18)34513-2. doi: 10.1016/j.ijid.2018.09.001. [Epub ahead of print]


Human thymopoiesis is influenced by a common genetic variant within the TCRA-TCRD locus.

Clave E, Araujo IL, Alanio C, Patin E, Bergstedt J, Urrutia A, Lopez-Lastra S, Li Y, Charbit B, MacPherson CR, Hasan M, Melo-Lima BL, Douay C, Saut N, Germain M, Trégouët DA, Morange PE, Fontes M, Duffy D, Di Santo JP, Quintana-Murci L, Albert ML, Toubert A; Milieu Intérieur Consortium.

Sci Transl Med. 2018 Sep 5;10(457). pii: eaao2966. doi: 10.1126/scitranslmed.aao2966.


A formative evaluation of online information to support abortion access in England, Northern Ireland and the Republic of Ireland.

Duffy DN, Pierson C, Best P.

BMJ Sex Reprod Health. 2018 Sep 4. pii: bmjsrh-2018-200086. doi: 10.1136/bmjsrh-2018-200086. [Epub ahead of print]


Influence of barbed suture on leak pressures after double-layer inverting closure of cystotomy sites in sheep.

Duffy DJ, Duddy HR, Keating S, Gutierrez-Nibeyro SD.

Vet Surg. 2018 Oct;47(7):902-907. doi: 10.1111/vsu.12935. Epub 2018 Sep 4.


Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines.

Scepanovic P, Alanio C, Hammer C, Hodel F, Bergstedt J, Patin E, Thorball CW, Chaturvedi N, Charbit B, Abel L, Quintana-Murci L, Duffy D, Albert ML, Fellay J; Milieu Intérieur Consortium.

Genome Med. 2018 Jul 27;10(1):59. doi: 10.1186/s13073-018-0568-8.


Mitochondrial double-stranded RNA triggers antiviral signalling in humans.

Dhir A, Dhir S, Borowski LS, Jimenez L, Teitell M, Rötig A, Crow YJ, Rice GI, Duffy D, Tamby C, Nojima T, Munnich A, Schiff M, de Almeida CR, Rehwinkel J, Dziembowski A, Szczesny RJ, Proudfoot NJ.

Nature. 2018 Aug;560(7717):238-242. doi: 10.1038/s41586-018-0363-0. Epub 2018 Jul 25.


Interplay of DDP4 and IP-10 as a Potential Mechanism for Cell Recruitment to Tuberculosis Lesions.

Blauenfeldt T, Petrone L, Del Nonno F, Baiocchini A, Falasca L, Chiacchio T, Bondet V, Vanini V, Palmieri F, Galluccio G, Casrouge A, Eugen-Olsen J, Albert ML, Goletti D, Duffy D, Ruhwald M.

Front Immunol. 2018 Jul 5;9:1456. doi: 10.3389/fimmu.2018.01456. eCollection 2018.


Identifying the etiology and pathophysiology underlying stunting and environmental enteropathy: study protocol of the AFRIBIOTA project.

Vonaesch P, Randremanana R, Gody JC, Collard JM, Giles-Vernick T, Doria M, Vigan-Womas I, Rubbo PA, Etienne A, Andriatahirintsoa EJ, Kapel N, Brown E, Huus KE, Duffy D, Finlay BB, Hasan M, Hunald FA, Robinson A, Manirakiza A, Wegener-Parfrey L, Vray M, Sansonetti PJ; AFRIBIOTA Investigators.

BMC Pediatr. 2018 Jul 19;18(1):236. doi: 10.1186/s12887-018-1189-5.


Systemic DPP4 activity is reduced during primary HIV-1 infection and is associated with intestinal RORC+ CD4+ cell levels: a surrogate marker candidate of HIV-induced intestinal damage.

Ploquin MJ, Casrouge A, Madec Y, Noël N, Jacquelin B, Huot N, Duffy D, Jochems SP, Micci L, Lécuroux C, Boufassa F, Booiman T, Garcia-Tellez T, Ghislain M, Grand RL, Lambotte O, Kootstra N, Meyer L, Goujard C, Paiardini M, Albert ML, Müller-Trutwin M.

J Int AIDS Soc. 2018 Jul;21(7):e25144. doi: 10.1002/jia2.25144.


Development and Validation of an Ultrasensitive Single Molecule Array Digital Enzyme-linked Immunosorbent Assay for Human Interferon-α.

Llibre A, Bondet V, Rodero MP, Hunt D, Crow YJ, Duffy D.

J Vis Exp. 2018 Jun 14;(136). doi: 10.3791/57421.


Plasmacytoid dendritic cells control dengue and Chikungunya virus infections via IRF7-regulated interferon responses.

Webster B, Werneke SW, Zafirova B, This S, Coléon S, Décembre E, Paidassi H, Bouvier I, Joubert PE, Duffy D, Walzer T, Albert ML, Dreux M.

Elife. 2018 Jun 19;7. pii: e34273. doi: 10.7554/eLife.34273.


Using population viability analysis to evaluate management activities for an endangered Hawaiian endemic, the Puaiohi (Myadestes palmeri).

Fantle-Lepczyk J, Taylor A, Duffy DC, Crampton LH, Conant S.

PLoS One. 2018 Jun 13;13(6):e0198952. doi: 10.1371/journal.pone.0198952. eCollection 2018.


The Relationship Between Personality and Somatic and Psychological Distress: A Comparison of Chinese and Australian Adolescents.

Liu Y, Gillespie NA, Ye L, Zhu G, Duffy DL, Martin NG.

Behav Genet. 2018 Jun 5. doi: 10.1007/s10519-018-9905-3. [Epub ahead of print]


Accuracy of Inferred APOE Genotypes for a Range of Genotyping Arrays and Imputation Reference Panels.

Lupton MK, Medland SE, Gordon SD, Goncalves T, MacGregor S, Mackey DA, Young TL, Duffy DL, Visscher PM, Wray NR, Nyholt DR, Bain L, Ferreira MA, Henders AK, Wallace L, Montgomery GW, Wright MJ, Martin NG.

J Alzheimers Dis. 2018;64(1):49-54. doi: 10.3233/JAD-171104.


Comment on: 'Aberrant tRNA processing causes an autoinflammatory syndrome responsive to TNF inhibitors' by Giannelou et al: mutations in TRNT1 result in a constitutive activation of type I interferon signalling.

Frémond ML, Melki I, Kracker S, Bondet V, Duffy D, Rice GI, Crow YJ, Bader-Meunier B.

Ann Rheum Dis. 2018 Jun 1. pii: annrheumdis-2018-213745. doi: 10.1136/annrheumdis-2018-213745. [Epub ahead of print] No abstract available.


Study of the Humoral Immune Response towards HCV Genotype 4 Using a Bead-Based Multiplex Serological Assay.

Filomena A, Göpfert JC, Duffy D, Pol S, Abdel-Hamid M, Esmat G, Fontanet A, Albert ML, Joos TO, Schneiderhan-Marra N.

High Throughput. 2017 Oct 30;6(4). pii: E15. doi: 10.3390/ht6040015.


Development of a Bead-Based Multiplex Assay for the Analysis of the Serological Response against the Six Pathogens HAV, HBV, HCV, CMV, T. gondii, and H. pylori.

Filomena A, Pessler F, Akmatov MK, Krause G, Duffy D, Gärtner B, Gerhard M, Albert ML, Joos TO, Schneiderhan-Marra N.

High Throughput. 2017 Oct 30;6(4). pii: E14. doi: 10.3390/ht6040014.


Amino Acid Assisted Incorporation of Dye Molecules within Calcite Crystals.

Marzec B, Green DC, Holden MA, Coté AS, Ihli J, Khalid S, Kulak A, Walker D, Tang C, Duffy DM, Kim YY, Meldrum FC.

Angew Chem Int Ed Engl. 2018 Jul 9;57(28):8623-8628. doi: 10.1002/anie.201804365. Epub 2018 Jun 10.


Cosmetic Dermatology Training During Residency: Outcomes of a Resident-Reported Survey.

Champlain A, Reserva J, Webb K, Griffin D, Moy L, Joyce C, Glaser DA, Lawrence N, Lee KC, Antonovich DD, Duffy DM, Kim J, Ozog D, Sobanko J, Alam M, Tung RC.

Dermatol Surg. 2018 Sep;44(9):1216-1219. doi: 10.1097/DSS.0000000000001557.


JAK inhibitor improves type I interferon induced damage: proof of concept in dermatomyositis.

Ladislau L, Suárez-Calvet X, Toquet S, Landon-Cardinal O, Amelin D, Depp M, Rodero MP, Hathazi D, Duffy D, Bondet V, Preusse C, Bienvenu B, Rozenberg F, Roos A, Benjamim CF, Gallardo E, Illa I, Mouly V, Stenzel W, Butler-Browne G, Benveniste O, Allenbach Y.

Brain. 2018 Jun 1;141(6):1609-1621. doi: 10.1093/brain/awy105.


Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure.

Visconti A, Duffy DL, Liu F, Zhu G, Wu W, Chen Y, Hysi PG, Zeng C, Sanna M, Iles MM, Kanetsky PA, Demenais F, Hamer MA, Uitterlinden AG, Ikram MA, Nijsten T, Martin NG, Kayser M, Spector TD, Han J, Bataille V, Falchi M.

Nat Commun. 2018 May 8;9(1):1684. doi: 10.1038/s41467-018-04086-y.


Publisher Correction: Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors.

Patin E, Hasan M, Bergstedt J, Rouilly V, Libri V, Urrutia A, Alanio C, Scepanovic P, Hammer C, Jönsson F, Beitz B, Quach H, Lim YW, Hunkapiller J, Zepeda M, Green C, Piasecka B, Leloup C, Rogge L, Huetz F, Peguillet I, Lantz O, Fontes M, Di Santo JP, Thomas S, Fellay J, Duffy D, Quintana-Murci L, Albert ML; Milieu Intérieur Consortium.

Nat Immunol. 2018 Jun;19(6):645. doi: 10.1038/s41590-018-0105-3.


Milieu intérieur: Defining the boundaries of a healthy immune response for improved vaccination strategies.

Duffy D.

Hum Vaccin Immunother. 2018;14(9):2217-2221. doi: 10.1080/21645515.2018.1466764. Epub 2018 Jul 24.


Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability.

Hysi PG, Valdes AM, Liu F, Furlotte NA, Evans DM, Bataille V, Visconti A, Hemani G, McMahon G, Ring SM, Smith GD, Duffy DL, Zhu G, Gordon SD, Medland SE, Lin BD, Willemsen G, Jan Hottenga J, Vuckovic D, Girotto G, Gandin I, Sala C, Concas MP, Brumat M, Gasparini P, Toniolo D, Cocca M, Robino A, Yazar S, Hewitt AW, Chen Y, Zeng C, Uitterlinden AG, Ikram MA, Hamer MA, van Duijn CM, Nijsten T, Mackey DA, Falchi M, Boomsma DI, Martin NG, Hinds DA, Kayser M, Spector TD; International Visible Trait Genetics Consortium; International Visible Trait Genetics Consortium.

Nat Genet. 2018 May;50(5):652-656. doi: 10.1038/s41588-018-0100-5. Epub 2018 Apr 16.


Ovulatory Induction of SCG2 in Human, Nonhuman Primate, and Rodent Granulosa Cells Stimulates Ovarian Angiogenesis.

Hannon PR, Duffy DM, Rosewell KL, Brännström M, Akin JW, Curry TE Jr.

Endocrinology. 2018 Jun 1;159(6):2447-2458. doi: 10.1210/en.2018-00020.


Development and clinical validation of the Genedrive point-of-care test for qualitative detection of hepatitis C virus.

Llibre A, Shimakawa Y, Mottez E, Ainsworth S, Buivan TP, Firth R, Harrison E, Rosenberg AR, Meritet JF, Fontanet A, Castan P, Madejón A, Laverick M, Glass A, Viana R, Pol S, McClure CP, Irving WL, Miele G, Albert ML, Duffy D.

Gut. 2018 Nov;67(11):2017-2024. doi: 10.1136/gutjnl-2017-315783. Epub 2018 Apr 3.


Regarding global pediatric surgery training opportunities.

Baird R, Pandya K, Lal DR, Calkins CM, Oldham KT, Tsai A, Naik-Mathuria B, St-Louis E, Luc MK, LaRusso K, Petroze R, Lofberg KM, Biller CK, Villalona GA, Gourlay DM, Klein M, DeUgarte D, Cleary M, Berdan EA, Siddiqui S, Lo A, Langer M, Duffy D, Blair G, Beres A, Laberge JM, Berdan EA, Radulescu A, Holterman A, Hoover JD, Fitzgerald T, Ganey M, Krishnaswami S, Ozgediz D.

J Pediatr Surg. 2018 Jun;53(6):1256-1258. doi: 10.1016/j.jpedsurg.2018.03.003. Epub 2018 Mar 8. No abstract available.


T-cell biomarkers for diagnosis of tuberculosis: candidate evaluation by a simple whole blood assay for clinical translation.

Musvosvi M, Duffy D, Filander E, Africa H, Mabwe S, Jaxa L, Bilek N, Llibre A, Rouilly V, Hatherill M, Albert M, Scriba TJ, Nemes E.

Eur Respir J. 2018 Mar 22;51(3). pii: 1800153. doi: 10.1183/13993003.00153-2018. Print 2018 Mar. No abstract available.


Aggression toward Familiar People, Strangers, and Conspecifics in Gonadectomized and Intact Dogs.

Farhoody P, Mallawaarachchi I, Tarwater PM, Serpell JA, Duffy DL, Zink C.

Front Vet Sci. 2018 Feb 26;5:18. doi: 10.3389/fvets.2018.00018. eCollection 2018.


Digital IAPT: the effectiveness & cost-effectiveness of internet-delivered interventions for depression and anxiety disorders in the Improving Access to Psychological Therapies programme: study protocol for a randomised control trial.

Richards D, Duffy D, Blackburn B, Earley C, Enrique A, Palacios J, Franklin M, Clarke G, Sollesse S, Connell S, Timulak L.

BMC Psychiatry. 2018 Mar 2;18(1):59. doi: 10.1186/s12888-018-1639-5.


Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors.

Patin E, Hasan M, Bergstedt J, Rouilly V, Libri V, Urrutia A, Alanio C, Scepanovic P, Hammer C, Jönsson F, Beitz B, Quach H, Lim YW, Hunkapiller J, Zepeda M, Green C, Piasecka B, Leloup C, Rogge L, Huetz F, Peguillet I, Lantz O, Fontes M, Di Santo JP, Thomas S, Fellay J, Duffy D, Quintana-Murci L, Albert ML; Milieu Intérieur Consortium.

Nat Immunol. 2018 Mar;19(3):302-314. doi: 10.1038/s41590-018-0049-7. Epub 2018 Feb 23. Erratum in: Nat Immunol. 2018 May 3;:.


Towards the full spectrum of genes for human skin colour.

Sturm RA, Duffy DL.

Pigment Cell Melanoma Res. 2018 Jul;31(4):457-458. doi: 10.1111/pcmr.12691. Epub 2018 Feb 26. No abstract available.


Acquired melanocytic naevus phenotypes and MC1R genotypes in Han Chinese: a cross-sectional study.

Li X, Lee KJ, Duffy DL, Xu D, Basude MER, Hu Y, Zhang H, Jagirdar K, Soyer HP, Dong H, Sturm RA.

PeerJ. 2017 Dec 20;5:e4168. doi: 10.7717/peerj.4168. eCollection 2017.


Finding the perfect sclerosant - Is it possible?

Duffy DM.

Phlebology. 2018 Aug;33(7):502. doi: 10.1177/0268355517753448. Epub 2018 Jan 16. No abstract available.


Iris pigmented lesions as a marker of cutaneous melanoma risk: an Australian case-control study.

Laino AM, Berry EG, Jagirdar K, Lee KJ, Duffy DL, Soyer HP, Sturm RA.

Br J Dermatol. 2018 May;178(5):1119-1127. doi: 10.1111/bjd.16323. Epub 2018 Apr 6.


Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges.

Piasecka B, Duffy D, Urrutia A, Quach H, Patin E, Posseme C, Bergstedt J, Charbit B, Rouilly V, MacPherson CR, Hasan M, Albaud B, Gentien D, Fellay J, Albert ML, Quintana-Murci L; Milieu Intérieur Consortium.

Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):E488-E497. doi: 10.1073/pnas.1714765115. Epub 2017 Dec 27.


Type I interferon-mediated autoinflammation due to DNase II deficiency.

Rodero MP, Tesser A, Bartok E, Rice GI, Della Mina E, Depp M, Beitz B, Bondet V, Cagnard N, Duffy D, Dussiot M, Frémond ML, Gattorno M, Guillem F, Kitabayashi N, Porcheray F, Rieux-Laucat F, Seabra L, Uggenti C, Volpi S, Zeef LAH, Alyanakian MA, Beltrand J, Bianco AM, Boddaert N, Brouzes C, Candon S, Caorsi R, Charbit M, Fabre M, Faletra F, Girard M, Harroche A, Hartmann E, Lasne D, Marcuzzi A, Neven B, Nitschke P, Pascreau T, Pastore S, Picard C, Picco P, Piscianz E, Polak M, Quartier P, Rabant M, Stocco G, Taddio A, Uettwiller F, Valencic E, Vozzi D, Hartmann G, Barchet W, Hermine O, Bader-Meunier B, Tommasini A, Crow YJ.

Nat Commun. 2017 Dec 19;8(1):2176. doi: 10.1038/s41467-017-01932-3.


Improving the Functional Control of Aged Ferroelectrics Using Insights from Atomistic Modeling.

Chapman JBJ, Cohen RE, Kimmel AV, Duffy DM.

Phys Rev Lett. 2017 Oct 27;119(17):177602. doi: 10.1103/PhysRevLett.119.177602. Epub 2017 Oct 24.


Coherent nanoparticles in calcite.

Duffy DM.

Science. 2017 Dec 8;358(6368):1254-1255. doi: 10.1126/science.aaq0111. No abstract available.


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