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Items: 1 to 50 of 65

1.

A Large Panel of Isogenic APP and PSEN1 Mutant Human iPSC Neurons Reveals Shared Endosomal Abnormalities Mediated by APP β-CTFs, Not Aβ.

Kwart D, Gregg A, Scheckel C, Murphy E, Paquet D, Duffield M, Fak J, Olsen O, Darnell R, Tessier-Lavigne M.

Neuron. 2019 Aug 12. pii: S0896-6273(19)30636-1. doi: 10.1016/j.neuron.2019.07.010. [Epub ahead of print]

PMID:
31416668
2.

Eye-controlled, power wheelchair performs well for ALS patients.

Elliott MA, Malvar H, Maassel LL, Campbell J, Kulkarni H, Spiridonova I, Sophy N, Beavers J, Paradiso A, Needham C, Rifley J, Duffield M, Crawford J, Wood B, Cox EJ, Scanlan JM.

Muscle Nerve. 2019 Nov;60(5):513-519. doi: 10.1002/mus.26655. Epub 2019 Aug 21.

PMID:
31397910
3.

The effects of add-on corticosteroids on renal outcomes in patients with biopsy proven HIV associated nephropathy: a single centre study from South Africa.

Wearne N, Swanepoel CR, Duffield MS, Davidson BJ, Manning K, Tiffin N, Boulle A, Rayner BL, Naidu P, Okpechi IG.

BMC Nephrol. 2019 Feb 6;20(1):44. doi: 10.1186/s12882-019-1208-2.

4.

Huntingtin-associated protein-1 (HAP1) regulates endocytosis and interacts with multiple trafficking-related proteins.

Mackenzie KD, Lim Y, Duffield MD, Chataway T, Zhou XF, Keating DJ.

Cell Signal. 2017 Jul;35:176-187. doi: 10.1016/j.cellsig.2017.02.023. Epub 2017 Mar 1.

PMID:
28259758
5.

Huntingtin-associated protein-1 is a synapsin I-binding protein regulating synaptic vesicle exocytosis and synapsin I trafficking.

Mackenzie KD, Lumsden AL, Guo F, Duffield MD, Chataway T, Lim Y, Zhou XF, Keating DJ.

J Neurochem. 2016 Sep;138(5):710-21. doi: 10.1111/jnc.13703. Epub 2016 Jul 18.

6.

A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes.

Peiris H, Duffield MD, Fadista J, Jessup CF, Kashmir V, Genders AJ, McGee SL, Martin AM, Saiedi M, Morton N, Carter R, Cousin MA, Kokotos AC, Oskolkov N, Volkov P, Hough TA, Fisher EM, Tybulewicz VL, Busciglio J, Coskun PE, Becker A, Belichenko PV, Mobley WC, Ryan MT, Chan JY, Laybutt DR, Coates PT, Yang S, Ling C, Groop L, Pritchard MA, Keating DJ.

PLoS Genet. 2016 May 19;12(5):e1006033. doi: 10.1371/journal.pgen.1006033. eCollection 2016 May.

7.

The treatment of carcinoma in situ and squamous cell carcinoma of the conjunctiva with fractionated strontium-90 radiation in a population with a high prevalence of HIV.

Lecuona K, Stannard C, Hart G, Rice J, Cook C, Wetter J, Duffield M.

Br J Ophthalmol. 2015 Sep;99(9):1158-61. doi: 10.1136/bjophthalmol-2014-306327. Epub 2015 Mar 17.

PMID:
25784215
8.

Homozygous mutation of STXBP5L explains an autosomal recessive infantile-onset neurodegenerative disorder.

Kumar R, Corbett MA, Smith NJ, Jolly LA, Tan C, Keating DJ, Duffield MD, Utsumi T, Moriya K, Smith KR, Hoischen A, Abbott K, Harbord MG, Compton AG, Woenig JA, Arts P, Kwint M, Wieskamp N, Gijsen S, Veltman JA, Bahlo M, Gleeson JG, Haan E, Gecz J.

Hum Mol Genet. 2015 Apr 1;24(7):2000-10. doi: 10.1093/hmg/ddu614. Epub 2014 Dec 11.

PMID:
25504045
9.

Oxygen-dependent hydroxylation by FIH regulates the TRPV3 ion channel.

Karttunen S, Duffield M, Scrimgeour NR, Squires L, Lim WL, Dallas ML, Scragg JL, Chicher J, Dave KA, Whitelaw ML, Peers C, Gorman JJ, Gleadle JM, Rychkov GY, Peet DJ.

J Cell Sci. 2015 Jan 15;128(2):225-31. doi: 10.1242/jcs.158451. Epub 2014 Nov 20.

10.

Outcome of patients with primary immune-complex type mesangiocapillary glomerulonephritis (MCGN) in Cape Town South Africa.

Okpechi IG, Dlamini TA, Duffield M, Rayner BL, Moturi G, Swanepoel CR.

PLoS One. 2014 Nov 20;9(11):e113302. doi: 10.1371/journal.pone.0113302. eCollection 2014.

11.
12.

Huntingtin-associated protein 1 regulates exocytosis, vesicle docking, readily releasable pool size and fusion pore stability in mouse chromaffin cells.

Mackenzie KD, Duffield MD, Peiris H, Phillips L, Zanin MP, Teo EH, Zhou XF, Keating DJ.

J Physiol. 2014 Apr 1;592(7):1505-18. doi: 10.1113/jphysiol.2013.268342. Epub 2013 Dec 23.

13.

Identification of unique release kinetics of serotonin from guinea-pig and human enterochromaffin cells.

Raghupathi R, Duffield MD, Zelkas L, Meedeniya A, Brookes SJ, Sia TC, Wattchow DA, Spencer NJ, Keating DJ.

J Physiol. 2013 Dec 1;591(23):5959-75. doi: 10.1113/jphysiol.2013.259796. Epub 2013 Oct 7.

14.

Copper modulates the large dense core vesicle secretory pathway in PC12 cells.

Duncan C, Bica L, Crouch PJ, Caragounis A, Lidgerwood GE, Parker SJ, Meyerowitz J, Volitakis I, Liddell JR, Raghupathi R, Paterson BM, Duffield MD, Cappai R, Donnelly PS, Grubman A, Camakaris J, Keating DJ, White AR.

Metallomics. 2013 Jun;5(6):700-14. doi: 10.1039/c3mt20231c.

PMID:
23661118
15.

Structure and function of cytidine monophosphate kinase from Yersinia pseudotuberculosis, essential for virulence but not for survival.

Walker NJ, Clark EA, Ford DC, Bullifent HL, McAlister EV, Duffield ML, Acharya KR, Oyston PC.

Open Biol. 2012 Dec 5;2(12):120142. doi: 10.1098/rsob.120142.

16.

The evolution of our knowledge of HIV-associated kidney disease in Africa.

Swanepoel CR, Wearne N, Duffield MS, Okpechi IG.

Am J Kidney Dis. 2012 Oct;60(4):668-78. doi: 10.1053/j.ajkd.2012.04.034. Epub 2012 Aug 14.

PMID:
22901595
17.

Outcome of patients with membranous lupus nephritis in Cape Town South Africa.

Okpechi IG, Ayodele OE, Jones ES, Duffield M, Swanepoel CR.

Nephrol Dial Transplant. 2012 Sep;27(9):3509-15. doi: 10.1093/ndt/gfs122. Epub 2012 May 18.

PMID:
22610989
18.

Clinicopathological insights into lupus nephritis in South Africans: a study of 251 patients.

Okpechi IG, Swanepoel CR, Tiffin N, Duffield M, Rayner BL.

Lupus. 2012 Aug;21(9):1017-24. doi: 10.1177/0961203312441981. Epub 2012 Mar 26.

PMID:
22451603
19.

The spectrum of renal histologies seen in HIV with outcomes, prognostic indicators and clinical correlations.

Wearne N, Swanepoel CR, Boulle A, Duffield MS, Rayner BL.

Nephrol Dial Transplant. 2012 Nov;27(11):4109-18. doi: 10.1093/ndt/gfr702. Epub 2011 Dec 26.

PMID:
22200584
20.

A new 'dual' in the crown for electrochemistry.

Duffield MD, Keating DJ.

J Neurochem. 2011 Dec;119(5):899-900. doi: 10.1111/j.1471-4159.2011.07508.x. No abstract available.

21.

Repetitive common peroneal nerve stimulation increases ankle dorsiflexor motor evoked potentials in incomplete spinal cord lesions.

Thompson AK, Lapallo B, Duffield M, Abel BM, Pomerantz F.

Exp Brain Res. 2011 Apr;210(1):143-52. doi: 10.1007/s00221-011-2607-1. Epub 2011 Mar 1.

PMID:
21360230
22.

Yersinia pseudotuberculosis mntH functions in intracellular manganese accumulation, which is essential for virulence and survival in cells expressing functional Nramp1.

Champion OL, Karlyshev A, Cooper IA, Ford DC, Wren BW, Duffield M, Oyston PC, Titball RW.

Microbiology. 2011 Apr;157(Pt 4):1115-22. doi: 10.1099/mic.0.045807-0. Epub 2010 Dec 23.

PMID:
21183572
23.

Patterns of renal disease in Cape Town South Africa: a 10-year review of a single-centre renal biopsy database.

Okpechi I, Swanepoel C, Duffield M, Mahala B, Wearne N, Alagbe S, Barday Z, Arendse C, Rayner B.

Nephrol Dial Transplant. 2011 Jun;26(6):1853-61. doi: 10.1093/ndt/gfq655. Epub 2010 Oct 27.

PMID:
20980357
24.

Predicting conserved essential genes in bacteria: in silico identification of putative drug targets.

Duffield M, Cooper I, McAlister E, Bayliss M, Ford D, Oyston P.

Mol Biosyst. 2010 Dec;6(12):2482-9. doi: 10.1039/c0mb00001a. Epub 2010 Oct 14.

PMID:
20949199
25.

Steps toward broad-spectrum therapeutics: discovering virulence-associated genes present in diverse human pathogens.

Stubben CJ, Duffield ML, Cooper IA, Ford DC, Gans JD, Karlyshev AV, Lingard B, Oyston PC, de Rochefort A, Song J, Wren BW, Titball RW, Wolinsky M.

BMC Genomics. 2009 Oct 29;10:501. doi: 10.1186/1471-2164-10-501.

26.

A Burkholderia pseudomallei protein microarray reveals serodiagnostic and cross-reactive antigens.

Felgner PL, Kayala MA, Vigil A, Burk C, Nakajima-Sasaki R, Pablo J, Molina DM, Hirst S, Chew JS, Wang D, Tan G, Duffield M, Yang R, Neel J, Chantratita N, Bancroft G, Lertmemongkolchai G, Davies DH, Baldi P, Peacock S, Titball RW.

Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13499-504. doi: 10.1073/pnas.0812080106. Epub 2009 Jul 28.

27.

Complement C3 plays an essential role in the control of opportunistic fungal infections.

Tsoni SV, Kerrigan AM, Marakalala MJ, Srinivasan N, Duffield M, Taylor PR, Botto M, Steele C, Brown GD.

Infect Immun. 2009 Sep;77(9):3679-85. doi: 10.1128/IAI.00233-09. Epub 2009 Jul 6.

28.

Proteins accessible to immune surveillance show significant T-cell epitope depletion: Implications for vaccine design.

Halling-Brown M, Shaban R, Frampton D, Sansom CE, Davies M, Flower D, Duffield M, Titball RW, Brusic V, Moss DS.

Mol Immunol. 2009 Aug;46(13):2699-705. doi: 10.1016/j.molimm.2009.05.027. Epub 2009 Jun 27.

PMID:
19560824
29.

Galleria mellonella as an alternative infection model for Yersinia pseudotuberculosis.

Champion OL, Cooper IA, James SL, Ford D, Karlyshev A, Wren BW, Duffield M, Oyston PC, Titball RW.

Microbiology. 2009 May;155(Pt 5):1516-22. doi: 10.1099/mic.0.026823-0. Epub 2009 Apr 21.

PMID:
19383703
30.

Clinical and pathological features of hereditary mixed polyposis syndrome: report on a South African family.

Ibirogba SB, Algar U, Goldberg PA, Duffield M, Vorster A, Ramesar R.

S Afr J Surg. 2008 Aug;46(3):90-2.

PMID:
18807306
31.

Analysis of known bacterial protein vaccine antigens reveals biased physical properties and amino acid composition.

Mayers C, Duffield M, Rowe S, Miller J, Lingard B, Hayward S, Titball RW.

Comp Funct Genomics. 2003;4(5):468-78. doi: 10.1002/cfg.319.

32.

From protein microarrays to diagnostic antigen discovery: a study of the pathogen Francisella tularensis.

Sundaresh S, Randall A, Unal B, Petersen JM, Belisle JT, Hartley MG, Duffield M, Titball RW, Davies DH, Felgner PL, Baldi P.

Bioinformatics. 2007 Jul 1;23(13):i508-18.

PMID:
17646338
33.

Vocal cord paralysis secondary to multinodular goiter.

Mulwafu W, Panieri E, Garb M, Duffield M.

S Afr Med J. 2006 Nov;96(11):1176-7. No abstract available.

34.

Down-regulation of gene transcripts associated with ricin tolerance in human RPMI 2650 cells.

Wilkinson LJ, Duffield ML, Titball RW, Lindsay CD.

Toxicol In Vitro. 2007 Apr;21(3):509-20. Epub 2006 Nov 6.

PMID:
17166693
35.

The identification and evaluation of ATP binding cassette systems in the intracellular bacterium Francisella tularensis.

Atkins HS, Dassa E, Walker NJ, Griffin KF, Harland DN, Taylor RR, Duffield ML, Titball RW.

Res Microbiol. 2006 Jul-Aug;157(6):593-604. Epub 2006 Feb 8.

PMID:
16503121
36.

Living donor liver transplantation--adult donor outcomes: a systematic review.

Middleton PF, Duffield M, Lynch SV, Padbury RT, House T, Stanton P, Verran D, Maddern G.

Liver Transpl. 2006 Jan;12(1):24-30. Review.

PMID:
16498709
37.

Zinc inhibits human ClC-1 muscle chloride channel by interacting with its common gating mechanism.

Duffield MD, Rychkov GY, Bretag AH, Roberts ML.

J Physiol. 2005 Oct 1;568(Pt 1):5-12. Epub 2005 Jul 7.

38.

The complete genome sequence of Francisella tularensis, the causative agent of tularemia.

Larsson P, Oyston PC, Chain P, Chu MC, Duffield M, Fuxelius HH, Garcia E, Hälltorp G, Johansson D, Isherwood KE, Karp PD, Larsson E, Liu Y, Michell S, Prior J, Prior R, Malfatti S, Sjöstedt A, Svensson K, Thompson N, Vergez L, Wagg JK, Wren BW, Lindler LE, Andersson SG, Forsman M, Titball RW.

Nat Genet. 2005 Feb;37(2):153-9. Epub 2005 Jan 9.

PMID:
15640799
39.

Renal tubular toxicity of HMG-CoA reductase inhibitors.

van Zyl-Smit R, Firth JC, Duffield M, Marais AD.

Nephrol Dial Transplant. 2004 Dec;19(12):3176-9. No abstract available.

PMID:
15575008
40.

Characterization of a CD46 transgenic pig and protection of transgenic kidneys against hyperacute rejection in non-immunosuppressed baboons.

Loveland BE, Milland J, Kyriakou P, Thorley BR, Christiansen D, Lanteri MB, Regensburg M, Duffield M, French AJ, Williams L, Baker L, Brandon MR, Xing PX, Kahn D, McKenzie IF.

Xenotransplantation. 2004 Mar;11(2):171-83.

PMID:
14962279
41.

Involvement of helices at the dimer interface in ClC-1 common gating.

Duffield M, Rychkov G, Bretag A, Roberts M.

J Gen Physiol. 2003 Feb;121(2):149-61.

42.

Governing the borderlands: decoding the power of aid.

Duffield M.

Disasters. 2001 Dec;25(4):308-20.

PMID:
11780856
43.

Politics and humanitarian aid.

Duffield M, Macrae J, Curtis D.

Disasters. 2001 Dec;25(4):269-74. No abstract available.

PMID:
11780853
44.

Microsporidiosis in the graft of a renal transplant recipient.

Latib MA, Pascoe MD, Duffield MS, Kahn D.

Transpl Int. 2001 Aug;14(4):274-7.

PMID:
11512063
45.

Molecular epidemiology of HIV type 1 in a rural community in southwest Uganda.

Kaleebu P, Whitworth J, Hamilton L, Rutebemberwa A, Lyagoba F, Morgan D, Duffield M, Biryahwaho B, Magambo B, Oram J.

AIDS Res Hum Retroviruses. 2000 Mar 20;16(5):393-401.

PMID:
10772525
46.

Novel attributes of an androgenic steroid-mediated increase in cardiac end diastolic stiffness in rats.

Trifunovic B, Woodiwiss AJ, Duffield M, Norton GR.

Can J Physiol Pharmacol. 1998 Jun;76(6):657-64.

PMID:
9923404
47.

Changes in T-cell subsets after renal transplantation in nonimmunosuppressed baboons.

Linley W, Davison G, Smit JA, Shephard E, Duffield M, Finlayson J, McKenzie IF, Kahn D.

Transplant Proc. 1998 Jun;30(4):1163. No abstract available.

PMID:
9636469
48.
49.
50.

PAPNET automated screening.

Whittaker J, Cruse P, Denny L, Dehaeck K, Soeters R, Duffield M, Bloch B, Wranz P, MacCallum S.

S Afr Med J. 1996 Mar;86(3):273-4. No abstract available.

PMID:
8658306

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