Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 116

1.

Deletion of the Mitochondrial Complex-IV Cofactor Heme A:Farnesyltransferase Causes Focal Segmental Glomerulosclerosis and Interferon Response.

Baek JH, Gomez IG, Wada Y, Roach A, Mahad D, Duffield JS.

Am J Pathol. 2018 Dec;188(12):2745-2762. doi: 10.1016/j.ajpath.2018.08.018. Epub 2018 Sep 28.

PMID:
30268775
2.

Kidney-resident macrophages promote a proangiogenic environment in the normal and chronically ischemic mouse kidney.

Puranik AS, Leaf IA, Jensen MA, Hedayat AF, Saad A, Kim KW, Saadalla AM, Woollard JR, Kashyap S, Textor SC, Grande JP, Lerman A, Simari RD, Randolph GJ, Duffield JS, Lerman LO.

Sci Rep. 2018 Sep 17;8(1):13948. doi: 10.1038/s41598-018-31887-4.

3.

Interleukin-1β Activates a MYC-Dependent Metabolic Switch in Kidney Stromal Cells Necessary for Progressive Tubulointerstitial Fibrosis.

Lemos DR, McMurdo M, Karaca G, Wilflingseder J, Leaf IA, Gupta N, Miyoshi T, Susa K, Johnson BG, Soliman K, Wang G, Morizane R, Bonventre JV, Duffield JS.

J Am Soc Nephrol. 2018 Jun;29(6):1690-1705. doi: 10.1681/ASN.2017121283. Epub 2018 May 8.

4.

Tissue-resident mesenchymal stromal cells: Implications for tissue-specific antifibrotic therapies.

Lemos DR, Duffield JS.

Sci Transl Med. 2018 Jan 31;10(426). pii: eaan5174. doi: 10.1126/scitranslmed.aan5174. Review.

PMID:
29386358
5.

Uromodulin p.Cys147Trp mutation drives kidney disease by activating ER stress and apoptosis.

Johnson BG, Dang LT, Marsh G, Roach AM, Levine ZG, Monti A, Reyon D, Feigenbaum L, Duffield JS.

J Clin Invest. 2017 Nov 1;127(11):3954-3969. doi: 10.1172/JCI93817. Epub 2017 Oct 9.

6.

TIMP3 is Regulated by Pericytes upon Shear Stress Detection Leading to a Modified Endothelial Cell Response.

Schrimpf C, Koppen T, Duffield JS, Böer U, David S, Ziegler W, Haverich A, Teebken OE, Wilhelmi M.

Eur J Vasc Endovasc Surg. 2017 Oct;54(4):524-533. doi: 10.1016/j.ejvs.2017.07.002. Epub 2017 Aug 12.

7.

Hyperactive FOXO1 results in lack of tip stalk identity and deficient microvascular regeneration during kidney injury.

Dang LTH, Aburatani T, Marsh GA, Johnson BG, Alimperti S, Yoon CJ, Huang A, Szak S, Nakagawa N, Gomez I, Ren S, Read SK, Sparages C, Aplin AC, Nicosia RF, Chen C, Ligresti G, Duffield JS.

Biomaterials. 2017 Oct;141:314-329. doi: 10.1016/j.biomaterials.2017.07.010. Epub 2017 Jul 7.

8.

What can target kidney fibrosis?

Leaf IA, Duffield JS.

Nephrol Dial Transplant. 2017 Jan 1;32(suppl_1):i89-i97. doi: 10.1093/ndt/gfw388. Review.

PMID:
28391346
9.

Serelaxin as a potential treatment for renal dysfunction in cirrhosis: Preclinical evaluation and results of a randomized phase 2 trial.

Snowdon VK, Lachlan NJ, Hoy AM, Hadoke PW, Semple SI, Patel D, Mungall W, Kendall TJ, Thomson A, Lennen RJ, Jansen MA, Moran CM, Pellicoro A, Ramachandran P, Shaw I, Aucott RL, Severin T, Saini R, Pak J, Yates D, Dongre N, Duffield JS, Webb DJ, Iredale JP, Hayes PC, Fallowfield JA.

PLoS Med. 2017 Feb 28;14(2):e1002248. doi: 10.1371/journal.pmed.1002248. eCollection 2017 Feb.

10.

Lung pericyte-like cells are functional interstitial immune sentinel cells.

Hung CF, Mittelsteadt KL, Brauer R, McKinney BL, Hallstrand TS, Parks WC, Chen P, Schnapp LM, Liles WC, Duffield JS, Altemeier WA.

Am J Physiol Lung Cell Mol Physiol. 2017 Apr 1;312(4):L556-L567. doi: 10.1152/ajplung.00349.2016. Epub 2017 Feb 10.

11.

Connective Tissue Growth Factor Domain 4 Amplifies Fibrotic Kidney Disease through Activation of LDL Receptor-Related Protein 6.

Johnson BG, Ren S, Karaca G, Gomez IG, Fligny C, Smith B, Ergun A, Locke G, Gao B, Hayes S, MacDonnell S, Duffield JS.

J Am Soc Nephrol. 2017 Jun;28(6):1769-1782. doi: 10.1681/ASN.2016080826. Epub 2017 Jan 27.

12.

Inhibition of αvβ5 Integrin Attenuates Vascular Permeability and Protects against Renal Ischemia-Reperfusion Injury.

McCurley A, Alimperti S, Campos-Bilderback SB, Sandoval RM, Calvino JE, Reynolds TL, Quigley C, Mugford JW, Polacheck WJ, Gomez IG, Dovey J, Marsh G, Huang A, Qian F, Weinreb PH, Dolinski BM, Moore S, Duffield JS, Chen CS, Molitoris BA, Violette SM, Crackower MA.

J Am Soc Nephrol. 2017 Jun;28(6):1741-1752. doi: 10.1681/ASN.2016020200. Epub 2017 Jan 6.

13.

Pericytes and immune cells contribute to complement activation in tubulointerstitial fibrosis.

Xavier S, Sahu RK, Landes SG, Yu J, Taylor RP, Ayyadevara S, Megyesi J, Stallcup WB, Duffield JS, Reis ES, Lambris JD, Portilla D.

Am J Physiol Renal Physiol. 2017 Mar 1;312(3):F516-F532. doi: 10.1152/ajprenal.00604.2016. Epub 2017 Jan 4.

14.

Pentraxin-2 suppresses c-Jun/AP-1 signaling to inhibit progressive fibrotic disease.

Nakagawa N, Barron L, Gomez IG, Johnson BG, Roach AM, Kameoka S, Jack RM, Lupher ML Jr, Gharib SA, Duffield JS.

JCI Insight. 2016 Dec 8;1(20):e87446. doi: 10.1172/jci.insight.87446.

15.

Lysophosphatidic acid signaling through its receptor initiates profibrotic epithelial cell fibroblast communication mediated by epithelial cell derived connective tissue growth factor.

Sakai N, Chun J, Duffield JS, Lagares D, Wada T, Luster AD, Tager AM.

Kidney Int. 2017 Mar;91(3):628-641. doi: 10.1016/j.kint.2016.09.030. Epub 2016 Dec 4.

16.

Pericyte MyD88 and IRAK4 control inflammatory and fibrotic responses to tissue injury.

Leaf IA, Nakagawa S, Johnson BG, Cha JJ, Mittelsteadt K, Guckian KM, Gomez IG, Altemeier WA, Duffield JS.

J Clin Invest. 2017 Jan 3;127(1):321-334. doi: 10.1172/JCI87532. Epub 2016 Nov 21.

17.

PDGFRα signalling promotes fibrogenic responses in collagen-producing cells in Duchenne muscular dystrophy.

Ieronimakis N, Hays A, Prasad A, Janebodin K, Duffield JS, Reyes M.

J Pathol. 2016 Dec;240(4):410-424. doi: 10.1002/path.4801. Epub 2016 Oct 20.

18.

Lung Pericytes and Resident Fibroblasts: Busy Multitaskers.

Barron L, Gharib SA, Duffield JS.

Am J Pathol. 2016 Oct;186(10):2519-31. doi: 10.1016/j.ajpath.2016.07.004. Epub 2016 Aug 21. Review.

19.

Beyond EMT: Epithelial STAT3 as a Central Regulator of Fibrogenesis.

Duffield JS.

J Am Soc Nephrol. 2016 Dec;27(12):3502-3504. Epub 2016 Jul 1. No abstract available.

20.

Maintenance of vascular integrity by pericytes is essential for normal kidney function.

Lemos DR, Marsh G, Huang A, Campanholle G, Aburatani T, Dang L, Gomez I, Fisher K, Ligresti G, Peti-Peterdi J, Duffield JS.

Am J Physiol Renal Physiol. 2016 Dec 1;311(6):F1230-F1242. doi: 10.1152/ajprenal.00030.2016. Epub 2016 Jun 22.

21.

TWEAK-Fn14 Signaling Activates Myofibroblasts to Drive Progression of Fibrotic Kidney Disease.

Gomez IG, Roach AM, Nakagawa N, Amatucci A, Johnson BG, Dunn K, Kelly MC, Karaca G, Zheng TS, Szak S, Peppiatt-Wildman CM, Burkly LC, Duffield JS.

J Am Soc Nephrol. 2016 Dec;27(12):3639-3652. Epub 2016 Mar 29.

22.

MicroRNAs as novel therapeutic targets to treat kidney injury and fibrosis.

Gomez IG, Nakagawa N, Duffield JS.

Am J Physiol Renal Physiol. 2016 May 1;310(10):F931-44. doi: 10.1152/ajprenal.00523.2015. Epub 2016 Feb 24. Review.

23.

Nonhematopoietic Peroxisome Proliferator-Activated Receptor-α Protects Against Cardiac Injury and Enhances Survival in Experimental Polymicrobial Sepsis.

Standage SW, Waworuntu RL, Delaney MA, Maskal SM, Bennion BG, Duffield JS, Parks WC, Liles WC, McGuire JK.

Crit Care Med. 2016 Aug;44(8):e594-603. doi: 10.1097/CCM.0000000000001585.

24.

Cells of renin lineage express hypoxia inducible factor 2α following experimental ureteral obstruction.

Stefanska A, Eng D, Kaverina N, Pippin JW, Gross KW, Duffield JS, Shankland SJ.

BMC Nephrol. 2016 Jan 8;17:5. doi: 10.1186/s12882-015-0216-0.

25.

A Novel Three-Dimensional Human Peritubular Microvascular System.

Ligresti G, Nagao RJ, Xue J, Choi YJ, Xu J, Ren S, Aburatani T, Anderson SK, MacDonald JW, Bammler TK, Schwartz SM, Muczynski KA, Duffield JS, Himmelfarb J, Zheng Y.

J Am Soc Nephrol. 2016 Aug;27(8):2370-81. doi: 10.1681/ASN.2015070747. Epub 2015 Dec 11.

26.

The FOXD1 lineage of kidney perivascular cells and myofibroblasts: functions and responses to injury.

Gomez IG, Duffield JS.

Kidney Int Suppl (2011). 2014 Nov;4(1):26-33. Review.

27.

Interstitial pericytes decrease in aged mouse kidneys.

Stefanska A, Eng D, Kaverina N, Duffield JS, Pippin JW, Rabinovitch P, Shankland SJ.

Aging (Albany NY). 2015 Jun;7(6):370-82.

28.

Cells of renin lineage are adult pluripotent progenitors in experimental glomerular disease.

Pippin JW, Kaverina NV, Eng DG, Krofft RD, Glenn ST, Duffield JS, Gross KW, Shankland SJ.

Am J Physiol Renal Physiol. 2015 Aug 15;309(4):F341-58. doi: 10.1152/ajprenal.00438.2014. Epub 2015 Jun 10.

29.

Granulocyte/Macrophage Colony-stimulating Factor-dependent Dendritic Cells Restrain Lean Adipose Tissue Expansion.

Pamir N, Liu NC, Irwin A, Becker L, Peng Y, Ronsein GE, Bornfeldt KE, Duffield JS, Heinecke JW.

J Biol Chem. 2015 Jun 5;290(23):14656-67. doi: 10.1074/jbc.M115.645820. Epub 2015 Apr 30.

30.

Dicer1 activity in the stromal compartment regulates nephron differentiation and vascular patterning during mammalian kidney organogenesis.

Nakagawa N, Xin C, Roach AM, Naiman N, Shankland SJ, Ligresti G, Ren S, Szak S, Gomez IG, Duffield JS.

Kidney Int. 2015 Jun;87(6):1125-40. doi: 10.1038/ki.2014.406. Epub 2015 Feb 4.

31.

Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways.

Gomez IG, MacKenna DA, Johnson BG, Kaimal V, Roach AM, Ren S, Nakagawa N, Xin C, Newitt R, Pandya S, Xia TH, Liu X, Borza DB, Grafals M, Shankland SJ, Himmelfarb J, Portilla D, Liu S, Chau BN, Duffield JS.

J Clin Invest. 2015 Jan;125(1):141-56. doi: 10.1172/JCI75852. Epub 2014 Nov 21.

32.

Deficient Autophagy Results in Mitochondrial Dysfunction and FSGS.

Kawakami T, Gomez IG, Ren S, Hudkins K, Roach A, Alpers CE, Shankland SJ, D'Agati VD, Duffield JS.

J Am Soc Nephrol. 2015 May;26(5):1040-52. doi: 10.1681/ASN.2013111202. Epub 2014 Nov 18.

33.

Progenitor cells and podocyte regeneration.

Shankland SJ, Pippin JW, Duffield JS.

Semin Nephrol. 2014 Jul;34(4):418-28. doi: 10.1016/j.semnephrol.2014.06.008. Epub 2014 Jun 13. Review.

34.

The role of pericyte detachment in vascular rarefaction.

Schrimpf C, Teebken OE, Wilhelmi M, Duffield JS.

J Vasc Res. 2014;51(4):247-58. doi: 10.1159/000365149. Epub 2014 Sep 3. Review.

35.

MicroRNAs are potential therapeutic targets in fibrosing kidney disease: lessons from animal models.

Duffield JS, Grafals M, Portilla D.

Drug Discov Today Dis Models. 2013 Fall;10(3):e127-e135.

36.

Cellular and molecular mechanisms in kidney fibrosis.

Duffield JS.

J Clin Invest. 2014 Jun;124(6):2299-306. doi: 10.1172/JCI72267. Epub 2014 Jun 2. Review.

37.

Lineage tracing reveals distinctive fates for mesothelial cells and submesothelial fibroblasts during peritoneal injury.

Chen YT, Chang YT, Pan SY, Chou YH, Chang FC, Yeh PY, Liu YH, Chiang WC, Chen YM, Wu KD, Tsai TJ, Duffield JS, Lin SL.

J Am Soc Nephrol. 2014 Dec;25(12):2847-58. doi: 10.1681/ASN.2013101079. Epub 2014 May 22.

38.

Translational profiles of medullary myofibroblasts during kidney fibrosis.

Grgic I, Krautzberger AM, Hofmeister A, Lalli M, DiRocco DP, Fleig SV, Liu J, Duffield JS, McMahon AP, Aronow B, Humphreys BD.

J Am Soc Nephrol. 2014 Sep;25(9):1979-90. doi: 10.1681/ASN.2013101143. Epub 2014 Mar 20.

39.

Cells of renin lineage take on a podocyte phenotype in aging nephropathy.

Pippin JW, Glenn ST, Krofft RD, Rusiniak ME, Alpers CE, Hudkins K, Duffield JS, Gross KW, Shankland SJ.

Am J Physiol Renal Physiol. 2014 May 15;306(10):F1198-209. doi: 10.1152/ajprenal.00699.2013. Epub 2014 Mar 19.

40.

Innovations in preclinical biology: ex vivo engineering of a human kidney tissue microperfusion system.

Kelly EJ, Wang Z, Voellinger JL, Yeung CK, Shen DD, Thummel KE, Zheng Y, Ligresti G, Eaton DL, Muczynski KA, Duffield JS, Neumann T, Tourovskaia A, Fauver M, Kramer G, Asp E, Himmelfarb J.

Stem Cell Res Ther. 2013;4 Suppl 1:S17. doi: 10.1186/scrt378. Epub 2013 Dec 20. Review.

41.

Chronic Ifosfamide toxicity: kidney pathology and pathophysiology.

Akilesh S, Juaire N, Duffield JS, Smith KD.

Am J Kidney Dis. 2014 May;63(5):843-50. doi: 10.1053/j.ajkd.2013.11.028. Epub 2014 Feb 8. Erratum in: Am J Kidney Dis. 2014 Oct;64(4):666.

PMID:
24518127
42.

Myofibroblasts in Fibrotic Kidneys.

Nakagawa N, Duffield JS.

Curr Pathobiol Rep. 2013 Sep 1;1(3). doi: 10.1007/s40139-013-0025-8.

43.

Cysteamine modulates oxidative stress and blocks myofibroblast activity in CKD.

Okamura DM, Bahrami NM, Ren S, Pasichnyk K, Williams JM, Gangoiti JA, Lopez-Guisa JM, Yamaguchi I, Barshop BA, Duffield JS, Eddy AA.

J Am Soc Nephrol. 2014 Jan;25(1):43-54. doi: 10.1681/ASN.2012090962. Epub 2013 Sep 5.

44.

Resident renal mononuclear phagocytes comprise five discrete populations with distinct phenotypes and functions.

Kawakami T, Lichtnekert J, Thompson LJ, Karna P, Bouabe H, Hohl TM, Heinecke JW, Ziegler SF, Nelson PJ, Duffield JS.

J Immunol. 2013 Sep 15;191(6):3358-72. doi: 10.4049/jimmunol.1300342. Epub 2013 Aug 16.

45.

Role of lung pericytes and resident fibroblasts in the pathogenesis of pulmonary fibrosis.

Hung C, Linn G, Chow YH, Kobayashi A, Mittelsteadt K, Altemeier WA, Gharib SA, Schnapp LM, Duffield JS.

Am J Respir Crit Care Med. 2013 Oct 1;188(7):820-30. doi: 10.1164/rccm.201212-2297OC.

46.

Coronary adventitial cells are linked to perivascular cardiac fibrosis via TGFβ1 signaling in the mdx mouse model of Duchenne muscular dystrophy.

Ieronimakis N, Hays AL, Janebodin K, Mahoney WM Jr, Duffield JS, Majesky MW, Reyes M.

J Mol Cell Cardiol. 2013 Oct;63:122-34. doi: 10.1016/j.yjmcc.2013.07.014. Epub 2013 Aug 1.

47.

Pregnancy-associated polyuria in familial renal glycosuria.

Toka HR, Yang J, Zera CA, Duffield JS, Pollak MR, Mount DB.

Am J Kidney Dis. 2013 Dec;62(6):1160-4. doi: 10.1053/j.ajkd.2013.05.018. Epub 2013 Jul 18.

PMID:
23871407
48.

TLR-2/TLR-4 TREM-1 signaling pathway is dispensable in inflammatory myeloid cells during sterile kidney injury.

Campanholle G, Mittelsteadt K, Nakagawa S, Kobayashi A, Lin SL, Gharib SA, Heinecke JW, Hamerman JA, Altemeier WA, Duffield JS.

PLoS One. 2013 Jul 3;8(7):e68640. doi: 10.1371/journal.pone.0068640. Print 2013.

49.

Proximal tubule PPARα attenuates renal fibrosis and inflammation caused by unilateral ureteral obstruction.

Li S, Mariappan N, Megyesi J, Shank B, Kannan K, Theus S, Price PM, Duffield JS, Portilla D.

Am J Physiol Renal Physiol. 2013 Sep 1;305(5):F618-27. doi: 10.1152/ajprenal.00309.2013. Epub 2013 Jun 26.

50.

Cells of renin lineage are progenitors of podocytes and parietal epithelial cells in experimental glomerular disease.

Pippin JW, Sparks MA, Glenn ST, Buitrago S, Coffman TM, Duffield JS, Gross KW, Shankland SJ.

Am J Pathol. 2013 Aug;183(2):542-57. doi: 10.1016/j.ajpath.2013.04.024. Epub 2013 Jun 14.

Supplemental Content

Loading ...
Support Center