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Items: 10

1.

Elagolix Alone or With Add-Back Therapy in Women With Heavy Menstrual Bleeding and Uterine Leiomyomas: A Randomized Controlled Trial.

Carr BR, Stewart EA, Archer DF, Al-Hendy A, Bradley L, Watts NB, Diamond MP, Gao J, Owens CD, Chwalisz K, Duan WR, Soliman AM, Dufek MB, Simon JA.

Obstet Gynecol. 2018 Nov;132(5):1252-1264. doi: 10.1097/AOG.0000000000002933.

PMID:
30303923
2.

Efficacy and safety of paricalcitol in children with stages 3 to 5 chronic kidney disease.

Webb NJA, Lerner G, Warady BA, Dell KM, Greenbaum LA, Ariceta G, Hoppe B, Linde P, Lee HJ, Eldred A, Dufek MB.

Pediatr Nephrol. 2017 Jul;32(7):1221-1232. doi: 10.1007/s00467-017-3579-6. Epub 2017 Mar 22.

3.

Intestinal first-pass metabolism by cytochrome p450 and not p-glycoprotein is the major barrier to amprenavir absorption.

Dufek MB, Bridges AS, Thakker DR.

Drug Metab Dispos. 2013 Sep;41(9):1695-702. doi: 10.1124/dmd.113.052191. Epub 2013 Jul 2.

PMID:
23821186
4.

P-glycoprotein increases portal bioavailability of loperamide in mouse by reducing first-pass intestinal metabolism.

Dufek MB, Knight BM, Bridges AS, Thakker DR.

Drug Metab Dispos. 2013 Mar;41(3):642-50. doi: 10.1124/dmd.112.049965. Epub 2013 Jan 3.

PMID:
23288866
5.

Daily dosing of vismodegib to steady state does not prolong the QTc interval in healthy volunteers.

Graham RA, Chang I, Jin JY, Wang B, Dufek MB, Ayache JA, Ezzet F, Zerivitz K, Low JA, Dresser MJ.

J Cardiovasc Pharmacol. 2013 Jan;61(1):83-9. doi: 10.1097/FJC.0b013e3182793ac9.

PMID:
23107871
6.

Effects of maternal intravenous nicotine administration on locomotor behavior in pre-weanling rats.

LeSage MG, Gustaf E, Dufek MB, Pentel PR.

Pharmacol Biochem Behav. 2006 Nov;85(3):575-83. Epub 2006 Dec 4.

7.

Vaccination against nicotine does not prevent nicotine-induced changes in fetal nicotinic receptor binding and c-fos mRNA expression in rats.

Pentel PR, Keyler DE, Chen Y, LeSage MG, Dufek MB, Le C, Leslie FM.

Neurotoxicol Teratol. 2006 Sep-Oct;28(5):589-96. Epub 2006 Aug 15.

PMID:
16996246
8.

Changes in maternal and fetal nicotine distribution after maternal administration of monoclonal nicotine-specific antibody to rats.

Keyler DE, Lesage MG, Dufek MB, Pentel PR.

Int Immunopharmacol. 2006 Nov;6(11):1665-72. Epub 2006 Aug 4.

9.

Differential effects of passive immunization with nicotine-specific antibodies on the acute and chronic distribution of nicotine to brain in rats.

Pentel PR, Dufek MB, Roiko SA, Lesage MG, Keyler DE.

J Pharmacol Exp Ther. 2006 May;317(2):660-6. Epub 2006 Jan 11.

PMID:
16407464
10.

Reduced nicotine distribution from mother to fetal brain in rats vaccinated against nicotine: time course and influence of nicotine dosing regimen.

Keyler DE, Dufek MB, Calvin AD, Bramwell TJ, LeSage MG, Raphael DE, Ross CA, Le CT, Pentel PR.

Biochem Pharmacol. 2005 May 1;69(9):1385-95.

PMID:
15826609

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