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Items: 17


Targeting DDR2 enhances tumor response to anti-PD-1 immunotherapy.

Tu MM, Lee FYF, Jones RT, Kimball AK, Saravia E, Graziano RF, Coleman B, Menard K, Yan J, Michaud E, Chang H, Abdel-Hafiz HA, Rozhok AI, Duex JE, Agarwal N, Chauca-Diaz A, Johnson LK, Ng TL, Cambier JC, Clambey ET, Costello JC, Korman AJ, Theodorescu D.

Sci Adv. 2019 Feb 20;5(2):eaav2437. doi: 10.1126/sciadv.aav2437. eCollection 2019 Feb.


Functional Impact of Chromatin Remodeling Gene Mutations and Predictive Signature for Therapeutic Response in Bladder Cancer.

Duex JE, Swain KE, Dancik GM, Paucek RD, Owens C, Churchill MEA, Theodorescu D.

Mol Cancer Res. 2018 Jan;16(1):69-77. doi: 10.1158/1541-7786.MCR-17-0260. Epub 2017 Oct 2.


Nuclear CD24 Drives Tumor Growth and Is Predictive of Poor Patient Prognosis.

Duex JE, Owens C, Chauca-Diaz A, Dancik GM, Vanderlinden LA, Ghosh D, Leivo MZ, Hansel DE, Theodorescu D.

Cancer Res. 2017 Sep 15;77(18):4858-4867. doi: 10.1158/0008-5472.CAN-17-0367. Epub 2017 Jul 3.


GON4L Drives Cancer Growth through a YY1-Androgen Receptor-CD24 Axis.

Agarwal N, Dancik GM, Goodspeed A, Costello JC, Owens C, Duex JE, Theodorescu D.

Cancer Res. 2016 Sep 1;76(17):5175-85. doi: 10.1158/0008-5472.CAN-16-1099. Epub 2016 Jun 16.


Patient Mutation Directed shRNA Screen Uncovers Novel Bladder Tumor Growth Suppressors.

Hensel J, Duex JE, Owens C, Dancik GM, Edwards MG, Frierson HF, Theodorescu D.

Mol Cancer Res. 2015 Sep;13(9):1306-15. doi: 10.1158/1541-7786.MCR-15-0130. Epub 2015 Jun 15.


Role in tumor growth of a glycogen debranching enzyme lost in glycogen storage disease.

Guin S, Pollard C, Ru Y, Ritterson Lew C, Duex JE, Dancik G, Owens C, Spencer A, Knight S, Holemon H, Gupta S, Hansel D, Hellerstein M, Lorkiewicz P, Lane AN, Fan TW, Theodorescu D.

J Natl Cancer Inst. 2014 Apr 3;106(5). pii: dju062. doi: 10.1093/jnci/dju062.


CD24 expression is important in male urothelial tumorigenesis and metastasis in mice and is androgen regulated.

Overdevest JB, Knubel KH, Duex JE, Thomas S, Nitz MD, Harding MA, Smith SC, Frierson HF, Conaway M, Theodorescu D.

Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):E3588-96. doi: 10.1073/pnas.1113960109. Epub 2012 Sep 25.


Usp18 regulates epidermal growth factor (EGF) receptor expression and cancer cell survival via microRNA-7.

Duex JE, Comeau L, Sorkin A, Purow B, Kefas B.

J Biol Chem. 2011 Jul 15;286(28):25377-86. doi: 10.1074/jbc.M111.222760. Epub 2011 May 18.


Recruitment of Uev1B to Hrs-containing endosomes and its effect on endosomal trafficking.

Duex JE, Mullins MR, Sorkin A.

Exp Cell Res. 2010 Aug 1;316(13):2136-51. doi: 10.1016/j.yexcr.2010.04.017. Epub 2010 Apr 24.


Quantitative analysis of endocytosis and turnover of epidermal growth factor (EGF) and EGF receptor.

Sorkin A, Duex JE.

Curr Protoc Cell Biol. 2010 Mar;Chapter 15:Unit 15.14. doi: 10.1002/0471143030.cb1514s46.


RNA interference screen identifies Usp18 as a regulator of epidermal growth factor receptor synthesis.

Duex JE, Sorkin A.

Mol Biol Cell. 2009 Mar;20(6):1833-44. doi: 10.1091/mbc.E08-08-0880. Epub 2009 Jan 21.


VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse.

Jin N, Chow CY, Liu L, Zolov SN, Bronson R, Davisson M, Petersen JL, Zhang Y, Park S, Duex JE, Goldowitz D, Meisler MH, Weisman LS.

EMBO J. 2008 Dec 17;27(24):3221-34. doi: 10.1038/emboj.2008.248. Epub 2008 Nov 27.


The Vac14p-Fig4p complex acts independently of Vac7p and couples PI3,5P2 synthesis and turnover.

Duex JE, Tang F, Weisman LS.

J Cell Biol. 2006 Feb 27;172(5):693-704. Epub 2006 Feb 21.


Osmotic stress-induced increase of phosphatidylinositol 3,5-bisphosphate requires Vac14p, an activator of the lipid kinase Fab1p.

Bonangelino CJ, Nau JJ, Duex JE, Brinkman M, Wurmser AE, Gary JD, Emr SD, Weisman LS.

J Cell Biol. 2002 Mar 18;156(6):1015-28. Epub 2002 Mar 11.


Fusion of docked membranes requires the armadillo repeat protein Vac8p.

Wang YX, Kauffman EJ, Duex JE, Weisman LS.

J Biol Chem. 2001 Sep 14;276(37):35133-40. Epub 2001 Jul 5.


Two distinct regions in a yeast myosin-V tail domain are required for the movement of different cargoes.

Catlett NL, Duex JE, Tang F, Weisman LS.

J Cell Biol. 2000 Aug 7;150(3):513-26.

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