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Items: 1 to 50 of 230

1.

Speciation Theory of Carcinogenesis Explains Karyotypic Individuality and Long Latencies of Cancers.

Hirpara A, Bloomfield M, Duesberg P.

Genes (Basel). 2018 Aug 9;9(8). pii: E402. doi: 10.3390/genes9080402.

2.

Is cancer progression caused by gradual or simultaneous acquisitions of new chromosomes?

Bloomfield M, Duesberg P.

Mol Cytogenet. 2018 Jan 15;11:4. doi: 10.1186/s13039-017-0350-4. eCollection 2018.

3.

Inherent variability of cancer-specific aneuploidy generates metastases.

Bloomfield M, Duesberg P.

Mol Cytogenet. 2016 Dec 16;9:90. doi: 10.1186/s13039-016-0297-x. eCollection 2016.

4.

Karyotype alteration generates the neoplastic phenotypes of SV40-infected human and rodent cells.

Bloomfield M, Duesberg P.

Mol Cytogenet. 2015 Oct 22;8:79. doi: 10.1186/s13039-015-0183-y. eCollection 2015.

5.

Karyotypic evolutions of cancer species in rats during the long latent periods after injection of nitrosourea.

Bloomfield M, McCormack A, Mandrioli D, Fiala C, Aldaz CM, Duesberg P.

Mol Cytogenet. 2014 Dec 16;7(1):71. doi: 10.1186/s13039-014-0071-x. eCollection 2014.

6.

Does aneuploidy destabilize karyotypes automatically?

Duesberg PH.

Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):E974. doi: 10.1073/pnas.1401413111. Epub 2014 Feb 25. No abstract available.

7.

Individual karyotypes at the origins of cervical carcinomas.

McCormack A, Fan JL, Duesberg M, Bloomfield M, Fiala C, Duesberg P.

Mol Cytogenet. 2013 Oct 17;6(1):44. doi: 10.1186/1755-8166-6-44.

8.

Immortality of cancers: a consequence of inherent karyotypic variations and selections for autonomy.

Duesberg P, McCormack A.

Cell Cycle. 2013 Mar 1;12(5):783-802. doi: 10.4161/cc.23720. Epub 2013 Feb 6.

9.

Origin of metastases: subspecies of cancers generated by intrinsic karyotypic variations.

Duesberg P, Iacobuzio-Donahue C, Brosnan JA, McCormack A, Mandrioli D, Chen L.

Cell Cycle. 2012 Mar 15;11(6):1151-66. doi: 10.4161/cc.11.6.19580. Epub 2012 Mar 15.

PMID:
22377695
10.

AIDS since 1984: no evidence for a new, viral epidemic--not even in Africa.

Duesberg PH, Mandrioli D, McCormack A, Nicholson JM, Rasnick D, Fiala C, Koehnlein C, Bauer HH, Ruggiero M.

Ital J Anat Embryol. 2011;116(2):73-92. Review. Erratum in: Ital J Anat Embryol. 2011;116(3):2 p preceding 127.

PMID:
22303636
11.

Is carcinogenesis a form of speciation?

Duesberg P, Mandrioli D, McCormack A, Nicholson JM.

Cell Cycle. 2011 Jul 1;10(13):2100-14. Epub 2011 Jul 1.

PMID:
21666415
12.

Transgenic oncogenes induce oncogene-independent cancers with individual karyotypes and phenotypes.

Klein A, Li N, Nicholson JM, McCormack AA, Graessmann A, Duesberg P.

Cancer Genet Cytogenet. 2010 Jul 15;200(2):79-99. doi: 10.1016/j.cancergencyto.2010.04.008.

PMID:
20620590
13.

Detection of centrosome aberrations in disease-unrelated cells from patients with tumor treated with tyrosine kinase inhibitors.

Giehl M, Leitner A, Haferlach C, Duesberg P, Hofmann WK, Hofheinz R, Seifarth W, Hochhaus A, Fabarius A.

Eur J Haematol. 2010 Aug;85(2):139-48. doi: 10.1111/j.1600-0609.2010.01459.x. Epub 2010 Apr 16.

PMID:
20408871
14.

On the karyotypic origin and evolution of cancer cells.

Nicholson JM, Duesberg P.

Cancer Genet Cytogenet. 2009 Oct 15;194(2):96-110. doi: 10.1016/j.cancergencyto.2009.06.008.

PMID:
19781442
15.

WITHDRAWN: HIV-AIDS hypothesis out of touch with South African AIDS - A new perspective.

Duesberg PH, Nicholson JM, Rasnick D, Fiala C, Bauer HH.

Med Hypotheses. 2009 Jul 19. [Epub ahead of print]

PMID:
19619953
16.

Cancer-causing karyotypes: chromosomal equilibria between destabilizing aneuploidy and stabilizing selection for oncogenic function.

Li L, McCormack AA, Nicholson JM, Fabarius A, Hehlmann R, Sachs RK, Duesberg PH.

Cancer Genet Cytogenet. 2009 Jan 1;188(1):1-25. doi: 10.1016/j.cancergencyto.2008.08.016.

PMID:
19061776
17.

Genomic instability in context of the chromosomal theory.

Fabarius A, Duesberg P, Giehl M, Seifarth W, Hochhaus A, Hehlmann R.

Cell Oncol. 2008;30(6):503-4. No abstract available.

18.

Centrosome aberrations and G1 phase arrest after in vitro and in vivo treatment with the SRC/ABL inhibitor dasatinib.

Fabarius A, Giehl M, Rebacz B, Krämer A, Frank O, Haferlach C, Duesberg P, Hehlmann R, Seifarth W, Hochhaus A.

Haematologica. 2008 Aug;93(8):1145-54. doi: 10.3324/haematol.12793. Epub 2008 Jun 2.

19.

Specific clones of spontaneously evolving karyotypes generate individuality of cancers.

Fabarius A, Li R, Yerganian G, Hehlmann R, Duesberg P.

Cancer Genet Cytogenet. 2008 Jan 15;180(2):89-99. doi: 10.1016/j.cancergencyto.2007.10.006.

PMID:
18206533
20.

Centrosome aberrations after nilotinib and imatinib treatment in vitro are associated with mitotic spindle defects and genetic instability.

Fabarius A, Giehl M, Frank O, Spiess B, Zheng C, Müller MC, Weiss C, Duesberg P, Hehlmann R, Hochhaus A, Seifarth W.

Br J Haematol. 2007 Aug;138(3):369-73.

PMID:
17614824
21.

Chromosomal chaos and cancer.

Duesberg P.

Sci Am. 2007 May;296(5):52-9. No abstract available.

PMID:
17500414
22.

Cancer drug resistance: the central role of the karyotype.

Duesberg P, Li R, Sachs R, Fabarius A, Upender MB, Hehlmann R.

Drug Resist Updat. 2007 Feb-Apr;10(1-2):51-8. Epub 2007 Mar 26. Review.

PMID:
17387035
23.

Aneuploidy and cancer: from correlation to causation.

Duesberg P, Li R, Fabarius A, Hehlmann R.

Contrib Microbiol. 2006;13:16-44. doi: 10.1159/000092963. Review.

PMID:
16627957
24.

The chromosomal basis of cancer.

Duesberg P, Li R, Fabarius A, Hehlmann R.

Cell Oncol. 2005;27(5-6):293-318. Review.

25.

Chromosomal alterations cause the high rates and wide ranges of drug resistance in cancer cells.

Li R, Hehlman R, Sachs R, Duesberg P.

Cancer Genet Cytogenet. 2005 Nov;163(1):44-56.

PMID:
16271955
26.

Induction of centrosome and chromosome aberrations by imatinib in vitro.

Fabarius A, Giehl M, Frank O, Duesberg P, Hochhaus A, Hehlmann R, Seifarth W.

Leukemia. 2005 Sep;19(9):1573-8.

PMID:
15990860
27.

Does aneuploidy or mutation start cancer?

Duesberg P.

Science. 2005 Jan 7;307(5706):41. No abstract available.

PMID:
15637254
28.

Aneuploidy approaching a perfect score in predicting and preventing cancer: highlights from a conference held in Oakland, CA in January, 2004.

Duesberg P, Li R, Rasnick D.

Cell Cycle. 2004 Jun;3(6):823-8. Epub 2004 Jun 20. No abstract available.

PMID:
15197343
29.

Aneuploidy, the primary cause of the multilateral genomic instability of neoplastic and preneoplastic cells.

Duesberg P, Fabarius A, Hehlmann R.

IUBMB Life. 2004 Feb;56(2):65-81. Review.

30.
31.

Are cancers dependent on oncogenes or on aneuploidy?

Duesberg PH.

Cancer Genet Cytogenet. 2003 May;143(1):89-91. No abstract available.

PMID:
12742162
32.

Instability of chromosome structure in cancer cells increases exponentially with degrees of aneuploidy.

Fabarius A, Hehlmann R, Duesberg PH.

Cancer Genet Cytogenet. 2003 May;143(1):59-72.

PMID:
12742157
33.

Multistep carcinogenesis: a chain reaction of aneuploidizations.

Duesberg P, Li R.

Cell Cycle. 2003 May-Jun;2(3):202-10. Review.

PMID:
12734426
34.

Correspondence re: D. Zimonjic et al., Derivation of human tumor cells in vitro without widespread genomic instability. Cancer Res., 61: 8838-8844, 2001.

Li R, Rasnick D, Duesberg P.

Cancer Res. 2002 Nov 1;62(21):6345-8; author reply 6348-9. No abstract available. Erratum in: Cancer Res 2002 Dec 15;62(24):7380.

35.

Specific aneusomies in Chinese hamster cells at different stages of neoplastic transformation, initiated by nitrosomethylurea.

Fabarius A, Willer A, Yerganian G, Hehlmann R, Duesberg P.

Proc Natl Acad Sci U S A. 2002 May 14;99(10):6778-83. Epub 2002 May 7.

36.

Origin of multidrug resistance in cells with and without multidrug resistance genes: chromosome reassortments catalyzed by aneuploidy.

Duesberg P, Stindl R, Hehlmann R.

Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11283-8. Epub 2001 Sep 11.

37.
38.

Aneuploidy, the somatic mutation that makes cancer a species of its own.

Duesberg P, Rasnick D.

Cell Motil Cytoskeleton. 2000 Oct;47(2):81-107. Review.

PMID:
11013390
39.

Aneuploidy precedes and segregates with chemical carcinogenesis.

Duesberg P, Li R, Rasnick D, Rausch C, Willer A, Kraemer A, Yerganian G, Hehlmann R.

Cancer Genet Cytogenet. 2000 Jun;119(2):83-93.

PMID:
10867141
40.

Aneuploidy vs. gene mutation hypothesis of cancer: recent study claims mutation but is found to support aneuploidy.

Li R, Sonik A, Stindl R, Rasnick D, Duesberg P.

Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3236-41.

41.

How aneuploidy may cause cancer and genetic instability.

Duesberg P, Rasnick D, Li R, Winters L, Rausch C, Hehlmann R.

Anticancer Res. 1999 Nov-Dec;19(6A):4887-906. Review.

PMID:
10697602
42.

Are centrosomes or aneuploidy the key to cancer?

Duesberg P.

Science. 1999 Jun 25;284(5423):2091-2. No abstract available.

PMID:
10409065
43.

How aneuploidy affects metabolic control and causes cancer.

Rasnick D, Duesberg PH.

Biochem J. 1999 Jun 15;340 ( Pt 3):621-30.

44.

The AIDS dilemma: drug diseases blamed on a passenger virus.

Duesberg P, Rasnick D.

Genetica. 1998;104(2):85-132. Review.

PMID:
10220905
45.

Genetic instability of cancer cells is proportional to their degree of aneuploidy.

Duesberg P, Rausch C, Rasnick D, Hehlmann R.

Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13692-7.

46.

Aneuploidy correlated 100% with chemical transformation of Chinese hamster cells.

Li R, Yerganian G, Duesberg P, Kraemer A, Willer A, Rausch C, Hehlmann R.

Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14506-11.

47.
49.

Commentary: non-HIV hypotheses must be studied more carefully.

Duesberg P.

BMJ. 1996 Jan 27;312(7025):210-1. No abstract available.

50.

Is HIV the cause of AIDS?

Duesberg PH.

Lancet. 1995 Nov 18;346(8986):1371-2. No abstract available.

PMID:
7475805

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