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Items: 1 to 50 of 57

1.

Engulfment of mast cell secretory granules on skin inflammation boosts dendritic cell migration and priming efficiency.

Dudeck J, Froebel J, Kotrba J, Lehmann CHK, Dudziak D, Speier S, Nedospasov SA, Schraven B, Dudeck A.

J Allergy Clin Immunol. 2018 Oct 17. pii: S0091-6749(18)31443-X. doi: 10.1016/j.jaci.2018.08.052. [Epub ahead of print]

PMID:
30339853
2.

The involvement of Toll-like receptor 9 in the pathogenesis of erosive autoimmune arthritis.

Fischer A, Abdollahi-Roodsaz S, Böhm C, Niederreiter B, Meyer B, Yau ACY, Lönnblom E, Joosten LAB, Koenders M, Lehmann CHK, Dudziak D, Krönke G, Holmdahl R, Steiner G.

J Cell Mol Med. 2018 Sep;22(9):4399-4409. doi: 10.1111/jcmm.13735. Epub 2018 Jul 11.

3.

TILGen: A Program to Investigate Immune Targets in Breast Cancer Patients - First Results on the Influence of Tumor-Infiltrating Lymphocytes.

Würfel F, Erber R, Huebner H, Hein A, Lux MP, Jud S, Kremer A, Kranich H, Mackensen A, Häberle L, Hack CC, Rauh C, Wunderle M, Gaß P, Rabizadeh S, Brandl AL, Langemann H, Volz B, Nabieva N, Schulz-Wendtland R, Dudziak D, Beckmann MW, Hartmann A, Fasching PA, Rübner M.

Breast Care (Basel). 2018 Mar;13(1):8-14. doi: 10.1159/000486949. Epub 2018 Feb 15.

4.

CLEC10A Is a Specific Marker for Human CD1c+ Dendritic Cells and Enhances Their Toll-Like Receptor 7/8-Induced Cytokine Secretion.

Heger L, Balk S, Lühr JJ, Heidkamp GF, Lehmann CHK, Hatscher L, Purbojo A, Hartmann A, Garcia-Martin F, Nishimura SI, Cesnjevar R, Nimmerjahn F, Dudziak D.

Front Immunol. 2018 Apr 27;9:744. doi: 10.3389/fimmu.2018.00744. eCollection 2018.

5.

Lenalidomide enhances MOR202-dependent macrophage-mediated effector functions via the vitamin D pathway.

Busch L, Mougiakakos D, Büttner-Herold M, Müller MJ, Volmer DA, Bach C, Fabri M, Bittenbring JT, Neumann F, Boxhammer R, Nolting J, Bisht S, Böttcher M, Jitschin S, Hoffmann MH, Balzer H, Beier F, Gezer D, Dudziak D, Gelse K, Hennig FF, Pallasch CP, Spriewald B, Mackensen A, Bruns H.

Leukemia. 2018 Nov;32(11):2445-2458. doi: 10.1038/s41375-018-0114-0. Epub 2018 Mar 28.

PMID:
29654274
6.

Monocyte-Derived Signals Activate Human Natural Killer Cells in Response to Leishmania Parasites.

Messlinger H, Sebald H, Heger L, Dudziak D, Bogdan C, Schleicher U.

Front Immunol. 2018 Jan 24;9:24. doi: 10.3389/fimmu.2018.00024. eCollection 2018.

7.

Sweet SIGNs: IgG glycosylation leads the way in IVIG-mediated resolution of inflammation.

Brückner C, Lehmann C, Dudziak D, Nimmerjahn F.

Int Immunol. 2017 Dec 30;29(11):499-509. doi: 10.1093/intimm/dxx053. Review.

PMID:
29300958
8.

Select Clr-g Expression on Activated Dendritic Cells Facilitates Cognate Interaction with a Minor Subset of Splenic NK Cells Expressing the Inhibitory Nkrp1g Receptor.

Friede ME, Leibelt S, Dudziak D, Steinle A.

J Immunol. 2018 Feb 1;200(3):983-996. doi: 10.4049/jimmunol.1701180. Epub 2017 Dec 20.

9.

Human lymphoid organ dendritic cell identity is predominantly dictated by ontogeny, not tissue microenvironment.

Heidkamp GF, Sander J, Lehmann CHK, Heger L, Eissing N, Baranska A, Lühr JJ, Hoffmann A, Reimer KC, Lux A, Söder S, Hartmann A, Zenk J, Ulas T, McGovern N, Alexiou C, Spriewald B, Mackensen A, Schuler G, Schauf B, Forster A, Repp R, Fasching PA, Purbojo A, Cesnjevar R, Ullrich E, Ginhoux F, Schlitzer A, Nimmerjahn F, Schultze JL, Dudziak D.

Sci Immunol. 2016 Dec 16;1(6). pii: eaai7677. doi: 10.1126/sciimmunol.aai7677. Epub 2016 Dec 16.

PMID:
28783692
10.

Tumor location determines tissue-specific recruitment of tumor-associated macrophages and antibody-dependent immunotherapy response.

Lehmann B, Biburger M, Brückner C, Ipsen-Escobedo A, Gordan S, Lehmann C, Voehringer D, Winkler T, Schaft N, Dudziak D, Sirbu H, Weber GF, Nimmerjahn F.

Sci Immunol. 2017 Jan 6;2(7). pii: eaah6413. doi: 10.1126/sciimmunol.aah6413.

PMID:
28783667
11.

The Influence of MHC Class II on B Cell Defects Induced by Invariant Chain/CD74 N-Terminal Fragments.

Schneppenheim J, Loock AC, Hüttl S, Schweizer M, Lüllmann-Rauch R, Oberg HH, Arnold P, Lehmann CHK, Dudziak D, Kabelitz D, Lucius R, Lennon-Duménil AM, Saftig P, Schröder B.

J Immunol. 2017 Jul 1;199(1):172-185. doi: 10.4049/jimmunol.1601533. Epub 2017 May 26.

12.

DC subset-specific induction of T cell responses upon antigen uptake via Fcγ receptors in vivo.

Lehmann CHK, Baranska A, Heidkamp GF, Heger L, Neubert K, Lühr JJ, Hoffmann A, Reimer KC, Brückner C, Beck S, Seeling M, Kießling M, Soulat D, Krug AB, Ravetch JV, Leusen JHW, Nimmerjahn F, Dudziak D.

J Exp Med. 2017 May 1;214(5):1509-1528. doi: 10.1084/jem.20160951. Epub 2017 Apr 7.

13.

Identification of Novel STAT6-Regulated Proteins in Mouse B Cells by Comparative Transcriptome and Proteome Analysis.

Mokada-Gopal L, Boeser A, Lehmann CHK, Drepper F, Dudziak D, Warscheid B, Voehringer D.

J Immunol. 2017 May 1;198(9):3737-3745. doi: 10.4049/jimmunol.1601838. Epub 2017 Mar 27.

14.

Regulation of autoantibody activity by the IL-23-TH17 axis determines the onset of autoimmune disease.

Pfeifle R, Rothe T, Ipseiz N, Scherer HU, Culemann S, Harre U, Ackermann JA, Seefried M, Kleyer A, Uderhardt S, Haugg B, Hueber AJ, Daum P, Heidkamp GF, Ge C, Böhm S, Lux A, Schuh W, Magorivska I, Nandakumar KS, Lönnblom E, Becker C, Dudziak D, Wuhrer M, Rombouts Y, Koeleman CA, Toes R, Winkler TH, Holmdahl R, Herrmann M, Blüml S, Nimmerjahn F, Schett G, Krönke G.

Nat Immunol. 2017 Jan;18(1):104-113. doi: 10.1038/ni.3579. Epub 2016 Nov 7.

15.

Specific phenotype and function of CD56-expressing innate immune cell subsets in human thymus.

Gerstner S, Köhler W, Heidkamp G, Purbojo A, Uchida S, Ekici AB, Heger L, Luetke-Eversloh M, Schubert R, Bader P, Klingebiel T, Koehl U, Mackensen A, Romagnani C, Cesnjevar R, Dudziak D, Ullrich E.

J Leukoc Biol. 2016 Dec;100(6):1297-1310. Epub 2016 Jun 28.

PMID:
27354408
16.

TNF-Mediated Restriction of Arginase 1 Expression in Myeloid Cells Triggers Type 2 NO Synthase Activity at the Site of Infection.

Schleicher U, Paduch K, Debus A, Obermeyer S, König T, Kling JC, Ribechini E, Dudziak D, Mougiakakos D, Murray PJ, Ostuni R, Körner H, Bogdan C.

Cell Rep. 2016 May 3;15(5):1062-1075. doi: 10.1016/j.celrep.2016.04.001. Epub 2016 Apr 21.

17.

Direct Delivery of Antigens to Dendritic Cells via Antibodies Specific for Endocytic Receptors as a Promising Strategy for Future Therapies.

Lehmann CH, Heger L, Heidkamp GF, Baranska A, Lühr JJ, Hoffmann A, Dudziak D.

Vaccines (Basel). 2016 Mar 28;4(2). pii: E8. doi: 10.3390/vaccines4020008. Review.

18.

Cdc42-dependent actin dynamics controls maturation and secretory activity of dendritic cells.

Schulz AM, Stutte S, Hogl S, Luckashenak N, Dudziak D, Leroy C, Forné I, Imhof A, Müller SA, Brakebusch CH, Lichtenthaler SF, Brocker T.

J Cell Biol. 2015 Nov 9;211(3):553-67. doi: 10.1083/jcb.201503128.

19.

Mast-Cell-Derived TNF Amplifies CD8(+) Dendritic Cell Functionality and CD8(+) T Cell Priming.

Dudeck J, Ghouse SM, Lehmann CH, Hoppe A, Schubert N, Nedospasov SA, Dudziak D, Dudeck A.

Cell Rep. 2015 Oct 13;13(2):399-411. doi: 10.1016/j.celrep.2015.08.078. Epub 2015 Sep 24.

20.

Impaired gp100-Specific CD8(+) T-Cell Responses in the Presence of Myeloid-Derived Suppressor Cells in a Spontaneous Mouse Melanoma Model.

Mairhofer DG, Ortner D, Tripp CH, Schaffenrath S, Fleming V, Heger L, Komenda K, Reider D, Dudziak D, Chen S, Becker JC, Flacher V, Stoitzner P.

J Invest Dermatol. 2015 Nov;135(11):2785-2793. doi: 10.1038/jid.2015.241. Epub 2015 Jun 29.

21.

Identification and characterization of the specific murine NK cell subset supporting graft-versus-leukemia- and reducing graft-versus-host-effects.

Meinhardt K, Kroeger I, Bauer R, Ganss F, Ovsiy I, Rothamer J, Büttner M, Atreya I, Waldner M, Bittrich M, Lehmann CH, Rieger MA, Beilhack A, Zeiser R, Edinger M, Dudziak D, Mackensen A, Rehli M, Ullrich E.

Oncoimmunology. 2015 Feb 3;4(1):e981483. eCollection 2015 Jan.

22.

The correlates of mental health of well-educated Polish women in the first pregnancy.

Guszkowska M, Langwald M, Zaremba A, Dudziak D.

J Ment Health. 2014 Dec;23(6):328-32. doi: 10.3109/09638237.2014.971144.

PMID:
25405816
23.

Kit regulates HSC engraftment across the human-mouse species barrier.

Cosgun KN, Rahmig S, Mende N, Reinke S, Hauber I, Schäfer C, Petzold A, Weisbach H, Heidkamp G, Purbojo A, Cesnjevar R, Platz A, Bornhäuser M, Schmitz M, Dudziak D, Hauber J, Kirberg J, Waskow C.

Cell Stem Cell. 2014 Aug 7;15(2):227-38. doi: 10.1016/j.stem.2014.06.001. Epub 2014 Jul 10.

24.

Antigen delivery to CD11c+CD8- dendritic cells induces protective immune responses against experimental melanoma in mice in vivo.

Neubert K, Lehmann CH, Heger L, Baranska A, Staedtler AM, Buchholz VR, Yamazaki S, Heidkamp GF, Eissing N, Zebroski H, Nussenzweig MC, Nimmerjahn F, Dudziak D.

J Immunol. 2014 Jun 15;192(12):5830-8. doi: 10.4049/jimmunol.1300975. Epub 2014 May 14.

25.

Easy performance of 6-color confocal immunofluorescence with 4-laser line microscopes.

Eissing N, Heger L, Baranska A, Cesnjevar R, Büttner-Herold M, Söder S, Hartmann A, Heidkamp GF, Dudziak D.

Immunol Lett. 2014 Sep;161(1):1-5. doi: 10.1016/j.imlet.2014.04.003. Epub 2014 Apr 12.

PMID:
24726673
26.

A humanized mouse identifies the bone marrow as a niche with low therapeutic IgG activity.

Lux A, Seeling M, Baerenwaldt A, Lehmann B, Schwab I, Repp R, Meidenbauer N, Mackensen A, Hartmann A, Heidkamp G, Dudziak D, Nimmerjahn F.

Cell Rep. 2014 Apr 10;7(1):236-48. doi: 10.1016/j.celrep.2014.02.041. Epub 2014 Mar 27.

27.

B cells are critical for autoimmune pathology in Scurfy mice.

Aschermann S, Lehmann CH, Mihai S, Schett G, Dudziak D, Nimmerjahn F.

Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):19042-7. doi: 10.1073/pnas.1313547110. Epub 2013 Nov 5.

28.

Denileukin diftitox (ONTAK) induces a tolerogenic phenotype in dendritic cells and stimulates survival of resting Treg.

Baur AS, Lutz MB, Schierer S, Beltrame L, Theiner G, Zinser E, Ostalecki C, Heidkamp G, Haendle I, Erdmann M, Wiesinger M, Leisgang W, Gross S, Pommer AJ, Kämpgen E, Dudziak D, Steinkasserer A, Cavalieri D, Schuler-Thurner B, Schuler G.

Blood. 2013 Sep 26;122(13):2185-94. doi: 10.1182/blood-2012-09-456988. Epub 2013 Aug 19.

29.

Influence of a single physical exercise class on mood states of pregnant women.

Guszkowska M, Langwald M, Dudziak D, Zaremba A.

J Psychosom Obstet Gynaecol. 2013 Jun;34(2):98-104. doi: 10.3109/0167482X.2013.767794. Epub 2013 May 6.

PMID:
23646888
30.

Dynamic imaging reveals promiscuous crosspresentation of blood-borne antigens to naive CD8+ T cells in the bone marrow.

Milo I, Sapoznikov A, Kalchenko V, Tal O, Krauthgamer R, van Rooijen N, Dudziak D, Jung S, Shakhar G.

Blood. 2013 Jul 11;122(2):193-208. doi: 10.1182/blood-2012-01-401265. Epub 2013 May 1.

31.

AIRE expressing marginal zone dendritic cells balances adaptive immunity and T-follicular helper cell recruitment.

Lindmark E, Chen Y, Georgoudaki AM, Dudziak D, Lindh E, Adams WC, Loré K, Winqvist O, Chambers BJ, Karlsson MC.

J Autoimmun. 2013 May;42:62-70. doi: 10.1016/j.jaut.2012.11.004. Epub 2012 Dec 21.

PMID:
23265639
32.

Advances in cellular therapy: 6th International Symposium on the clinical use of cellular products, March 24 and 25, 2011, Erlangen, Germany.

Ullrich E, Bosch J, Aigner M, Voelkl S, Kroeger I, Hoffmann P, Kreutz M, Dudziak D, Gerbitz A.

Cancer Immunol Immunother. 2012 Mar;61(3):433-43. doi: 10.1007/s00262-011-1190-4. Epub 2011 Dec 27. No abstract available.

PMID:
22200930
33.

Monocyte subsets responsible for immunoglobulin G-dependent effector functions in vivo.

Biburger M, Aschermann S, Schwab I, Lux A, Albert H, Danzer H, Woigk M, Dudziak D, Nimmerjahn F.

Immunity. 2011 Dec 23;35(6):932-44. doi: 10.1016/j.immuni.2011.11.009. Epub 2011 Dec 8.

34.

Antigen targeting to plasmacytoid dendritic cells via Siglec-H inhibits Th cell-dependent autoimmunity.

Loschko J, Heink S, Hackl D, Dudziak D, Reindl W, Korn T, Krug AB.

J Immunol. 2011 Dec 15;187(12):6346-56. doi: 10.4049/jimmunol.1102307. Epub 2011 Nov 11.

35.

Fcγ receptor IIB (FcγRIIB) maintains humoral tolerance in the human immune system in vivo.

Baerenwaldt A, Lux A, Danzer H, Spriewald BM, Ullrich E, Heidkamp G, Dudziak D, Nimmerjahn F.

Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):18772-7. doi: 10.1073/pnas.1111810108. Epub 2011 Nov 7. Erratum in: Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):E4338.

36.

Antigen delivery to plasmacytoid dendritic cells via BST2 induces protective T cell-mediated immunity.

Loschko J, Schlitzer A, Dudziak D, Drexler I, Sandholzer N, Bourquin C, Reindl W, Krug AB.

J Immunol. 2011 Jun 15;186(12):6718-25. doi: 10.4049/jimmunol.1004029. Epub 2011 May 9.

37.

FcγRIV deletion reveals its central role for IgG2a and IgG2b activity in vivo.

Nimmerjahn F, Lux A, Albert H, Woigk M, Lehmann C, Dudziak D, Smith P, Ravetch JV.

Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19396-401. doi: 10.1073/pnas.1014515107. Epub 2010 Oct 25.

38.

Targeting of LcrV virulence protein from Yersinia pestis to dendritic cells protects mice against pneumonic plague.

Do Y, Koh H, Park CG, Dudziak D, Seo P, Mehandru S, Choi JH, Cheong C, Park S, Perlin DS, Powell BS, Steinman RM.

Eur J Immunol. 2010 Oct;40(10):2791-6. doi: 10.1002/eji.201040511.

39.

Route of antigen uptake differentially impacts presentation by dendritic cells and activated monocytes.

Kamphorst AO, Guermonprez P, Dudziak D, Nussenzweig MC.

J Immunol. 2010 Sep 15;185(6):3426-35. doi: 10.4049/jimmunol.1001205. Epub 2010 Aug 20.

40.

Efficient generation of a monoclonal antibody against the human C-type lectin receptor DCIR by targeting murine dendritic cells.

Heidkamp GF, Neubert K, Haertel E, Nimmerjahn F, Nussenzweig MC, Dudziak D.

Immunol Lett. 2010 Aug 16;132(1-2):69-78. doi: 10.1016/j.imlet.2010.06.002. Epub 2010 Jun 8.

41.

Advances in cellular therapy: 5th International Symposium on the clinical use of cellular products, 19 and 20 March 2009, Nürnberg, Germany.

Ullrich E, Bosch J, Aigner M, Völkl S, Dudziak D, Spriewald B, Schuler G, Andreesen R, Mackensen A.

Cancer Immunol Immunother. 2010 Nov;59(11):1745-56. doi: 10.1007/s00262-009-0779-3. Epub 2009 Oct 28. No abstract available.

PMID:
19862524
42.

CD8+ CD205+ splenic dendritic cells are specialized to induce Foxp3+ regulatory T cells.

Yamazaki S, Dudziak D, Heidkamp GF, Fiorese C, Bonito AJ, Inaba K, Nussenzweig MC, Steinman RM.

J Immunol. 2008 Nov 15;181(10):6923-33.

43.

In vivo enzymatic modulation of IgG glycosylation inhibits autoimmune disease in an IgG subclass-dependent manner.

Albert H, Collin M, Dudziak D, Ravetch JV, Nimmerjahn F.

Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):15005-9. doi: 10.1073/pnas.0808248105. Epub 2008 Sep 24.

44.

A subset of dendritic cells induces CD4+ T cells to produce IFN-gamma by an IL-12-independent but CD70-dependent mechanism in vivo.

Soares H, Waechter H, Glaichenhaus N, Mougneau E, Yagita H, Mizenina O, Dudziak D, Nussenzweig MC, Steinman RM.

J Exp Med. 2007 May 14;204(5):1095-106. Epub 2007 Apr 16.

45.

Differential antigen processing by dendritic cell subsets in vivo.

Dudziak D, Kamphorst AO, Heidkamp GF, Buchholz VR, Trumpfheller C, Yamazaki S, Cheong C, Liu K, Lee HW, Park CG, Steinman RM, Nussenzweig MC.

Science. 2007 Jan 5;315(5808):107-11.

46.

A time-dependent dose model for glovebox processing of fissile material.

Wooten HO, Dudziak DJ, Hertel NE, Kornreich DE.

Radiat Prot Dosimetry. 2005;115(1-4):350-6.

PMID:
16381745
47.

Stable T cell-dendritic cell interactions precede the development of both tolerance and immunity in vivo.

Shakhar G, Lindquist RL, Skokos D, Dudziak D, Huang JH, Nussenzweig MC, Dustin ML.

Nat Immunol. 2005 Jul;6(7):707-14. Epub 2005 May 29.

48.

Alternative splicing generates putative soluble CD83 proteins that inhibit T cell proliferation.

Dudziak D, Nimmerjahn F, Bornkamm GW, Laux G.

J Immunol. 2005 Jun 1;174(11):6672-6.

49.

Visualizing dendritic cell networks in vivo.

Lindquist RL, Shakhar G, Dudziak D, Wardemann H, Eisenreich T, Dustin ML, Nussenzweig MC.

Nat Immunol. 2004 Dec;5(12):1243-50. Epub 2004 Nov 14.

PMID:
15543150
50.

Epstein-Barr virus nuclear antigen 2 induces interleukin-18 receptor expression in B cells.

Pagès F, Galon J, Karaschuk G, Dudziak D, Camus M, Lazar V, Camilleri-Broët S, Lagorce-Pagès C, Lebel-Binay S, Laux G, Fridman WH, Henglein B.

Blood. 2005 Feb 15;105(4):1632-9. Epub 2004 Oct 21.

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