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Items: 37


A yeast-based complementation assay elucidates the functional impact of 200 missense variants in human PSAT1.

Sirr A, Lo RS, Cromie GA, Scott AC, Ashmead J, Heyesus M, Dudley AM.

J Inherit Metab Dis. 2020 Feb 19. doi: 10.1002/jimd.12227. [Epub ahead of print]


Data-driven multiscale modeling reveals the role of metabolic coupling for the spatio-temporal growth dynamics of yeast colonies.

Intosalmi J, Scott AC, Hays M, Flann N, Yli-Harja O, Lähdesmäki H, Dudley AM, Skupin A.

BMC Mol Cell Biol. 2019 Dec 19;20(1):59. doi: 10.1186/s12860-019-0234-z.


Computational Inference Software for Tetrad Assembly from Randomly Arrayed Yeast Colonies.

Sakhanenko NA, Cromie GA, Dudley AM, Galas DJ.

G3 (Bethesda). 2019 Jul 9;9(7):2071-2088. doi: 10.1534/g3.119.400166.


Selection of Candida albicans trisomy during oropharyngeal infection results in a commensal-like phenotype.

Forche A, Solis NV, Swidergall M, Thomas R, Guyer A, Beach A, Cromie GA, Le GT, Lowell E, Pavelka N, Berman J, Dudley AM, Selmecki A, Filler SG.

PLoS Genet. 2019 May 15;15(5):e1008137. doi: 10.1371/journal.pgen.1008137. eCollection 2019 May.


A polyploid admixed origin of beer yeasts derived from European and Asian wine populations.

Fay JC, Liu P, Ong GT, Dunham MJ, Cromie GA, Jeffery EW, Ludlow CL, Dudley AM.

PLoS Biol. 2019 Mar 5;17(3):e3000147. doi: 10.1371/journal.pbio.3000147. eCollection 2019 Mar.


Rapid Phenotypic and Genotypic Diversification After Exposure to the Oral Host Niche in Candida albicans.

Forche A, Cromie G, Gerstein AC, Solis NV, Pisithkul T, Srifa W, Jeffery E, Abbey D, Filler SG, Dudley AM, Berman J.

Genetics. 2018 Jul;209(3):725-741. doi: 10.1534/genetics.118.301019. Epub 2018 May 3.


Natural Variation in SER1 and ENA6 Underlie Condition-Specific Growth Defects in Saccharomyces cerevisiae.

Sirr A, Scott AC, Cromie GA, Ludlow CL, Ahyong V, Morgan TS, Gilbert T, Dudley AM.

G3 (Bethesda). 2018 Jan 4;8(1):239-251. doi: 10.1534/g3.117.300392.


Meeting Report on Experimental Approaches to Evolution and Ecology Using Yeast and Other Model Systems.

Jarosz D, Dudley AM.

G3 (Bethesda). 2017 Aug 16. pii: g3.300124.2017. doi: 10.1534/g3.117.300124. [Epub ahead of print]


Transcriptional Profiling of Biofilm Regulators Identified by an Overexpression Screen in Saccharomyces cerevisiae.

Cromie GA, Tan Z, Hays M, Sirr A, Jeffery EW, Dudley AM.

G3 (Bethesda). 2017 Aug 7;7(8):2845-2854. doi: 10.1534/g3.117.042440.


The State of Systems Genetics in 2017.

Baliga NS, Björkegren JL, Boeke JD, Boutros M, Crawford NP, Dudley AM, Farber CR, Jones A, Levey AI, Lusis AJ, Mak HC, Nadeau JH, Noyes MB, Petretto E, Seyfried NT, Steinmetz LM, Vonesch SC.

Cell Syst. 2017 Jan 25;4(1):7-15. doi: 10.1016/j.cels.2017.01.005.


Dissecting Gene Expression Changes Accompanying a Ploidy-Based Phenotypic Switch.

Cromie GA, Tan Z, Hays M, Jeffery EW, Dudley AM.

G3 (Bethesda). 2017 Jan 5;7(1):233-246. doi: 10.1534/g3.116.036160.


Independent Origins of Yeast Associated with Coffee and Cacao Fermentation.

Ludlow CL, Cromie GA, Garmendia-Torres C, Sirr A, Hays M, Field C, Jeffery EW, Fay JC, Dudley AM.

Curr Biol. 2016 Apr 4;26(7):965-71. doi: 10.1016/j.cub.2016.02.012. Epub 2016 Mar 24.


Proteomic Analysis of Dhh1 Complexes Reveals a Role for Hsp40 Chaperone Ydj1 in Yeast P-Body Assembly.

Cary GA, Vinh DB, May P, Kuestner R, Dudley AM.

G3 (Bethesda). 2015 Sep 21;5(11):2497-511. doi: 10.1534/g3.115.021444.


Aneuploidy: Tolerating Tolerance.

Cromie GA, Dudley AM.

Curr Biol. 2015 Aug 31;25(17):R771-3. doi: 10.1016/j.cub.2015.06.056.


Allelic variation, aneuploidy, and nongenetic mechanisms suppress a monogenic trait in yeast.

Sirr A, Cromie GA, Jeffery EW, Gilbert TL, Ludlow CL, Scott AC, Dudley AM.

Genetics. 2015 Jan;199(1):247-62. doi: 10.1534/genetics.114.170563. Epub 2014 Nov 13.


Unidirectional P-body transport during the yeast cell cycle.

Garmendia-Torres C, Skupin A, Michael SA, Ruusuvuori P, Kuwada NJ, Falconnet D, Cary GA, Hansen C, Wiggins PA, Dudley AM.

PLoS One. 2014 Jun 11;9(6):e99428. doi: 10.1371/journal.pone.0099428. eCollection 2014.


BEST: barcode enabled sequencing of tetrads.

Scott AC, Ludlow CL, Cromie GA, Dudley AM.

J Vis Exp. 2014 May 1;(87). doi: 10.3791/51401.


Identification and characterization of a drug-sensitive strain enables puromycin-based translational assays in Saccharomyces cerevisiae.

Cary GA, Yoon SH, Torres CG, Wang K, Hays M, Ludlow C, Goodlett DR, Dudley AM.

Yeast. 2014 May;31(5):167-78. doi: 10.1002/yea.3007. Epub 2014 Mar 19.


Quantitative analysis of colony morphology in yeast.

Ruusuvuori P, Lin J, Scott AC, Tan Z, Sorsa S, Kallio A, Nykter M, Yli-Harja O, Shmulevich I, Dudley AM.

Biotechniques. 2014 Jan;56(1):18-27. doi: 10.2144/000114123.


POMO--Plotting Omics analysis results for Multiple Organisms.

Lin J, Kreisberg R, Kallio A, Dudley AM, Nykter M, Shmulevich I, May P, Autio R.

BMC Genomics. 2013 Dec 24;14:918. doi: 10.1186/1471-2164-14-918.


Genomic sequence diversity and population structure of Saccharomyces cerevisiae assessed by RAD-seq.

Cromie GA, Hyma KE, Ludlow CL, Garmendia-Torres C, Gilbert TL, May P, Huang AA, Dudley AM, Fay JC.

G3 (Bethesda). 2013 Dec 9;3(12):2163-71. doi: 10.1534/g3.113.007492.


Aneuploidy underlies a multicellular phenotypic switch.

Tan Z, Hays M, Cromie GA, Jeffery EW, Scott AC, Ahyong V, Sirr A, Skupin A, Dudley AM.

Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12367-72. doi: 10.1073/pnas.1301047110. Epub 2013 Jun 28.


High-throughput tetrad analysis.

Ludlow CL, Scott AC, Cromie GA, Jeffery EW, Sirr A, May P, Lin J, Gilbert TL, Hays M, Dudley AM.

Nat Methods. 2013 Jul;10(7):671-5. doi: 10.1038/nmeth.2479. Epub 2013 May 12.


Genetics. Systems genetics.

Nadeau JH, Dudley AM.

Science. 2011 Feb 25;331(6020):1015-6. doi: 10.1126/science.1203869. No abstract available.


Surface plasmon resonance biosensor for rapid label-free detection of microribonucleic acid at subfemtomole level.

Sípová H, Zhang S, Dudley AM, Galas D, Wang K, Homola J.

Anal Chem. 2010 Dec 15;82(24):10110-5. doi: 10.1021/ac102131s. Epub 2010 Nov 19.


Evaluation of methods for detection of fluorescence labeled subcellular objects in microscope images.

Ruusuvuori P, Aijö T, Chowdhury S, Garmendia-Torres C, Selinummi J, Birbaumer M, Dudley AM, Pelkmans L, Yli-Harja O.

BMC Bioinformatics. 2010 May 13;11:248. doi: 10.1186/1471-2105-11-248.


Learning a prior on regulatory potential from eQTL data.

Lee SI, Dudley AM, Drubin D, Silver PA, Krogan NJ, Pe'er D, Koller D.

PLoS Genet. 2009 Jan;5(1):e1000358. doi: 10.1371/journal.pgen.1000358. Epub 2009 Jan 30.


Model-driven analysis of experimentally determined growth phenotypes for 465 yeast gene deletion mutants under 16 different conditions.

Snitkin ES, Dudley AM, Janse DM, Wong K, Church GM, Segrè D.

Genome Biol. 2008;9(9):R140. doi: 10.1186/gb-2008-9-9-r140. Epub 2008 Sep 22.


Identifying regulatory mechanisms using individual variation reveals key role for chromatin modification.

Lee SI, Pe'er D, Dudley AM, Church GM, Koller D.

Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14062-7. Epub 2006 Sep 12.


A global view of pleiotropy and phenotypically derived gene function in yeast.

Dudley AM, Janse DM, Tanay A, Shamir R, Church GM.

Mol Syst Biol. 2005;1:2005.0001. Epub 2005 Mar 29.


Factors associated with treatment compliance in young people following an emergency department presentation for deliberate self-harm.

Clarke AR, Schnieden V, Hamilton BA, Dudley AM, Beard J, Einfeld SL, Buss R, Tobin M, Knowles M, Stevens G, Gibbs N.

Arch Suicide Res. 2004;8(2):147-52.


Predicting phenotype from patterns of annotation.

King OD, Lee JC, Dudley AM, Janse DM, Church GM, Roth FP.

Bioinformatics. 2003;19 Suppl 1:i183-9.


Measuring absolute expression with microarrays with a calibrated reference sample and an extended signal intensity range.

Dudley AM, Aach J, Steffen MA, Church GM.

Proc Natl Acad Sci U S A. 2002 May 28;99(11):7554-9.


T7 RNA polymerase-dependent expression of COXII in yeast mitochondria.

Pinkham JL, Dudley AM, Mason TL.

Mol Cell Biol. 1994 Jul;14(7):4643-52.

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