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Long-term Quality of Life and Gastrointestinal Functional Outcomes After Pancreaticoduodenectomy.

Allen CJ, Yakoub D, Macedo FI, Dosch AR, Brosch J, Dudeja V, Ayala R, Merchant NB.

Ann Surg. 2018 Oct;268(4):657-664. doi: 10.1097/SLA.0000000000002962.


NFκB in Pancreatic Stellate Cells Reduces Infiltration of Tumors by Cytotoxic T Cells and Killing of Cancer Cells, via Up-regulation of CXCL12.

Garg B, Giri B, Modi S, Sethi V, Castro I, Umland O, Ban Y, Lavania S, Dawra R, Banerjee S, Vickers S, Merchant NB, Chen SX, Gilboa E, Ramakrishnan S, Saluja A, Dudeja V.

Gastroenterology. 2018 Sep;155(3):880-891.e8. doi: 10.1053/j.gastro.2018.05.051. Epub 2018 Jul 29.


GRP78-mediated antioxidant response and ABC transporter activity confers chemoresistance to pancreatic cancer cells.

Dauer P, Sharma NS, Gupta VK, Nomura A, Dudeja V, Saluja A, Banerjee S.

Mol Oncol. 2018 Sep;12(9):1498-1512. doi: 10.1002/1878-0261.12322. Epub 2018 Aug 7.


Gut Microbiota Promotes Tumor Growth in Mice by Modulating Immune Response.

Sethi V, Kurtom S, Tarique M, Lavania S, Malchiodi Z, Hellmund L, Zhang L, Sharma U, Giri B, Garg B, Ferrantella A, Vickers SM, Banerjee S, Dawra R, Roy S, Ramakrishnan S, Saluja A, Dudeja V.

Gastroenterology. 2018 Jul;155(1):33-37.e6. doi: 10.1053/j.gastro.2018.04.001. Epub 2018 Apr 7.


Pancreatitis: A Tale of Two Proteases.

Nikam A, Dawra R, Saluja A, Dudeja V.

Gastroenterology. 2018 Feb;154(3):482-484. doi: 10.1053/j.gastro.2018.01.017. Epub 2018 Jan 11. No abstract available.


Inactivation of Cancer-Associated-Fibroblasts Disrupts Oncogenic Signaling in Pancreatic Cancer Cells and Promotes Its Regression.

Dauer P, Zhao X, Gupta VK, Sharma N, Kesh K, Gnamlin P, Dudeja V, Vickers SM, Banerjee S, Saluja A.

Cancer Res. 2018 Mar 1;78(5):1321-1333. doi: 10.1158/0008-5472.CAN-17-2320. Epub 2017 Dec 19.


NFκB-Mediated Invasiveness in CD133+ Pancreatic TICs Is Regulated by Autocrine and Paracrine Activation of IL1 Signaling.

Nomura A, Gupta VK, Dauer P, Sharma NS, Dudeja V, Merchant N, Saluja AK, Banerjee S.

Mol Cancer Res. 2018 Jan;16(1):162-172. doi: 10.1158/1541-7786.MCR-17-0221. Epub 2017 Sep 28.


Inhibition of hypoxic response decreases stemness and reduces tumorigenic signaling due to impaired assembly of HIF1 transcription complex in pancreatic cancer.

McGinn O, Gupta VK, Dauer P, Arora N, Sharma N, Nomura A, Dudeja V, Saluja A, Banerjee S.

Sci Rep. 2017 Aug 11;7(1):7872. doi: 10.1038/s41598-017-08447-3.


The Impact of Surgeon Volume on Outcomes After Pancreaticoduodenectomy: a Meta-analysis.

Macedo FIB, Jayanthi P, Mowzoon M, Yakoub D, Dudeja V, Merchant N.

J Gastrointest Surg. 2017 Oct;21(10):1723-1731. doi: 10.1007/s11605-017-3498-7. Epub 2017 Jul 25.


Genetics of pancreatic cyst-cancer progression: standing on the shoulders of giants.

Giri B, Sethi V, Dudeja V, Banerjee S, Livingstone A, Saluja A.

Curr Opin Gastroenterol. 2017 Sep;33(5):404-410. doi: 10.1097/MOG.0000000000000382. Review.


Morphine worsens the severity and prevents pancreatic regeneration in mouse models of acute pancreatitis.

Barlass U, Dutta R, Cheema H, George J, Sareen A, Dixit A, Yuan Z, Giri B, Meng J, Banerjee S, Banerjee S, Dudeja V, Dawra RK, Roy S, Saluja AK.

Gut. 2018 Apr;67(4):600-602. doi: 10.1136/gutjnl-2017-313717. Epub 2017 Jun 22.


"Heat shock protein 70 in pancreatic diseases: Friend or foe".

Giri B, Sethi V, Modi S, Garg B, Banerjee S, Saluja A, Dudeja V.

J Surg Oncol. 2017 Jul;116(1):114-122. doi: 10.1002/jso.24653. Epub 2017 May 22. Review.


Insights into the Pathogenesis of Pancreatic Cystic Neoplasms.

Sethi V, Giri B, Saluja A, Dudeja V.

Dig Dis Sci. 2017 Jul;62(7):1778-1786. doi: 10.1007/s10620-017-4603-1. Epub 2017 May 12. Review.


Predicting Residual Disease in Incidental Gallbladder Cancer: Risk Stratification for Modified Treatment Strategies.

Creasy JM, Goldman DA, Gonen M, Dudeja V, Askan G, Basturk O, Balachandran VP, Allen PJ, DeMatteo RP, D'Angelica MI, Jarnagin WR, Peter Kingham T.

J Gastrointest Surg. 2017 Aug;21(8):1254-1261. doi: 10.1007/s11605-017-3436-8. Epub 2017 May 8.


Inhibition of Sp1 prevents ER homeostasis and causes cell death by lysosomal membrane permeabilization in pancreatic cancer.

Dauer P, Gupta VK, McGinn O, Nomura A, Sharma NS, Arora N, Giri B, Dudeja V, Saluja AK, Banerjee S.

Sci Rep. 2017 May 8;7(1):1564. doi: 10.1038/s41598-017-01696-2.


Why Do Long-Distance Travelers Have Improved Pancreatectomy Outcomes?

Jindal M, Zheng C, Quadri HS, Ihemelandu CU, Hong YK, Smith AK, Dudeja V, Shara NM, Johnson LB, Al-Refaie WB.

J Am Coll Surg. 2017 Aug;225(2):216-225. doi: 10.1016/j.jamcollsurg.2017.04.003. Epub 2017 Apr 14.


Systemic Chemotherapy Combined with Resection for Locally Advanced Gallbladder Carcinoma: Surgical and Survival Outcomes.

Creasy JM, Goldman DA, Dudeja V, Lowery MA, Cercek A, Balachandran VP, Allen PJ, DeMatteo RP, Kingham TP, D'Angelica MI, Jarnagin WR.

J Am Coll Surg. 2017 May;224(5):906-916. doi: 10.1016/j.jamcollsurg.2016.12.058. Epub 2017 Feb 13.


Downregulation of Sp1 by Minnelide leads to decrease in HSP70 and decrease in tumor burden of gastric cancer.

Arora N, Alsaied O, Dauer P, Majumder K, Modi S, Giri B, Dudeja V, Banerjee S, Von Hoff D, Saluja A.

PLoS One. 2017 Feb 13;12(2):e0171827. doi: 10.1371/journal.pone.0171827. eCollection 2017.


Minnelide Inhibits Androgen Dependent, Castration Resistant Prostate Cancer Growth by Decreasing Expression of Androgen Receptor Full Length and Splice Variants.

Isharwal S, Modi S, Arora N, Uhlrich C 3rd, Giri B, Barlass U, Soubra A, Chugh R, Dehm SM, Dudeja V, Saluja A, Banerjee S, Konety B.

Prostate. 2017 May;77(6):584-596. doi: 10.1002/pros.23298. Epub 2017 Feb 1.


Modulation of post-translational modifications in β-catenin and LRP6 inhibits Wnt signaling pathway in pancreatic cancer.

Garg B, Giri B, Majumder K, Dudeja V, Banerjee S, Saluja A.

Cancer Lett. 2017 Mar 1;388:64-72. doi: 10.1016/j.canlet.2016.11.026. Epub 2016 Dec 3.


Inhibition of NF-kappa B pathway leads to deregulation of epithelial-mesenchymal transition and neural invasion in pancreatic cancer.

Nomura A, Majumder K, Giri B, Dauer P, Dudeja V, Roy S, Banerjee S, Saluja AK.

Lab Invest. 2016 Dec;96(12):1268-1278. doi: 10.1038/labinvest.2016.109. Epub 2016 Oct 24.


Comprehensive analysis of microRNA signature of mouse pancreatic acini: overexpression of miR-21-3p in acute pancreatitis.

Dixit AK, Sarver AE, Yuan Z, George J, Barlass U, Cheema H, Sareen A, Banerjee S, Dudeja V, Dawra R, Subramanian S, Saluja AK.

Am J Physiol Gastrointest Liver Physiol. 2016 Nov 1;311(5):G974-G980. doi: 10.1152/ajpgi.00191.2016. Epub 2016 Sep 29.


Release of Cathepsin B in Cytosol Causes Cell Death in Acute Pancreatitis.

Talukdar R, Sareen A, Zhu H, Yuan Z, Dixit A, Cheema H, George J, Barlass U, Sah R, Garg SK, Banerjee S, Garg P, Dudeja V, Dawra R, Saluja AK.

Gastroenterology. 2016 Oct;151(4):747-758.e5. doi: 10.1053/j.gastro.2016.06.042. Epub 2016 Aug 9.


Is age just a number: pancreaticoduodenectomy in elderly patients?

Dudeja V, Livingstone A.

Hepatobiliary Pancreat Dis Int. 2016 Aug;15(4):346-7. No abstract available.


Microenvironment mediated alterations to metabolic pathways confer increased chemo-resistance in CD133+ tumor initiating cells.

Nomura A, Dauer P, Gupta V, McGinn O, Arora N, Majumdar K, Uhlrich C 3rd, Dalluge J, Dudeja V, Saluja A, Banerjee S.

Oncotarget. 2016 Aug 30;7(35):56324-56337. doi: 10.18632/oncotarget.10838.


Evolution of novel therapeutic options for pancreatic cancer.

Saluja AK, Dudeja V, Banerjee S.

Curr Opin Gastroenterol. 2016 Jul 21. [Epub ahead of print]


Effect of MRI Versus MDCT on Milan Criteria Scores and Liver Transplantation Eligibility.

Rostambeigi N, Taylor AJ, Golzarian J, Jensen EH, Pruett TL, Dudeja V, D'Souza D.

AJR Am J Roentgenol. 2016 Apr;206(4):726-33. doi: 10.2214/AJR.15.14642. Epub 2016 Jan 21. Erratum in: AJR Am J Roentgenol. 2016 Jul;207 (1):226.


Minnelide effectively eliminates CD133(+) side population in pancreatic cancer.

Nomura A, McGinn O, Dudeja V, Sangwan V, Saluja AK, Banerjee S.

Mol Cancer. 2015 Nov 23;14:200. doi: 10.1186/s12943-015-0470-6.


A Novel Immunocompetent Mouse Model of Pancreatic Cancer with Robust Stroma: a Valuable Tool for Preclinical Evaluation of New Therapies.

Majumder K, Arora N, Modi S, Chugh R, Nomura A, Giri B, Dawra R, Ramakrishnan S, Banerjee S, Saluja A, Dudeja V.

J Gastrointest Surg. 2016 Jan;20(1):53-65; discussion 65. doi: 10.1007/s11605-015-2985-y. Epub 2015 Nov 18.


Neutrophil Extracellular Traps Provide a Grip on the Enigmatic Pathogenesis of Acute Pancreatitis.

Korhonen JT, Dudeja V, Dawra R, Kubes P, Saluja A.

Gastroenterology. 2015 Dec;149(7):1682-5. doi: 10.1053/j.gastro.2015.10.027. Epub 2015 Oct 23. No abstract available.


Minnelide Overcomes Oxaliplatin Resistance by Downregulating the DNA Repair Pathway in Pancreatic Cancer.

Modi S, Kir D, Giri B, Majumder K, Arora N, Dudeja V, Banerjee S, Saluja AK.

J Gastrointest Surg. 2016 Jan;20(1):13-23; discussion 23-4. doi: 10.1007/s11605-015-3000-3. Epub 2015 Oct 26.


Impaired Synthesis of Stromal Components in Response to Minnelide Improves Vascular Function, Drug Delivery, and Survival in Pancreatic Cancer.

Banerjee S, Modi S, McGinn O, Zhao X, Dudeja V, Ramakrishnan S, Saluja AK.

Clin Cancer Res. 2016 Jan 15;22(2):415-25. doi: 10.1158/1078-0432.CCR-15-1155. Epub 2015 Sep 24.


Triptolide abrogates growth of colon cancer and induces cell cycle arrest by inhibiting transcriptional activation of E2F.

Oliveira A, Beyer G, Chugh R, Skube SJ, Majumder K, Banerjee S, Sangwan V, Li L, Dawra R, Subramanian S, Saluja A, Dudeja V.

Lab Invest. 2015 Jun;95(6):648-659. doi: 10.1038/labinvest.2015.46. Epub 2015 Apr 20.


Primary and liver metastasis-derived cell lines from KrasG12D; Trp53R172H; Pdx-1 Cre animals undergo apoptosis in response to triptolide.

Sangwan V, Banerjee S, Jensen KM, Chen Z, Chugh R, Dudeja V, Vickers SM, Saluja AK.

Pancreas. 2015 May;44(4):583-9. doi: 10.1097/MPA.0000000000000317.


CD133 initiates tumors, induces epithelial-mesenchymal transition and increases metastasis in pancreatic cancer.

Nomura A, Banerjee S, Chugh R, Dudeja V, Yamamoto M, Vickers SM, Saluja AK.

Oncotarget. 2015 Apr 10;6(10):8313-22.


Premalignant cystic neoplasms of the pancreas.

Dudeja V, Allen PJ.

Semin Oncol. 2015 Feb;42(1):70-85. doi: 10.1053/j.seminoncol.2014.12.007. Epub 2014 Dec 9. Review.


Endoplasmic reticulum stress is chronically activated in chronic pancreatitis.

Sah RP, Garg SK, Dixit AK, Dudeja V, Dawra RK, Saluja AK.

J Biol Chem. 2014 Oct 3;289(40):27551-61. doi: 10.1074/jbc.M113.528174. Epub 2014 Jul 30.


To study the effect of orbital sling on post operative vision in cases of maxillary carcinoma undergoing total maxillectomy.

Shukla A, Dudeja V.

Indian J Otolaryngol Head Neck Surg. 2014 Jun;66(2):196-9. doi: 10.1007/s12070-014-0715-5. Epub 2014 Mar 25.


Triptolide activates unfolded protein response leading to chronic ER stress in pancreatic cancer cells.

Mujumdar N, Banerjee S, Chen Z, Sangwan V, Chugh R, Dudeja V, Yamamoto M, Vickers SM, Saluja AK.

Am J Physiol Gastrointest Liver Physiol. 2014 Jun 1;306(11):G1011-20. doi: 10.1152/ajpgi.00466.2013. Epub 2014 Apr 3.


Triptolide sensitizes pancreatic cancer cells to TRAIL-induced activation of the death receptor pathway.

Chen Z, Sangwan V, Banerjee S, Chugh R, Dudeja V, Vickers SM, Saluja AK.

Cancer Lett. 2014 Jun 28;348(1-2):156-66. doi: 10.1016/j.canlet.2014.03.016. Epub 2014 Mar 21.


CD133+ tumor initiating cells in a syngenic murine model of pancreatic cancer respond to Minnelide.

Banerjee S, Nomura A, Sangwan V, Chugh R, Dudeja V, Vickers SM, Saluja A.

Clin Cancer Res. 2014 May 1;20(9):2388-99. doi: 10.1158/1078-0432.CCR-13-2947. Epub 2014 Mar 14.


Triptolide-induced cell death in pancreatic cancer is mediated by O-GlcNAc modification of transcription factor Sp1.

Banerjee S, Sangwan V, McGinn O, Chugh R, Dudeja V, Vickers SM, Saluja AK.

J Biol Chem. 2013 Nov 22;288(47):33927-38. doi: 10.1074/jbc.M113.500983. Epub 2013 Oct 15.


miR-204 mediated loss of Myeloid cell leukemia-1 results in pancreatic cancer cell death.

Chen Z, Sangwan V, Banerjee S, Mackenzie T, Dudeja V, Li X, Wang H, Vickers SM, Saluja AK.

Mol Cancer. 2013 Sep 11;12(1):105. doi: 10.1186/1476-4598-12-105.


Total pancreatectomy with islet autotransplantation in patients with malignancy: are we there yet?

Dudeja V, Beilman GJ, Vickers SM.

Ann Surg. 2013 Aug;258(2):219-20. doi: 10.1097/SLA.0b013e31829c4a1b. No abstract available.


Relevance of animal models of pancreatic cancer and pancreatitis to human disease.

Saluja AK, Dudeja V.

Gastroenterology. 2013 Jun;144(6):1194-8. doi: 10.1053/j.gastro.2013.01.070. Review. No abstract available.


Disparities in pancreas cancer care.

Abraham A, Al-Refaie WB, Parsons HM, Dudeja V, Vickers SM, Habermann EB.

Ann Surg Oncol. 2013 Jun;20(6):2078-87. doi: 10.1245/s10434-012-2843-z. Epub 2013 Apr 12.


Neoadjuvant chemoradiotherapy for locally advanced pancreas cancer rarely leads to radiological evidence of tumour regression.

Dudeja V, Greeno EW, Walker SP, Jensen EH.

HPB (Oxford). 2013 Sep;15(9):661-7. doi: 10.1111/hpb.12015. Epub 2012 Dec 2.


Triptolide-mediated cell death in neuroblastoma occurs by both apoptosis and autophagy pathways and results in inhibition of nuclear factor-kappa B activity.

Krosch TC, Sangwan V, Banerjee S, Mujumdar N, Dudeja V, Saluja AK, Vickers SM.

Am J Surg. 2013 Apr;205(4):387-96. doi: 10.1016/j.amjsurg.2013.01.008. Epub 2013 Feb 19.


Cerulein-induced chronic pancreatitis does not require intra-acinar activation of trypsinogen in mice.

Sah RP, Dudeja V, Dawra RK, Saluja AK.

Gastroenterology. 2013 May;144(5):1076-1085.e2. doi: 10.1053/j.gastro.2013.01.041. Epub 2013 Jan 24.

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