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Items: 9

1.

Genome-wide CRISPR Screens in T Helper Cells Reveal Pervasive Crosstalk between Activation and Differentiation.

Henriksson J, Chen X, Gomes T, Ullah U, Meyer KB, Miragaia R, Duddy G, Pramanik J, Yusa K, Lahesmaa R, Teichmann SA.

Cell. 2019 Feb 7;176(4):882-896.e18. doi: 10.1016/j.cell.2018.11.044. Epub 2019 Jan 10.

2.

Phos-tag analysis of Rab10 phosphorylation by LRRK2: a powerful assay for assessing kinase function and inhibitors.

Ito G, Katsemonova K, Tonelli F, Lis P, Baptista MA, Shpiro N, Duddy G, Wilson S, Ho PW, Ho SL, Reith AD, Alessi DR.

Biochem J. 2016 Sep 1;473(17):2671-85. doi: 10.1042/BCJ20160557. Epub 2016 Jul 29.

3.

Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases.

Steger M, Tonelli F, Ito G, Davies P, Trost M, Vetter M, Wachter S, Lorentzen E, Duddy G, Wilson S, Baptista MA, Fiske BK, Fell MJ, Morrow JA, Reith AD, Alessi DR, Mann M.

Elife. 2016 Jan 29;5. pii: e12813. doi: 10.7554/eLife.12813.

4.

Targeting apoptosis signalling kinase-1 (ASK-1) does not prevent the development of neuropathy in streptozotocin-induced diabetic mice.

Newton VL, Ali S, Duddy G, Whitmarsh AJ, Gardiner NJ.

PLoS One. 2014 Oct 16;9(10):e107437. doi: 10.1371/journal.pone.0107437. eCollection 2014.

5.

Characterisation of a K390R ITK kinase dead transgenic mouse--implications for ITK as a therapeutic target.

Deakin A, Duddy G, Wilson S, Harrison S, Latcham J, Fulleylove M, Fung S, Smith J, Pedrick M, McKevitt T, Felton L, Morley J, Quint D, Fattah D, Hayes B, Gough J, Solari R.

PLoS One. 2014 Sep 24;9(9):e107490. doi: 10.1371/journal.pone.0107490. eCollection 2014.

6.

Evaluation of expression and function of the H+/myo-inositol transporter HMIT.

Di Daniel E, Mok MH, Mead E, Mutinelli C, Zambello E, Caberlotto LL, Pell TJ, Langmead CJ, Shah AJ, Duddy G, Kew JN, Maycox PR.

BMC Cell Biol. 2009 Jul 16;10:54. doi: 10.1186/1471-2121-10-54.

7.

Edg8/S1P5: an oligodendroglial receptor with dual function on process retraction and cell survival.

Jaillard C, Harrison S, Stankoff B, Aigrot MS, Calver AR, Duddy G, Walsh FS, Pangalos MN, Arimura N, Kaibuchi K, Zalc B, Lubetzki C.

J Neurosci. 2005 Feb 9;25(6):1459-69.

8.

BACE1 (beta-secretase) transgenic and knockout mice: identification of neurochemical deficits and behavioral changes.

Harrison SM, Harper AJ, Hawkins J, Duddy G, Grau E, Pugh PL, Winter PH, Shilliam CS, Hughes ZA, Dawson LA, Gonzalez MI, Upton N, Pangalos MN, Dingwall C.

Mol Cell Neurosci. 2003 Nov;24(3):646-55.

PMID:
14664815
9.

Molecular and pharmacological characterization of genes encoding urotensin-II peptides and their cognate G-protein-coupled receptors from the mouse and monkey.

Elshourbagy NA, Douglas SA, Shabon U, Harrison S, Duddy G, Sechler JL, Ao Z, Maleeff BE, Naselsky D, Disa J, Aiyar NV.

Br J Pharmacol. 2002 May;136(1):9-22.

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